메뉴 건너뛰기




Volumn 6, Issue 4, 2004, Pages 463-477

Development by self-digestion: Molecular mechanisms and biological functions of autophagy

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; FUNGAL PROTEIN; GUANOSINE TRIPHOSPHATASE; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; RAPAMYCIN; RAS PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; TARGET OF RAPAMYCIN KINASE; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN;

EID: 1842583789     PISSN: 15345807     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1534-5807(04)00099-1     Document Type: Review
Times cited : (3395)

References (112)
  • 1
    • 1842419925 scopus 로고    scopus 로고
    • Regulation of autophagy by the Target of Rapamycin (Tor) proteins
    • D. J. Klionsky (Ed.), Georgetown, TX: Landes Bioscience
    • Abeliovich H. Regulation of autophagy by the Target of Rapamycin (Tor) proteins In Klionsky D.J. (Ed.), Autophagy 2004 60-69 Landes Bioscience Georgetown, TX
    • (2004) Autophagy , pp. 60-69
    • Abeliovich, H.1
  • 3
    • 0023902842 scopus 로고
    • Mutants of Caenorhabditis elegans that form dauer-like larvae
    • Albert P.S. Riddle D.L. Mutants of Caenorhabditis elegans that form dauer-like larvae Dev. Biol. 126 1988 270-293
    • (1988) Dev. Biol. , vol.126 , pp. 270-293
    • Albert, P.S.1    Riddle, D.L.2
  • 4
    • 0017839317 scopus 로고
    • Role of the vacuolar apparatus in augmented protein degradation in cultured fibroblasts
    • Amenta J.S. Sargus M.J. Venkatesan S. Shinozuka H. Role of the vacuolar apparatus in augmented protein degradation in cultured fibroblasts J. Cell. Physiol. 94 1978 77-86
    • (1978) J. Cell. Physiol. , vol.94 , pp. 77-86
    • Amenta, J.S.1    Sargus, M.J.2    Venkatesan, S.3    Shinozuka, H.4
  • 5
    • 0035929650 scopus 로고    scopus 로고
    • The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway
    • Arico S. Petiot A. Bauvy C. Dubbelhuis P.F. Meijer A.J. Codogno P. Ogier-Denis E. The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase/protein kinase B pathway J. Biol. Chem. 276 2001 35243-35246
    • (2001) J. Biol. Chem. , vol.276 , pp. 35243-35246
    • Arico, S.1    Petiot, A.2    Bauvy, C.3    Dubbelhuis, P.F.4    Meijer, A.J.5    Codogno, P.6    Ogier-Denis, E.7
  • 6
    • 0041411115 scopus 로고    scopus 로고
    • Autophagic programmed cell death in Drosophila
    • Baehrecke E.H. Autophagic programmed cell death in Drosophila Cell Death Differ. 10 2003 940-945
    • (2003) Cell Death Differ. , vol.10 , pp. 940-945
    • Baehrecke, E.H.1
  • 7
    • 0043204997 scopus 로고    scopus 로고
    • The anti-ageing effects of caloric restriction may involve stimulation of macroautophagy and lysosomal degradation, and can be intensified pharmacologically
    • Bergamini E. Cavallini G. Donati A. Gori Z. The anti-ageing effects of caloric restriction may involve stimulation of macroautophagy and lysosomal degradation, and can be intensified pharmacologically Biomed. Pharmacother. 57 2003 203-208
    • (2003) Biomed. Pharmacother. , vol.57 , pp. 203-208
    • Bergamini, E.1    Cavallini, G.2    Donati, A.3    Gori, Z.4
  • 8
    • 0035902180 scopus 로고    scopus 로고
    • Oncogenic kinase signalling
    • Blume-Jensen P. Hunter T. Oncogenic kinase signalling Nature 411 2001 355-365
    • (2001) Nature , vol.411 , pp. 355-365
    • Blume-Jensen, P.1    Hunter, T.2
  • 9
    • 0035499454 scopus 로고    scopus 로고
    • Ten years of protein kinase B signalling: A hard Akt to follow
    • Brazil D.P. Hemmings B.A. Ten years of protein kinase B signalling: a hard Akt to follow Trends Biochem. Sci. 26 2001 657-664
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 657-664
    • Brazil, D.P.1    Hemmings, B.A.2
  • 10
    • 0034948738 scopus 로고    scopus 로고
    • The autophagosomal-lysosomal compartment in programmed cell death
    • Bursch W. The autophagosomal-lysosomal compartment in programmed cell death Cell Death Differ. 8 2001 569-581
    • (2001) Cell Death Differ. , vol.8 , pp. 569-581
    • Bursch, W.1
  • 11
    • 1842524534 scopus 로고    scopus 로고
    • Autophagocytosis and programmed cell death
    • D. J. Klionsky (Ed.), Georgetown, TX: Landes Bioscience
