Activation of murine lung mast cells by the adenosine A3 receptor

Journal of Immunology

Volumn 171, Issue 1, 2003, Pages 338-345

  Zhong, Hongyan ^a   Shlykov, Sergiy G ^a   Molina, Jose G ^a   Sanborn, Barbara M ^a   Jacobson, Marlene A ^b   Tilley, Stephen L ^c   Blackburn, Michael R ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ADENOSINE A2A RECEPTOR; ADENOSINE A2B RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE A3 RECEPTOR AGONIST; ADENOSINE DEAMINASE; ADENOSINE DERIVATIVE; CALCIUM ION; HISTAMINE; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTHMA; CALCIUM CELL LEVEL; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; HISTAMINE RELEASE; IMMUNOFLUORESCENCE; LUNG; MALE; MAST CELL; MAST CELL DEGRANULATION; MEDIATOR RELEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

EID: 0038205888     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.171.1.338     Document Type: Article

References (55)

1. Olah, M. E., and G. L. Stiles. 1995. Adenosine receptor subtypes: characteriza-tion and therapeutic regulation. Annu. Rev. Pharmacol. Toxicol. 35:581.
2. Belardinelli, L., J. Linden, and R. M. Berne. 1989. The cardiac effects of adenosine. Prog. Cardiovasc. Dis. 32:73.
3. Fredholm, B. B., and T. V. Dunwiddie. 1988. How does adenosine inhibit transmitter release? Trends Pharmacol. Sci. 9:130.
4. Churchill, P. C. 1982. Renal effects of 2-chloroadenosine and their antagonism by aminophylline in anesthetized rats. J. Phannacol. Exp. Ther. 222:319.
5. Huang, S., S. Apasov, M. Koshiba, and M. Sitkovsky. 1997. Role of A2a extra-cellular adenosine receptor-mediated signaling in adenosine-mediated inhibition of T-cell activation and expansion. Blood 90:1600.
6. Jacobson, M. A., and T. R. Bai. 1997. The Role of Adenosine in Asthma. In Purinergic Approaches in Experimental Therapeutics. K. A. Jacobson and M. F. Jarvis, eds. Wiley-Liss, Danvers, p. 315.
7. Fozard, J. R., and J. P. Hannon. 1999. Adenosine receptor ligands: potential as therapeutic agents in asthma and COPD. Pulm. Pharmacol. Ther. 12:111.
8. Driver, A. G., C. A. Kukoly, S. Ali, and S. J. Mustafa. 1993. Adenosine in bronchoalveolar lavage fluid in asthma. Am. Rev. Respir. Dis. 148:91.
9. Walker, B. A., M. A. Jacobson, D. A. Knight, C. A. Salvatore, T. Weir, D. Zhou, and T. R. Bai. 1997. Adenosine A3 receptor expression and function in eosino-phils. Am. J. Respir. Cell Mol. Biol. 16:531.
10. Cushley, M. J., A. E. Tattersfield, and S. T. Holgate. 1984. Adenosine-induced bronchoconstriction in asthma: antagonism by inhaled theophylline. Am. Rev. Respir. Dis. 129:380.
11. Oosterhoff, Y., J. W. de Jong, M. A. Jansen, G. H. Koeter, and D. S. Postma. 1993. Airway responsiveness to adenosine 5′-monophosphate in chronic obstructive pulmonary disease is determined by smoking. Am. Rev. Respir. Dis. 147:553.
12. Marquardt, D. L., C. W. Parker, and T. J. Sullivan. 1978. Potentiation of mast cell mediator release by adenosine. J. Immunol. 120:871.
13. Cronstein, B. N. 1997. Adenosine regulation of neutrophil function and inhibition of inflammation via adenosine receptors. In Purinergic Approaches in Experimental Therapeutics. K. A. Jacobson and M. F. Jarvis, eds. Wiley-Liss, New York, p. 285.
14. Eppell, B. A., A. M. Newell, and E. J. Brown. 1989. Adenosine receptors are expressed during differentiation of monocytes to macrophages in vitro: implications for regulation of phagocytosis. J. Immunol. 143:4141.
15. Hasko, G., C. Szabo, Z. H. Nemeth, V. Kvetan, S. M. Pastores, and E. S. Vizi. 1996. Adenosine receptor agonists differentially regulate IL-10, TNF-α, and nitric oxide production in RAW 264.7 macrophages and in endotoxemic mice. J. Immunol. 157:4634.
16. Johnson, H. G., and M. L. McNee. 1985. Adenosine-induced secretion in the canine trachea: modification by methylxanthines and adenosine derivatives. Br. J. Pharmacol. 86:63.
