-
1
-
-
84894297176
-
Running-induced epigenetic and gene expression changes in the adolescent brain
-
doi: 10.1016/j.ijdevneu.2012.11.002
-
Abel, J. L., and Rissman, E. F. (2013). Running-induced epigenetic and gene expression changes in the adolescent brain. Int. J. Dev. Neurosci. 31, 382-390. doi: 10.1016/j.ijdevneu.2012.11.002
-
(2013)
Int. J. Dev. Neurosci.
, vol.31
, pp. 382-390
-
-
Abel, J.L.1
Rissman, E.F.2
-
2
-
-
84878798054
-
Epigenetic determinants of healthy and diseased brain aging and cognition
-
doi: 10.1001/jamaneurol.2013.1459
-
Akbarian, S., Beeri, M. S., and Haroutunian, V. (2013). Epigenetic determinants of healthy and diseased brain aging and cognition. JAMA Neurol. 70, 711-718. doi: 10.1001/jamaneurol.2013.1459
-
(2013)
JAMA Neurol
, vol.70
, pp. 711-718
-
-
Akbarian, S.1
Beeri, M.S.2
Haroutunian, V.3
-
3
-
-
84873651180
-
Long-term exercise modulates hippocampal gene expression in senescent female mice
-
doi: 10.3233/JAD-121264
-
Alvarez-Lopez, M. J., Castro-Freire, M., Cosin-Tomas, M., Sanchez-Roige, S., Lalanza, J. F., Del Valle, J., et al. (2013). Long-term exercise modulates hippocampal gene expression in senescent female mice. J. Alzheimers Dis. 33, 1177-1190. doi: 10.3233/JAD-121264
-
(2013)
J. Alzheimers Dis.
, vol.33
, pp. 1177-1190
-
-
Alvarez-Lopez, M.J.1
Castro-Freire, M.2
Cosin-Tomas, M.3
Sanchez-Roige, S.4
Lalanza, J.F.5
Del Valle, J.6
-
4
-
-
67349213205
-
Synaptic degeneration in Alzheimer's disease
-
doi: 10.1007/s00401-009-0536-x
-
Arendt, T. (2009). Synaptic degeneration in Alzheimer's disease. Acta Neuropathol. 118, 167-179. doi: 10.1007/s00401-009-0536-x
-
(2009)
Acta Neuropathol
, vol.118
, pp. 167-179
-
-
Arendt, T.1
-
6
-
-
22844440427
-
Identification of hundreds of conserved and nonconserved human microRNAs
-
doi: 10.1038/ng1590
-
Bentwich, I., Avniel, A., Karov, Y., Aharonov, R., Gilad, S., Barad, O., et al. (2005). Identification of hundreds of conserved and nonconserved human microRNAs. Nat. Genet. 37, 766-770. doi: 10.1038/ng1590
-
(2005)
Nat. Genet.
, vol.37
, pp. 766-770
-
-
Bentwich, I.1
Avniel, A.2
Karov, Y.3
Aharonov, R.4
Gilad, S.5
Barad, O.6
-
7
-
-
70949107340
-
-
doi: 10.1371/journal.pone.0007901
-
Bruel-Jungerman, E., Veyrac, A., Dufour, F., Horwood, J., Laroche, S., and Davis, S. (2009). Inhibition of PI3K-Akt signaling blocks exercise-mediated enhancement of adult neurogenesis and synaptic plasticity in the dentate gyrus. PLoS ONE 4:e7901. doi: 10.1371/journal.pone.0007901
-
(2009)
Inhibition of PI3K-Akt signaling blocks exercise-mediated enhancement of adult neurogenesis and synaptic plasticity in the dentate gyrus. PLoS ONE
, vol.4
-
-
Bruel-Jungerman, E.1
Veyrac, A.2
Dufour, F.3
Horwood, J.4
Laroche, S.5
Davis, S.6
-
8
-
-
44649188552
-
-
doi: 10.1111/j.1460-9568.2008.06230.x
-
Chandramohan, Y., Droste, S. K., Arthur, J. S., and Reul, J. M. (2008). The forced swimming-induced behavioural immobility response involves histone H3 phospho-acetylation and c-Fos induction in dentate gyrus granule neurons via activation of the N-methyl-D-aspartate/extracellular signal-regulated kinase/mitogen- and stress-activated kinase signalling pathway. Eur. J. Neurosci. 27, 2701-2713. doi: 10.1111/j.1460-9568.2008.06230.x
-
(2008)
, vol.27
, pp. 2701-2713
-
-
Chandramohan, Y.1
Droste, S.K.2
Arthur, J.S.3
Reul, J.M.4
-
9
-
-
81355138837
-
Insulin-like growth factor I signaling for brain recovery and exercise ability in brain ischemic rats
-
doi: 10.1249/MSS.0b013e318223b5d9
-
Chang, H. C., Yang, Y. R., Wang, P. S., Kuo, C. H., and Wang, R. Y. (2011). Insulin-like growth factor I signaling for brain recovery and exercise ability in brain ischemic rats. Med. Sci. Sports Exerc. 43, 2274-2280. doi: 10.1249/MSS.0b013e318223b5d9
-
(2011)
Med. Sci. Sports Exerc.