    • Bursch W. Ellinger A. Gerner C. Schultze-Hermann R. Autophagocytosis and programmed cell death In Klionsky D.J. (Ed.), Autophagy 2004 287-303 Landes Bioscience Georgetown, TX
    • (2004) Autophagy , pp. 287-303
    • Bursch, W.1    Ellinger, A.2    Gerner, C.3    Schultze-Hermann, R.4
  • 12
    • 0025283961 scopus 로고
    • Developmental cell death: Morphological diversity and multiple mechanisms
    • Clarke P.G. Developmental cell death: morphological diversity and multiple mechanisms Anat. Embryol. (Berl.) 181 1990 195-213
    • (1990) Anat. Embryol. (Berl.) , vol.181 , pp. 195-213
    • Clarke, P.G.1
  • 13
    • 0345825057 scopus 로고    scopus 로고
    • Signaling pathways in mammalian autophagy
    • D. J. Klionsky (Ed.), Georgetown, TX: Landes Bioscience
    • Codogno P. Meijer A.J. Signaling pathways in mammalian autophagy In Klionsky D.J. (Ed.), Autophagy 2004 26-47 Landes Bioscience Georgetown, TX
    • (2004) Autophagy , pp. 26-47
    • Codogno, P.1    Meijer, A.J.2
  • 14
    • 0031053972 scopus 로고    scopus 로고
    • Programmed cell death of the prothoracic glands of Manduca sexta during pupal-adult metamorphosis
    • Dai J.D. Gilbert L.I. Programmed cell death of the prothoracic glands of Manduca sexta during pupal-adult metamorphosis Insect Biochem. Mol. Biol. 27 1997 69-78
    • (1997) Insect Biochem. Mol. Biol. , vol.27 , pp. 69-78
    • Dai, J.D.1    Gilbert, L.I.2
  • 15
    • 0037180491 scopus 로고    scopus 로고
    • Parallel phenotypic analysis of sporulation and postgermination growth in Saccharomyces cerevisiae
    • Deutschbauer A.M. Williams R.M. Chiu A.M. Davis R.W. Parallel phenotypic analysis of sporulation and postgermination growth in Saccharomyces cerevisiae Proc. Natl. Acad. Sci. USA 99 2002 15530-15535
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 15530-15535
    • Deutschbauer, A.M.1    Williams, R.M.2    Chiu, A.M.3    Davis, R.W.4
  • 16
    • 0037031843 scopus 로고    scopus 로고
    • The APG8/12-activating enzyme APG7 is required for proper nutrient recycling and sensescence in Arabidopsis thaliana
    • Doelling J.H. Walker J.M. Friedman E.M. Thompson A.R. Vierstra R.D. The APG8/12-activating enzyme APG7 is required for proper nutrient recycling and sensescence in Arabidopsis thaliana J. Biol. Chem. 277 2002 33105-33114
    • (2002) J. Biol. Chem. , vol.277 , pp. 33105-33114
    • Doelling, J.H.1    Walker, J.M.2    Friedman, E.M.3    Thompson, A.R.4    Vierstra, R.D.5
  • 17
    • 0032969092 scopus 로고    scopus 로고
    • Bacillus subtilis spore coat
    • Driks A. Bacillus subtilis spore coat Microbiol. Mol. Biol. Rev. 63 1999 1-20
    • (1999) Microbiol. Mol. Biol. Rev. , vol.63 , pp. 1-20
    • Driks, A.1
  • 18
    • 0028222874 scopus 로고
    • Autophagy and related mechanisms of lysosome-mediated protein degradation
    • Dunn W.A.J. Autophagy and related mechanisms of lysosome-mediated protein degradation Trends Cell Biol. 4 1994 139-143
    • (1994) Trends Cell Biol. , vol.4 , pp. 139-143
    • Dunn, W.A.J.1
  • 20
    • 0035487007 scopus 로고    scopus 로고
    • The mitochondrial permeability transition initiates autophagy in rat hepatocytes
    • Elmore S.P. Qian T. Grissom S.F. Lemasters J.J. The mitochondrial permeability transition initiates autophagy in rat hepatocytes FASEB J. 15 2001 2286-2287
    • (2001) FASEB J. , vol.15 , pp. 2286-2287
    • Elmore, S.P.1    Qian, T.2    Grissom, S.F.3    Lemasters, J.J.4
  • 21
    • 1842419926 scopus 로고    scopus 로고
    • Structural aspects of mammalian autophagy
    • D. J. Klionsky (Ed.), Georgetown, TX: Landes Bioscience
    • Fengsrud M. Sneve M.L. Overbye A. Seglen P.O. Structural aspects of mammalian autophagy In Klionsky D.J. (Ed.), Autophagy 2004 11-25 Landes Bioscience Georgetown, TX
    • (2004) Autophagy , pp. 11-25
    • Fengsrud, M.1    Sneve, M.L.2    Overbye, A.3    Seglen, P.O.4
  • 22
    • 1842524536 scopus 로고    scopus 로고
    • Autophagy and Cancer
    • D. J. Klionsky (Ed.), Georgetown, TX: Landes Bioscience
    • Furuya N. Liang X.H. Levine B. Autophagy and Cancer In Klionsky D.J. (Ed.) Autophagy 2004 241-255 Landes Bioscience Georgetown, TX
