A novel pathway regulates memory and plasticity via SIRT1 and miR-134

Nature

Volumn 466, Issue 7310, 2010, Pages 1105-1109

  Gao, Jun ^a,b   Wang, Wen Yuan ^a   Mao, Ying Wei ^a   Gräff, Johannes ^a,c   Guan, Ji Song ^a   Pan, Ling ^a   Mak, Gloria ^a   Kim, Dohoon ^a,d   Su, Susan C ^a   Tsai, Li Huei ^a,c  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b NANJING UNIVERSITY   (China)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^d WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MICRORNA; MIR 134; SIRTUIN 1; TRANSCRIPTION FACTOR YY1; UNCLASSIFIED DRUG;

BRAIN; CARDIOVASCULAR SYSTEM; COGNITION; DISEASE TREATMENT; DNA; EVOLUTIONARY BIOLOGY; GENE EXPRESSION; LONGEVITY; MAMMAL; MEMORY; NERVOUS SYSTEM DISORDER; NEUROLOGY; SURVIVAL; YEAST;

ANIMAL EXPERIMENT; ARTICLE; BRAIN FUNCTION; CELL SURVIVAL; COGNITION; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; GENE REPRESSION; MALE; MEMORY; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR DOWN REGULATION; SIGNAL TRANSDUCTION;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CREB-BINDING PROTEIN; ELECTRICAL SYNAPSES; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; LONG-TERM POTENTIATION; MALE; MEMORY; MEMORY DISORDERS; MICE; MICRORNAS; NEURONAL PLASTICITY; PROTEIN BINDING; SEQUENCE DELETION; SIRTUIN 1;

MAMMALIA; SACCHAROMYCETALES;

EID: 77956185062     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature09271     Document Type: Article

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