-
1
-
-
55749084738
-
A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis
-
Ahn BH, Kim HS, Song S, Lee IH, Liu J, Vassilopoulos A, Deng CX, Finkel T. 2008. A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis. Proc Natl Acad Sci 105: 14447-14452.
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 14447-14452
-
-
Ahn, B.H.1
Kim, H.S.2
Song, S.3
Lee, I.H.4
Liu, J.5
Vassilopoulos, A.6
Deng, C.X.7
Finkel, T.8
-
2
-
-
0036923691
-
Regulation of subtelomeric silencing during stress response
-
DOI 10.1016/S1097-2765(02)00695-0
-
Ai W, Bertram PG, Tsang CK, Chan TF, Zheng XF. 2002. Regulation of subtelomeric silencing during stress response. Mol Cell 10: 1295-1305. (Pubitemid 36050872)
-
(2002)
Molecular Cell
, vol.10
, Issue.6
, pp. 1295-1305
-
-
Ai, W.1
Bertram, P.G.2
Tsang, C.K.3
Chan, T.-F.4
Zheng, X.F.S.5
-
3
-
-
36849002444
-
SIRT3 is pro-apoptotic and participates in distinct basal apoptotic pathways
-
Allison SJ, Milner J. 2007. SIRT3 is pro-apoptotic and participates in distinct basal apoptotic pathways. Cell Cycle 6: 2669-2677. (Pubitemid 350224051)
-
(2007)
Cell Cycle
, vol.6
, Issue.21
, pp. 2669-2677
-
-
Allison, S.J.1
Milner, J.2
-
4
-
-
36348975290
-
SIRT1 is involved in glucocorticoid-mediated control of uncoupling protein-3 gene transcription
-
DOI 10.1074/jbc.M707114200
-
Amat R, Solanes G, Giralt M, Villarroya F. 2007. SIRT1 is involved in glucocorticoid-mediated control of uncoupling protein-3 gene transcription. J Biol Chem 282: 34066-34076. (Pubitemid 350159429)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.47
, pp. 34066-34076
-
-
Amat, R.1
Solanes, G.2
Giralt, M.3
Villarroya, F.4
-
6
-
-
0038329323
-
Nicatinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae
-
DOI 10.1038/nature01578
-
Anderson RM, Bitterman KJ, Wood JG, Medvedik O, Sinclair DA. 2003. Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae. Nature 423: 181-185. (Pubitemid 36569542)
-
(2003)
Nature
, vol.423
, Issue.6936
, pp. 181-185
-
-
Anderson, R.M.1
Bitterman, K.J.2
Wood, J.G.3
Medvedik, O.4
Sinclair, D.A.5
-
7
-
-
4043165678
-
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
-
DOI 10.1126/science.1098014
-
Araki T, Sasaki Y, Milbrandt J. 2004. Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 305: 1010-1013. (Pubitemid 39071777)
-
(2004)
Science
, vol.305
, Issue.5686
, pp. 1010-1013
-
-
Araki, T.1
Sasaki, Y.2
Milbrandt, J.3
-
8
-
-
47749140333
-
SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation
-
DOI 10.1016/j.cell.2008.06.050, PII S0092867408008374
-
Asher G, Gatfield D, Stratmann M, Reinke H, Dibner C, Kreppel F, Mostoslavsky R, Alt FW, Schibler U. 2008. SIRT1 regulates circadian clock gene expression through PER2 deacetylation. Cell 134: 317-328. (Pubitemid 352024391)
-
(2008)
Cell
, vol.134
, Issue.2
, pp. 317-328
-
-
Asher, G.1
Gatfield, D.2
Stratmann, M.3
Reinke, H.4
Dibner, C.5
Kreppel, F.6
Mostoslavsky, R.7
Alt, F.W.8
Schibler, U.9
-
9
-
-
3142548829
-
Human histone deacetylase SIRT2 interacts with the homeobox transcription factor HOXA10
-
DOI 10.1093/jb/mvh084
-
Bae NS, Swanson MJ, Vassilev A, Howard BH. 2004. Human histone deacetylase SIRT2 interacts with the homeobox transcription factor HOXA10. J Biochem (Tokyo) 135: 695-700. (Pubitemid 38899716)
-
(2004)
Journal of Biochemistry
, vol.135
, Issue.6
, pp. 695-700
-
-
Bael, N.S.1
Swanson, M.J.2
Vassilev, A.3
Howard, B.H.4
-
10
-
-
52749091816
-
SirT1 gain of function increases energy efficiency and prevents diabetes in mice
-
Banks AS, Kon N, Knight C, Matsumoto M, Gutierrez-Juarez R, Rossetti L, Gu W, Accili D. 2008. SirT1 gain of function increases energy efficiency and prevents diabetes in mice. Cell Metab 8: 333-341.
-
(2008)
Cell Metab
, vol.8
, pp. 333-341
-
-
Banks, A.S.1
Kon, N.2
Knight, C.3
Matsumoto, M.4
Gutierrez-Juarez, R.5
Rossetti, L.6
Gu, W.7
Accili, D.8
-
11
-
-
55849132493
-
Insulin and aging
-
Bartke A. 2008. Insulin and aging. Cell Cycle 7: 3338-3343.
-
(2008)
Cell Cycle
, vol.7
, pp. 3338-3343
-
-
Bartke, A.1
-
12
-
-
3242886115
-
DNA damage responses to oxidative stress
-
DOI 10.1016/j.dnarep.2004.03.002, PII S1568786404000618
-
Barzilai A, Yamamoto K. 2004. DNA damage responses to oxidative stress. DNA Repair (Amst) 3: 1109-1115. (Pubitemid 38997954)
-
(2004)
DNA Repair
, vol.3
, Issue.8-9
, pp. 1109-1115
-
-
Barzilai, A.1
Yamamoto, K.-I.2
-
13
-
-
0037023326
-
The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylation
-
Bell SD, Botting CH, Wardleworth BN, Jackson SP, White MF. 2002. The interaction of Alba, a conserved archaeal chromatin protein, with Sir2 and its regulation by acetylation. Science 296: 148-151.
-
(2002)
Science
, vol.296
, pp. 148-151
-
-
Bell, S.D.1
Botting, C.H.2
Wardleworth, B.N.3
Jackson, S.P.4
White, M.F.5
-
14
-
-
34047095297
-
The two TORCs and Akt
-
Bhaskar PT, Hay N. 2007. The two TORCs and Akt. Dev Cell 12: 487-502.
-
(2007)
Dev Cell
, vol.12
, pp. 487-502
-
-
Bhaskar, P.T.1
Hay, N.2
-
15
-
-
55049117907
-
The SIRT2 deacetylase regulates autoacetylation of p300
-
Black JC, Mosley A, Kitada T, Washburn M, Carey M. 2008. The SIRT2 deacetylase regulates autoacetylation of p300. Mol Cell 32: 449-455.