    • (2004) Autophagy , pp. 241-255
    • Furuya, N.1    Liang, X.H.2    Levine, B.3
  • 23
    • 0023646551 scopus 로고
    • Temperature dependence on protein degradation, autophagic sequestration and mitochondrial sugar uptake in rat hepatocytes
    • Gordon P.B. Kovacs A.L. Seglen P.O. Temperature dependence on protein degradation, autophagic sequestration and mitochondrial sugar uptake in rat hepatocytes Biochim. Biophys. Acta. 929 1987 128-133
    • (1987) Biochim. Biophys. Acta. , vol.929 , pp. 128-133
    • Gordon, P.B.1    Kovacs, A.L.2    Seglen, P.O.3
  • 25
    • 0035661648 scopus 로고    scopus 로고
    • Cvt18/Gsa12 is required for cytoplasm-to-vacuole transport, pexophagy, and autophagy in Saccharomyces cerevisiae and Pichia pastoris
    • Guan J. Stromhaug P.E. George M.D. Habibzadegah-Tari P. Bevan A. Dunn W.A. Jr. Klionsky D.J. Cvt18/Gsa12 is required for cytoplasm-to-vacuole transport, pexophagy, and autophagy in Saccharomyces cerevisiae and Pichia pastoris Mol. Biol. Cell 12 2001 3821-3838
    • (2001) Mol. Biol. Cell , vol.12 , pp. 3821-3838
    • Guan, J.1    Stromhaug, P.E.2    George, M.D.3    Habibzadegah-Tari, P.4    Bevan, A.5    Dunn Jr., W.A.6    Klionsky, D.J.7
  • 26
    • 0034626747 scopus 로고    scopus 로고
    • Genetic pathways that regulate ageing in model organisms
    • Guarente L. Kenyon C. Genetic pathways that regulate ageing in model organisms Nature 408 2000 255-262
    • (2000) Nature , vol.408 , pp. 255-262
    • Guarente, L.1    Kenyon, C.2
  • 28
    • 1842524533 scopus 로고    scopus 로고
    • Glucose-induced pexophagy in Pichia pastoris
    • D. J. Klionsky (Ed.), Georgetown, TX: Landes Bioscience
    • Habibzadegah-Tari P. Dunn W.A. Jr. Glucose-induced pexophagy in Pichia pastoris In Klionsky D.J. (Ed.), Autophagy 2004 126-139 Landes Bioscience Georgetown, TX
    • (2004) Autophagy , pp. 126-139
    • Habibzadegah-Tari, P.1    Dunn Jr., W.A.2
  • 29
    • 0035983934 scopus 로고    scopus 로고
    • Leaf senescence and starvation-induced chlorosis are accelerated by the disruption of an Arabidopsis autophagy gene
    • Hanaoka H. Noda T. Shirano Y. Kato T. Hayashi H. Shibata D. Tabata S. Ohsumi Y. Leaf senescence and starvation-induced chlorosis are accelerated by the disruption of an Arabidopsis autophagy gene Plant Physiol. 129 2002 1181-1193
    • (2002) Plant Physiol. , vol.129 , pp. 1181-1193
    • Hanaoka, H.1    Noda, T.2    Shirano, Y.3    Kato, T.4    Hayashi, H.5    Shibata, D.6    Tabata, S.7    Ohsumi, Y.8
  • 30
    • 0042206454 scopus 로고    scopus 로고
    • Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B
    • He H. Dang Y. Dai F. Guo Z. Wu J. She X. Pei Y. Chen Y. Ling W. Wu C. et al. Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B J. Biol. Chem. 278 2003 29278-29287
    • (2003) J. Biol. Chem. , vol.278 , pp. 29278-29287
    • He, H.1    Dang, Y.2    Dai, F.3    Guo, Z.4    Wu, J.5    She, X.6    Pei, Y.7    Chen, Y.8    Ling, W.9    Wu, C.10
  • 31
    • 0347695019 scopus 로고    scopus 로고
    • A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L
    • Hemelaar J. Lelyveld V.S. Kessler B.M. Ploegh H.L. A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L J. Biol. Chem. 278 2003 51841-51850
    • (2003) J. Biol. Chem. , vol.278 , pp. 51841-51850
    • Hemelaar, J.1    Lelyveld, V.S.2    Kessler, B.M.3    Ploegh, H.L.4
  • 33
    • 0041802820 scopus 로고    scopus 로고
    • Targeting mTOR signaling for cancer therapy
    • Huang S. Houghton P.J. Targeting mTOR signaling for cancer therapy Curr. Opin. Pharmacol. 3 2003 371-377
    • (2003) Curr. Opin. Pharmacol. , vol.3 , pp. 371-377
    • Huang, S.1    Houghton, P.J.2
  • 35
    • 0037193474 scopus 로고    scopus 로고
    • DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death
    • Inbal B. Bialik S. Sabanay I. Shani G. Kimchi A. DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death J. Cell Biol. 157 2002 455-468
    • (2002) J. Cell Biol. , vol.157 , pp. 455-468
    • Inbal, B.1    Bialik, S.2    Sabanay, I.3    Shani, G.4    Kimchi, A.5
  • 36
    • 0030681298 scopus 로고    scopus 로고
    • Steroid regulated programmed cell death during Drosophila metamorphosis
