Genome-wide profiling in melatonin-exposed human breast cancer cell lines identifies differentially methylated genes involved in the anticancer effect of melatonin

Journal of Pineal Research

Volumn 54, Issue 1, 2013, Pages 80-88

  Lee, Seung Eun ^a   Kim, Seung Jun ^b   Yoon, Hyo Jeong ^b,c   Yu, So Yeon ^b,d   Yang, Hana ^a   Jeong, Seong Il ^a   Hwang, Seung Yong ^b,d   Park, Cheung Seog ^a   Park, Yong Seek ^a  

^a Kyung Hee University Hospital   (South Korea)

^b GenoCheck Co Ltd   (South Korea)

^c Hankyong National University   (South Korea)

^d Hanyang University   (South Korea)

Author keywords

Anticancer effect; Breast cancer; Gene expression; Melatonin; Methylation profiling

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 3; MELATONIN; MESSENGER RNA; TRANSCRIPTION FACTOR POU4F2;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER CELL; CELL STRAIN MCF 7; CONTROLLED STUDY; CPG ISLAND; DNA DETERMINATION; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; FEMALE; GENE EXPRESSION; GENE LOCATION; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; MOLECULAR MECHANICS; ONCOGENE; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION;

ANTICANCER EFFECT; BREAST CANCER; GENE EXPRESSION; MELATONIN; METHYLATION PROFILING;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA METHYLATION; DOWN-REGULATION; EARLY GROWTH RESPONSE PROTEIN 3; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE ONTOLOGY; GENES, TUMOR SUPPRESSOR; GLYPICANS; HUMANS; MELATONIN; ONCOGENES; TRANSCRIPTION FACTOR BRN-3B; UP-REGULATION;

EID: 84872682556     PISSN: 07423098     EISSN: 1600079X     Source Type: Journal    
DOI: 10.1111/j.1600-079X.2012.01027.x     Document Type: Article

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