-
(2008)
Mol Cell
, vol.32
, pp. 449-455
-
-
Black, J.C.1
Mosley, A.2
Kitada, T.3
Washburn, M.4
Carey, M.5
-
16
-
-
45549098657
-
SirT1 regulates energy metabolism and response to caloric restriction in mice
-
DOI 10.1371/journal.pone.0001759
-
Boily G, Seifert EL, Bevilacqua L, He XH, Sabourin G, Estey C, Moffat C, Crawford S, Saliba S, Jardine K, et al. 2008. SirT1 regulates energy metabolism and response to caloric restriction in mice. PLoS One 3: e1759. doi: 10.1371/journal.pone.0001759. (Pubitemid 351903300)
-
(2008)
PLoS ONE
, vol.3
, Issue.3
-
-
Boily, G.1
Seifert, E.L.2
Bevilacqua, L.3
He, X.H.4
Sabourin, G.5
Estey, C.6
Moffat, C.7
Crawford, S.8
Saliba, S.9
Jardine, K.10
Xuan, J.11
Evans, M.12
Harper, M.-E.13
McBurney, M.W.14
-
18
-
-
15444377466
-
SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1
-
DOI 10.1074/jbc.M408748200
-
Bouras T, Fu M, Sauve AA, Wang F, Quong AA, Perkins ND, Hay RT, Gu W, Pestell RG. 2005. SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1. J Biol Chem 280: 10264-10276. (Pubitemid 40395882)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.11
, pp. 10264-10276
-
-
Bouras, T.1
Fu, M.2
Sauve, A.A.3
Wang, F.4
Quong, A.A.5
Perkins, N.D.6
Hay, R.T.7
Gu, W.8
Pestell, R.G.9
-
19
-
-
0027509346
-
A region in the C-terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation tumorigenesis and metastasis
-
Boyd JM, Subramanian T, Schaeper U, La Regina M, Bayley S, Chinnadurai G. 1993. A region in the C-terminus of adenovirus 2/5 E1a protein is required for association with a cellular phosphoprotein and important for the negative modulation of T24-ras mediated transformation, tumorigenesis and metastasis. EMBO J 12: 469-478. (Pubitemid 23073693)
-
(1993)
EMBO Journal
, vol.12
, Issue.2
, pp. 469-478
-
-
Boyd, J.M.1
Subramanian, T.2
Schaeper, U.3
La Regina, M.4
Bayley, S.5
Chinnadurai, G.6
-
20
-
-
12144290563
-
Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase
-
DOI 10.1126/science.1094637
-
Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y, Tran H, Ross SE, Mostoslavsky R, Cohen HY, et al. 2004. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303: 2011-2015. (Pubitemid 38393275)
-
(2004)
Science
, vol.303
, Issue.5666
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsy, R.9
Cohen, H.Y.10
Hu, L.S.11
Cheng, H.-L.12
Jedrychowski, M.P.13
Gygi, S.P.14
Sinclair, D.A.15
Alt, F.W.16
Greenberg, M.E.17
-
21
-
-
0037353433
-
Caloric restriction promotes genomic stability by induction of base excision repair and reversal of its age-related decline
-
DOI 10.1016/S1568-7864(02)00219-7, PII S1568786402002197
-
Cabelof DC, Yanamadala S, Raffoul JJ, Guo Z, Soofi A, Heydari AR. 2003. Caloric restriction promotes genomic stability by induction of base excision repair and reversal of its age-related decline. DNA Repair (Amst) 2: 295-307. (Pubitemid 36126398)
-
(2003)
DNA Repair
, vol.2
, Issue.3
, pp. 295-307
-
-
Cabelof, D.C.1
Yanamadala, S.2
Raffoul, J.J.3
Guo, Z.4
Soofi, A.5
Heydari, A.R.6
-
22
-
-
28844469898
-
Medicine: Increase in activity during calorie restriction requires Sirt1
-
DOI 10.1126/science.1118357
-
Chen D, Steele AD, Lindquist S, Guarente L. 2005. Increase in activity during calorie restriction requires Sirt1. Science 310: 1641. doi: 10.1126/science.1118357. (Pubitemid 41780779)
-
(2005)
Science
, vol.310
, Issue.5754
, pp. 1641
-
-
Chen, D.1
Steele, A.D.2
Lindquist, S.3
Guarente, L.4
-
23
-
-
27544434763
-
Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses
-
DOI 10.1016/j.cell.2005.08.011, PII S0092867405008159
-
Chen WY, Wang DH, Yen RC, Luo J, Gu W, Baylin SB. 2005. Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses. Cell 123: 437-448. (Pubitemid 41546674)
-
(2005)
Cell
, vol.123
, Issue.3
, pp. 437-448
-
-
Wen, Y.C.1
Wang, D.H.2
Raywhay, C.Y.3
Luo, J.4
Gu, W.5
Baylin, S.B.6
-
24
-
-
33745855834
-
Histone H2A.z is essential for cardiac myocyte hypertrophy but opposed by silent information regulator 2a
-
DOI 10.1074/jbc.M601443200
-
Chen IY, Lypowy J, Pain J, Sayed D, Grinberg S, Alcendor RR, Sadoshima J, Abdellatif M. 2006. Histone H2A.z is essential for cardiac myocyte hypertrophy but opposed by silent information regulator 2a. J Biol Chem 281: 19369-19377. (Pubitemid 44035442)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.28
, pp. 19369-19377
-
-
Chen, I.-Y.1
Lypowy, J.2
Pain, J.3
Sayed, D.4
Grinberg, S.5
Alcendor, R.R.6
Sadoshima, J.7
Abdellatif, M.8
-
25
-
-
46249100836
-
Tissue-specific regulation of SIRT1 by calorie restriction
-
DOI 10.1101/gad.1650608
-
Chen D, Bruno J, Easlon E, Lin SJ, Cheng HL, Alt FW, Guarente L. 2008a. Tissue-specific regulation of SIRT1 by calorie restriction. Genes & Dev 22: 1753-1757. (Pubitemid 351915500)
-
(2008)
Genes and Development
, vol.22
, Issue.13
, pp. 1753-1757
-
-
Chen, D.1
Bruno, J.2
Easlon, E.3
Lin, S.-J.4
Cheng, H.-L.5
Alt, F.W.6
Guarente, L.7
-
26
-
-
56349151227
-
The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration
-
Chen D, Steele AD, Hutter G, Bruno J, Govindarajan A, Easlon E, Lin SJ, Aguzzi A, Lindquist S, Guarente L. 2008b. The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration. Exp Gerontol 43: 1086-1093.
-
(2008)
Exp Gerontol
, vol.43
, pp. 1086-1093
-
-
Chen, D.1
Steele, A.D.2
Hutter, G.3
Bruno, J.4
Govindarajan, A.5
Easlon, E.6
Lin, S.J.7
Aguzzi, A.8
Lindquist, S.9
Guarente, L.10
-
27
-
-
0141814680
-
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
-
Cheng HL, Mostoslavsky R, Saito S, Manis JP, Gu Y, Patel P, Bronson R, Appella E, Alt FW, Chua KF. 2003. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci 100: 10794-10799.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 10794-10799
-
-
Cheng, H.L.1
Mostoslavsky, R.2
Saito, S.3
Manis, J.P.4
Gu, Y.5
Patel, P.6
Bronson, R.7
Appella, E.8
Alt, F.W.9
Chua, K.F.10
-
28
-
-
34447632818
-
Transcriptional regulation by C-terminal binding proteins
-
DOI 10.1016/j.biocel.2007.01.025, PII S1357272507000453
-
Chinnadurai G. 2007. Transcriptional regulation by C-terminal binding proteins. Int J Biochem Cell Biol 39: 1593-1607. (Pubitemid 47088308)
-
(2007)
International Journal of Biochemistry and Cell Biology
, vol.39
, Issue.9
, pp. 1593-1607
-
-
Chinnadurai, G.1
-
29
-
-
13844318224
-
Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases
-
DOI 10.1146/annurev.pharmtox.45.120403.095902
-
Chuang DM, Hough C, Senatorov VV. 2005. Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases. Annu Rev Pharmacol Toxicol 45: 269-290. (Pubitemid 40261806)
-
(2005)
Annual Review of Pharmacology and Toxicology
, vol.45
, pp. 269-290
-
-
Chuang, D.-M.1
Hough, C.2
Senatorov, V.V.3
-
30
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
DOI 10.1126/science.1099196
-
Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, Kessler B, Howitz KT, Gorospe M, de Cabo R, Sinclair DA. 2004. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 305: 390-392. (Pubitemid 38938153)
-
(2004)
Science
, vol.305
, Issue.5682
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
Howitz, K.T.7
Gorospe, M.8
De Cabo, R.9
Sinclair, D.A.10
-
31
-
-
67149099680
-
Histone H4 lysine 16 acetylation regulates cellular lifespan
-
Dang W, Steffen KK, Perry R, Dorsey JA, Johnson FB, Shilatifard A, Kaeberlein M, Kennedy BK, Berger SL. 2009. Histone H4 lysine 16 acetylation regulates cellular lifespan. Nature 459: 802-807.