, vol.43
, pp. 2274-2280
-
-
Chang, H.C.1
Yang, Y.R.2
Wang, P.S.3
Kuo, C.H.4
Wang, R.Y.5
-
10
-
-
84895831104
-
Nodes and biological processes identified on the basis of network analysis in the brain of the senescence accelerated mice as an Alzheimer's disease animal model
-
doi: 10.3389/fnagi.2013.00065
-
Cheng, X. R., Cui, X. L., Zheng, Y., Zhang, G. R., Li, P., Huang, H., et al. (2013a). Nodes and biological processes identified on the basis of network analysis in the brain of the senescence accelerated mice as an Alzheimer's disease animal model. Front. Aging Neurosci. 5:65. doi: 10.3389/fnagi.2013.00065
-
(2013)
Front. Aging Neurosci.
, vol.5
-
-
Cheng, X.R.1
Cui, X.L.2
Zheng, Y.3
Zhang, G.R.4
Li, P.5
Huang, H.6
-
11
-
-
84890189246
-
-
doi: 10.1016/j.arr.2013.10.002
-
Cheng, X. R., Zhou, W. X., and Zhang, Y. X. (2013b). The behavioral, pathological and therapeutic features of the senescence-accelerated mouse prone 8 strain as an Alzheimer's disease animal model. Ageing Res. Rev. 13C, 13-37. doi: 10.1016/j.arr.2013.10.002
-
(2013)
-
-
Cheng, X.R.1
Zhou, W.X.2
Zhang, Y.X.3
-
12
-
-
47849124269
-
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways
-
Cogswell, J. P., Ward, J., Taylor, I. A., Waters, M., Shi, Y., Cannon, B., et al. (2008). Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways. J. Alzheimers Dis. 14, 27-41.
-
(2008)
J. Alzheimers Dis.
, vol.14
, pp. 27-41
-
-
Cogswell, J.P.1
Ward, J.2
Taylor, I.A.3
Waters, M.4
Shi, Y.5
Cannon, B.6
-
13
-
-
63049117086
-
-
doi: 10.1371/journal.pone.0004330
-
Collins, A., Hill, L. E., Chandramohan, Y., Whitcomb, D., Droste, S. K., and Reul, J. M. (2009). Exercise improves cognitive responses to psychological stress through enhancement of epigenetic mechanisms and gene expression in the dentate gyrus. PLoS ONE 4:e4330. doi: 10.1371/journal.pone.0004330
-
(2009)
Exercise improves cognitive responses to psychological stress through enhancement of epigenetic mechanisms and gene expression in the dentate gyrus. PLoS ONE
, vol.4
-
-
Collins, A.1
Hill, L.E.2
Chandramohan, Y.3
Whitcomb, D.4
Droste, S.K.5
Reul, J.M.6
-
14
-
-
66349120438
-
-
doi: 10.4161/epi.4.1.7604
-
Crepaldi, L., and Riccio, A. (2009). Chromatin learns to behave. Epigenetics 4, 23-26. doi: 10.4161/epi.4.1.7604
-
(2009)
, vol.4
, pp. 23-26
-
-
Crepaldi, L.1
Riccio, A.2
-
15
-
-
67149099680
-
-
doi: 10.1038/nature08085
-
Dang, W., Steffen, K. K., Perry, R., Dorsey, J. A., Johnson, F. B., Shilatifard, A., et al. (2009). Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature 459, 802-807. doi: 10.1038/nature08085
-
(2009)
Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature
, vol.459
, pp. 802-807
-
-
Dang, W.1
Steffen, K.K.2
Perry, R.3
Dorsey, J.A.4
Johnson, F.B.5
Shilatifard, A.6
-
16
-
-
79960557983
-
Cerebral amyloid angiopathy, blood-brain barrier disruption and amyloid accumulation in SAMP8 mice
-
doi: 10.1159/000324757
-
Del Valle, J., Duran-Vilaregut, J., Manich, G., Pallas, M., Camins, A., Vilaplana, J., et al. (2011). Cerebral amyloid angiopathy, blood-brain barrier disruption and amyloid accumulation in SAMP8 mice. Neurodegener. Dis. 8, 421-429. doi: 10.1159/000324757
-
(2011)
Neurodegener. Dis.
, vol.8
, pp. 421-429
-
-
Del Valle, J.1
Duran-Vilaregut, J.2
Manich, G.3
Pallas, M.4
Camins, A.5
Vilaplana, J.6
-
17
-
-
84860153750
-
Chromatin modification and senescence
-
doi: 10.2174/138161212799859693
-
Di Bernardo, G., Cipollaro, M., and Galderisi, U. (2012). Chromatin modification and senescence. Curr. Pharm. Des. 18, 1686-1693. doi: 10.2174/138161212799859693
-
(2012)
Curr. Pharm. Des.