17. Krzanowski, J. J., A. Urdaneta-Bohorquez, J. B. Polson, Y. Sakamoto, and A. Szentivanyi. 1987. Effects of adenosine and theophylline on canine tracheal smooth muscle tone. Arch. Int. Phannacodyn. Ther. 287:224.
18. Shimizu, Y., and L. B. Schwartz. 1997. Mast Cell Involvement in Asthma. Lippincot-Raven, Philadelphia.
19. Grashoff, W. F., J. K. Sont, P. J. Sterk, P. S. Hiemstra, W. I. de Boer, J. Stolk, J. Han, and J. M. van Krieken. 1997. Chronic obstructive pulmonary disease: role of bronchiolar mast cells and macrophages. Am. J. Pathol. 151:1785.
20. Marquardt, D. L., L. L. Walker, and S. Heinemann. 1994. Cloning of two adenosine receptor subtypes from mouse bone marrow-derived mast cells. J. Immunol. 152:4508.
21. Ramkumar, V., G. L. Stiles, M. A. Beaven, and H. Ali. 1993. The A3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells. J. Biol. Chem. 268:16887.
22. Hughes, P. J., S. T. Holgate, and M. K. Church. 1984. Adenosine inhibits and potentiates IgE-dependent histamine release from human lung mast cells by an A2-purinoceptor mediated mechanism. Biochem. Pharmacol. 33:3847.
23. Doyle, M. P., J. Linden, and B. R. Duling. 1994. Nucleoside-induced arteriolar constriction: a mast cell-dependent response. Am. J. Physiol. 266:H2042.
24. Hannon, J. P., H. J. Pfannkuche, and J. R. Fozard. 1995. A role for mast cells in adenosine A3 receptor-mediated hypotension in the rat. Br. J. Pharmacol. 115:945.
25. Zhong, H., J. L. Chunn, J. B. Volmer, J. R. Fozard, and M. R. Blackburn. 2001. Adenosine-mediated mast cell degranulation in adenosine deaminase-deficient mice. J. Pharmacol. Exp. Ther. 298:433.
26. Feoktistov, I., and I. Biaggioni. 1995. Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells: an enprofylline-sensitive mechanism with implications for asthma. J. Clin. Invest. 96:1979.
27. 3 receptors on mast cells. J. Clin. Invest. 105:361.
28. Laffargue, M., R. Calvez, P. Finan, A. Trifilieff, M. Barbier, F. Altruda, E. Hirsch, and M. P. Wymann. 2002. Phosphoinositide 3-kinase γ is an essential amplifier of mast cell function. Immunity 16:441.
29. Blackburn, M. R., S. K. Datta, and R. E. Kellems. 1998. Adenosine deaminasedeficient mice generated using a two-stage genetic engineering strategy exhibit a combined immunodeficiency. J. Biol. Chem. 273:5093.
30. Wakamiya, M., M. R. Blackburn, R. Jurecic, M. J. McArthur, R. S. Geske, J. Cartwright, Jr., K. Mitani, S. Vaishnav, J. W. Belmont, R. E. Kellems, et. al. 1995. Disruption of the adenosine deaminase gene causes hepatocellular impairment and perinatal lethality in mice. Proc. Natl. Acad. Sci. USA 92:3673.
31. 3 adenosine receptor gene in mice and its effect on stimulated inflammatory cells. J. Biol. Chem. 275:4429.
32. Lukacs, N. W., S. L. Kunkel, R. M. Strieter, H. L. Evanoff, R. G. Kunkel, M. L. Key, and D. D. Taub. 1996. The role of stem cell factor (c-kit ligand) and inflammatory cytokines in pulmonary mast cell activation. Blood 87:2262.
33. Barrett, K. E., E. F. Szucs, and D. D. Metcalfe. 1986. Mast cell heterogeneity in higher animals: a comparison of the properties of autologous lung and intestinal mast cells from nonhuman primates. J. Immunol. 137:2001.
34. Chunn, J. L., H. W. Young, S. K. Banerjee, G. N. Colasurdo, and M. R. Blackburn. 2001. Adenosine-dependent airway inflammation and hyperresponsiveness in partially adenosine deaminase-deficient mice. J. Immunol. 167: 4676.
35. Depre, C., M. E. Young, J. Ying, H. S. Ahuja, Q. Han, N. Garza, P. J. Davies, and H. Taegtmeyer. 2000. Streptozotocin-induced changes in cardiac gene expression in the absence of severe contractile dysfunction. J. Mol. Cell. Cardiol. 32:985.
