Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as highly potent and selective human a3 adenosine receptor antagonists

Journal of Medicinal Chemistry

Volumn 42, Issue 22, 1999, Pages 4473-4478

  Baraldi, Pier Giovanni ^a   Cacciari, Barbara ^a   Romagnoli, Romeo ^a   Spalluto, Giampiero ^b   Klotz, Karl Norbert ^c   Leung, Edward ^d   Varani, Katia ^a   Gessi, Stefania ^a   Merighi, Stefania ^a   Borea, Pier Andrea ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d Medco Research Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A3 RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; PYRIMIDINE DERIVATIVE;

BINDING AFFINITY; CHEMICAL REACTION; DRUG ACTIVITY; DRUG POTENCY; LETTER; RECEPTOR AFFINITY; RECEPTOR BINDING; RECEPTOR BLOCKING;

ANIMALS; BINDING, COMPETITIVE; BRAIN; CHO CELLS; CRICETINAE; CYCLIC AMP; HUMANS; PYRAZOLES; PYRIMIDINES; RATS; RECEPTOR, ADENOSINE A3; RECEPTORS, PURINERGIC P1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0033524031     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm991114s     Document Type: Letter

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