Adenosine-A 3 receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes

EMBO Reports

Volumn 14, Issue 8, 2013, Pages 726-732

  Corriden, Ross ^a   Self, Tim ^a   Akong Moore, Kathryn ^b   Nizet, Victor ^b,c   Kellam, Barrie ^a   Briddon, Stephen J ^a   Hill, Stephen J ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b Department of Pediatrics ^*  (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

adenosine receptors; host pathogen interactions; neutrophils

Indexed keywords

ADENOSINE A3 RECEPTOR; ADENOSINE A3 RECEPTOR AGONIST; ADENOSINE A3 RECEPTOR ANTAGONIST; LIGAND; ADENOSINE RECEPTOR BLOCKING AGENT;

ARTICLE; BACTERIUM; CELL FUNCTION; CELL MEMBRANE; CELL MIGRATION; CELL STRUCTURE; CELLS; CHEMOTAXIS; CONTROLLED STUDY; CYTONEME; FLUORESCENCE; HUMAN; HUMAN CELL; NEUTROPHIL; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN FUNCTION; CELL STRAIN HL 60; DRUG EFFECT; ESCHERICHIA COLI; HOST PATHOGEN INTERACTION; MEMBRANE STRUCTURE; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; PROTEIN BINDING; ULTRASTRUCTURE;

BACTERIA (MICROORGANISMS);

CELL MEMBRANE STRUCTURES; ESCHERICHIA COLI; HL-60 CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; LIGANDS; NEUTROPHILS; PHAGOCYTOSIS; PROTEIN BINDING; PURINERGIC P1 RECEPTOR ANTAGONISTS; RECEPTOR, ADENOSINE A3;

EID: 84881480493     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2013.89     Document Type: Article

References (25)

1. Junger WG (2011) Immune cell regulation by autocrine purinergic signalling. Nat Rev Immunol 11: 201-212
2. Elliott MR et al (2009) Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature 461: 282-286
3. Chen Y, Corriden R, Inoue Y, Yip L, Hashiguchi N, Zinkernagel A, Nizet V, Insel PA, Junger WG (2006) ATP release guides neutrophil chemotaxis via P2Y2 and A3 receptors. Science 314: 1792-1795 (Pubitemid 44969094)
4. Kronlage M et al (2010) Autocrine purinergic receptor signaling is essential for macrophage chemotaxis. Sci Signal 3: ra55
5. McDonald B, Pittman K, Menezes GB, Hirota SA, Slaba I, Waterhouse CCM, Beck PL, Muruve DA, Kubes P (2010) Intravascular danger signals guide neutrophils to sites of sterile inflammation. Science 330: 362-366
6. Corriden R, Insel PA (2010) Basal release of ATP: an autocrine-paracrine mechanism for cell regulation. Sci Signal 3: re1
7. Corriden R, Chen Y, Inoue Y, Beldi G, Robson SC, Insel PA, Junger WG (2008) Ecto-nucleoside triphosphate diphosphohydrolase 1 (E-NTPDase1/CD39) regulates neutrophil chemotaxis by hydrolyzing released ATP to adenosine. J Biol Chem 283: 28480-28486
8. Inoue Y, Chen Y, Hirsh MI, Yip L, Junger WG (2008) A3 and P2Y2 receptors control the recruitment of neutrophils to the lungs in a mouse model of sepsis. Shock 30: 173-177
9. van der Hoeven D, Wan TC, Auchampach JA (2008) Activation of the A3 adenosine receptor suppresses superoxide production and chemotaxis of mouse bone marrow neutrophils. Mol Pharmacol 74: 685-696
10. Stoddart Leigh A, Vernall Andrea J, Denman Jessica L, Briddon Stephen J, Kellam B, Hill Stephen J (2012) Fragment screening at adenosine-A3 receptors in living cells using a fluorescence-based binding assay. Chem Biol 19: 1105-1115
11. Galkina SI, Molotkovsky JG, Ullrich V, Sud'ina GF (2005) Scanning electron microscopy study of neutrophil membrane tubulovesicular extensions (cytonemes) and their role in anchoring, aggregation and phagocytosis. The effect of nitric oxide. Exp Cell Res 304: 620-629 (Pubitemid 40321137)
12. Galkina SI, Romanova JM, Stadnichuk VI, Molotkovsky JG, Sud'ina GF, Klein T (2009) Nitric oxide-induced membrane tubulovesicular extensions (cytonemes) of human neutrophils catch and hold Salmonella enterica serovar Typhimurium at a distance from the cell surface. FEMS Immunol Med Microbiol 56: 162-171
13. Pospieszalska MK, Ley K (2009) Dynamics of microvillus extension and tether formation in rolling leukocytes. Cell Mol Bioeng 2: 207-217
14. Sundd P, Gutierrez E, Koltsova EK, Kuwano Y, Fukuda S, Pospieszalska MK, Groisman A, Ley K (2012) 'Slings' enable neutrophil rolling at high shear. Nature 488: 399-403
15. Jacobson KA (1998) Adenosine A3 receptors: novel ligands and paradoxical effects. Trends Pharmacol Sci 19: 184-191 (Pubitemid 28255405)
16. Baraldi PG, Borea PA (2000) New potent and selective human adenosine A3 receptor antagonists. Trends Pharmacol Sci 21: 456-459
17. Vonna L, Wiedemann A, Aepfelbacher M, Sackmann E (2007) Micromechanics of filopodia mediated capture of pathogens by macrophages. Eur Biophys J 36: 145-151 (Pubitemid 46175653)
18. Romero S, Grompone G, Carayol N, Mounier J, Guadagnini S, Prevost M-C, Sansonetti PJ, Van Nhieu GT (2011) ATP-mediated Erk1/2 activation stimulates bacterial capture by filopodia, which precedes shigella invasion of epithelial cells. Cell Host Microbe 9: 508-519
19. Walz A, Odenbreit S, Mahdavi J, Boren T, Ruhl S (2005) Identification and characterization of binding properties of Helicobacter pylori by glycoconjugate arrays. Glycobiology 15: 700-708 (Pubitemid 41417988)
20. Romero S, Quatela A, Bornschlögl T, Guadagnini S, Bassereau P, Tran Van Nhieu G (2012) Filopodium retraction is controlled by adhesion to its tip. J Cell Sci 125: 4999-5004
21. Brinkmann V, Reichard U, Goosmann C, Fauler B, Uhlemann Y, Weiss DS, Weinrauch Y, Zychlinsky A (2004) Neutrophil extracellular traps kill bacteria. Science 303: 1532-1535 (Pubitemid 38314426)
22. Wang X, Veruki ML, Bukoreshtliev NV, Hartveit E, Gerdes H-H (2010) Animal cells connected by nanotubes can be electrically coupled through interposed gap-junction channels. Proc Natl Acad Sci USA 107: 17194-17199
23. Lazarowski E (2012) Vesicular and conductive mechanisms of nucleotide release. Purinergic Signal 8: 359-373
24. Van Nhieu GT, Clair C, Bruzzone R, Mesnil M, Sansonetti P, Combettes L (2003) Connexin-dependent inter-cellular communication increases invasion and dissemination of Shigella in epithelial cells. Nat Cell Biol 5: 720-726 (Pubitemid 36986779)
25. Eltzschig HK, Eckle T, Mager A, Küper N, Karcher C, Weissmüller T, Boengler K, Schulz R, Robson SC, Colgan SP (2006) ATP release from activated neutrophils occurs via connexin 43 and modulates adenosine-dependent endothelial cell function. Circ Res 99: 1100-1108 (Pubitemid 44729934)