Conformational changes in the G protein Gs induced by the β 2 adrenergic receptor

Nature

Volumn 477, Issue 7366, 2011, Pages 611-617

  Chung, Ka Young ^a   Rasmussen, Sǒren G F ^a,b   Liu, Tong ^c   Li, Sheng ^c   Devree, Brian T ^d   Chae, Pil Seok ^e,f   Calinski, Diane ^d   Kobilka, Brian K ^a   Woods Jr , Virgil L ^c   Sunahara, Roger K ^d  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF WISCONSIN MADISON   (United States)

^f Hanyang University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; DEUTERIUM; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HYDROGEN; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

CHEMICAL BINDING; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DEUTERIUM; ELECTRON PROBE ANALYSIS; HYDROGEN; MASS SPECTROMETRY; PROTEIN; SIGNALING; X-RAY SPECTROSCOPY;

ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; ELECTRON MICROSCOPY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN CONFORMATION; RECEPTOR BINDING; X RAY CRYSTALLOGRAPHY;

ADRENERGIC BETA-2 RECEPTOR AGONISTS; ANIMALS; BIOCATALYSIS; CATALYTIC DOMAIN; CATTLE; CRYSTALLOGRAPHY, X-RAY; DEUTERIUM EXCHANGE MEASUREMENT; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; GUANOSINE DIPHOSPHATE; GUANOSINE TRIPHOSPHATE; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, ADRENERGIC, BETA-2;

BOVINAE;

EID: 80053357815     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature10488     Document Type: Article

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