-
(2009)
Nature
, vol.459
, pp. 802-807
-
-
Dang, W.1
Steffen, K.K.2
Perry, R.3
Dorsey, J.A.4
Johnson, F.B.5
Shilatifard, A.6
Kaeberlein, M.7
Kennedy, B.K.8
Berger, S.L.9
-
32
-
-
33947521255
-
Calorie restriction and the nutrient sensing signaling pathways
-
DOI 10.1007/s00018-007-6381-y
-
Dilova I, Easlon E, Lin SJ. 2007. Calorie restriction and the nutrient sensing signaling pathways. Cell Mol Life Sci 64: 752-767. (Pubitemid 46474982)
-
(2007)
Cellular and Molecular Life Sciences
, vol.64
, Issue.6
, pp. 752-767
-
-
Dilova, I.1
Easlon, E.2
Lin, S.-J.3
-
33
-
-
0037405043
-
Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle
-
Dryden SC, Nahhas FA, Nowak JE, Goustin AS, Tainsky MA. 2003. Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle. Mol Cell Biol 23: 3173-3185.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 3173-3185
-
-
Dryden, S.C.1
Nahhas, F.A.2
Nowak, J.E.3
Goustin, A.S.4
Tainsky, M.A.5
-
34
-
-
34249681648
-
Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells
-
DOI 10.1093/nar/gkm118
-
Espada J, Ballestar E, Santoro R, Fraga MF, Villar-Garea A, Nemeth A, Lopez-Serra L, Ropero S, Aranda A, Orozco H, et al. 2007. Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells. Nucleic Acids Res 35: 2191-2198. (Pubitemid 47073707)
-
(2007)
Nucleic Acids Research
, vol.35
, Issue.7
, pp. 2191-2198
-
-
Espada, J.1
Ballestar, E.2
Santoro, R.3
Fraga, M.F.4
Villar-Garea, A.5
Nemeth, A.6
Lopez-Serra, L.7
Ropero, S.8
Aranda, A.9
Orozco, H.10
Moreno, V.11
Juarranz, A.12
Stockert, J.C.13
Langst, G.14
Grummt, I.15
Bickmore, W.16
Esteller, M.17
-
35
-
-
0035853552
-
Regulation of longevity and stress resistance by Sch9 in yeast
-
DOI 10.1126/science.1059497
-
Fabrizio P, Pozza F, Pletcher SD, Gendron CM, Longo VD. 2001. Regulation of longevity and stress resistance by Sch9 in yeast. Science 292: 288-290. (Pubitemid 32295387)
-
(2001)
Science
, vol.292
, Issue.5515
, pp. 288-290
-
-
Fabrizio, P.1
Pozza, F.2
Pletcher, S.D.3
Gendron, C.M.4
Longo, V.D.5
-
36
-
-
34249727164
-
Transcriptional coregulators in the control of energy homeostasis
-
DOI 10.1016/j.tcb.2007.04.001, PII S0962892407000840
-
Feige JN, Auwerx J. 2007. Transcriptional coregulators in the control of energy homeostasis. Trends Cell Biol 17: 292-301. (Pubitemid 46829846)
-
(2007)
Trends in Cell Biology
, vol.17
, Issue.6
, pp. 292-301
-
-
Feige, J.N.1
Auwerx, J.2
-
37
-
-
54849425547
-
Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation
-
Feige JN, Lagouge M, Canto C, Strehle A, Houten SM, Milne JC, Lambert PD, Mataki C, Elliott PJ, Auwerx J. 2008. Specific SIRT1 activation mimics low energy levels and protects against diet-induced metabolic disorders by enhancing fat oxidation. Cell Metab 8: 347-358.
-
(2008)
Cell Metab
, vol.8
, pp. 347-358
-
-
Feige, J.N.1
Lagouge, M.2
Canto, C.3
Strehle, A.4
Houten, S.M.5
Milne, J.C.6
Lambert, P.D.7
Mataki, C.8
Elliott, P.J.9
Auwerx, J.10
-
38
-
-
0041923828
-
+ and NADH allows the transcriptional corepressor carboxyl-terminal binding protein to serve as a metabolic sensor
-
+ and NADH allows the transcriptional corepressor carboxyl-terminal binding protein to serve as a metabolic sensor. Proc Natl Acad Sci 100: 9202-9207.
-
(2003)
Proc Natl Acad Sci
, vol.100
, pp. 9202-9207
-
-
Fjeld, C.C.1
Birdsong, W.T.2
Goodman, R.H.3
-
39
-
-
0023875830
-
Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene
-
Fletcher C, Heintz N, Roeder RG. 1987. Purification and characterization of OTF-1, a transcription factor regulating cell cycle expression of a human histone H2b gene. Cell 51: 773-781. (Pubitemid 18142924)
-
(1988)
Cell
, vol.53
, Issue.5
, pp. 773-781
-
-
Fletcher, C.1
Heintz, N.2
Roeder, R.G.3
-
40
-
-
33744466971
-
Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription
-
Ford E, Voit R, Liszt G, Magin C, Grummt I, Guarente L. 2006. Mammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcription. Genes & Dev 20: 1075-1080.
-
(2006)
Genes & Dev
, vol.20
, pp. 1075-1080
-
-
Ford, E.1
Voit, R.2
Liszt, G.3
Magin, C.4
Grummt, I.5
Guarente, L.6
-
41
-
-
41549132495
-
LSD1: Oxidative chemistry for multifaceted functions in chromatin regulation
-
Forneris F, Binda C, Battaglioli E, Mattevi A. 2008. LSD1: Oxidative chemistry for multifaceted functions in chromatin regulation. Trends Biochem Sci 33: 181-189.