, vol.18
, pp. 1686-1693
-
-
Di Bernardo, G.1
Cipollaro, M.2
Galderisi, U.3
-
18
-
-
33749167093
-
-
doi: 10.1038/oby.2006.46
-
Dishman, R. K., Berthoud, H. R., Booth, F. W., Cotman, C. W., Edgerton, V. R., Fleshner, M. R., et al. (2006). Neurobiology of exercise. Obesity (Silver Spring) 14, 345-356. doi: 10.1038/oby.2006.46
-
(2006)
Neurobiology of exercise. Obesity (Silver Spring)
, vol.14
, pp. 345-356
-
-
Dishman, R.K.1
Berthoud, H.R.2
Booth, F.W.3
Cotman, C.W.4
Edgerton, V.R.5
Fleshner, M.R.6
-
19
-
-
84883524497
-
Sirtuins: from metabolic regulation to brain aging
-
doi: 10.3389/fnagi.2013.00036
-
Duan, W. (2013). Sirtuins: from metabolic regulation to brain aging. Front. Aging Neurosci. 5:36. doi: 10.3389/fnagi.2013.00036
-
(2013)
Front. Aging Neurosci.
, vol.5
-
-
Duan, W.1
-
20
-
-
70350257622
-
-
doi: 10.1007/s00421-009-1143-1
-
Dumke, C. L., Mark Davis, J., Angela Murphy, E., Nieman, D. C., Carmichael, M. D., Quindry, J. C., et al. (2009). Successive bouts of cycling stimulates genes associated with mitochondrial biogenesis. Eur. J. Appl. Physiol. 107, 419-427. doi: 10.1007/s00421-009-1143-1
-
(2009)
, vol.107
, pp. 419-427
-
-
Dumke, C.L.1
Mark Davis, J.2
Angela Murphy, E.3
Nieman, D.C.4
Carmichael, M.D.5
Quindry, J.C.6
-
21
-
-
84880592726
-
-
doi: 10.1002/syn.21668
-
Elfving, B., Christensen, T., Ratner, C., Wienecke, J., and Klein, A. B. (2013). Transient activation of mTOR following forced treadmill exercise in rats. Synapse 67, 620-625. doi: 10.1002/syn.21668
-
(2013)
Transient activation of mTOR following forced treadmill exercise in rats. Synapse
, vol.67
, pp. 620-625
-
-
Elfving, B.1
Christensen, T.2
Ratner, C.3
Wienecke, J.4
Klein, A.B.5
-
22
-
-
39449118273
-
Exercise training promotes SIRT1 activity in aged rats
-
doi: 10.1089/rej.2007.0576
-
Ferrara, N., Rinaldi, B., Corbi, G., Conti, V., Stiuso, P., Boccuti, S., et al. (2008). Exercise training promotes SIRT1 activity in aged rats. Rejuvenation Res. 11, 139-150. doi: 10.1089/rej.2007.0576
-
(2008)
Rejuvenation Res
, vol.11
, pp. 139-150
-
-
Ferrara, N.1
Rinaldi, B.2
Corbi, G.3
Conti, V.4
Stiuso, P.5
Boccuti, S.6
-
23
-
-
34248523169
-
-
doi: 10.1038/nature05772
-
Fischer, A., Sananbenesi, F., Wang, X., Dobbin, M., and Tsai, L. H. (2007). Recovery of learning and memory is associated with chromatin remodelling. Nature 447, 178-182. doi: 10.1038/nature05772
-
(2007)
Recovery of learning and memory is associated with chromatin remodelling. Nature
, vol.447
, pp. 178-182
-
-
Fischer, A.1
Sananbenesi, F.2
Wang, X.3
Dobbin, M.4
Tsai, L.H.5
-
24
-
-
84856738488
-
Post-transcriptional trafficking and regulation of neuronal gene expression
-
doi: 10.1007/s12035-011-8222-0
-
Goldie, B. J., and Cairns, M. J. (2012). Post-transcriptional trafficking and regulation of neuronal gene expression. Mol. Neurobiol. 45, 99-108. doi: 10.1007/s12035-011-8222-0
-
(2012)
Mol. Neurobiol.
, vol.45
, pp. 99-108
-
-
Goldie, B.J.1
Cairns, M.J.2
-
25
-
-
56749180855
-
Brain-derived neurotrophic factor functions as a metabotrophin to mediate the effects of exercise on cognition
-
doi: 10.1111/j.1460-9568.2008.06524.x
-
Gomez-Pinilla, F., Vaynman, S., and Ying, Z. (2008). Brain-derived neurotrophic factor functions as a metabotrophin to mediate the effects of exercise on cognition. Eur. J. Neurosci. 28, 2278-2287. doi: 10.1111/j.1460-9568.2008.06524.x
-
(2008)
Eur. J. Neurosci.
, vol.28
, pp. 2278-2287
-
-
Gomez-Pinilla, F.1
Vaynman, S.2
Ying, Z.3
-
26
-
-
79251578642
-
Exercise impacts brain-derived neurotrophic factor plasticity by engaging mechanisms of epigenetic regulation
-
doi: 10.1111/j.1460-9568.2010.07508.x
-
Gomez-Pinilla, F., Zhuang, Y., Feng, J., Ying, Z., and Fan, G. (2011). Exercise impacts brain-derived neurotrophic factor plasticity by engaging mechanisms of epigenetic regulation. Eur. J. Neurosci. 33, 383-390. doi: 10.1111/j.1460-9568.2010.07508.x
-
(2011)
Eur. J. Neurosci.
