Microarray analysis of the astrocyte transcriptome in the aging brain: Relationship to Alzheimer's pathology and APOE genotype

Neurobiology of Aging

Volumn 32, Issue 10, 2011, Pages 1795-1807

  Simpson, Julie E ^a   Ince, Paul G ^a   Shaw, Pamela J ^a   Heath, Paul R ^a   Raman, Rohini ^a   Garwood, Claire J ^a   Gelsthorpe, Catherine ^a   Baxter, Lynne ^a   Forster, Gillian ^a   Matthews, Fiona E ^b   Brayne, Carol ^b   Wharton, Stephen B ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Alzheimer's disease; APOE; Astrocyte transcriptome; Astrocytes; Brain aging; Microarray analysis

Indexed keywords

ACTIN; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; UBIQUITIN;

AGED; AGING; ALZHEIMER DISEASE; APOE GENE; APOPTOSIS; ARTICLE; ASTROCYTE; CELL PROLIFERATION; CYTOSKELETON; DISEASE CLASSIFICATION; DISEASE SEVERITY; FEMALE; GENE; GENE EXPRESSION PROFILING; GENE FUNCTION; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MICROARRAY ANALYSIS; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; TRANSCRIPTOMICS;

ACTINS; AGED; AGED, 80 AND OVER; AGING; APOLIPOPROTEINS E; ASTROCYTES; FEMALE; GENE EXPRESSION REGULATION; GENOTYPE; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; MALE; MICROARRAY ANALYSIS; MICRODISSECTION; POSTMORTEM CHANGES; REPRODUCIBILITY OF RESULTS; SIGNAL TRANSDUCTION; TEMPORAL LOBE; TRANSCRIPTOME;

EID: 80051576621     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2011.04.013     Document Type: Article

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