Differential role of melatonin in restoration of age-induced alterations in daily rhythms of expression of various clock genes in suprachiasmatic nucleus of male Wistar rats

Biogerontology

Volumn 15, Issue 3, 2014, Pages 257-268

  Mattam, Ushodaya ^a   Jagota, Anita ^a  

^a UNIVERSITY OF HYDERABAD   (India)

Author keywords

Aging; Circadian rhythms; Clock genes; Melatonin; Suprachiasmatic nucleus

Indexed keywords

COMPLEMENTARY DNA; MELATONIN; MESSENGER RNA; ANTIOXIDANT; CIRCADIAN RHYTHM SIGNALING PROTEIN; CRY1 PROTEIN, RAT; CRY2 PROTEIN, RAT; CRYPTOCHROME; MORPHINAN DERIVATIVE; MR 1257 MS; PER1 PROTEIN, RAT; PER2 PROTEIN, RAT; TRANSCRIPTION FACTOR ARNTL;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; DNA SYNTHESIS; GENE; GENE AMPLIFICATION; GENE EXPRESSION; MALE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; RBMAL1 GENE; RCRY1 GENE; RCRY2 GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; RPER1 GENE; RPER2 GENE; STOICHIOMETRY; SUPRACHIASMATIC NUCLEUS; ANIMAL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; WISTAR RAT;

AGING; ANIMALS; ANTIOXIDANTS; ARNTL TRANSCRIPTION FACTORS; CIRCADIAN RHYTHM; CIRCADIAN RHYTHM SIGNALING PEPTIDES AND PROTEINS; CRYPTOCHROMES; GENE EXPRESSION REGULATION; MALE; MELATONIN; MORPHINANS; PERIOD CIRCADIAN PROTEINS; RATS, WISTAR; SUPRACHIASMATIC NUCLEUS;

EID: 84901344165     PISSN: 13895729     EISSN: 15736768     Source Type: Journal    
DOI: 10.1007/s10522-014-9495-2     Document Type: Article

References (52)

