The adenosine A3 receptor agonist, N6-(3-iodobenzyl)-adenosine-5′-N-methyluronamide, is protective in two murine models of colitis

European Journal of Pharmacology

Volumn 466, Issue 3, 2003, Pages 323-329

  Mabley, Jon ^a   Soriano, Francisco ^b   Pacher, Pál ^a   Haskó, György ^b   Marton, Anita ^a   Wallace, Rebecca ^a   Salzman, Andrew ^a   Szabó, Csaba ^a,b  

^a INOTEK CORPORATION   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Adenosine; Chemokine; Colitis; Cytokine

Indexed keywords

6 N (3 IODOBENZYL)ADENOSINE 5' N METHYLCARBOXAMIDE; ADENOSINE A3 RECEPTOR; ADENOSINE A3 RECEPTOR AGONIST; AMIDE; CHEMOKINE; CYTOKINE; DEXTRAN SODIUM SULFATE; FREE RADICAL; INTERLEUKIN 10; MALONALDEHYDE; MYELOPEROXIDASE; PROTECTIVE AGENT; SULFATE; UNCLASSIFIED DRUG; ADENOSINE; ADENOSINE RECEPTOR; DEXTRAN SULFATE; DRUG DERIVATIVE; INTERLEUKIN 1; INTERLEUKIN 12; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1; MIP 2 PROTEIN, MOUSE; MIP-2 PROTEIN, MOUSE; N(6) (3 IODOBENZYL) 5' N METHYLCARBOXAMIDOADENOSINE; N(6)-(3-IODOBENZYL)-5'-N-METHYLCARBOXAMIDOADENOSINE; PEROXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; BODY WEIGHT; CELL INFILTRATION; COLITIS; COLON INJURY; CONTROLLED STUDY; DRUG EFFECT; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECTUM HEMORRHAGE; ANIMAL; BAGG ALBINO MOUSE; CHEMICALLY INDUCED DISORDER; COLON; DISEASE MODEL; DOSE RESPONSE; DRUG POTENTIATION; GASTROINTESTINAL HEMORRHAGE; GENETICS; METABOLISM; MOUSE MUTANT; PATHOLOGY; RECTUM DISEASE; WEIGHT REDUCTION;

ADENOSINE; ANIMALS; CHEMOKINES; COLITIS; COLON; DEXTRAN SULFATE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTROINTESTINAL HEMORRHAGE; INTERLEUKIN-1; INTERLEUKIN-12; INTERLEUKIN-6; MACROPHAGE INFLAMMATORY PROTEIN-1; MALE; MALONDIALDEHYDE; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; PEROXIDASE; RECEPTOR, ADENOSINE A3; RECEPTORS, PURINERGIC P1; RECTAL DISEASES; WEIGHT LOSS;

EID: 0037453358     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(03)01570-X     Document Type: Article

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