Adenosine A3 receptor activation produces nociceptive behaviour and edema by release of histamine and 5-hydroxytryptamine

European Journal of Pharmacology

Volumn 333, Issue 1, 1997, Pages 1-7

  Sawynok, Jana ^a   Zarrindast, Mohammad Reza ^a   Reid, Allison R ^a   Doak, Greg J ^a  

^a DALHOUSIE UNIVERSITY   (Canada)

Author keywords

5 HT (5 hydroxytryptamine, serotonin); Adenosine A3 receptor; Histamine; Pain

Indexed keywords

1 METHYL 3 INDOLECARBOXYLIC ACID [1 [2 (METHYLSULFONYLAMINO)ETHYL] 4 PIPERIDINYLMETHYL] ESTER; ADENOSINE A3 RECEPTOR; ADENOSINE RECEPTOR STIMULATING AGENT; FORMALDEHYDE; KETANSERIN; MEPYRAMINE; PROPRANOLOL; TROPISETRON; 3,7 DIMETHYL 1 PROPARGYLXANTHINE; 3,7-DIMETHYL-1-PROPARGYLXANTHINE; 8 CYCLOPENTYLTHEOPHYLLINE; 8-CYCLOPENTYL-1,3-DIMETHYLXANTHINE; ADENOSINE RECEPTOR; DRUG DERIVATIVE; SEROTONIN; THEOBROMINE; THEOPHYLLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; CONTROLLED STUDY; EDEMA; MALE; NONHUMAN; PAIN; PLETHYSMOGRAPHY; PRIORITY JOURNAL; RAT; SUBCUTANEOUS DRUG ADMINISTRATION; ANIMAL; ANIMAL BEHAVIOR; BODY TEMPERATURE; CHEMICALLY INDUCED DISORDER; DRUG EFFECT; HISTAMINE RELEASE; METABOLISM; PATHOLOGY; PSYCHOLOGICAL ASPECT; SPRAGUE DAWLEY RAT;

ANIMALS; BEHAVIOR, ANIMAL; BODY TEMPERATURE; EDEMA; HISTAMINE RELEASE; INJECTIONS, SUBCUTANEOUS; MALE; PAIN; PLETHYSMOGRAPHY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P1; SEROTONIN; THEOBROMINE; THEOPHYLLINE;

EID: 0030610258     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01110-2     Document Type: Article

References (40)