-
(2008)
Trends Biochem Sci
, vol.33
, pp. 181-189
-
-
Forneris, F.1
Binda, C.2
Battaglioli, E.3
Mattevi, A.4
-
42
-
-
33750969375
-
Tissue specific and non-specific changes in gene expression by aging and by early stage CR
-
DOI 10.1016/j.mad.2006.09.006, PII S0047637406002181
-
Fu C, Hickey M, Morrison M, McCarter R, Han ES. 2006. Tissue specific and non-specific changes in gene expression by aging and by early stage CR. Mech Ageing Dev 127: 905-916. (Pubitemid 44751895)
-
(2006)
Mechanisms of Ageing and Development
, vol.127
, Issue.12
, pp. 905-916
-
-
Fu, C.1
Hickey, M.2
Morrison, M.3
McCarter, R.4
Han, E.-S.5
-
43
-
-
0038412822
-
The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase
-
DOI 10.1093/nar/gkg332
-
Fuks F, Hurd PJ, Deplus R, Kouzarides T. 2003. The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase. Nucleic Acids Res 31: 2305 2312. (Pubitemid 37442098)
-
(2003)
Nucleic Acids Research
, vol.31
, Issue.9
, pp. 2305-2312
-
-
Fuks, F.1
Hurd, P.J.2
Deplus, R.3
Kouzarides, T.4
-
44
-
-
0043244921
-
Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state
-
DOI 10.1016/S1097-2765(03)00226-0
-
Fulco M, Schiltz RL, Iezzi S, King MT, Zhao P, Kashiwaya Y, Hoffman E, Veech RL, Sartorelli V. 2003. Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state. Mol Cell 12: 51-62. (Pubitemid 36945036)
-
(2003)
Molecular Cell
, vol.12
, Issue.1
, pp. 51-62
-
-
Fulco, M.1
Schiltz, R.L.2
Iezzi, S.3
King, M.T.4
Zhao, P.5
Kashiwaya, Y.6
Hoffman, E.7
Veech, R.L.8
Sartorelli, V.9
-
45
-
-
43049121395
-
Glucose Restriction Inhibits Skeletal Myoblast Differentiation by Activating SIRT1 through AMPK-Mediated Regulation of Nampt
-
DOI 10.1016/j.devcel.2008.02.004, PII S1534580708000749
-
Fulco M, Cen Y, Zhao P, Hoffman EP, McBurney MW, Sauve AA, Sartorelli V. 2008. Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Dev Cell 14: 661-673. (Pubitemid 351622608)
-
(2008)
Developmental Cell
, vol.14
, Issue.5
, pp. 661-673
-
-
Fulco, M.1
Cen, Y.2
Zhao, P.3
Hoffman, E.P.4
McBurney, M.W.5
Sauve, A.A.6
Sartorelli, V.7
-
46
-
-
6944253702
-
SIR2 is required for polycomb silencing and is associated with an E(Z) histone methyltransferase complex
-
DOI 10.1016/j.cub.2004.09.060, PII S0960982204007742
-
Furuyama T, Banerjee R, Breen TR, Harte PJ. 2004. SIR2 is required for polycomb silencing and is associated with an E(Z) histone methyltransferase complex. Curr Biol 14: 1812-1821. (Pubitemid 39408770)
-
(2004)
Current Biology
, vol.14
, Issue.20
, pp. 1812-1821
-
-
Furuyama, T.1
Banerjee, R.2
Breen, T.R.3
Harte, P.J.4
-
47
-
-
64849107827
-
Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis
-
Grob A, Roussel P, Wright JE, McStay B, Hernandez-Verdun D, Sirri V. 2009. Involvement of SIRT7 in resumption of rDNA transcription at the exit from mitosis. J Cell Sci 122: 489-498.
-
(2009)
J Cell Sci
, vol.122
, pp. 489-498
-
-
Grob, A.1
Roussel, P.2
Wright, J.E.3
McStay, B.4
Hernandez-Verdun, D.5
Sirri, V.6
-
48
-
-
0034193776
-
Sir2 links chromatin silencing, metabolism, and aging
-
Guarente L. 2000. Sir2 links chromatin silencing, metabolism, and aging. Genes & Dev 14: 1021-1026. (Pubitemid 30324417)
-
(2000)
Genes and Development
, vol.14
, Issue.9
, pp. 1021-1026
-
-
Guarente, L.1
-
49
-
-
38649132337
-
Mitochondria - A nexus for aging, calorie restriction, and sirtuins?
-
Guarente L. 2008. Mitochondria - A nexus for aging, calorie restriction, and sirtuins? Cell 132: 171-176.
-
(2008)
Cell
, vol.132
, pp. 171-176
-
-
Guarente, L.1
-
50
-
-
13944253348
-
Calorie restriction - The SIR2 connection
-
Guarente L, Picard F. 2005. Calorie restriction - The SIR2 connection. Cell 120: 473-482.
-
(2005)
Cell
, vol.120
, pp. 473-482
-
-
Guarente, L.1
Picard, F.2
-
51
-
-
0000679957
-
Nucleotide excision repair of actively transcribed versus nontranscribed DNA in rat hepatocytes: Effect of age and dietary restriction
-
DOI 10.1006/excr.1998.4269
-
Guo Z, Heydari A, Richardson A. 1998. Nucleotide excision repair of actively transcribed versus nontranscribed DNA in rat hepatocytes: Effect of age and dietary restriction. Exp Cell Res 245: 228-238. (Pubitemid 28551074)
-
(1998)
Experimental Cell Research
, vol.245
, Issue.1
, pp. 228-238
-
-
Guo, Z.M.1
Heydari, A.2
Richardson, A.3
-
52
-
-
37549014206
-
The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis
-
Gupta A, Guerin-Peyrou TG, Sharma GG, Park C, Agarwal M, Ganju RK, Pandita S, Choi K, Sukumar S, Pandita RK, et al. 2008. The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis. Mol Cell Biol 28: 397-409.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 397-409
-
-
Gupta, A.1
Guerin-Peyrou, T.G.2
Sharma, G.G.3
Park, C.4
Agarwal, M.5
Ganju, R.K.6
Pandita, S.7
Choi, K.8
Sukumar, S.9
Pandita, R.K.10
-
53
-
-
1842611977
-
Antioxidants Inhibit Nuclear Export of Telomerase Reverse Transcriptase and Delay Replicative Senescence of Endothelial Cells
-
DOI 10.1161/01.RES.0000121104.05977.F3
-
Haendeler J, Hoffmann J, Diehl JF, Vasa M, Spyridopoulos I, Zeiher AM, Dimmeler S. 2004. Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells. Circ Res 94: 768-775. (Pubitemid 38451738)
-
(2004)
Circulation Research
, vol.94
, Issue.6
, pp. 768-775
-
-
Haendeler, J.1
Hoffmann, J.2
Diehl, J.F.3
Vasa, M.4
Spyridopoulos, I.5
Zeiher, A.M.6
Dimmeler, S.7
-
54
-
-
0032823769
-
Antioxidant defence mechanisms: From the beginning to the end (of the beginning)
-
DOI 10.1080/10715769900300841
-
Halliwell B. 1999. Antioxidant defence mechanisms: From the beginning to the end (of the beginning). Free Radic Res 31: 261-272. (Pubitemid 29452853)
-
(1999)
Free Radical Research
, vol.31
, Issue.4
, pp. 261-272
-
-
Halliwell, B.1
-
55
-
-
33745931074
-
Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases
-
Hallows WC, Lee S, Denu JM. 2006. Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases. Proc Natl Acad Sci 103: 10230-10235.
-
(2006)
Proc Natl Acad Sci
, vol.103
, pp. 10230-10235
-
-
Hallows, W.C.1
Lee, S.2
Denu, J.M.3
-
56
-
-
4043171462
-
Upstream and downstream of mTOR
-
Hay N, Sonenberg N. 2004. Upstream and downstream of mTOR. Genes & Dev 18: 1926-1945.
-
(2004)
Genes & Dev
, vol.18
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
58
-
-
0642375804
-
Chromosomal DNA fragmentation in apoptosis and necrosis induced by oxidative stress
-
DOI 10.1016/S0006-2952(03)00508-2, PII S0006295203005082
-
Higuchi Y. 2003. Chromosomal DNA fragmentation in apoptosis and necrosis induced by oxidative stress. Biochem Pharmacol 66: 1527-1535. (Pubitemid 38373343)
-
(2003)
Biochemical Pharmacology
, vol.66
, Issue.8
, pp. 1527-1535
-
-
Higuchi, Y.1
-
59
-
-
3242659914
-
Effects of age and caloric restriction on brain neuronal cell death/survival
-
DOI 10.1196/annals.1297.018
-
Hiona A, Leeuwenburgh C. 2004. Effects of age and caloric restriction on brain neuronal cell death/survival. Ann N Y Acad Sci 1019: 96-105. (Pubitemid 38951291)
-
(2004)
Annals of the New York Academy of Sciences
, vol.1019
, pp. 96-105
-
-
Hiona, A.1
Leeuwenburgh, C.2
-
60
-
-
0041829415
-
Proteomics-based identification of differentially expressed genes in human gliomas: Down-regulation of SIRT2 gene
-
DOI 10.1016/j.bbrc.2003.08.029
-
Hiratsuka M, Inoue T, Toda T, Kimura N, Shirayoshi Y, Kamitani H, Watanabe T, Ohama E, Tahimic CG, Kurimasa A, et al. 2003. Proteomics-based identification of differentially expressed genes in human gliomas: Down-regulation of SIRT2 gene. Biochem Biophys Res Commun 309: 558-566. (Pubitemid 37083288)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.309
, Issue.3
, pp. 558-566
-
-
Hiratsuka, M.1
Inoue, T.2
Toda, T.3
Kimura, N.4
Shirayoshi, Y.5
Kamitani, H.6
Watanabe, T.7
Ohama, E.8
Tahimic, C.G.T.9
Kurimasa, A.10
Oshimura, M.11
-
61
-
-
58249098507
-
A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress
-
Huang Q, Wu YT, Tan HL, Ong CN, Shen HM. 2009. A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress. Cell Death Differ 16: 264-277.
