Activation of A3 adenosine receptors on human eosinophils elevates intracellular calcium

Blood

Volumn 88, Issue 9, 1996, Pages 3569-3574

  Kohno, Yutaka ^a   Ji, Xiao Duo ^a   Mawhorter, Steve D ^a   Koshiba, Masahiro ^a   Jacobson, Kenneth A ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 CHLORO 6 N (3 IODOBENZYL)ADENOSINE 5' N METHYLCARBOXAMIDE; 2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); 6 N BENZYLADENOSINE; ADENOSINE; ADENOSINE A1 RECEPTOR; ADENOSINE A2 RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; CALCIUM ION; UNCLASSIFIED DRUG; ADENOSINE RECEPTOR; CALCIUM; COMPLEMENTARY DNA; DRUG DERIVATIVE; N(6) (4 AMINO 3 IODOBENZYL)ADENOSINE 5' N METHYLURONAMIDE; N(6)-(4-AMINO-3-IODOBENZYL)ADENOSINE-5'-N-METHYLURONAMIDE;

ALLERGIC DISEASE; APOPTOSIS; ARTICLE; ASTHMA; CALCIUM CELL LEVEL; EOSINOPHIL; HUMAN; HUMAN CELL; HYPEREOSINOPHILIA; INFLAMMATION; PRIORITY JOURNAL; CELL CULTURE; DRUG POTENTIATION; GENETICS; ISOLATION AND PURIFICATION; METABOLISM; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

ADENOSINE; CALCIUM; CELLS, CULTURED; DNA, COMPLEMENTARY; EOSINOPHILS; HUMANS; POLYMERASE CHAIN REACTION; RECEPTORS, PURINERGIC P1; SIGNAL TRANSDUCTION;

EID: 0029661826     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v88.9.3569.bloodjournal8893569     Document Type: Article

References (39)

