Leptin boosts cellular metabolism by activating AMPK and the sirtuins to reduce tau phosphorylation and β-amyloid in neurons

Biochemical and Biophysical Research Communications

Volumn 414, Issue 1, 2011, Pages 170-174

  Greco, Steven J ^a   Hamzelou, Ashkan ^a   Johnston, Jane M ^a   Smith, Mark A ^b   Ashford, J Wesson ^c   Tezapsidis, Nikolaos ^a  

^a Neurotez Inc   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VA PALO ALTO HEALTH CARE SYSTEM   (United States)

Author keywords

Amyloid; Alzheimer's; AMPK; Leptin; SIRT; Tau

Indexed keywords

AMYLOID BETA PROTEIN; LEPTIN; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE; SIRTUIN; TAU PROTEIN;

ALZHEIMER DISEASE; ARTICLE; BIOLOGICAL ACTIVITY; CELL METABOLISM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IN VITRO STUDY; NERVE CELL; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PEPTIDES; CELL LINE, TUMOR; ENZYME ACTIVATION; HUMANS; LEPTIN; NEURONS; PHOSPHORYLATION; PROTEIN KINASES; SIRTUINS; TAU PROTEINS;

EID: 80054072264     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.09.050     Document Type: Article

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