-
(2009)
Cell Death Differ
, vol.16
, pp. 264-277
-
-
Huang, Q.1
Wu, Y.T.2
Tan, H.L.3
Ong, C.N.4
Shen, H.M.5
-
62
-
-
0013072999
-
Calorie Restriction, Aging, and Cancer Prevention: Mechanisms of Action and Applicability to Humans
-
DOI 10.1146/annurev.med.54.101601.152156
-
Hursting SD, Lavigne JA, Berrigan D, Perkins SN, Barrett JC. 2003. Calorie restriction, aging, and cancer prevention: Mechanisms of action and applicability to humans. Annu Rev Med 54: 131-152. (Pubitemid 37386388)
-
(2003)
Annual Review of Medicine
, vol.54
, pp. 131-152
-
-
Hursting, S.D.1
Lavigne, J.A.2
Berrigan, D.3
Perkins, S.N.4
Barrett, J.C.5
-
63
-
-
0034677535
-
Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase
-
DOI 10.1038/35001622
-
Imai S, Armstrong CM, Kaeberlein M, Guarente L. 2000. Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 403: 795-800. (Pubitemid 30111843)
-
(2000)
Nature
, vol.403
, Issue.6771
, pp. 795-800
-
-
Imai, S.-I.1
Armstrong, C.M.2
Kaeberlein, M.3
Guarente, L.4
-
64
-
-
34248151365
-
The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation
-
Inoue T, Hiratsuka M, Osaki M, Oshimura M. 2007a. The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation. Cell Cycle 6: 1011-1018. (Pubitemid 46708571)
-
(2007)
Cell Cycle
, vol.6
, Issue.9
, pp. 1011-1018
-
-
Inoue, T.1
Hiratsuka, M.2
Osaki, M.3
Oshimura, M.4
-
65
-
-
33847053144
-
SIRT2, a tubulin deacetylase, acts to block the entry to chromosome condensation in response to mitotic stress
-
DOI 10.1038/sj.onc.1209857, PII 1209857
-
Inoue T, Hiratsuka M, Osaki M, Yamada H, Kishimoto I, Yamaguchi S, Nakano S, Katoh M, Ito H, Oshimura M. 2007b. SIRT2, a tubulin deacetylase, acts to block the entry to chromosome condensation in response to mitotic stress. Oncogene 26: 945-957. (Pubitemid 46272207)
-
(2007)
Oncogene
, vol.26
, Issue.7
, pp. 945-957
-
-
Inoue, T.1
Hiratsuka, M.2
Osaki, M.3
Yamada, H.4
Kishimoto, I.5
Yamaguchi, S.6
Nakano, S.7
Katoh, M.8
Ito, H.9
Oshimura, M.10
-
66
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito K, Hirao A, Arai F, Takubo K, Matsuoka S, Miyamoto K, Ohmura M, Naka K, Hosokawa K, Ikeda Y, et al. 2006. Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med 12: 446-451.
-
(2006)
Nat Med
, vol.12
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Takubo, K.4
Matsuoka, S.5
Miyamoto, K.6
Ohmura, M.7
Naka, K.8
Hosokawa, K.9
Ikeda, Y.10
-
67
-
-
39749143163
-
Sirt2 interacts with 14-3-3 β/γ and down-regulates the activity of p53
-
Jin YH, Kim YJ, Kim DW, Baek KH, Kang BY, Yeo CY, Lee KY. 2008. Sirt2 interacts with 14-3-3 β/γ and down-regulates the activity of p53. Biochem Biophys Res Commun 368: 690-695.
-
(2008)
Biochem Biophys Res Commun
, vol.368
, pp. 690-695
-
-
Jin, Y.H.1
Kim, Y.J.2
Kim, D.W.3
Baek, K.H.4
Kang, B.Y.5
Yeo, C.Y.6
Lee, K.Y.7
-
68
-
-
19344374925
-
Sir2-independent life span extension by calorie restriction in yeast
-
DOI 10.1371/journal.pbio.0020296
-
Kaeberlein M, Kirkland KT, Fields S, Kennedy BK. 2004. Sir2-independent life span extension by calorie restriction in yeast. PLoS Biol 2: E296. doi: 10.1371/journal.pbio.0020296. (Pubitemid 39245247)
-
(2004)
PLoS Biology
, vol.2
, Issue.9
-
-
Kaeberlein, M.1
Kirkland, K.T.2
Fields, S.3
Kennedy, B.K.4
-
69
-
-
39649100868
-
Regulation of SIRT6 protein levels by nutrient availability
-
Kanfi Y, Shalman R, Peshti V, Pilosof SN, Gozlan YM, Pearson KJ, Lerrer B, Moazed D, Marine JC, de Cabo R, et al. 2008. Regulation of SIRT6 protein levels by nutrient availability. FEBS Lett 582: 543-548.
-
(2008)
FEBS Lett
, vol.582
, pp. 543-548
-
-
Kanfi, Y.1
Shalman, R.2
Peshti, V.3
Pilosof, S.N.4
Gozlan, Y.M.5
Pearson, K.J.6
Lerrer, B.7
Moazed, D.8
Marine, J.C.9
De Cabo, R.10
-
70
-
-
0037022534
-
Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants
-
DOI 10.1016/S0960-9822(02)00684-X, PII S096098220200684X
-
Karanjawala ZE, Murphy N, Hinton DR, Hsieh CL, Lieber MR. 2002. Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants. Curr Biol 12: 397-402. (Pubitemid 34209287)
-
(2002)
Current Biology
, vol.12
, Issue.5
, pp. 397-402
-
-
Karanjawala, Z.E.1
Murphy, N.2
Hinton, D.R.3
Hsieh, C.-L.4
Lieber, M.R.5
-
71
-
-
58149090925
-
SIRT6 links histone H3 lysine 9 deacetylation to NF-κB-dependent gene expression and organismal life span
-
Kawahara TL, Michishita E, Adler AS, Damian M, Berber E, Lin M, McCord RA, Ongaigui KC, Boxer LD, Chang HY, et al. 2009. SIRT6 links histone H3 lysine 9 deacetylation to NF-κB-dependent gene expression and organismal life span. Cell 136: 62-74.
-
(2009)
Cell
, vol.136
, pp. 62-74
-
-
Kawahara, T.L.1
Michishita, E.2
Adler, A.S.3
Damian, M.4
Berber, E.5
Lin, M.6
McCord, R.A.7
Ongaigui, K.C.8
Boxer, L.D.9
Chang, H.Y.10
-
73
-
-
14744284637
-
Multifaceted roles of glycolytic enzymes
-
Kim JW, Dang CV. 2005. Multifaceted roles of glycolytic enzymes. Trends Biochem Sci 30: 142-150.