1. Gleich GJ: The eosinophil and bronchial asthma: Current understanding. J Allergy Clin Immunol 85:422, 1990
2. Weller PF: The immunobiology of eosinophils. N Engl J Med 324:1110, 1991
3. Silberstein DS: Eosinophil function in health and disease. Crit Rev Oncol Hematol 19:47, 1995
4. Discombe G: Criteria of eosinophilia. Lancet 1:195, 1946
5. Horn BR, Robin ED, Theodore J, VanKessel A: Total eosinophil counts in the management of bronchial asthma. N Engl J Med 292:1152, 1975
6. Bousquet J, Chanez P, Lacoste JY, Barneon G, Ghavanian N, Enander I, Venhe P, Ahlstedt S, Simony-Lafontaine J, Godard P: Eosinophilic inflammation in asthma. N Engl J Med 323:1033, 1990
7. Filley WV, Holley KE, Kephart GM, Gleich GJ: Identification by immunofluorescence of eosinophil granule major basic protein in lung tissue of patients with bronchial asthma. Lancet 2:11, 1982
8. Fukuda T, Dunnette SL, Reed CE, Ackerman SJ, Peters MS, Gleich GJ: Increased numbers of hypodense eosinophils in the blood of patients with bronchial asthma. Am Rev Respir Dis 132:981, 1985
9. Koshino T, Morita Y, Ito K, Teshima S, Sano Y: Activation of bone marrow eosinophils in asthma. Chest 103:1931, 1993
10. O'Donnell MC, Ackerman SJ, Gleich GJ, Thomas LL: Activation of basophil and mast cell histamine release by eosinophil granule major basic protein. J Exp Med 157:1981, 1983
11. Church MK, Holgate ST: Adenosine-induced bronchoconstriction and its inhibition by nedocromil sodium. J Allergy Clin Immunol 92:190, 1993
12. Ott I, Lohse MJ, Klotz KN, Vogt-Moykopf I, Schwabe U: Effect of adenosine on histamine release from human lung fragments. Int Arch Allergy Clin Immunol 98:50 1992
13. Bjorck T, Gustafsson LE, Dahlen SE: Isolated bronchi from asthmatics are hyperresponsive to adenosine, which apparently acts indirectly by liberation of leukotrienes and histamine. Am Rev Respir Dis 145:1087, 1992
14. Driver AG, Kukoly CA, Ali S, Mustafa SJ: Adenosine in bronchoalveolar lavage fluid in asthma. Am Rev Respir Dis 148:91, 1993
15. Weller PF, Lee CW, Foster DW, Corey EJ, Austen KF, Lewis RA: Generation and metabolism of 5-lipoxygenase pathway leukotrienes by human eosinophils: Predominant production of leukotriene C4. Proc Natl Acad Sci USA 80:7626, 1983
16. Lewis RA, Austen KF: The biologically active leukotrienes: Biosynthesis, metabolism, receptors, and pharmacology. J Clin Invest 73:889, 1984
17. Howell RE, Gaudette RF, Raynor MC, Warner AT, Muehsam WT, Schenden JA, Perumattam J, Hiner RN, Kinnier WJ: Mechanisms of xanthine actions in models of asthma, in Jacobsen KA, Daly JW, Manganiello V (eds): Purines in Cellular Signaling: Targets for New Drugs. New York, NY, Springer-Verlag, 1990 p 370
18. Zhou QY, Li CY, Olah ME, Johnson RA, Stiles GL, Civelli O: Molecular cloning and characterization of an adenosine receptor: The A3 adenosine receptor. Proc Natl Acad Sci USA 89:7432, 1992
19. Meyerhof W, Muller-Brechlin R, Richter D: Molecular cloning of a novel putative G-protein coupled receptor expressed during rat spermiogenesis. FEBS Lett 284:155, 1991
20. Bai TR, Weir T, Walker B, Salvatore CA, Johnson RG, Jacobson MA: Localization of adenosine-A3 receptors by in-situ hybridization in human lung. FASEB J 8:A800, 1994
21. Hansel TT, Pound JD, Pilling D, Kitas GD, Salmon M, Gentle TA, Lee SS, Thompson RA: Purification of human eosinophils by negative selection using immunomagnetic beads. J Immunol Methods 122:97, 1989
22. Chomczynski P, Sacchi N: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162:156, 1987
23. 3 adenosine receptor. Biochem Biophys Acta 1179:105, 1993
24. 3 adenosine receptor. Proc Natl Acad Sci USA 90:10365, 1993
25. 125I] AB-MECA, a high affinity radioligand for the rat A3 adenosine receptor. Mol Pharmacol 45:978, 1994
26. 3-adenosine receptors. J Med Chem 37:3614, 1994
27. Ji X-D, Melman N, Jacobson KA: Interactions of flavonoids and other phytochemicals with adenosine receptors. J Med Chem 39:781, 1996
28. 3-adenosine receptors: Design of selective ligands and therapeutic prospects. Drugs Future 20:689, 1995
29. 3 receptor agonists. Biochem Biophys Res Comm 219:904, 1996
30. Fukuda T, Ackerman SJ, Reed CE, Peters MS, Dunnette SL, Gleich GJ: Calcium ionophore A23187 calcium-dependent cytolytic degranulation in human eosinophils. J Immunol 135:1349, 1985
31. Raible DG, Schulman ES, DiMuzio J, Cardillo R, Post TJ: Mast cell mediators prostaglandin-D2 and histamine activate human eosinophils. J Immunol 148:3536, 1992
32. 2+ and guanine nucleotides. J Immunol 147:1905, 1991
33. Kroegel C, Chilvers ER, Giembycz MA, Challiss RA, Barnes PJ: Platelet activating factor stimulates a rapid accumulation of inositol [1,4,5] triphosphate in guinea-pig eosinophils; relationship to calcium mobilization and degranulation. J Allergy Clin Immunol 88:114, 1991
34. McConkey DJ, Hartzell P, Amador-Perez JF, Orrenius S, Jondal M: Calcium-dependent killing of immature thymocytes by stimulation via the CD3/T cell receptor complex. J Immunol 143:1801, 1989
35. Pizzo P, Zanovello P, Bronte V, Di Virgilio F: Extracellular ATP causes lysis of mouse thymocytes and activates a plasma membrane ion channel. Biochem J 274:139, 1991
36. 2+-mediated mechanisms. Biochem J 304:877, 1994
37. Wakade TD, Palmer KC, McCauley R, Przywara DA, Wakade AR: Adenosine-induced apoptosis in chick embryonic sympathetic neurons: A new physiological role for adenosine. J Physiol 488:123, 1995
38. 3 adenosine receptor with widespread tissue distribution. Mol Pharmacol 44:524, 1993
39. Beaven MA, Ramkumar V, ALI H: Adenosine-A(3) receptors in mast-cells. Trends Pharmacol Sci 15:13, 1994