    • Jiang C. Baehrecke E.H. Thummmel C.S. Steroid regulated programmed cell death during Drosophila metamorphosis Development 124 1997 4673-4683
    • (1997) Development , vol.124 , pp. 4673-4683
    • Jiang, C.1    Baehrecke, E.H.2    Thummmel, C.S.3
  • 37
    • 0031445387 scopus 로고    scopus 로고
    • Protein synthesis, DNA degradation, and morphological changes during programmed cell death in labial glands of Manduca sexta
    • Jochova J. Quaglino D. Zakeri Z. Protein synthesis, DNA degradation, and morphological changes during programmed cell death in labial glands of Manduca sexta Dev. Genet. 21 1997 249-257
    • (1997) Dev. Genet. , vol.21 , pp. 249-257
    • Jochova, J.1    Quaglino, D.2    Zakeri, Z.3
  • 39
    • 0038393057 scopus 로고    scopus 로고
    • The Drosophila homolog of Aut1 is essential for autophagy and development
    • Juhasz G. Csikos G. Sinka R. Erdelyi M. Sass M. The Drosophila homolog of Aut1 is essential for autophagy and development FEBS Lett. 543 2003 154-158
    • (2003) FEBS Lett. , vol.543 , pp. 154-158
    • Juhasz, G.1    Csikos, G.2    Sinka, R.3    Erdelyi, M.4    Sass, M.5
  • 42
    • 0030608395 scopus 로고    scopus 로고
    • Structural and functional analyses of APG5, a gene involved in autophagy in yeast
    • Kametaka S. Matsuura A. Wada Y. Ohsumi Y. Structural and functional analyses of APG5, a gene involved in autophagy in yeast Gene 178 1996 139-143
    • (1996) Gene , vol.178 , pp. 139-143
    • Kametaka, S.1    Matsuura, A.2    Wada, Y.3    Ohsumi, Y.4
  • 43
    • 0032575551 scopus 로고    scopus 로고
    • Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae
    • Kametaka S. Okano T. Ohsumi M. Ohsumi Y. Apg14p and Apg6/Vps30p form a protein complex essential for autophagy in the yeast, Saccharomyces cerevisiae J. Biol. Chem. 273 1998 22284-22291
    • (1998) J. Biol. Chem. , vol.273 , pp. 22284-22291
    • Kametaka, S.1    Okano, T.2    Ohsumi, M.3    Ohsumi, Y.4
  • 44
    • 0035190026 scopus 로고    scopus 로고
    • Cellular function of phosphoinositide 3-kinases: Implications for development, immunity, homeostasis, and cancer
    • Katso R. Okkenhaug K. Ahmadi K. White S. Timms J. Waterfield M.D. Cellular function of phosphoinositide 3-kinases: implications for development, immunity, homeostasis, and cancer Annu. Rev. Cell Dev. Biol. 17 2001 615-675
    • (2001) Annu. Rev. Cell Dev. Biol. , vol.17 , pp. 615-675
    • Katso, R.1    Okkenhaug, K.2    Ahmadi, K.3    White, S.4    Timms, J.5    Waterfield, M.D.6
  • 46
    • 1842419923 scopus 로고    scopus 로고
    • Selective degradation of peroxisomes in the methylotrophic yeast Hansenula polymorpha
    • D. J. Klionsky (Ed.), Georgetown, TX: Landes Bioscience
    • Kiel J.A.K.W. Veenhuis M. Selective degradation of peroxisomes in the methylotrophic yeast Hansenula polymorpha In Klionsky D.J. (Ed.), Autophagy 2004 140-156 Landes Bioscience Georgetown, TX
    • (2004) Autophagy , pp. 140-156
    • Kiel, J.A.K.W.1    Veenhuis, M.2
  • 47
    • 0035809160 scopus 로고    scopus 로고
    • Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae
    • Kihara A. Noda T. Ishihara N. Ohsumi Y. Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae J. Cell Biol. 152 2001 519-530
    • (2001) J. Cell Biol. , vol.152 , pp. 519-530
    • Kihara, A.1    Noda, T.2    Ishihara, N.3    Ohsumi, Y.4
  • 48
    • 0032896760 scopus 로고    scopus 로고
    • Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways
    • Kim J. Dalton V.M. Eggerton K.P. Scott S.V. Klionsky D.J. Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways Mol. Biol. Cell 10 1999 1337-1351
    • (1999) Mol. Biol. Cell , vol.10 , pp. 1337-1351
    • Kim, J.1    Dalton, V.M.2    Eggerton, K.P.3    Scott, S.V.4    Klionsky, D.J.5
  • 49
    • 0037016752 scopus 로고    scopus 로고
    • Convergence of multiple autophagy and cytoplasm to vacuole targeting components to a perivacuolar membrane compartment prior to de novo vesicle formation
    • Kim J. Huang W.-P. Stromhaug P.E. Klionsky D.J. Convergence of multiple autophagy and cytoplasm to vacuole targeting components to a perivacuolar membrane compartment prior to de novo vesicle formation J. Biol. Chem. 277 2002 763-773