, vol.33
, pp. 383-390
-
-
Gomez-Pinilla, F.1
Zhuang, Y.2
Feng, J.3
Ying, Z.4
Fan, G.5
-
27
-
-
77954660029
-
Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans
-
doi: 10.1038/nature09195
-
Greer, E. L., Maures, T. J., Hauswirth, A. G., Green, E. M., Leeman, D. S., Maro, G. S., et al. (2010). Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans. Nature 466, 383-387. doi: 10.1038/nature09195
-
(2010)
Nature
, vol.466
, pp. 383-387
-
-
Greer, E.L.1
Maures, T.J.2
Hauswirth, A.G.3
Green, E.M.4
Leeman, D.S.5
Maro, G.S.6
-
28
-
-
44049108170
-
Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression
-
doi: 10.1073/pnas.0710263105
-
Hebert, S. S., Horre, K., Nicolai, L., Papadopoulou, A. S., Mandemakers, W., Silahtaroglu, A. N., et al. (2008). Loss of microRNA cluster miR-29a/b-1 in sporadic Alzheimer's disease correlates with increased BACE1/beta-secretase expression. Proc. Natl. Acad. Sci. U.S.A. 105, 6415-6420. doi: 10.1073/pnas.0710263105
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 6415-6420
-
-
Hebert, S.S.1
Horre, K.2
Nicolai, L.3
Papadopoulou, A.S.4
Mandemakers, W.5
Silahtaroglu, A.N.6
-
29
-
-
84861039037
-
Aging, atherosclerosis, and IGF-1
-
doi: 10.1093/gerona/gls102
-
Higashi, Y., Sukhanov, S., Anwar, A., Shai, S. Y., and Delafontaine, P. (2012). Aging, atherosclerosis, and IGF-1. J. Gerontol. A Biol. Sci. Med. Sci. 67, 626-639. doi: 10.1093/gerona/gls102
-
(2012)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.67
, pp. 626-639
-
-
Higashi, Y.1
Sukhanov, S.2
Anwar, A.3
Shai, S.Y.4
Delafontaine, P.5
-
30
-
-
84878115461
-
Aging epigenetics: causes and consequences
-
doi: 10.1016/j.mam.2012.06.006
-
Huidobro, C., Fernandez, A. F., and Fraga, M. F. (2013). Aging epigenetics: causes and consequences. Mol. Aspects Med. 34, 765-781. doi: 10.1016/j.mam.2012.06.006
-
(2013)
Mol. Aspects Med.
, vol.34
, pp. 765-781
-
-
Huidobro, C.1
Fernandez, A.F.2
Fraga, M.F.3
-
31
-
-
0037372003
-
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
-
doi: 10.1038/ng1089
-
Jaenisch, R., and Bird, A. (2003). Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet. 33(Suppl.), 245-254. doi: 10.1038/ng1089
-
(2003)
Nat. Genet.
, vol.33
, Issue.SUPPL.
-
-
Jaenisch, R.1
Bird, A.2
-
32
-
-
84864700183
-
-
doi: 10.1038/nm.2828
-
Jakovcevski, M., and Akbarian, S. (2012). Epigenetic mechanisms in neurological disease. Nat. Med. 18, 1194-1204. doi: 10.1038/nm.2828
-
(2012)
, vol.18
, pp. 1194-1204
-
-
Jakovcevski, M.1
Akbarian, S.2
-
33
-
-
84867810635
-
microRNA in aging: from discovery to biology
-
doi: 10.2174/138920212803251436
-
Jung, H. J., and Suh, Y. (2012). microRNA in aging: from discovery to biology. Curr. Genomics 13, 548-557. doi: 10.2174/138920212803251436
-
(2012)
Curr. Genomics
, vol.13
, pp. 548-557
-
-
Jung, H.J.1
Suh, Y.2
-
34
-
-
80052326256
-
Neurophysiological and epigenetic effects of physical exercise on the aging process
-
doi: 10.1016/j.arr.2011.05.002
-
Kaliman, P., Parrizas, M., Lalanza, J. F., Camins, A., Escorihuela, R. M., and Pallas, M. (2011). Neurophysiological and epigenetic effects of physical exercise on the aging process. Ageing Res. Rev. 10, 475-486. doi: 10.1016/j.arr.2011.05.002
-
(2011)
Ageing Res. Rev.
, vol.10
, pp. 475-486
-
-
Kaliman, P.1
Parrizas, M.2
Lalanza, J.F.3
Camins, A.4
Escorihuela, R.M.5
Pallas, M.6
-
35
-
-
76749091005
-
-
doi: 10.1038/npp.2009.197
-
Kilgore, M., Miller, C. A., Fass, D. M., Hennig, K. M., Haggarty, S. J., Sweatt, J. D., et al. (2010). Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease. Neuropsychopharmacology 35, 870-880. doi: 10.1038/npp.2009.197
-
(2010)
Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease. Neuropsychopharmacology
, vol.35
, pp. 870-880
-
-
Kilgore, M.1
Miller, C.A.2
Fass, D.M.3
Hennig, K.M.4
Haggarty, S.J.5
Sweatt, J.D.6
-
36
-
-
74149085437
-
Exercise alters SIRT1, SIRT6
-
doi: 10.1016/j.mad.2009.11.002
-
Koltai, E., Szabo, Z., Atalay, M., Boldogh, I., Naito, H., Goto, S., et al. (2010). Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats. Mech. Ageing Dev. 131, 21-28. doi: 10.1016/j.mad.2009.11.002
-
(2010)
NAD and NAMPT levels in skeletal muscle of aged rats. Mech. Ageing Dev.
