KF26777 (2-(4-bromophenyl)-7,8-dihydro-4-propyl-1H-imidazo[2,1-i]purin-5(4H)-one dihydrochloride), a new potent and selective adenosine A3 receptor antagonist

European Journal of Pharmacology

Volumn 444, Issue 3, 2002, Pages 133-141

  Saki, Mayumi ^a   Tsumuki, Hiroshi ^a   Nonaka, Hiromi ^a   Shimada, Junichi ^a   Ichimura, Michio ^a  

^a KYOWA HAKKO KOGYO CO LTD   (Japan)

Author keywords

Adenosine A3 receptor; Binding assay; Ca2+; Guanine nucleotide; KF26777 (2 (4 bromophenyl) 7,8 dihydro 4 propyl 1H imidazo 2,1 i purin 5(4H) one dihydrochloride)

Indexed keywords

2 (4 BROMOPHENYL) 7,8 DIHYDRO 4 PROPYL 1H IMIDAZO[2,1 I]PURIN 5(4H) ONE; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A2B RECEPTOR; ADENOSINE A3 RECEPTOR; ADENOSINE A3 RECEPTOR ANTAGONIST; ADENOSINE DERIVATIVE; CALCIUM ION; DEXAMETHASONE; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); KF 26777; N 6 (4 AMINO 3 IODOBENZYL)ADENOSINE 5' N METHYLURONAMIDE; UNCLASSIFIED DRUG; ADENOSINE RECEPTOR; PURINE DERIVATIVE;

ARTICLE; CALCIUM CELL LEVEL; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENCY; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; RECEPTOR UPREGULATION; ANIMAL; CELL LINE; CHO CELL; DRUG ANTAGONISM; HAMSTER; METABOLISM;

ANIMAL; CELL LINE; CHO CELLS; HAMSTERS; HL-60 CELLS; HUMAN; PURINES; RECEPTORS, PURINERGIC P1; ANIMALS; CRICETINAE; HUMANS; RECEPTOR, ADENOSINE A3;

EID: 0037204734     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)01662-X     Document Type: Article

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