SIRT1 inhibition by melatonin exerts antitumor activity in human osteosarcoma cells

European Journal of Pharmacology

Volumn 715, Issue 1-3, 2013, Pages 219-229

  Cheng, Yedong ^a   Cai, Liping ^a   Jiang, Peng ^a,b   Wang, Jiabo ^a   Gao, Chao ^a   Feng, Haibo ^a   Wang, Changchao ^a   Pan, Haiyuan ^a   Yang, Yang ^a,c  

^a The 82th Hospital of PLA   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Antitumor; Melatonin; Osteosarcoma; P53; SIRT1

Indexed keywords

CYTOCHROME C; GLUTATHIONE; MELATONIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SIRTINOL; SIRTUIN 1; SMALL INTERFERING RNA;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL ADHESION; CELL MIGRATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG POTENTIATION; HUMAN; HUMAN CELL; OSTEOSARCOMA CELL; PRIORITY JOURNAL; UPREGULATION;

ANTITUMOR; MELATONIN; OSTEOSARCOMA; P53; SIRT1;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; GLUTATHIONE; HISTONE DEACETYLASE INHIBITORS; HUMANS; MELATONIN; MITOCHONDRIA; OSTEOSARCOMA; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; SIRTUIN 1;

EID: 84885485876     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.05.017     Document Type: Article

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