, vol.131
, pp. 21-28
-
-
Koltai, E.1
Szabo, Z.2
Atalay, M.3
Boldogh, I.4
Naito, H.5
Goto, S.6
-
37
-
-
84884959481
-
Alteration of the microRNA network during the progression of Alzheimer's disease
-
doi: 10.1002/emmm.201201974
-
Lau, P., Bossers, K., Janky, R., Salta, E., Frigerio, C. S., Barbash, S., et al. (2013). Alteration of the microRNA network during the progression of Alzheimer's disease. EMBO Mol. Med. 5, 1613-1634. doi: 10.1002/emmm.201201974
-
(2013)
EMBO Mol. Med.
, vol.5
, pp. 1613-1634
-
-
Lau, P.1
Bossers, K.2
Janky, R.3
Salta, E.4
Frigerio, C.S.5
Barbash, S.6
-
38
-
-
0242439348
-
Regulating histone acetyltransferases and deacetylases
-
doi: 10.1038/sj.embor.embor941
-
Legube, G., and Trouche, D. (2003). Regulating histone acetyltransferases and deacetylases. EMBO Rep. 4, 944-947. doi: 10.1038/sj.embor.embor941
-
(2003)
EMBO Rep
, vol.4
, pp. 944-947
-
-
Legube, G.1
Trouche, D.2
-
39
-
-
68649100731
-
Epigenetic control of microRNA expression and aging
-
doi: 10.2174/138920209788185225
-
Liang, R., Bates, D. J., and Wang, E. (2009). Epigenetic control of microRNA expression and aging. Curr. Genomics 10, 184-193. doi: 10.2174/138920209788185225
-
(2009)
Curr. Genomics
, vol.10
, pp. 184-193
-
-
Liang, R.1
Bates, D.J.2
Wang, E.3
-
40
-
-
78650171237
-
Effects of voluntary physical exercise on adult hippocampal neurogenesis and behavior of Ts65Dn mice, a model of Down syndrome
-
doi: 10.1016/j.neuroscience.2010.09.043
-
Llorens-Martin, M. V., Rueda, N., Tejeda, G. S., Florez, J., Trejo, J. L., and Martinez-Cue, C. (2010). Effects of voluntary physical exercise on adult hippocampal neurogenesis and behavior of Ts65Dn mice, a model of Down syndrome. Neuroscience 171, 1228-1240. doi: 10.1016/j.neuroscience.2010.09.043
-
(2010)
Neuroscience
, vol.171
, pp. 1228-1240
-
-
Llorens-Martin, M.V.1
Rueda, N.2
Tejeda, G.S.3
Florez, J.4
Trejo, J.L.5
Martinez-Cue, C.6
-
41
-
-
84878864199
-
-
doi: 10.1016/j.cell.2013.05.039
-
Lopez-Otin, C., Blasco, M. A., Partridge, L., Serrano, M., and Kroemer, G. (2013). The hallmarks of aging. Cell 153, 1194-1217. doi: 10.1016/j.cell.2013.05.039
-
(2013)
The hallmarks of aging. Cell
, vol.153
, pp. 1194-1217
-
-
Lopez-Otin, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
42
-
-
84873701571
-
Treadmill exercise induces age-related changes in aversive memory, neuroinflammatory and epigenetic processes in the rat hippocampus
-
doi: 10.1016/j.nlm.2013.01.007
-
Lovatel, G. A., Elsner, V. R., Bertoldi, K., Vanzella, C., Moyses Fdos, S., Vizuete, A., et al. (2013). Treadmill exercise induces age-related changes in aversive memory, neuroinflammatory and epigenetic processes in the rat hippocampus. Neurobiol. Learn. Mem. 101, 94-102. doi: 10.1016/j.nlm.2013.01.007
-
(2013)
Neurobiol. Learn. Mem.
, vol.101
, pp. 94-102
-
-
Lovatel, G.A.1
Elsner, V.R.2
Bertoldi, K.3
Vanzella, C.4
Moyses Fdos, S.5
Vizuete, A.6
-
43
-
-
33847203593
-
Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus
-
doi: 10.1097/WNR.0b013e3280148e8b
-
Lukiw, W. J. (2007). Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus. Neuroreport 18, 297-300. doi: 10.1097/WNR.0b013e3280148e8b
-
(2007)
Neuroreport
, vol.18
, pp. 297-300
-
-
Lukiw, W.J.1
-
44
-
-
68649092030
-
microRNA: implications for Alzheimer disease and other human CNS disorders
-
doi: 10.2174/138920209788185252
-
Maes, O. C., Chertkow, H. M., Wang, E., and Schipper, H. M. (2009). microRNA: implications for Alzheimer disease and other human CNS disorders. Curr. Genomics 10, 154-168. doi: 10.2174/138920209788185252
-
(2009)
Curr. Genomics
, vol.10
, pp. 154-168
-
-
Maes, O.C.1
Chertkow, H.M.2
Wang, E.3
Schipper, H.M.4
-
45
-
-
79958769568
-
Epigenetic mechanisms in Alzheimer's disease
-
doi: 10.1016/j.neurobiolaging.2010.08.017
-
Mastroeni, D., Grover, A., Delvaux, E., Whiteside, C., Coleman, P. D., and Rogers, J. (2011). Epigenetic mechanisms in Alzheimer's disease. Neurobiol. Aging 32, 1161-1180. doi: 10.1016/j.neurobiolaging.2010.08.017
-
(2011)
Neurobiol. Aging
, vol.32
, pp. 1161-1180
-
-
Mastroeni, D.1
Grover, A.2
Delvaux, E.3
Whiteside, C.4
Coleman, P.D.5
Rogers, J.6
-
46
-
-
78651479525
-
HDAC3 is a critical negative regulator of long-term memory formation
-
doi: 10.1523/JNEUROSCI.5052-10.2011
-
Mcquown, S. C., Barrett, R. M., Matheos, D. P., Post, R. J., Rogge, G. A., Alenghat, T., et al. (2011). HDAC3 is a critical negative regulator of long-term memory formation. J. Neurosci. 31, 764-774. doi: 10.1523/JNEUROSCI.5052-10.2011
-
(2011)
