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Volumn 20, Issue 13, 2010, Pages 1203-1208

AKT and TOR signaling set the pace of the circadian pacemaker

Author keywords

MOLNEURO; SIGNALING

Indexed keywords

CIRCADIAN RHYTHM SIGNALING PROTEIN; DROSOPHILA PROTEIN; PROTEIN KINASE; PROTEIN KINASE B; TARGET OF RAPAMYCIN PROTEIN, DROSOPHILA; TARGET OF RAPAMYCIN KINASE;

EID: 77955420486     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cub.2010.05.027     Document Type: Article
Times cited : (124)

References (39)
  • 1
    • 33845665236 scopus 로고    scopus 로고
    • A sense of time: How molecular clocks organize metabolism
    • A. Kohsaka, and J. Bass A sense of time: How molecular clocks organize metabolism Trends Endocrinol. Metab. 18 2007 4 11
    • (2007) Trends Endocrinol. Metab. , vol.18 , pp. 4-11
    • Kohsaka, A.1    Bass, J.2
  • 2
    • 30044448307 scopus 로고    scopus 로고
    • When the Clock stops ticking, metabolic syndrome explodes
    • B. Staels When the Clock stops ticking, metabolic syndrome explodes Nat. Med. 12 2006 54 55
    • (2006) Nat. Med. , vol.12 , pp. 54-55
    • Staels, B.1
  • 5
    • 0037086001 scopus 로고    scopus 로고
    • Living with lethal PIP3 levels: Viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB
    • H. Stocker, M. Andjelkovic, S. Oldham, M. Laffargue, M.P. Wymann, B.A. Hemmings, and E. Hafen Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB Science 295 2002 2088 2091
    • (2002) Science , vol.295 , pp. 2088-2091
    • Stocker, H.1    Andjelkovic, M.2    Oldham, S.3    Laffargue, M.4    Wymann, M.P.5    Hemmings, B.A.6    Hafen, E.7
  • 6
    • 0033599009 scopus 로고    scopus 로고
    • A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila
    • S.C.P. Renn, J.H. Park, M. Rosbash, J.C. Hall, and P.H. Taghert A pdf neuropeptide gene mutation and ablation of PDF neurons each cause severe abnormalities of behavioral circadian rhythms in Drosophila Cell 99 1999 791 802
    • (1999) Cell , vol.99 , pp. 791-802
    • Renn, S.C.P.1    Park, J.H.2    Rosbash, M.3    Hall, J.C.4    Taghert, P.H.5
  • 7
    • 0036714127 scopus 로고    scopus 로고
    • Akt regulates growth by directly phosphorylating Tsc2
    • C.J. Potter, L.G. Pedraza, and T. Xu Akt regulates growth by directly phosphorylating Tsc2 Nat. Cell Biol. 4 2002 658 665
    • (2002) Nat. Cell Biol. , vol.4 , pp. 658-665
    • Potter, C.J.1    Pedraza, L.G.2    Xu, T.3
  • 8
    • 0033429554 scopus 로고    scopus 로고
    • Mammalian target of rapamycin is a direct target for protein kinase B: Identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation
    • B.T. Navé, D.M. Ouwens, D.J. Withers, D.R. Alessi, and P.R. Shepherd Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation Biochem. J. 344 1999 427 431
    • (1999) Biochem. J. , vol.344 , pp. 427-431
    • Navé, B.T.1    Ouwens, D.M.2    Withers, D.J.3    Alessi, D.R.4    Shepherd, P.R.5
  • 9
    • 5444233787 scopus 로고    scopus 로고
    • Tsc2 is not a critical target of Akt during normal Drosophila development
    • J. Dong, and D. Pan Tsc2 is not a critical target of Akt during normal Drosophila development Genes Dev. 18 2004 2479 2484
    • (2004) Genes Dev. , vol.18 , pp. 2479-2484
    • Dong, J.1    Pan, D.2
  • 10
    • 0036742659 scopus 로고    scopus 로고
    • Inhibition of cellular growth and proliferation by dTOR overexpression in Drosophila
    • K.M. Hennig, and T.P. Neufeld Inhibition of cellular growth and proliferation by dTOR overexpression in Drosophila Genesis 34 2002 107 110
    • (2002) Genesis , vol.34 , pp. 107-110
    • Hennig, K.M.1    Neufeld, T.P.2
  • 12
    • 0038643484 scopus 로고    scopus 로고
    • Rheb promotes cell growth as a component of the insulin/TOR signalling network