1. Abe H, Honma S, Namihira M, Tanahashi Y, Ikeda M, Honma K (1998) Circadian rhythm and light responsiveness of BMAL1 expression, a partner of mammalian clock gene Clock, in the suprachiasmatic nucleus of rats. Neurosci Lett 258:93-96 (Pubitemid 28566182)
2. Agez L, Laurent V, Guerrero YH, Pevet P, Masson-Pevet M, Gauer F (2009) Endogenous melatonin provides an effective circadian message to both the suprachiasmatic nuclei pars tuberalis of the rat. J Pineal Res 46:95-105
3. Arendt J (2005) Melatonin: characteristics, concerns, and prospects. J Biol Rhythms 20:291-303
4. Armstrong SM, Redman JR (1991) Melatonin: a chronobiotic with anti-aging properties? Med Hypotheses 34:300-309
5. Biello MS (2009) Circadian clock resetting in the mouse changes with age. AGE 31:293-303
6. Bunger MK, Wilsbacher LD, Moran SM, Clendenin C, Radcliffe LA, Hogenesch JB, Simon MC, Takahashi JS, Bradfield CA (2000) Mop3 is an essential component of the master circadian pacemaker in mammals. Cell 103: 1009-1017 (Pubitemid 32037390)
7. Cassone VM, Roberts HM, Moore YR (1987) Melatonin inhibits metabolic activity in the rat suprachiasmatic nuclei. Neurosci Lett 81:29-34 (Pubitemid 17145529)
8. Chomczynski P, Sacchi N (2006) Single-step method of RNA isolation by acid guanidinium thiocyanatephenol-chloroform extraction: twenty-something years on. Nat Protoc 1:581-585
9. Dubocovich ML, Markowska M (2005) Functional MT1 and MT2 melatonin receptors in mammals. Endocrine 27:101-110 (Pubitemid 41558442)
10. Duncan MJ, Prochot JR, Cook DH, Tyler SJ, Franklin KM (2013) Influence of aging on Bmal1 and Per2 expression in extra - SCN oscillators in hamster brain. Brain Res 1491:44-53
11. Farajnia S, Michel S, Deboer T, Vanderleest HT, Houben T, Rohling JH, Ramkisoensing A, Yasenkov R, Meijer JH (2012) Evidence for neuronal desynchrony in the aged suprachiasmatic nucleus clock. J Neurosci 32:5891-5899
12. Garau C, Aparicio S, Rial VR, Nicolau CM, Esteban S (2006) Age related changes in the activity-rest circadian rhythms and c-fos expression of ring doves with aging. Effects of tryptophan intake. Exp Gerontol 41:430-438
13. Hofman MA, Swaab DF (2006) Living by the clock: the circadian pacemaker in older people. Ageing Res Rev 5:33-51 (Pubitemid 43139666)
14. Hurd MW, Ralph MR (1998) The significance of circadian organization for longevity in the golden hamster. J Biol Rhythms 13:430-436 (Pubitemid 128478940)
15. Jagota A (2012) Age-induced alterations in biological clock: therapeutic effects of melatonin. In: Thakur MK, Rattan SIS (eds) Brain aging and therapeutic interventions. Springer, Netherlands, London, pp 111-129
16. Jagota A, Kalyani D (2010) Effect of melatonin on age induced changes in daily serotonin rhythms in suprachiasmatic nucleus of male wistar rat. Biogerontology 11:299-308
17. Jagota A, Reddy MY (2007) The effect of Curcumin on ethanol induced changes in Suprachiasmatic nucleus (SCN) and Pineal. Cell Mol Neurobiol 27:997-1006 (Pubitemid 351170073)
18. Jin X, von Gall C, Pieschl RL, Gribkoff VK, Stehle JH, Reppert SM, Weaver DR (2003) Targeted disruption of the mouse Mel(1b) melatonin receptor. Mol Cell Biol 23:1054-1060 (Pubitemid 36133521)
19. Kamphuis W, Cailotto C, Dijk F, Bergen A, Buijs RM (2005) Circadian expression of clock genes and clock-controlled genes in the rat retina. Biochem Biophys Res Commun 330:18-26 (Pubitemid 40394930)
20. Karasek M (2004) Melatonin, human aging, and age-related diseases. Exp Gerontol 39:1723-1729
21. Ko HC, Takahashi SJ (2006) Molecular components of circadian clock. Hum Mol Genet 15:271-277
22. Kolker DE, Olson SL, Dutton-Boilek J, Bennett KM, Wallen EP (2002) Feeding melatonin enhances the phase shifting response to triazolam in both young and old golden hamsters. Am J Physiol 282:1382-1388
23. Kolker DE, Fukuyama H, Huang DS, Takahashi JS, Horton TH, Turek FW (2003) Aging alters circadian and light-induced expression of clock genes in golden hamsters. J Biol Rhythms 18:159-169 (Pubitemid 37187300)
24. Kondratov VR, Vykhovanets O, Kondratova AA, Antoch PM (2009) Antioxidant N-acetyl-L-cysteine ameliorates symptoms of premature aging associated with the deficiency of the circadian protein BMAL1. Aging 1:979-987
25. Kondrotov RV, Kondrotova AA, Gorbacheva VY, Vychovanets OV, Antoch MP (2006) Early aging and age related pathologies in mice deficient in BMAL1, the core component of the circadian clock. Genes Dev 20:1868-1873 (Pubitemid 44088348)
26. Kunieda T, Minamino T, Katsuno T, Tateno K, Nishi J, Miyauchi H, Orimo M, Okada S, Komuro I (2006) Cellular senescence impairs circadian expression of clock genes in vitro and in vivo. Circ Res 3:532-539