J. Neurosci.
, vol.31
, pp. 764-774
-
-
Mcquown, S.C.1
Barrett, R.M.2
Matheos, D.P.3
Post, R.J.4
Rogge, G.A.5
Alenghat, T.6
-
47
-
-
77957001697
-
-
doi: 10.1016/j.neuron.2010.08.044
-
Min, S. W., Cho, S. H., Zhou, Y., Schroeder, S., Haroutunian, V., Seeley, W. W., et al. (2010). Acetylation of tau inhibits its degradation and contributes to tauopathy. Neuron 67, 953-966. doi: 10.1016/j.neuron.2010.08.044
-
(2010)
Acetylation of tau inhibits its degradation and contributes to tauopathy. Neuron
, vol.67
, pp. 953-966
-
-
Min, S.W.1
Cho, S.H.2
Zhou, Y.3
Schroeder, S.4
Haroutunian, V.5
Seeley, W.W.6
-
48
-
-
84858157217
-
The senescence accelerated mouse (SAMP8) as a model for oxidative stress and Alzheimer's disease
-
doi: 10.1016/j.bbadis.2011.11.015
-
Morley, J. E., Armbrecht, H. J., Farr, S. A., and Kumar, V. B. (2012a). The senescence accelerated mouse (SAMP8) as a model for oxidative stress and Alzheimer's disease. Biochim. Biophys. Acta 1822, 650-656. doi: 10.1016/j.bbadis.2011.11.015
-
(2012)
Biochim. Biophys. Acta
, vol.1822
, pp. 650-656
-
-
Morley, J.E.1
Armbrecht, H.J.2
Farr, S.A.3
Kumar, V.B.4
-
49
-
-
84857125516
-
The SAMP8 mouse: a model to develop therapeutic interventions for Alzheimer's disease
-
doi: 10.2174/138161212799315795
-
Morley, J. E., Farr, S. A., Kumar, V. B., and Armbrecht, H. J. (2012b). The SAMP8 mouse: a model to develop therapeutic interventions for Alzheimer's disease. Curr. Pharm. Des. 18, 1123-1130. doi: 10.2174/138161212799315795
-
(2012)
Curr. Pharm. Des.
, vol.18
, pp. 1123-1130
-
-
Morley, J.E.1
Farr, S.A.2
Kumar, V.B.3
Armbrecht, H.J.4
-
50
-
-
80053103560
-
-
doi: 10.1002/hipo.20822
-
Muller, A. P., Gnoatto, J., Moreira, J. D., Zimmer, E. R., Haas, C. B., Lulhier, F., et al. (2011). Exercise increases insulin signaling in the hippocampus: physiological effects and pharmacological impact of intracerebroventricular insulin administration in mice. Hippocampus 21, 1082-1092. doi: 10.1002/hipo.20822
-
(2011)
Exercise increases insulin signaling in the hippocampus: physiological effects and pharmacological impact of intracerebroventricular insulin administration in mice. Hippocampus
, vol.21
, pp. 1082-1092
-
-
Muller, A.P.1
Gnoatto, J.2
Moreira, J.D.3
Zimmer, E.R.4
Haas, C.B.5
Lulhier, F.6
-
51
-
-
58149380018
-
From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8)
-
Pallas, M., Camins, A., Smith, M. A., Perry, G., Lee, H. G., and Casadesus, G. (2008a). From aging to Alzheimer's disease: unveiling "the switch" with the senescence-accelerated mouse model (SAMP8). J. Alzheimers Dis. 15, 615-624.