-
(2005)
Trends Biochem Sci
, vol.30
, pp. 142-150
-
-
Kim, J.W.1
Dang, C.V.2
-
75
-
-
34447308268
-
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis
-
DOI 10.1038/sj.emboj.7601758, PII 7601758
-
Kim D, Nguyen MD, Dobbin MM, Fischer A, Sananbenesi F, Rodgers JT, Delalle I, Baur JA, Sui G, Armour SM, et al. 2007. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. EMBO J 26: 3169-3179. (Pubitemid 47057498)
-
(2007)
EMBO Journal
, vol.26
, Issue.13
, pp. 3169-3179
-
-
Kim, D.1
Nguyen, M.D.2
Dobbin, M.M.3
Fischer, A.4
Sananbenesi, F.5
Rodgers, J.T.6
Delalle, I.7
Baur, J.A.8
Sui, G.9
Armour, S.M.10
Puigserver, P.11
Sinclair, D.A.12
Tsai, L.-H.13
-
76
-
-
33744475759
-
Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage
-
Kolthur-Seetharam U, Dantzer F, McBurney MW, de Murcia G, Sassone-Corsi P. 2006. Control of AIF-mediated cell death by the functional interplay of SIRT1 and PARP-1 in response to DNA damage. Cell Cycle 5: 873-877. (Pubitemid 44145583)
-
(2006)
Cell Cycle
, vol.5
, Issue.8
, pp. 873-877
-
-
Kolthur-Seetharam, U.1
Dantzer, F.2
McBurney, M.W.3
De Murcia, G.4
Sassone-Corsi, P.5
-
77
-
-
0037331390
-
H2O2-induced higher order chromatin degradation: A novel mechanism of oxidative genotoxicity
-
Konat GW. 2003. H2O2-induced higher order chromatin degradation: A novel mechanism of oxidative genotoxicity. J Biosci 28: 57-60.
-
(2003)
J Biosci
, vol.28
, pp. 57-60
-
-
Konat, G.W.1
-
78
-
-
44649130038
-
Transcriptional control by PARP-1: Chromatin modulation, enhancer-binding, coregulation, and insulation
-
Kraus WL. 2008. Transcriptional control by PARP-1: Chromatin modulation, enhancer-binding, coregulation, and insulation. Curr Opin Cell Biol 20: 294-302.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 294-302
-
-
Kraus, W.L.1
-
79
-
-
0036810314
-
+-regulated dehydrogenase
-
+-regulated dehydrogenase. Mol Cell 10: 857-869.
-
(2002)
Mol Cell
, vol.10
, pp. 857-869
-
-
Kumar, V.1
Carlson, J.E.2
Ohgi, K.A.3
Edwards, T.A.4
Rose, D.W.5
Escalante, C.R.6
Rosenfeld, M.G.7
Aggarwal, A.K.8
-
80
-
-
22144437998
-
Splicing regulates NAD metabolite binding to histone macroH2A
-
DOI 10.1038/nsmb956
-
Kustatscher G, Hothorn M, Pugieux C, Scheffzek K, Ladurner AG. 2005. Splicing regulates NAD metabolite binding to histone macroH2A. Nat Struct Mol Biol 12: 624-625. (Pubitemid 40980814)
-
(2005)
Nature Structural and Molecular Biology
, vol.12
, Issue.7
, pp. 624-625
-
-
Kustatscher, G.1
Hothorn, M.2
Pugieux, C.3
Scheffzek, K.4
Ladurner, A.G.5
-
81
-
-
1942502862
-
Different Ezh2-containing complexes target methylation of histone H1 or nucleosomal histone H3
-
DOI 10.1016/S1097-2765(04)00185-6, PII S1097276504001856
-
Kuzmichev A, Jenuwein T, Tempst P, Reinberg D. 2004. Different EZH2-containing complexes target methylation of histone H1 or nucleosomal histone H3. Mol Cell 14: 183-193. (Pubitemid 38515646)
-
(2004)
Molecular Cell
, vol.14
, Issue.2
, pp. 183-193
-
-
Kuzmichev, A.1
Jenuwein, T.2
Tempst, P.3
Reinberg, D.4
-
82
-
-
13844315463
-
Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation
-
Kuzmichev A, Margueron R, Vaquero A, Preissner TS, Scher M, Kirmizis A, Ouyang X, Brockdorff N, Abate-Shen C, Farnham P, et al. 2005. Composition and histone substrates of polycomb repressive group complexes change during cellular differentiation. Proc Natl Acad Sci 102: 1859-1864.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 1859-1864
-
-
Kuzmichev, A.1
Margueron, R.2
Vaquero, A.3
Preissner, T.S.4
Scher, M.5
Kirmizis, A.6
Ouyang, X.7
Brockdorff, N.8
Abate-Shen, C.9
Farnham, P.10
-
83
-
-
55549096745
-
SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation
-
Lan F, Cacicedo JM, Ruderman N, Ido Y. 2008. SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation. J Biol Chem 283: 27628-27635.
-
(2008)
J Biol Chem
, vol.283
, pp. 27628-27635
-
-
Lan, F.1
Cacicedo, J.M.2
Ruderman, N.3
Ido, Y.4
-
84
-
-
41549138483
-
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
-
Lee IH, Cao L, Mostoslavsky R, Lombard DB, Liu J, Bruns NE, Tsokos M, Alt FW, Finkel T. 2008. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc Natl Acad Sci 105: 3374-3379.
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 3374-3379
-
-
Lee, I.H.1
Cao, L.2
Mostoslavsky, R.3
Lombard, D.B.4
Liu, J.5
Bruns, N.E.6
Tsokos, M.7
Alt, F.W.8
Finkel, T.9
-
85
-
-
10744230544
-
Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin
-
DOI 10.1016/S0960-9822(03)00432-9
-
Lehnertz B, Ueda Y, Derijck AA, Braunschweig U, Perez-Burgos L, Kubicek S, Chen T, Li E, Jenuwein T, Peters AH. 2003. Suv39h-mediated histone H3 lysine 9 methylation directs DNA methylation to major satellite repeats at pericentric heterochromatin. Curr Biol 13: 1192-1200. (Pubitemid 36872941)
-
(2003)
Current Biology
, vol.13
, Issue.14
, pp. 1192-1200
-
-
Lehnertz, B.1
Ueda, Y.2
Derijck, A.A.H.A.3
Braunschweig, U.4
Perez-Burgos, L.5
Kubicek, S.6
Chen, T.7
Li, E.8
Jenuwein, T.9
Peters, A.H.F.M.10
-
86
-
-
27644534576
-
The response of autologous T cells to a human melanoma is dominated by mutated neoantigens
-
Lennerz V, Fatho M, Gentilini C, Frye RA, Lifke A, Ferel D, Wolfel C, Huber C, Wolfel T. 2005. The response of autologous T cells to a human melanoma is dominated by mutated neoantigens. Proc Natl Acad Sci 102: 16013-16018.
