Deacetylation of FoxO by Sirt1 plays an essential role in mediating starvation-induced autophagy in cardiac myocytes

Circulation Research

Volumn 107, Issue 12, 2010, Pages 1470-1482

  Hariharan, Nirmala ^a   Maejima, Yasuhiro ^a   Nakae, Jun ^b   Paik, Jihye ^c   Depinho, Ronald A ^c   Sadoshima, Junichi ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

autophagy; deacetylation; FoxO; Rab7; Sirt1; starvation

Indexed keywords

BECLIN 1; BINDING PROTEIN; GLUCOSE; GUANOSINE TRIPHOSPHATE; HISTONE ACETYLTRANSFERASE; PROTEIN P300; PROTEIN P62; RAB7 PROTEIN; SIRTUIN 1; TRANSCRIPTION FACTOR FKHR;

ANIMAL EXPERIMENT; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DEACETYLATION; ENZYME BLOOD LEVEL; HEART FUNCTION; HEART MUSCLE CELL; HISTONE ACETYLATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; STARVATION; UPREGULATION;

ACETYLATION; ANIMALS; AUTOPHAGY; CELLS, CULTURED; FORKHEAD TRANSCRIPTION FACTORS; MICE; MYOCYTES, CARDIAC; RAB GTP-BINDING PROTEINS; SIRTUIN 1; STARVATION; VENTRICULAR FUNCTION, LEFT;

EID: 78650691023     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.110.227371     Document Type: Article

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