    • (2002) J. Biol. Chem. , vol.277 , pp. 763-773
    • Kim, J.1    Huang, W.-P.2    Stromhaug, P.E.3    Klionsky, D.J.4
  • 50
    • 0034676037 scopus 로고    scopus 로고
    • The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway
    • Kirisako T. Ichimura Y. Okada H. Kabeya Y. Mizushima N. Yoshimori T. Ohsumi M. Takao T. Noda T. Ohsumi Y. The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway J. Cell Biol. 151 2000 263-276
    • (2000) J. Cell Biol. , vol.151 , pp. 263-276
    • Kirisako, T.1    Ichimura, Y.2    Okada, H.3    Kabeya, Y.4    Mizushima, N.5    Yoshimori, T.6    Ohsumi, M.7    Takao, T.8    Noda, T.9    Ohsumi, Y.10
  • 53
    • 0035040496 scopus 로고    scopus 로고
    • Steroid regulation of autophagic programmed cell death during development
    • Lee C.Y. Baehrecke E.H. Steroid regulation of autophagic programmed cell death during development Development 128 2001 1443-1455
    • (2001) Development , vol.128 , pp. 1443-1455
    • Lee, C.Y.1    Baehrecke, E.H.2
  • 54
    • 0036387157 scopus 로고    scopus 로고
    • Steroid regulation of midgut cell death during Drosophila development
    • Lee C.-Y. Cooksey B.A.K. Baehrecke E.H. Steroid regulation of midgut cell death during Drosophila development Dev. Biol. 250 2002 101-111
    • (2002) Dev. Biol. , vol.250 , pp. 101-111
    • Lee, C.-Y.1    Cooksey, B.A.K.2    Baehrecke, E.H.3
  • 58
    • 0032582489 scopus 로고    scopus 로고
    • Extended life-span and stress resistance in the Drosophila mutant methuselah
    • Lin Y.J. Seroude L. Benzer S. Extended life-span and stress resistance in the Drosophila mutant methuselah Science 282 1998 943-946
    • (1998) Science , vol.282 , pp. 943-946
    • Lin, Y.J.1    Seroude, L.2    Benzer, S.3
  • 59
    • 0024817130 scopus 로고
    • Heterochronic genes control the stage-specific initiation and expression of the dauer larva developmental program in Caenorhabditis elegans
    • Liu Z.C. Ambros V. Heterochronic genes control the stage-specific initiation and expression of the dauer larva developmental program in Caenorhabditis elegans Genes Dev. 3 1989 2039-2049
    • (1989) Genes Dev. , vol.3 , pp. 2039-2049
    • Liu, Z.C.1    Ambros, V.2
  • 60
    • 0030983504 scopus 로고    scopus 로고
    • Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae
    • Matsuura A. Tsukada M. Wada Y. Ohsumi Y. Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae Gene 192 1997 245-250
    • (1997) Gene , vol.192 , pp. 245-250
    • Matsuura, A.1    Tsukada, M.2    Wada, Y.3    Ohsumi, Y.4
  • 61
    • 0042691506 scopus 로고    scopus 로고
    • Autophagy genes are essential for dauer development and lifespan extension in C. elegans
    • Melendez A. Talloczy Z. Seaman M. Eskelinen E.-L. Hall D.H. Levine B. Autophagy genes are essential for dauer development and lifespan extension in C. elegans Science 301 2003 1387-1391
    • (2003) Science , vol.301 , pp. 1387-1391
    • Melendez, A.1    Talloczy, Z.2    Seaman, M.3    Eskelinen, E.-L.4    Hall, D.H.5    Levine, B.6
  • 63
    • 0032545292 scopus 로고    scopus 로고
    • A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy
    • Mizushima N. Sugita H. Yoshimori T. Ohsumi Y. A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy J. Biol. Chem. 273 1998 33889-33892
    • (1998) J. Biol. Chem. , vol.273 , pp. 33889-33892
    • Mizushima, N.1    Sugita, H.2    Yoshimori, T.3    Ohsumi, Y.4
  • 64
    • 0033565655 scopus 로고    scopus 로고
    • Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway
    • Mizushima N. Noda T. Ohsumi Y. Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway EMBO J. 18 1999 3888-3896
    • (1999) EMBO J. , vol.18 , pp. 3888-3896
    • Mizushima, N.1    Noda, T.2    Ohsumi, Y.3
  • 66
    • 0037132504 scopus 로고    scopus 로고
    • Mouse Apg10 as an Apg12-conjugating enzyme: Analysis by the conjugation-mediated yeast two-hybrid method
    • Mizushima N. Yoshimori T. Ohsumi Y. Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the conjugation-mediated yeast two-hybrid method FEBS Lett. 532 2002 450-454
    • (2002) FEBS Lett. , vol.532 , pp. 450-454
    • Mizushima, N.1    Yoshimori, T.2    Ohsumi, Y.3
  • 67