-
(2005)
Proc Natl Acad Sci
, vol.102
, pp. 16013-16018
-
-
Lennerz, V.1
Fatho, M.2
Gentilini, C.3
Frye, R.A.4
Lifke, A.5
Ferel, D.6
Wolfel, C.7
Huber, C.8
Wolfel, T.9
-
87
-
-
33748298941
-
Nutrient regulates Tor1 nuclear localization and association with rDNA promoter
-
DOI 10.1038/nature05020, PII NATURE05020
-
Li H, Tsang CK, Watkins M, Bertram PG, Zheng XF. 2006. Nutrient regulates Tor1 nuclear localization and association with rDNA promoter. Nature 442: 1058-1061. (Pubitemid 44330265)
-
(2006)
Nature
, vol.442
, Issue.7106
, pp. 1058-1061
-
-
Li, H.1
Tsang, C.K.2
Watkins, M.3
Bertram, P.G.4
Zheng, X.F.S.5
-
88
-
-
34948883324
-
SIRT1 Deacetylates and Positively Regulates the Nuclear Receptor LXR
-
DOI 10.1016/j.molcel.2007.07.032, PII S109727650700620X
-
Li X, Zhang S, Blander G, Tse JG, Krieger M, Guarente L. 2007. SIRT1 deacetylates and positively regulates the nuclear receptor LXR. Mol Cell 28: 91-106. (Pubitemid 47531974)
-
(2007)
Molecular Cell
, vol.28
, Issue.1
, pp. 91-106
-
-
Li, X.1
Zhang, S.2
Blander, G.3
Tse, J.G.4
Krieger, M.5
Guarente, L.6
-
89
-
-
0037130175
-
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
-
DOI 10.1038/nature00829
-
Lin SJ, Kaeberlein M, Andalis AA, Sturtz LA, Defossez PA, Culotta VC, Fink GR, Guarente L. 2002. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 418: 344-348. (Pubitemid 34790687)
-
(2002)
Nature
, vol.418
, Issue.6895
, pp. 344-348
-
-
Lin, S.-J.1
Kaeberlein, M.2
Andalis, A.A.3
Sturtz, L.A.4
Defossez, P.-A.5
Culotta, V.C.6
Fink, G.R.7
Guarente, L.8
-
90
-
-
20444409132
-
Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase
-
DOI 10.1074/jbc.M413296200
-
Liszt G, Ford E, Kurtev M, Guarente L. 2005. Mouse Sir2 homolog SIRT6 is a nuclear ADP-ribosyltransferase. J Biol Chem 280: 21313-21320. (Pubitemid 40805693)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.22
, pp. 21313-21320
-
-
Liszt, G.1
Ford, E.2
Kurtev, M.3
Guarente, L.4
-
91
-
-
37549002891
-
Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation
-
Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, et al. 2007. Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation. Mol Cell Biol 27: 8807-8814.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 8807-8814
-
-
Lombard, D.B.1
Alt, F.W.2
Cheng, H.L.3
Bunkenborg, J.4
Streeper, R.S.5
Mostoslavsky, R.6
Kim, J.7
Yancopoulos, G.8
Valenzuela, D.9
Murphy, A.10
-
92
-
-
32444437067
-
Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency
-
DOI 10.1073/pnas.0510452103
-
Lopez-Lluch G, Hunt N, Jones B, Zhu M, Jamieson H, Hilmer S, Cascajo MV, Allard J, Ingram DK, Navas P, et al. 2006. Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency. Proc Natl Acad Sci 103: 1768-1773. (Pubitemid 43228768)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.6
, pp. 1768-1773
-
-
Lopez-Lluch, G.1
Hunt, N.2
Jones, B.3
Zhu, M.4
Jamieson, H.5
Hilmer, S.6
Cascajo, M.V.7
Allard, J.8
Ingram, D.K.9
Navas, P.10
De Cabo, R.11
-
93
-
-
0035913911
-
Negative control of p53 by Sir2α promotes cell survival under stress
-
DOI 10.1016/S0092-8674(01)00524-4
-
Luo J, Nikolaev AY, Imai S, Chen D, Su F, Shiloh A, Guarente L, Gu W. 2001. Negative control of p53 by Sir2α promotes cell survival under stress. Cell 107: 137-148. (Pubitemid 33035941)
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.-I.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
94
-
-
48749098341
-
SIRT2 is a negative regulator of anoxia-reoxygenation tolerance via regulation of 14-3-3 ζ and BAD in H9c2 cells
-
Lynn EG, McLeod CJ, Gordon JP, Bao J, Sack MN. 2008. SIRT2 is a negative regulator of anoxia-reoxygenation tolerance via regulation of 14-3-3 ζ and BAD in H9c2 cells. FEBS Lett 582: 2857-2862.
-
(2008)
FEBS Lett
, vol.582
, pp. 2857-2862
-
-
Lynn, E.G.1
McLeod, C.J.2
Gordon, J.P.3
Bao, J.4
Sack, M.N.5
-
95
-
-
34047099212
-
GCIP/CCNDBP1, a helix-loop-helix protein, suppresses tumorigenesis
-
DOI 10.1002/jcb.21140
-
Ma W, Stafford LJ, Li D, Luo J, Li X, Ning G, Liu M. 2007. GCIP/CCNDBP1, a helix-loop-helix protein, suppresses tumorigenesis. J Cell Biochem 100: 1376-1386. (Pubitemid 46515572)
-
(2007)
Journal of Cellular Biochemistry
, vol.100
, Issue.6
, pp. 1376-1386
-
-
Ma, W.1
Stafford, L.J.2
Li, D.3
Luo, J.4
Li, X.5
Ning, G.6
Liu, M.7
-
96
-
-
0031984854
-
Hormesis and the antiaging action of dietary restriction
-
DOI 10.1016/S0531-5565(97)00071-5, PII S0531556597000715
-
Masoro EJ. 1998. Hormesis and the antiaging action of dietary restriction. Exp Gerontol 33: 61-66. (Pubitemid 28027633)
-
(1998)
Experimental Gerontology
, vol.33
, Issue.1-2
, pp. 61-66
-
-
Masoro, E.J.1
-
97
-
-
22744445281
-
Overview of caloric restriction and ageing
-
Masoro EJ. 2005. Overview of caloric restriction and ageing. Mech Ageing Dev 126: 913-922.
-
(2005)
Mech Ageing Dev
, vol.126
, pp. 913-922
-
-
Masoro, E.J.1
-
98
-
-
0037207475
-
The mammalian SIR2α protein has a role in embryogenesis and gametogenesis
-
DOI 10.1128/MCB.23.1.38-54.2003
-
McBurney MW, Yang X, Jardine K, Hixon M, Boekelheide K, Webb JR, Lansdorp PM, Lemieux M. 2003. The mammalian SIR2α protein has a role in embryogenesis and gametogenesis. Mol Cell Biol 23: 38-54. (Pubitemid 36008499)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.1
, pp. 38-54
-
-
McBurney, M.W.1
Yang, X.2
Jardine, K.3
Hixon, M.4
Boekelheide, K.5
Webb, J.R.6
Lansdorp, P.M.7
Lemieux, M.8
-
99
-
-
0002458132
-
The effect of retarded growth upon the length of life span and upon the ultimate body size
-
McCay CM, Crowell MF, Maynard LA. 1935. The effect of retarded growth upon the length of life span and upon the ultimate body size. J Nutr 10: 63-79.
-
(1935)
J Nutr
, vol.10
, pp. 63-79
-
-
McCay, C.M.1
Crowell, M.F.2
Maynard, L.A.3
-
100
-
-
35648995939
-
MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae
-
DOI 10.1371/journal.pbio.0050261
-
Medvedik O, Lamming DW, Kim KD, Sinclair DA. 2007. MSN2 and MSN4 link calorie restriction and TOR to sirtuin-mediated lifespan extension in Saccharomyces cerevisiae. PLoS Biol 5: e261. doi: 10.1371/journal.pbio.0050261. (Pubitemid 350035432)
-
(2007)
PLoS Biology
, vol.5
, Issue.10
, pp. 2330-2341
-
-
Medvedik, O.1
Lamming, D.W.2
Kim, K.D.3
Sinclair, D.A.4
-
101
-
-
26244436281
-
Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins
-
DOI 10.1091/mbc.E05-01-0033
-
Michishita E, Park JY, Burneskis JM, Barrett JC, Horikawa I. 2005. Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol Biol Cell 16: 4623-4635. (Pubitemid 41416446)
-
(2005)
Molecular Biology of the Cell
, vol.16
, Issue.10
, pp. 4623-4635
-
-
Michishita, E.1
Park, J.Y.2
Burneskis, J.M.3
Barrett, J.C.4
Horikawa, I.5
-
102
-
-
41349090663
-
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
-
Michishita E, McCord RA, Berber E, Kioi M, Padilla-Nash H, Damian M, Cheung P, Kusumoto R, Kawahara TL, Barrett JC, et al. 2008. SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature 452: 492-496.