    • L.J. Saucedo, X. Gao, D.A. Chiarelli, L. Li, D. Pan, and B.A. Edgar Rheb promotes cell growth as a component of the insulin/TOR signalling network Nat. Cell Biol. 5 2003 566 571
    • (2003) Nat. Cell Biol. , vol.5 , pp. 566-571
    • Saucedo, L.J.1    Gao, X.2    Chiarelli, D.A.3    Li, L.4    Pan, D.5    Edgar, B.A.6
  • 13
    • 33751079895 scopus 로고    scopus 로고
    • Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity
    • Q. Yang, K. Inoki, T. Ikenoue, and K.L. Guan Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity Genes Dev. 20 2006 2820 2832
    • (2006) Genes Dev. , vol.20 , pp. 2820-2832
    • Yang, Q.1    Inoki, K.2    Ikenoue, T.3    Guan, K.L.4
  • 15
    • 33646485688 scopus 로고    scopus 로고
    • TSC1/TSC2 and Rheb have different effects on TORC1 and TORC2 activity
    • Q. Yang, K. Inoki, E. Kim, and K.-L. Guan TSC1/TSC2 and Rheb have different effects on TORC1 and TORC2 activity Proc. Natl. Acad. Sci. USA 103 2006 6811 6816
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 6811-6816
    • Yang, Q.1    Inoki, K.2    Kim, E.3    Guan, K.-L.4
  • 16
    • 0036741749 scopus 로고    scopus 로고
    • Altering Drosophila S6 kinase activity is consistent with a role for S6 kinase in growth
    • H. Barcelo, and M.J. Stewart Altering Drosophila S6 kinase activity is consistent with a role for S6 kinase in growth Genesis 34 2002 83 85
    • (2002) Genesis , vol.34 , pp. 83-85
    • Barcelo, H.1    Stewart, M.J.2
  • 17
    • 27744588780 scopus 로고    scopus 로고
    • Tuberous sclerosis: A GAP at the crossroads of multiple signaling pathways
    • D.J. Kwiatkowski, and B.D. Manning Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways Hum. Mol. Genet. 14 2005 R251 R258
    • (2005) Hum. Mol. Genet. , vol.14
    • Kwiatkowski, D.J.1    Manning, B.D.2
  • 18
    • 33750040886 scopus 로고    scopus 로고
    • S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt
    • H.H. Zhang, A.I. Lipovsky, C.C. Dibble, M. Sahin, and B.D. Manning S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt Mol. Cell 24 2006 185 197
    • (2006) Mol. Cell , vol.24 , pp. 185-197
    • Zhang, H.H.1    Lipovsky, A.I.2    Dibble, C.C.3    Sahin, M.4    Manning, B.D.5
  • 19
    • 2442676633 scopus 로고    scopus 로고
    • Functional studies of shaggy/glycogen synthase kinase 3 phosphorylation sites in Drosophila melanogaster
    • D. Papadopoulou, M.W. Bianchi, and M. Bourouis Functional studies of shaggy/glycogen synthase kinase 3 phosphorylation sites in Drosophila melanogaster Mol. Cell. Biol. 24 2004 4909 4919
    • (2004) Mol. Cell. Biol. , vol.24 , pp. 4909-4919
    • Papadopoulou, D.1    Bianchi, M.W.2    Bourouis, M.3
  • 20
    • 33144465537 scopus 로고    scopus 로고
    • Nuclear receptor Rev-erb{alpha} is a critical lithium-sensitive component of the circadian clock
    • L. Yin, J. Wang, P.S. Klein, and M.A. Lazar Nuclear receptor Rev-erb{alpha} is a critical lithium-sensitive component of the circadian clock Science 311 2006 1002 1005
    • (2006) Science , vol.311 , pp. 1002-1005
    • Yin, L.1    Wang, J.2    Klein, P.S.3    Lazar, M.A.4
  • 21
    • 23844460834 scopus 로고    scopus 로고
    • A role for glycogen synthase kinase-3β in the mammalian circadian clock
    • C. Iitaka, K. Miyazaki, T. Akaike, and N. Ishida A role for glycogen synthase kinase-3β in the mammalian circadian clock J. Biol. Chem. 280 2005 29397 29402
    • (2005) J. Biol. Chem. , vol.280 , pp. 29397-29402
    • Iitaka, C.1    Miyazaki, K.2    Akaike, T.3    Ishida, N.4
  • 22
    • 0035875069 scopus 로고    scopus 로고
    • A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock
    • S. Martinek, S. Inonog, A.S. Manoukian, and M.W. Young A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clock Cell 105 2001 769 779
    • (2001) Cell , vol.105 , pp. 769-779
    • Martinek, S.1    Inonog, S.2    Manoukian, A.S.3    Young, M.W.4
  • 23