    • 1542283812 scopus 로고    scopus 로고
    • In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker
    • Mizushima N. Yamamuto A. Matsui M. Yoshimori T. Ohsumi Y. In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker Mol. Biol. Cell 15 2003 1101-1111
    • (2003) Mol. Biol. Cell , vol.15 , pp. 1101-1111
    • Mizushima, N.1    Yamamuto, A.2    Matsui, M.3    Yoshimori, T.4    Ohsumi, Y.5
  • 69
    • 0242501201 scopus 로고    scopus 로고
    • Role of autophagy in developmental cell growth and death: Insights from Drosophila
    • D. J. Klionsky (Ed.), Georgetown, TX: Landes Bioscience
    • Neufeld T.P. Role of autophagy in developmental cell growth and death: insights from Drosophila In Klionsky D.J. (Ed.), Autophagy 2004 227-235 Landes Bioscience Georgetown, TX
    • (2004) Autophagy , pp. 227-235
    • Neufeld, T.P.1
  • 70
    • 0034614934 scopus 로고    scopus 로고
    • Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways
    • Noda T. Kim J. Huang W.-P. Baba M. Tokunaga C. Ohsumi Y. Klionsky D.J. Apg9p/Cvt7p is an integral membrane protein required for transport vesicle formation in the Cvt and autophagy pathways J. Cell Biol. 148 2000 465-480
    • (2000) J. Cell Biol. , vol.148 , pp. 465-480
    • Noda, T.1    Kim, J.2    Huang, W.-P.3    Baba, M.4    Tokunaga, C.5    Ohsumi, Y.6    Klionsky, D.J.7
  • 71
    • 1842419921 scopus 로고    scopus 로고
    • Macroautophagy in yeast
    • D. J. Klionsky (Ed.), Georgetown, TX: Landes Bioscience
    • Noda T. Ohsumi Y. Macroautophagy in yeast In Klionsky D.J. (Ed.), Autophagy 2004 70-83 Landes Bioscience Georgetown, TX
    • (2004) Autophagy , pp. 70-83
    • Noda, T.1    Ohsumi, Y.2
  • 72
    • 0016281403 scopus 로고
    • Developmental cytology of the midgut in the flesh-fly, Sarcophaga bullata (Parker)
    • Nopanitaya W. Misch D.W. Developmental cytology of the midgut in the flesh-fly, Sarcophaga bullata (Parker) Tissue Cell 6 1974 487-502
    • (1974) Tissue Cell , vol.6 , pp. 487-502
    • Nopanitaya, W.1    Misch, D.W.2
  • 73
    • 0035286734 scopus 로고    scopus 로고
    • Molecular dissection of autophagy: Two ubiquitin-like systems
    • Ohsumi Y. Molecular dissection of autophagy: two ubiquitin-like systems Nat. Rev. Mol. Cell Biol. 2 2001 211-216
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 211-216
    • Ohsumi, Y.1
  • 74
    • 0028132203 scopus 로고
    • Caenorrhabditis elegans unc-51 required for axonal elongation encodes a novel serine/threonine kinase
    • Ogura K. Wicky C. Magnenat L. Tobler H. Mori I. Muller F. Ohshima Y. Caenorrhabditis elegans unc-51 required for axonal elongation encodes a novel serine/threonine kinase Genes Dev. 8 1994 2389-2400
    • (1994) Genes Dev. , vol.8 , pp. 2389-2400
    • Ogura, K.1    Wicky, C.2    Magnenat, L.3    Tobler, H.4    Mori, I.5    Muller, F.6    Ohshima, Y.7
  • 75
    • 0037705403 scopus 로고    scopus 로고
    • Macroautophagy is required for multicellular development of the social amoeba Dictyostelium discoideum
    • Otto G.P. Wu M.Y. Kazgan N. Anderson O.R. Kessin R.H. Macroautophagy is required for multicellular development of the social amoeba Dictyostelium discoideum J. Biol. Chem. 278 2003 17636-17645
    • (2003) J. Biol. Chem. , vol.278 , pp. 17636-17645
    • Otto, G.P.1    Wu, M.Y.2    Kazgan, N.3    Anderson, O.R.4    Kessin, R.H.5
  • 76
    • 1842577042 scopus 로고    scopus 로고
    • Dictyostelium macroautophagy mutants vary in the severity of their developmental defects
    • in press. Published online January 21, 2004
    • Otto G.P. Wu M.Y. Kazgan N. Anderson O.R. and Kessin R.H. (2004). Dictyostelium macroautophagy mutants vary in the severity of their developmental defects. J. Biol. Chem., in press. Published online January 21, 2004.
    • (2004) J. Biol. Chem.
    • Otto, G.P.1    Wu, M.Y.2    Kazgan, N.3    Anderson, O.R.4    Kessin, R.H.5
  • 77
    • 0033978633 scopus 로고    scopus 로고
    • Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells
    • Petiot A. Ogier-Denis E. Blommaart E.F. Meijer A.J. Codogno P. Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells J. Biol. Chem. 275 2000 992-998
    • (2000) J. Biol. Chem. , vol.275 , pp. 992-998