-
(2008)
J. Alzheimers Dis.
, vol.15
, pp. 615-624
-
-
Pallas, M.1
Camins, A.2
Smith, M.A.3
Perry, G.4
Lee, H.G.5
Casadesus, G.6
-
52
-
-
45849121349
-
-
doi: 10.1016/j.neuroscience.2008.04.065
-
Pallas, M., Pizarro, J. G., Gutierrez-Cuesta, J., Crespo-Biel, N., Alvira, D., Tajes, M., et al. (2008b). Modulation of SIRT1 expression in different neurodegenerative models and human pathologies. Neuroscience 154, 1388-1397. doi: 10.1016/j.neuroscience.2008.04.065
-
(2008)
Modulation of SIRT1 expression in different neurodegenerative models and human pathologies. Neuroscience
, vol.154
, pp. 1388-1397
-
-
Pallas, M.1
Pizarro, J.G.2
Gutierrez-Cuesta, J.3
Crespo-Biel, N.4
Alvira, D.5
Tajes, M.6
-
53
-
-
33644946604
-
HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis
-
doi: 10.1038/sj.cdd.4401769
-
Saha, R. N., and Pahan, K. (2006). HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis. Cell Death Differ. 13, 539-550. doi: 10.1038/sj.cdd.4401769
-
(2006)
Cell Death Differ
, vol.13
, pp. 539-550
-
-
Saha, R.N.1
Pahan, K.2
-
54
-
-
83055170106
-
Involvement of leucine zipper transcription factor-like protein 1 (Lztfl1) in the attenuation of cognitive impairment by exercise training
-
doi: 10.1016/j.bbrc.2011.11.008
-
Sakurai, T., Ogasawara, J., Kizaki, T., Ishibashi, Y., Fujiwara, T., Akagawa, K., et al. (2011). Involvement of leucine zipper transcription factor-like protein 1 (Lztfl1) in the attenuation of cognitive impairment by exercise training. Biochem. Biophys. Res. Commun. 416, 125-129. doi: 10.1016/j.bbrc.2011.11.008
-
(2011)
Biochem. Biophys. Res. Commun.
, vol.416
, pp. 125-129
-
-
Sakurai, T.1
Ogasawara, J.2
Kizaki, T.3
Ishibashi, Y.4
Fujiwara, T.5
Akagawa, K.6
-
56
-
-
34247611481
-
-
doi: 10.1212/01.wnl.0000260698.46517.8f
-
Scheff, S. W., Price, D. A., Schmitt, F. A., Dekosky, S. T., and Mufson, E. J. (2007). Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment. Neurology 68, 1501-1508. doi: 10.1212/01.wnl.0000260698.46517.8f
-
(2007)
Synaptic alterations in CA1 in mild Alzheimer disease and mild cognitive impairment. Neurology
, vol.68
, pp. 1501-1508
-
-
Scheff, S.W.1
Price, D.A.2
Schmitt, F.A.3
Dekosky, S.T.4
Mufson, E.J.5
-
57
-
-
0035900626
-
-
doi: 10.1016/S0306-4522(01)00315-3
-
Shen, H., Tong, L., Balazs, R., and Cotman, C. W. (2001). Physical activity elicits sustained activation of the cyclic AMP response element-binding protein and mitogen-activated protein kinase in the rat hippocampus. Neuroscience 107, 219-229. doi: 10.1016/S0306-4522(01)00315-3
-
(2001)
Physical activity elicits sustained activation of the cyclic AMP response element-binding protein and mitogen-activated protein kinase in the rat hippocampus. Neuroscience
, vol.107
, pp. 219-229
-
-
Shen, H.1
Tong, L.2
Balazs, R.3
Cotman, C.W.4
-
58
-
-
76249126432
-
Polycomb repressive complex 2 and trithorax modulate drosophila longevity and stress resistance
-
doi: 10.1073/pnas.0907739107
-
Siebold, A. P., Banerjee, R., Tie, F., Kiss, D. L., Moskowitz, J., and Harte, P. J. (2010). Polycomb repressive complex 2 and trithorax modulate drosophila longevity and stress resistance. Proc. Natl. Acad. Sci. U.S.A. 107, 169-174. doi: 10.1073/pnas.0907739107
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 169-174
-
-
Siebold, A.P.1
Banerjee, R.2
Tie, F.3
Kiss, D.L.4
Moskowitz, J.5
Harte, P.J.6
-
59
-
-
84872982286
-
HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs? Mol
-
doi: 10.1186/1750-1326-8-7
-
Simoes-Pires, C., Zwick, V., Nurisso, A., Schenker, E., Carrupt, P. A., and Cuendet, M. (2013). HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs? Mol. Neurodegener. 8:7. doi: 10.1186/1750-1326-8-7
-
(2013)
Neurodegener
, vol.8
-
-
Simoes-Pires, C.1
Zwick, V.2
Nurisso, A.3
Schenker, E.4
Carrupt, P.A.5
Cuendet, M.6
-
60
-
-
62349123068
-
-
doi: 10.1007/s11064-009-9922-y
-
Takeda, T. (2009). Senescence-accelerated mouse (SAM) with special references to neurodegeneration models, SAMP8 and SAMP10 mice. Neurochem. Res. 34, 639-659. doi: 10.1007/s11064-009-9922-y
-
(2009)
, vol.34
, pp. 639-659
-
-
Takeda, T.1
-
61
-
-
0025938219
-
Senescence-accelerated mouse (SAM): a novel murine model of accelerated senescence
-
Takeda, T., Hosokawa, M., and Higuchi, K. (1991). Senescence-accelerated mouse (SAM): a novel murine model of accelerated senescence. J. Am. Geriatr. Soc. 39, 911-919.