    • 27744493091 scopus 로고    scopus 로고
    • A resetting signal between Drosophila pacemakers synchronizes morning and evening activity
    • D. Stoleru, Y. Peng, P. Nawathean, and M. Rosbash A resetting signal between Drosophila pacemakers synchronizes morning and evening activity Nature 438 2005 238 242
    • (2005) Nature , vol.438 , pp. 238-242
    • Stoleru, D.1    Peng, Y.2    Nawathean, P.3    Rosbash, M.4
  • 24
    • 0033637383 scopus 로고    scopus 로고
    • Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus
    • F. Damiola, N. Le Minh, N. Preitner, B. Kornmann, F. Fleury-Olela, and U. Schibler Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus Genes Dev. 14 2000 2950 2961
    • (2000) Genes Dev. , vol.14 , pp. 2950-2961
    • Damiola, F.1    Le Minh, N.2    Preitner, N.3    Kornmann, B.4    Fleury-Olela, F.5    Schibler, U.6
  • 25
    • 0035059442 scopus 로고    scopus 로고
    • Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleus
    • R. Hara, K. Wan, H. Wakamatsu, R. Aida, T. Moriya, M. Akiyama, and S. Shibata Restricted feeding entrains liver clock without participation of the suprachiasmatic nucleus Genes Cells 6 2001 269 278
    • (2001) Genes Cells , vol.6 , pp. 269-278
    • Hara, R.1    Wan, K.2    Wakamatsu, H.3    Aida, R.4    Moriya, T.5    Akiyama, M.6    Shibata, S.7
  • 26
    • 0034708544 scopus 로고    scopus 로고
    • Nonphotic phase-shifting in Clock mutant mice
    • E. Challet, J.S. Takahashi, and F.W. Turek Nonphotic phase-shifting in Clock mutant mice Brain Res. 859 2000 398 403
    • (2000) Brain Res. , vol.859 , pp. 398-403
    • Challet, E.1    Takahashi, J.S.2    Turek, F.W.3
  • 28
    • 58149464684 scopus 로고    scopus 로고
    • High-fat diet delays and fasting advances the circadian expression of adiponectin signaling components in mouse liver
    • M. Barnea, Z. Madar, and O. Froy High-fat diet delays and fasting advances the circadian expression of adiponectin signaling components in mouse liver Endocrinology 150 2009 161 168
    • (2009) Endocrinology , vol.150 , pp. 161-168
    • Barnea, M.1    Madar, Z.2    Froy, O.3
  • 29
    • 0035919479 scopus 로고    scopus 로고
    • Regulation of Clock and NPAS2 DNA binding by the redox state of NAD cofactors
    • J. Rutter, M. Reick, L.C. Wu, and S.L. McKnight Regulation of Clock and NPAS2 DNA binding by the redox state of NAD cofactors Science 293 2001 510 514
    • (2001) Science , vol.293 , pp. 510-514
    • Rutter, J.1    Reick, M.2    Wu, L.C.3    McKnight, S.L.4
  • 36
    • 58849156810 scopus 로고    scopus 로고
    • Ribosomal S6 kinase cooperates with casein kinase 2 to modulate the Drosophila circadian molecular oscillator
    • B. Akten, M.M. Tangredi, E. Jauch, M.A. Roberts, F. Ng, T. Raabe, and F.R. Jackson Ribosomal S6 kinase cooperates with casein kinase 2 to modulate the Drosophila circadian molecular oscillator J. Neurosci. 29 2009 466 475
    • (2009) J. Neurosci. , vol.29 , pp. 466-475
    • Akten, B.1    Tangredi, M.M.2    Jauch, E.3    Roberts, M.A.4    Ng, F.5    Raabe, T.6    Jackson, F.R.7
  • 38
    • 54449085416 scopus 로고    scopus 로고
    • Physiological significance of a peripheral tissue circadian clock
    • K.A. Lamia, K.-F. Storch, and C.J. Weitz Physiological significance of a peripheral tissue circadian clock Proc. Natl. Acad. Sci. USA 105 2008 15172 15177
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 15172-15177
    • Lamia, K.A.1    Storch, K.-F.2    Weitz, C.J.3
  • 39
    • 0034982971 scopus 로고    scopus 로고
    • TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth
    • X. Gao, and D. Pan TSC1 and TSC2 tumor suppressors antagonize insulin signaling in cell growth Genes Dev. 15 2001 1383 1392
    • (2001) Genes Dev. , vol.15 , pp. 1383-1392
    • Gao, X.1    Pan, D.2


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