    • Petiot, A.1    Ogier-Denis, E.2    Blommaart, E.F.3    Meijer, A.J.4    Codogno, P.5
  • 82
    • 0346503885 scopus 로고    scopus 로고
    • The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure
    • Reggiori F. Tucker K.A. Stromhaug P.E. Klionsky D.J. The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure Dev. Cell 6 2004 79-90
    • (2004) Dev. Cell , vol.6 , pp. 79-90
    • Reggiori, F.1    Tucker, K.A.2    Stromhaug, P.E.3    Klionsky, D.J.4
  • 83
    • 0001104583 scopus 로고    scopus 로고
    • Genetic and environmental regulation of dauer development
    • D. L. Riddle, T. Blumenthal, B. J. Meyer, and J. R. Priess (Eds.), Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
    • Riddle D.L. Genetic and environmental regulation of dauer development In Riddle D.L. Blumenthal T. Meyer B.J. and Priess J.R. (Eds.), C. elegans II 1997 739-768 Cold Spring Harbor Laboratory Press Cold Spring Harbor, NY
    • (1997) C. Elegans II , pp. 739-768
    • Riddle, D.L.1
  • 84
    • 0018650071 scopus 로고
    • Developmental changes in Malpighian tubule cell structure
    • Ryerse J.S. Developmental changes in Malpighian tubule cell structure Tissue Cell 11 1979 533-551
    • (1979) Tissue Cell , vol.11 , pp. 533-551
    • Ryerse, J.S.1
  • 85
    • 0011788471 scopus 로고
    • Ultrastructural changes in the fat body cells of Mamestra brassicae (Noctuidae, Lepidoptera) during metamorphosis
    • Sass M. Kovacs J. Ultrastructural changes in the fat body cells of Mamestra brassicae (Noctuidae, Lepidoptera) during metamorphosis Ann. Univ. Sci. Budap. Rolando Eotvos Sect. Biol. 16 1974 189-205
    • (1974) Ann. Univ. Sci. Budap. Rolando Eotvos Sect. Biol. , vol.16 , pp. 189-205
    • Sass, M.1    Kovacs, J.2
  • 86
    • 0013851178 scopus 로고
    • Lysosomal and free acid phosphatase in salivary glands of chironomus tentans
    • Schin K.S. Clever U. Lysosomal and free acid phosphatase in salivary glands of chironomus tentans Science 150 1965 1053-1055
    • (1965) Science , vol.150 , pp. 1053-1055
    • Schin, K.S.1    Clever, U.2
  • 88
    • 0034644525 scopus 로고    scopus 로고
    • TOR, a central controller of cell growth
    • Schmelzle T. Hall M.N. TOR, a central controller of cell growth Cell 103 2000 253-262
    • (2000) Cell , vol.103 , pp. 253-262
    • Schmelzle, T.1    Hall, M.N.2
  • 89
    • 0015880897 scopus 로고
    • The morphology of various types of cell death in prenatal tissues
    • Schweichel J.-U. Merker H.-J. The morphology of various types of cell death in prenatal tissues Teratology 7 1973 253-266
    • (1973) Teratology , vol.7 , pp. 253-266
    • Schweichel, J.-U.1    Merker, H.-J.2
  • 90
    • 0030897485 scopus 로고    scopus 로고
    • Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products
    • Seaman M.N. Marcusson E.G. Cereghino J.L. Emr S.D. Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products J. Cell Biol. 137 1997 79-92
    • (1997) J. Cell Biol. , vol.137 , pp. 79-92
    • Seaman, M.N.1    Marcusson, E.G.2    Cereghino, J.L.3    Emr, S.D.4
  • 91
    • 0025202901 scopus 로고
    • Social and developmental biology of myxobacteria
    • Shimkets L.J. Social and developmental biology of myxobacteria Microbiol. Rev. 54 1990 473-501
    • (1990) Microbiol. Rev. , vol.54 , pp. 473-501
    • Shimkets, L.J.1
  • 92
    • 0033214582 scopus 로고    scopus 로고
    • Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast
    • Shintani T. Mizushima N. Ogawa Y. Matsuura A. Noda T. Ohsumi Y. Apg10p, a novel protein-conjugating enzyme essential for autophagy in yeast EMBO J. 18 1999 5234-5241
    • (1999) EMBO J. , vol.18 , pp. 5234-5241
    • Shintani, T.1    Mizushima, N.2    Ogawa, Y.3    Matsuura, A.4    Noda, T.5    Ohsumi, Y.6
  • 94
    • 1842419920 scopus 로고    scopus 로고
    • The Berkeley Drosophila genome project gene disruption project: Single P element insertions mutating 25% of vital Drosophila genes
    • Spralding A.C. Stern D. Beaton A. Rhem E.J. Laverty T. Mozden N. Misra S. and Rubin G.M. (1999). The Berkeley Drosophila genome project gene disruption project: single P element insertions mutating 25% of vital Drosophila genes. 153, 155-177.