36. Blackburn, M. R., M. Aldrich, J. B. Volmer, W. Chen, H. Zhong, S. Kelly, M. S. Hershfield, S. K. Datta, and R. E. Kellems. 2000. The use of enzyme therapy to regulate the metabolic and phenotypic consequences of adenosine deaminase deficiency in mice: differential impact on pulmonary and immunologic abnormalities. J. Biol. Chem. 275:32114.
37. Scharenberg, A. M., O. El-Hillal, D. A. Fruman, L. O. Beitz, Z. Li, S. Lin, I. Gout, L. C. Cantley, D. J. Rawlings, and J. P. Kinet. 1998. Phosphatidylinositol-3,4,5-trisphosphate (PtdIns-3,4,5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals. EMBO J. 17:1961.
38. Forsythe, P., L. P. McGarvey, L. G. Heaney, J. MacMahon, and M. Ennis. 1999. Adenosine induces histamine release from human bronchoalveolar lavage mast cells. Clin. Sci. 96:349.
39. Forsythe, P., and M. Ennis. 1999. Adenosine, mast cells and asthma. Inflamm. Res. 48:301.
40. Blackburn, M. R., J. B. Volmer, J. L. Thrasher, H. Zhong, J. R. Crosby, J. J. Lee, and R. E. Kellems. 2000. Metabolic consequences of adenosine deaminase deficiency in mice are associated with defects in alveogenesis, pulmonary inflammation, and airway obstruction. J. Exp. Med. 192:159.
41. Banerjee, S. K., H. W. Young, J. B. Volmer, and M. R. Blackburn. 2002. Gene expression profiling in inflammatory airway disease associated with elevated adenosine. Am. J. Physiol. 282:L169.
42. -/- mice: the role of mast cells. J. Immunol. 163:2160.
43. q in human embryonic kidney 293 cells and HMC-1 mast cells. Mol. Pharmacol. 56:705.
44. i3 proteins by basic secretagogues induces exocytosis through phospholipase Cβ and arachidonate release through phospholipase Cγ mast cells. J. Immunol. 167:4805.
45. Hawes, B. E., L. M. Luttrell, T. van Biesen, and R. J. Lefkowitz. 1996. Phosphatidylinositol 3-kinase is an early intermediate in the Gβγ-mediated mitogen-activated protein kinase signaling pathway. J. Biol. Chem. 271:12133.
46. Yano, H., S. Nakanishi, K. Kimura, N. Hanai, Y. Saitoh, Y. Fukui, Y. Nonomura, and Y. Matsuda. 1993. Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells. J. Biol. Chem. 268:25846.
47. Hirsch, E., V. L. Katanaev, C. Garlanda, O. Azzolino, L. Pirola, L. Silengo, S. Sozzani, A. Mantovani, F. Altruda, and M. P. Wymann. 2000. Central role for G protein-coupled phosphoinositide 3-kinase γ in inflammation. Science 287: 1049.
48. 2+ entry mechanism. J. Biol. Chem. 276:14814.
49. Polosa, R., and S. T. Holgate. 1997. Adenosine bronchoprovocation: a promising marker of allergic inflammation in asthma? Thorax 52:919.
50. Polosa, R., S. Rorke, and S. T. Holgate. 2002. Evolving concepts on the value of adenosine hyperresponsiveness in asthma and chronic obstructive pulmonary disease. Thorax 57:649.
51. Phillips, G. D., V. L. Scott, R. Richards, and S. T. Holgate. 1989. Effect of nedocromil sodium and sodium cromoglycate against bronchoconstriction induced by inhaled adenosine 5′-monophosphate. Eur. Respir. J. 2:210.
52. Phillips, G. D., R. Polosa, and S. T. Holgate. 1989. The effect of histamine-H1 receptor antagonism with terfenadine on concentration-related AMP-induced bronchoconstriction in asthma. Clin. Exp. Allergy 19:405.
53. Van Schoor, J., G. F. Joos, J. C. Kips, J. F. Drajesk, P. J. Carpentier, and R. A. Pauwels. 1997. The effect of ABT-761, a novel 5-lipoxygenase inhibitor, on exercise- and adenosine-induced bronchoconstriction in asthmatic subjects. Am. J. Respir. Crit. Care Med. 155:875.
54. Tilley, S. L., M. Tsai, C. M. Williams, Z.-S. Wang, C. J. Erikson, S. J. Galli, and B. H. Koller. 2003. Identification of A3 receptor- and mast cell-dependent and -independent components of adenosine-mediated airway responsiveness in mice. J. Immunol. 171:331.
55. Auchampach, J. A., X. Jin, T. C. Wan, G. H. Caughey, and J. Linden. 1997. Canine mast cell adenosine receptors: cloning and expression of the A3 receptor and evidence that degranulation is mediated by the A2B receptor. Mol. Pharmacol. 52:846.