Post-transcriptional regulation of IGF1R by key microRNAs in long-lived mutant mice

Aging Cell

Volumn 10, Issue 6, 2011, Pages 1080-1088

  Liang, Ruqiang ^a   Khanna, Amit ^a   Muthusamy, Senthilkumar ^a   Li, Na ^a   Sarojini, Harshini ^a   Kopchick, John J ^b   Masternak, Michal M ^c,d,e   Bartke, Andrzej ^c   Wang, Eugenia ^a  

^a University of Louisville School of Medicine   (United States)

^b OHIO UNIVERSITY   (United States)

^c SOUTHERN ILLINOIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE   (United States)

^e INSTITUTE OF HUMAN GENETICS   (Poland)

Author keywords

Aging; Ames dwarf mice and GHRKO mice; Cognitive robustness and longevity; Growth hormone; IGF1; IGF1R; MicroRNA; MiR 470; MiR 669b; MiR 681

Indexed keywords

GROWTH HORMONE; MICRORNA; MICRORNA 470; MICRORNA 669B; MICRORNA 681; PROTEIN KINASE B; SOMATOMEDIN C; TRANSCRIPTION FACTOR FKHRL1; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BRAIN; CELL CULTURE; GENE CONTROL; GENE EXPRESSION; GENETIC REGULATION; GENETIC TRANSCRIPTION; IMMUNOBLOTTING; MOUSE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; UPREGULATION;

ANIMALS; CELL PROLIFERATION; FORKHEAD TRANSCRIPTION FACTORS; GENE DELETION; GENE EXPRESSION REGULATION; GROWTH HORMONE; HIPPOCAMPUS; INSULIN-LIKE GROWTH FACTOR I; LONGEVITY; MICE; MICE, TRANSGENIC; MICRORNAS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, IGF TYPE 1; SIGNAL TRANSDUCTION; TRANSFECTION;

MUS;

EID: 81155124412     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2011.00751.x     Document Type: Article

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