Isoquinoline and quinazoline urea analogues as antagonists for the human-adenosine A3 receptor

Journal of Medicinal Chemistry

Volumn 43, Issue 11, 2000, Pages 2227-2238

  Van Muijlwijk Koezen, Jacqueline E ^b   Timmerman, Henk ^b   Van Der Goot, Henk ^b   Menge, Wiro M P B ^b   Von Drabbe Künzel, Jacobien Frijtag ^a,b   De Groote, Miriam ^a,b   Ijzerman, Adriaan P ^a,b  

^a LEIDEN UNIVERSITY   (Netherlands)

^b VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE A3 RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; BENZENE; CYCLIC AMP; ISOQUINOLINE DERIVATIVE; N (2 METHOXYPHENYL) N' [2 (3 PYRIDYL)QUINAZOLIN 4 YL]UREA; PHENYL GROUP; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG; VUF 5574; VUF 8504;

ARTICLE; DRUG POTENCY; HUMAN; MOLECULAR MODEL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RECEPTOR AFFINITY;

ANIMALS; BINDING SITES; CELLS, CULTURED; CEREBRAL CORTEX; CHO CELLS; CRICETINAE; HUMANS; ISOQUINOLINES; MODELS, MOLECULAR; QUINAZOLINES; RATS; RECEPTOR, ADENOSINE A3; RECEPTORS, PURINERGIC P1; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034213365     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm000002u     Document Type: Article

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