1. 2 receptors potentiates pain produced by inflammatory mediators. Neuropharmacology. 35:1996;99-110.
2. Amann R., Schuligoi R., Lanz I., Donnerer J. Histamine-induced edema in the rat paw - Effect of capsaicin denervation and a CGRP receptor antagonist. Eur. J. Pharmacol. 279:1995;227-231.
3. 3H ]NECA in rat striatal membranes Mol. Pharmacol. 29:1986;331-346.
4. Church M.K., Hughes P.J., Vardey C.J. Studies on the receptor mediating cyclic AMP-independent enhancement by adenosine IgE-dependent mediator release from rat mast cells. Br. J. Pharmacol. 87:1986;233-242.
5. Cronstein B.N. Adenosine, an endogenous anti-inflammatory agent. J. Appl. Physiol. 76:1994;5-13.
6. Dimitriadou V., Buzzi M.G., Moskowitz M.A., Theoharides T.C. Trigeminal sensory fiber stimulation induces morphological changes reflecting secretion in rat dura mater mast cells. Neuroscience. 44:1991;97-112.
7. Doak G.J., Sawynok J. Complex role of peripheral adenosine in the genesis of the response to subcutaneous formalin in the rat. Eur. J. Pharmacol. 281:1995;311-318.
8. Doak, G.J., Sawynok, J., 1997. Formalin-induced nociceptive behavior and edema: Involvement of multiple peripheral 5-hydroxytryptamine receptor subtypes. Neuroscience, in press.
9. Dray A. Inflammatory mediators of pain. Br. J. Anaesth. 75:1995;125-131.
10. 3 receptor activation in rats. Eur. J. Pharmacol. 298:1996;293-297.
11. 3-selective adenosine agonists. J. Med. Chem. 37:1994;636-646.
12. 1 receptors. J. Am. Coll. Cardiol. 25:1995;251-257.
13. Green P.G., Basbaum A.I., Helms C., Levine J.D. Purinergic regulation of bradykinin-induced plasma extravasation and adjuvant-induced arthritis in the rat. Proc. Natl. Acad. Sci. USA. 88:1991;4162-4165.
14. Handwerker, H.O., Reeh, P.W., 1991. Pain and inflammation. In: Proceedings of the VIth World Congress on Pain. Elsevier, Amsterdam, pp. 59-70.
15. 3 receptor-mediated hypotension in the rat. Br. J. Pharmacol. 115:1995;945-952.
16. Hill S.J. Distribution, properties and functional characteristics of three classes of histamine receptor. Pharmacol. Rev. 42:1990;45-83.
17. Hong Y., Abbott F.V. Behavioral effects of intraplantar injection of inflammatory mediators in the rat. Neuroscience. 63:1994;827-836.
18. 3-adenosine receptors in mediation of behavioral depressant effects. FEBS. 336:1993;57-60.
19. Jensen K., Tuxen C., Pedersen-Bjergaard U., Jansen I., Edvinsson L., Olesen J. Pain, wheal and flare in human forearm skin induced by bradykinin and 5-hydroxytryptamine. Peptides. 11:1990;1133-1138.
20. Karlsten R., Gordh T., Post C. Local antinociceptive and hyperalgesic effects in the formalin test after peripheral administration of adenosine analogues in mice. Pharmacol. Toxicol. 70:1992;434-438.
21. Keele, C.A., Armstrong, D., 1964. Histamine. In: Substances Producing Pain and Itch. Edward Arnold, London, pp. 124-151.
22. Levine, J., Taiwo, Y., 1994. Inflammatory pain. In: Wall, P.D., Melzack, R. (Eds.), Textbook of Pain, 3rd ed. Churchill Livingstone, London, pp. 45-56.
23. 3 receptors: Pharmacological properties, species differences and receptor functions. Trends Pharmacol. Sci. 15:1994;298-306.
24. Maling H.M., Webster M.E., Williams M.A., Saul W., Anderson W. Inflammation induced by histamine, serotonin, bradykinin and compound 48/80 in the rat: Antagonists and mechanisms of action. J. Pharmacol. Exp. Ther. 191:1974;300-310.
25. Ninkovic M., Hunt S.P. Opiate and histamine H1 receptors are present on some substance P-containing dorsal root ganglion cells. Neurosci. Lett. 53:1985;133-137.
26. 1-receptors in the primate sensory ganglia and spinal cord. Brain Res. 241:1982;197-206.
27. Pappagallo M., Gaspardone A., Tomai F., Iamele M., Crea F., Gioffrè P.A. Analgesic effect of bamiphylline on pain induced by intradermal injection of adenosine. Pain. 53:1993;199-204.
28. Pierce P.A., Xie G.X., Levine J.D., Peroutka S.J. 5-Hydroxytryptamine receptor subtype messenger RNAs in rat peripheral sensory and sympathetic ganglia: A polymerase chain reaction study. Neuroscience. 70:1996;553-559.
29. 3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells. J. Biol. Chem. 268:1993;16887-16890.
30. Saria A., Martling C.R., Yan Z., Theodorsson-Norheim E., Gamse R., Lundberg J.M. Release of multiple tachykinins from capsaicin-sensitive sensory nerves in the lung by bradykinin, histamine, dimethylphenyl piperazinium and vagal nerve stimulation. Am. Rev. Respir. Dis. 137:1988;1330-1335.
31. Sawynok, J., 1997. Purines and nociception. In: Jacobson, K., Jarvis, M.F. (Eds.), Purinergic Approaches in Experimental Therapeutics. Wiley and Sons, New York, in press.
32. Shibata M., Ohkubo T., Takahashi H., Inoki R. Modified formalin test: Characteristic biphasic pain response. Pain. 38:1989;347-352.
33. Simone D.A., Ngeow J.Y.F., Whitehouse J., Becerra-Cabal L., Putterman G.J., LaMotte R.H. The magnitude and duration of itch produced by intracutaneous injections of histamine. Somatosens. Res. 5:1987;81-92.
34. Sufka K.J., Schomburg F.M., Giordano J. Receptor mediation of 5-HT-induced inflammation and nociception in rats. Pharmacol. Biochem. Behav. 41:1991;53-56.
35. Taiwo Y.O., Levine J.D. Direct cutaneous hyperalgesia induced by adenosine. Neuroscience. 38:1990;757-762.
36. Tani E., Shiosaka S., Sato M., Ishikawa T., Tohyama M. Histamine acts directly on calcitonin gene-related peptide- and substance P-containing trigeminal ganglion neurons as assessed by calcium influx and immunocytochemistry. Neurosci. Lett. 115:1990;171-176.
37. Tjølsen A., Berge O.G., Hunskaar S., Rosland J.H., Hole K. The formalin test: An evaluation of the method. Pain. 51:1992;5-17.
38. Treede R.D., Meyer R.A., Raja S.N., Campbell J.N. Peripheral and central mechanisms of cutaneous hyperalgesia. Prog. Neurobiol. 38:1992;397-421.
39. 2 adenosine receptors. Life Sci. 39:1986;743-750.
40. 3 receptor agonist 2-Cl-IB-MECA in conscious rats. Eur. J. Pharmacol. 308:1996;311-314.