-
(1991)
J. Am. Geriatr. Soc.
, vol.39
, pp. 911-919
-
-
Takeda, T.1
Hosokawa, M.2
Higuchi, K.3
-
62
-
-
84878107240
-
Epigenetics: the link between nature and nurture
-
doi: 10.1016/j.mam.2012.07.018
-
Tammen, S. A., Friso, S., and Choi, S. W. (2013). Epigenetics: the link between nature and nurture. Mol. Aspects Med. 34, 753-764. doi: 10.1016/j.mam.2012.07.018
-
(2013)
Mol. Aspects Med.
, vol.34
, pp. 753-764
-
-
Tammen, S.A.1
Friso, S.2
Choi, S.W.3
-
63
-
-
0035664114
-
Effects of exercise on gene-expression profile in the rat hippocampus
-
doi: 10.1006/nbdi.2001.0427
-
Tong, L., Shen, H., Perreau, V. M., Balazs, R., and Cotman, C. W. (2001). Effects of exercise on gene-expression profile in the rat hippocampus. Neurobiol. Dis. 8, 1046-1056. doi: 10.1006/nbdi.2001.0427
-
(2001)
Neurobiol. Dis.
, vol.8
, pp. 1046-1056
-
-
Tong, L.1
Shen, H.2
Perreau, V.M.3
Balazs, R.4
Cotman, C.W.5
-
64
-
-
38649115676
-
The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis
-
doi: 10.1016/j.mcn.2007.10.016
-
Trejo, J. L., Llorens-Martin, M. V., and Torres-Aleman, I. (2008). The effects of exercise on spatial learning and anxiety-like behavior are mediated by an IGF-I-dependent mechanism related to hippocampal neurogenesis. Mol. Cell. Neurosci. 37, 402-411. doi: 10.1016/j.mcn.2007.10.016
-
(2008)
Mol. Cell. Neurosci.
, vol.37
, pp. 402-411
-
-
Trejo, J.L.1
Llorens-Martin, M.V.2
Torres-Aleman, I.3
-
65
-
-
84891371158
-
Epigenetically regulated microRNAs in Alzheimer's disease
-
doi: 10.1016/j.neurobiolaging.2013.10.082
-
Van Den Hove, D. L., Kompotis, K., Lardenoije, R., Kenis, G., Mill, J., Steinbusch, H. W., et al. (2014). Epigenetically regulated microRNAs in Alzheimer's disease. Neurobiol. Aging 35, 731-745. doi: 10.1016/j.neurobiolaging.2013.10.082
-
(2014)
Neurobiol. Aging
, vol.35
, pp. 731-745
-
-
Van Den Hove, D.L.1
Kompotis, K.2
Lardenoije, R.3
Kenis, G.4
Mill, J.5
Steinbusch, H.W.6
-
66
-
-
84896822801
-
Age-related alterations in the metabolic profile in the hippocampus of the senescence-accelerated mouse prone 8 a spontaneous Alzheimer's disease mouse model
-
doi: 10.3233/JAD-131463
-
Wang, H., Lian, K., Han, B., Wang, Y., Kuo, S. H., Geng, Y., et al. (2013). Age-related alterations in the metabolic profile in the hippocampus of the senescence-accelerated mouse prone 8: a spontaneous Alzheimer's disease mouse model. J. Alzheimers Dis. 39, 841-848. doi: 10.3233/JAD-131463
-
(2013)
J. Alzheimers Dis.
, vol.39
, pp. 841-848
-
-
Wang, H.1
Lian, K.2
Han, B.3
Wang, Y.4
Kuo, S.H.5
Geng, Y.6
-
67
-
-
84866371474
-
MicroRNAs in learning, memory, and neurological diseases
-
doi: 10.1101/lm.026492.112
-
Wang, W., Kwon, E. J., and Tsai, L. H. (2012). MicroRNAs in learning, memory, and neurological diseases. Learn. Mem. 19, 359-368. doi: 10.1101/lm.026492.112
-
(2012)
Learn. Mem.
, vol.19
, pp. 359-368
-
-
Wang, W.1
Kwon, E.J.2
Tsai, L.H.3
-
68
-
-
79451474371
-
Patterns of microRNA expression in normal and early Alzheimer's disease human temporal cortex: white matter versus gray matter
-
doi: 10.1007/s00401-010-0756-0
-
Wang, W. X., Huang, Q., Hu, Y., Stromberg, A. J., and Nelson, P. T. (2011). Patterns of microRNA expression in normal and early Alzheimer's disease human temporal cortex: white matter versus gray matter. Acta Neuropathol. 121, 193-205. doi: 10.1007/s00401-010-0756-0
-
(2011)
Acta Neuropathol
, vol.121
, pp. 193-205
-
-
Wang, W.X.1
Huang, Q.2
Hu, Y.3
Stromberg, A.J.4
Nelson, P.T.5
-
69
-
-
42949086521
-
Approaches for studying microRNA and small interfering RNA methylation in vitro and in vivo
-
doi: 10.1016/S0076-6879(07)27008-9
-
Yang, Z., Vilkaitis, G., Yu, B., Klimasauskas, S., and Chen, X., (2007). Approaches for studying microRNA and small interfering RNA methylation in vitro and in vivo. Methods Enzymol. 427, 139-154. doi: 10.1016/S0076-6879(07)27008-9
-
(2007)
Methods Enzymol
, vol.427
, pp. 139-154
-
-
Yang, Z.1
Vilkaitis, G.2
Yu, B.3
Klimasauskas, S.4
Chen, X.5
|