    • (1999) , vol.153 , pp. 155-177
    • Spralding, A.C.1    Stern, D.2    Beaton, A.3    Rhem, E.J.4    Laverty, T.5    Mozden, N.6    Misra, S.7    Rubin, G.M.8
  • 95
    • 0031008471 scopus 로고    scopus 로고
    • AUT3, a serine/threonine kinase gene, is essential for autophagocytosis in Saccharomyces cerevisiae
    • Straub M. Bredscheider M. Thumm M. AUT3, a serine/threonine kinase gene, is essential for autophagocytosis in Saccharomyces cerevisiae J. Bacteriol. 179 1997 3875-3883
    • (1997) J. Bacteriol. , vol.179 , pp. 3875-3883
    • Straub, M.1    Bredscheider, M.2    Thumm, M.3
  • 96
    • 0348052521 scopus 로고    scopus 로고
    • Cytoplasm to vacuole targeting
    • D. J. Klionsky (Ed.), Georgetown, TX: Landes Bioscience
    • Stromhaug P.E. Klionsky D.J. Cytoplasm to vacuole targeting In Klionsky D.J. (Ed.), Autophagy 2004 84-106 Landes Bioscience Georgetown, TX
    • (2004) Autophagy , pp. 84-106
    • Stromhaug, P.E.1    Klionsky, D.J.2
  • 97
    • 0017618537 scopus 로고
    • Post-embryonic cell lineages of the nematode Caenorhabditis elegans
    • Sulston J.E. Horvitz H.R. Post-embryonic cell lineages of the nematode Caenorhabditis elegans Dev. Biol. 56 1977 110-156
    • (1977) Dev. Biol. , vol.56 , pp. 110-156
    • Sulston, J.E.1    Horvitz, H.R.2
  • 98
    • 0035503594 scopus 로고    scopus 로고
    • The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation
    • Suzuki K. Kirisako T. Kamada Y. Mizushima N. Noda T. Ohsumi Y. The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation EMBO J. 20 2001 5971-5981
    • (2001) EMBO J. , vol.20 , pp. 5971-5981
    • Suzuki, K.1    Kirisako, T.2    Kamada, Y.3    Mizushima, N.4    Noda, T.5    Ohsumi, Y.6
  • 100
    • 0035910423 scopus 로고    scopus 로고
    • The human homolog of Saccharomyces cerevisiae Apg7p is a protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3
    • Tanida I. Tanida-Miyake E. Ueno T. Kominami E. The human homolog of Saccharomyces cerevisiae Apg7p is a protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3 J. Biol. Chem. 276 2001 1701-1706
    • (2001) J. Biol. Chem. , vol.276 , pp. 1701-1706
    • Tanida, I.1    Tanida-Miyake, E.2    Ueno, T.3    Kominami, E.4
  • 102
    • 0037134443 scopus 로고    scopus 로고
    • Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p
    • Tanida I. Tanida-Miyake E. Komatsu M. Ueno T. Kominami E. Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p J. Biol. Chem. 277 2002 13739-13744
    • (2002) J. Biol. Chem. , vol.277 , pp. 13739-13744
    • Tanida, I.1    Tanida-Miyake, E.2    Komatsu, M.3    Ueno, T.4    Kominami, E.5
  • 104
    • 0035910577 scopus 로고    scopus 로고
    • Degradation of lipid vesicles in the yeast vacuole requires function of Cvt17, a putative lipase
    • Teter S.A. Eggerton K.P. Scott S.V. Kim J. Fischer A.M. Klionsky D.J. Degradation of lipid vesicles in the yeast vacuole requires function of Cvt17, a putative lipase J. Biol. Chem. 276 2001 2083-2087
    • (2001) J. Biol. Chem. , vol.276 , pp. 2083-2087
    • Teter, S.A.1    Eggerton, K.P.2    Scott, S.V.3    Kim, J.4    Fischer, A.M.5    Klionsky, D.J.6
  • 105
    • 0035207246 scopus 로고    scopus 로고
    • The loss of Drosophila APG4/AUT2 function modifies the phenotypes of cut and Notch signaling pathway mutants
    • Thumm M. Kadowaki T. The loss of Drosophila APG4/AUT2 function modifies the phenotypes of cut and Notch signaling pathway mutants Mol. Genet. Genomics 266 2001 657-663
    • (2001) Mol. Genet. Genomics , vol.266 , pp. 657-663
    • Thumm, M.1    Kadowaki, T.2
  • 106
    • 0034865119 scopus 로고    scopus 로고
    • Steroid-triggered death by autophagy
    • Thummel C.S. Steroid-triggered death by autophagy Bioessays 23 2001 677-682
    • (2001) Bioessays , vol.23 , pp. 677-682
    • Thummel, C.S.1
  • 107
    • 0027424777 scopus 로고
    • Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
    • Tsukada M. Ohsumi Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae FEBS Lett. 333 1993 169-174
    • (1993) FEBS Lett. , vol.333 , pp. 169-174
    • Tsukada, M.1    Ohsumi, Y.2
  • 109
    • 0038309329 scopus 로고    scopus 로고
    • The molecular mechanism of autophagy
    • Wang C.W. Klionsky D.J. The molecular mechanism of autophagy Mol. Med. 9 2003 65-76
    • (2003) Mol. Med. , vol.9 , pp. 65-76
    • Wang, C.W.1    Klionsky, D.J.2
  • 110
    • 0032895859 scopus 로고    scopus 로고
    • Glucose-induced autophagy of peroxisomes in Pichia pastoris requires a unique E1-like protein
    • Yuan W. Stromhaug P.E. Dunn W.A. Jr. Glucose-induced autophagy of peroxisomes in Pichia pastoris requires a unique E1-like protein Mol. Biol. Cell 10 1999 1353-1366
    • (1999) Mol. Biol. Cell , vol.10 , pp. 1353-1366
    • Yuan, W.1    Stromhaug, P.E.2    Dunn Jr., W.A.3
  • 111
    • 0141884305 scopus 로고    scopus 로고
    • Diversity in the mechanisms of neuronal cell death
    • Yuan J. Lipinski M. Degterev A. Diversity in the mechanisms of neuronal cell death Neuron 40 2003 401-413
    • (2003) Neuron , vol.40 , pp. 401-413
    • Yuan, J.1    Lipinski, M.2    Degterev, A.3
  • 112
    • 0345166111 scopus 로고    scopus 로고
    • Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor
    • Yue Z. Jin S. Yang C. Levine A.J. Heintz N. Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor Proc. Natl. Acad. Sci. USA 100 2003 15077-15082
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 15077-15082
    • Yue, Z.1    Jin, S.2    Yang, C.3    Levine, A.J.4    Heintz, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.