Melatonin regulates aging and neurodegeneration through energy metabolism, epigenetics, autophagy and circadian rhythm pathways

International Journal of Molecular Sciences

Volumn 15, Issue 9, 2014, Pages 16848-16884

  Jenwitheesuk, Anorut ^a   Nopparat, Chutikorn ^a   Mukda, Sujira ^a   Wongchitrat, Prapimpun ^b   Govitrapong, Piyarat ^a,b  

^a MAHIDOL UNIVERSITY   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Autophagy; Brain aging; Circadian rhythm; Energy metabolism; Epigenetics; Melatonin; Neurodegeneration; Sirtuins

Indexed keywords

CYCLOSPORIN; FORKHEAD TRANSCRIPTION FACTOR; HUNTINGTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; MAMMALIAN TARGET OF RAPAMYCIN; MELATONIN; METHAMPHETAMINE; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; PER1 PROTEIN; PER2 PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BMAL1; PROTEIN KINASE B; RHEB PROTEIN; SIRTUIN; SIRTUIN 1; SOMATOMEDIN C; TRANSCRIPTION FACTOR CLOCK;

AGING; AUTOPHAGY; CALORIC RESTRICTION; CIRCADIAN RHYTHM; DNA METHYLATION; ENERGY METABOLISM; EPIGENETICS; GENE; GENE EXPRESSION; HUMAN; LONG TERM POTENTIATION; LONGEVITY; MACROAUTOPHAGY; MEMORY; NERVE DEGENERATION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PHOSPHORYLATION; PROTEIN PHOSPHORYLATION; REVIEW; SHIFT WORKER; SUPRACHIASMATIC NUCLEUS; ANIMAL; BRAIN; DIABETES MELLITUS; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; GROWTH, DEVELOPMENT AND AGING; INFLAMMATION; INSULIN RESISTANCE; METABOLISM; OBESITY; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

AGING; ANIMALS; AUTOPHAGY; BRAIN; CALORIC RESTRICTION; CIRCADIAN RHYTHM; DIABETES MELLITUS; ENERGY METABOLISM; EPIGENESIS, GENETIC; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION; HUMANS; INFLAMMATION; INSULIN; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR I; LONGEVITY; MELATONIN; MEMORY; NERVE DEGENERATION; OBESITY; SIGNAL TRANSDUCTION; SIRTUINS;

EID: 84907882606     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150916848     Document Type: Review

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