27. Liu C, Weaver DR, Jin X, Shearman LP, Pieschl RL, Gribkoff VK, Reppert SM (1997) Molecular dissection of two distinct actions of melatonin on the suprachiasmatic circadian clock. Neuron 19:91-102 (Pubitemid 27332996)
28. Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2-ΔΔ Ct Method. Methods 25:402-408 (Pubitemid 34164012)
29. Manikonda PK, Jagota A (2012) Melatonin administration differentially affects age-induced alterations in daily rhythms of lipid peroxidation and antioxidant enzymes in male rat liver. Biogerentology 13:511-524
30. Mohawk JA, Green CB, Takahashi JS (2012) Central and peripheral circadian clocks in mammals. Annu Rev Neurosci 35:445-462
31. Muradian KK, Utko NA, Mozzhukhina TG, Litoshenko AY, Pishel IN, Bezrukov VV, Fraifield VE (2002) Pair-wise linear and 3D nonlinear relationships between the liver antioxidant enzyme activities and the rate of body oxygen consumption in mice. Free Radic Biol Med 33:1736-1739 (Pubitemid 35462013)
32. Nakamura JT, Nakamura W, Yamazaki S, Kudo T, Cutler T, Colwell CS, Block GD (2011) Age-related decline in circadian output. J Neurosci 31:10201-10205
33. Palomba M, Nygard M, Florenzano F, Bertini G, Kristenssion K, Bentivoglio M (2008) Decline of the presynaptic network, including GABAergic terminals, in the aging suprachiasmatic nucleus of the mouse. J Biol Rhythms 23:220-231 (Pubitemid 351652373)
34. Park K, Kang MH (2004) Cloning and circadian expression of Rat Cry1. Mol Cells 18:256-260 (Pubitemid 40081222)
35. Pazo D, Cardinali DP, Cano P, Reyes Toso CA, Esquifino AI (2002) Age-related changes in 24-hour rhythms of norepinephrine content and serotonin turnover in rat pineal gland: effect of melatonin treatment. Neurosignals 11:81-87
36. Poeggeler B (2005) Melatonin, aging, and age-related diseases: perspectives for prevention, intervention, and therapy. Endocrine 27:201-212
37. Poirel VJ, Boggio V, Dardente H, Pevet P, Masson-Pevet M, Gauer F (2003) Contrary to other non-photic cues, acute melatonin injection does not induce immediate change of clock gene mRNA expression in the rat suprachiasmatic nuclei. Neuroscience 120:745-755 (Pubitemid 36928071)
38. Reiter RJ, Tan DX, Fuentes-Broto L (2010) Melatonin: a multitasking molecule. Prog Brain Res 181:127-151
39. Robles MS, Boyault C, Knutti D, Padmanabhan K, Weitz CJ (2010) Identification of RACK1 and protein kinase C alpha as integral components of the mammalian circadian clock. Science 327:463-466
40. Sanchez-Hidalgo M, de la Lastra CA, Carrascosa-Salmoral MP, Naranjo MC, Gomez-Corvera A, Caballero B, Guerrero JM (2009) Age-related changes in melatonin synthesis in rat extrapineal tissues. Exp Gerontol 44:328-334
41. 2+-dependent protein kinase C mediates resetting of the mammalian circadian clock. EMBO Rep 8:366-371
42. Shimomura K, Lowrey LP, Vitaterna HM, Buhr DE, Kumar V, Hanna P, Omura C, Izumo M, Low SS, Barrett KR, LaRue IS, Green BC, Takahashi SJ (2010) Genetic suppression of the circadian clock mutation by the melatonin biosynthesis pathway. Proc Natl Acad Sci 107:8399-8403
43. Sumova A, Illnerova H (1996) Melatonin instantaneously resets intrinsic circadian rhythmicity in the rat suprachiasmatic nucleus. Neurosci Lett 218:181-184 (Pubitemid 26388845)
44. von Gall C, Weaver DR (2008) Loss of responsiveness to melatonin in the aging mouse suprchiasmatic nucleus. Neurobiol Aging 29:464-470 (Pubitemid 351215582)
45. Warren SW, Hodges BD, Cassone MV (1993) Pinealectomized rats entrain and phase-shift to melatonin injections in a dose-dependent manner. J Biol Rhythms 8:233-245
46. Weinert D (2010) Circadian temperature variation and aging. Ageing Res Rev 9:51-60
47. Weinert H, Weinert D, Schurov I, Maywood ES, Hastings MH (2001) Impaired expression of the mPer2 circadian clock gene in the suprachiasmatic nuclei of aging mice. Chronobiol Int 18:559-565 (Pubitemid 32666424)
48. Welsh KD, Takahashi SJ, Kay AS (2010) Suprachiasmatic nucleus: cell autonomy and network properties. Annu Rev Physiol 72:551-577
49. Wu Y, Swaab FD (2005) The human pineal gland and melatonin in aging and Alzheimer's disease. J Pineal Res 38:145-152 (Pubitemid 40396171)
50. Wyse AC, Coogan NA (2010) Impact of aging on diurnal expression patterns of CLOCK and BMAL1 in the mouse brain. Brain Res 1337:21-31
51. Yan ST, Shigeyoshi YT, Okamura H (1999) Per1 and Per2 gene expression in the rat suprachiasmatic nucleus: circadian profile and the compartment-specific response to light. Neuroscience 94:141-150
52. Yasuo S, Yoshimura T, Bartell AP, Iigo M, Makino E, Okabayashi N, Ebihara S (2002) Effect of melatonin administration on qPer2, qPer3, and qClock gene expression in the suprachiasmatic nucleus of Japanese quail. Eur J Neurosci 16:1541-1546 (Pubitemid 35334991)