Targeted deletion of adenosine A3 receptors augments adenosine-induced coronary flow in isolated mouse heart

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 282, Issue 6 51-6, 2002, Pages

  Hassan Talukder, M A ^a   Ray Morrison, R ^b   Jacobson, Marlene A ^c   Jacobson, Kenneth A ^a   Ledent, Catherine ^d   Jamal Mustafa, S ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^d UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

A2A receptor knockout mice; Coronary vasodilation; Knockout mice

Indexed keywords

2 CHLORO N 6 (3 IODOBENZYL)ADENOSINE 5' N METHYLURONAMIDE; 2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A2A RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE A3 RECEPTOR AGONIST; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; GENE DELETION; HEART; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR BLOCKING; RECEPTOR INTRINSIC ACTIVITY; VASODILATATION;

EID: 0036083280     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00964.2001     Document Type: Article

References (37)

1. Adenosine receptormediated relaxation of porcine coronary artery in presence and absence of endothelium
2. 2A adenosine receptor mediates coronary vasodilation
3. 2B adenosine receptor in NIH 3T3 fibroblasts
4. 3 adenosine receptors improves tolerance to ischemia-reperfusion injury in mouse myocardium
5. 2B receptors
6. Nomenclature and classification of purinoceptors
7. 3 receptor confers resistance to myocardial ischemic injury and does not prevent early preconditioning
8. Functional characterization of three adenosine receptor types
9. 1 adenosine receptors
10. 1 receptor overexpression
11. Adenosine, the heart, and coronary circulation
12. 3 receptors: Novel ligands and paradoxical effects
13. 3 adenosine receptor-selective antagonists
14. 2B receptors
15. 3 receptor subtype
16. 3 receptor agonists IB-MECA and Cl-IB-MECA
17. 2A receptor
18. Involvement of functional antagonism in the effects of adenosine antagonists and L-NAME in the rat isolated heart
19. 2 receptor agonists CGS 21680 and CGS 22492 in human vasculature
20. 2B receptors
21. Role of adenosine in the heart and circulation
22. Adenosine receptor antagonist: Structures and potential therapeutic applications
23. Coronary vasodilation by adenosine: Receptor subtypes and mechanism(s) of action
24. Evidence suggesting an Ra-type adenosine receptor in bovine coronary arteries
25. 2A adenosine receptor antagonist
26. Comparison of CGS 15943, ZM 241385 and SCH 58261 as antagonists at human adenosine receptors
27. 2 adenosine receptor in human coronary arteries
28. 3 adenosine receptor gene in mice and its effect on stimulated inflammatory cells
29. Hemodynamic effects and histamine release elicited by the selective adenosine A3 receptor agonist 2-Cl-IB-MECA in conscious rats
30. 3 adenosine receptor
31. 2B receptors in vasodilation of rat pial artery and cerebral blood flow autoregulation
32. Adenosine and adenosine receptors in the cardiovascular system: Biochemistry, physiology, and pharmacology
33. The isolated blood and perfusion fluid perfused heart
34. Comparison of the vascular effects of adenosine in isolated mouse heart and aorta
35. 3-subtype adenosine receptor in highly expressed in rat vascular smooth muscle cells: Its role in attenuating adenosine-induced increas in cAMP
36. 3 adenosine receptor in determining tissue levels of cAMP and blood pressure: Studies in knock-out mice
37. 2A adenosine receptor antagonist