-
(2008)
Nature
, vol.452
, pp. 492-496
-
-
Michishita, E.1
McCord, R.A.2
Berber, E.3
Kioi, M.4
Padilla-Nash, H.5
Damian, M.6
Cheung, P.7
Kusumoto, R.8
Kawahara, T.L.9
Barrett, J.C.10
-
103
-
-
0036829968
-
Structure of the SET domain histone lysine methyltransferase Clr4
-
Min J, Zhang X, Cheng X, Grewal SI, Xu RM. 2002. Structure of the SET domain histone lysine methyltransferase Clr4. Nat Struct Biol 9: 828-832. (Pubitemid 35257782)
-
(2002)
Nature Structural Biology
, vol.9
, Issue.11
, pp. 828-832
-
-
Min, J.1
Zhang, X.2
Cheng, X.3
Grewal, S.I.S.4
Xu, R.-M.5
-
104
-
-
0038714732
-
Hdm2 recruits a hypoxia-sensitive corepressor to negatively regulate p53-dependent transcription
-
DOI 10.1016/S0960-9822(03)00454-8
-
Mirnezami AH, Campbell SJ, Darley M, Primrose JN, Johnson PW, Blaydes JP. 2003. Hdm2 recruits a hypoxia-sensitive corepressor to negatively regulate p53-dependent transcription. Curr Biol 13: 1234-1239. (Pubitemid 36872947)
-
(2003)
Current Biology
, vol.13
, Issue.14
, pp. 1234-1239
-
-
Mirnezami, A.H.1
Campbell, S.J.2
Darley, M.3
Primrose, J.N.4
Johnson, P.W.M.5
Blaydes, J.P.6
-
105
-
-
33845451723
-
Ros-induced histone modifications and their role in cell survival and cell death
-
DOI 10.1080/03602530600959649, PII RR1270M733784484
-
Monks TJ, Xie R, Tikoo K, Lau SS. 2006. Ros-induced histone modifications and their role in cell survival and cell death. Drug Metab Rev 38: 755-767. (Pubitemid 44903267)
-
(2006)
Drug Metabolism Reviews
, vol.38
, Issue.4
, pp. 755-767
-
-
Monks, T.J.1
Xie, R.2
Tikoo, K.3
Lau, S.S.4
-
106
-
-
31044445366
-
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
-
DOI 10.1016/j.cell.2005.11.044, PII S0092867406000493
-
Mostoslavsky R, Chua KF, Lombard DB, Pang WW, Fischer MR, Gellon L, Liu P, Mostoslavsky G, Franco S, Murphy MM, et al. 2006. Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell 124: 315-329. (Pubitemid 43121980)
-
(2006)
Cell
, vol.124
, Issue.2
, pp. 315-329
-
-
Mostoslavsky, R.1
Chua, K.F.2
Lombard, D.B.3
Pang, W.W.4
Fischer, M.R.5
Gellon, L.6
Liu, P.7
Mostoslavsky, G.8
Franco, S.9
Murphy, M.M.10
Mills, K.D.11
Patel, P.12
Hsu, J.T.13
Hong, A.L.14
Ford, E.15
Cheng, H.-L.16
Kennedy, C.17
Nunez, N.18
Bronson, R.19
Frendewey, D.20
Auerbach, W.21
Valenzuela, D.22
Karow, M.23
Hottiger, M.O.24
Hursting, S.25
Barrett, J.C.26
Guarente, L.27
Mulligan, R.28
Demple, B.29
Yancopoulos, G.D.30
Alt, F.W.31
more..
-
107
-
-
1342264308
-
Mammalian SIRT1 Represses Forkhead Transcription Factors
-
DOI 10.1016/S0092-8674(04)00126-6
-
Motta MC, Divecha N, Lemieux M, Kamel C, Chen D, Gu W, Bultsma Y, McBurney M, Guarente L. 2004. Mammalian SIRT1 represses forkhead transcription factors. Cell 116: 551-563. (Pubitemid 38264432)
-
(2004)
Cell
, vol.116
, Issue.4
, pp. 551-563
-
-
Motta, M.C.1
Divecha, N.2
Lemieux, M.3
Kamel, C.4
Chen, D.5
Gu, W.6
Bultsma, Y.7
McBurney, M.8
Guarente, L.9
-
108
-
-
25144454432
-
Increased dosage of mammalian Sir2 in pancreatic β cells enhances glucose-stimulated insulin secretion in mice
-
Moynihan KA, Grimm AA, Plueger MM, Bernal-Mizrachi E, Ford E, Cras-Meneur C, Permutt MA, Imai S. 2005. Increased dosage of mammalian Sir2 in pancreatic β cells enhances glucose-stimulated insulin secretion in mice. Cell Metab 2: 105-117.
-
(2005)
Cell Metab
, vol.2
, pp. 105-117
-
-
Moynihan, K.A.1
Grimm, A.A.2
Plueger, M.M.3
Bernal-Mizrachi, E.4
Ford, E.5
Cras-Meneur, C.6
Permutt, M.A.7
Imai, S.8
-
109
-
-
43049169926
-
Epigenetic Control of rDNA Loci in Response to Intracellular Energy Status
-
DOI 10.1016/j.cell.2008.03.030, PII S0092867408004595
-
Murayama A, Ohmori K, Fujimura A, Minami H, Yasuzawa-Tanaka K, Kuroda T, Oie S, Daitoku H, Okuwaki M, Nagata K, et al. 2008. Epigenetic control of rDNA loci in response to intracellular energy status. Cell 133: 627-639. (Pubitemid 351636301)
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 627-639
-
-
Murayama, A.1
Ohmori, K.2
Fujimura, A.3
Minami, H.4
Yasuzawa-Tanaka, K.5
Kuroda, T.6
Oie, S.7
Daitoku, H.8
Okuwaki, M.9
Nagata, K.10
Fukamizu, A.11
Kimura, K.12
Shimizu, T.13
Yanagisawa, J.14
-
110
-
-
37349100520
-
The FoxO transcription factors and metabolic regulation
-
DOI 10.1016/j.febslet.2007.11.025, PII S0014579307011696
-
Nakae J, Oki M, Cao Y. 2008. The FoxO transcription factors and metabolic regulation. FEBS Lett 582: 54-67. (Pubitemid 350297245)
-
(2008)
FEBS Letters
, vol.582
, Issue.1
, pp. 54-67
-
-
Nakae, J.1
Oki, M.2
Cao, Y.3
-
111
-
-
47549088250
-
+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control
-
DOI 10.1016/j.cell.2008.07.002, PII S0092867408008799
-
Nakahata Y, Kaluzova M, Grimaldi B, Sahar S, Hirayama J, Chen D, Guarente LP, Sassone-Corsi P. 2008. The NAD+-dependent deacetylase SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control. Cell 134: 329-340. (Pubitemid 352010336)
-
(2008)
Cell
, vol.134
, Issue.2
, pp. 329-340
-
-
Nakahata, Y.1
Kaluzova, M.2
Grimaldi, B.3
Sahar, S.4
Hirayama, J.5
Chen, D.6
Guarente, L.P.7
Sassone-Corsi, P.8
-
113
-
-
37549026223
-
Localization of mouse mitochondrial SIRT proteins: Shift of SIRT3 to nucleus by co-expression with SIRT5
-
DOI 10.1016/j.bbrc.2007.11.122, PII S0006291X07025338
-
Nakamura Y, Ogura M, Tanaka D, Inagaki N. 2008. Localization of mouse mitochondrial SIRT proteins: Shift of SIRT3 to nucleus by co-expression with SIRT5. Biochem Biophys Res Commun 366: 174-179. (Pubitemid 50010675)
-
(2008)
Biochemical and Biophysical Research Communications
, vol.366
, Issue.1
, pp. 174-179
-
-
Nakamura, Y.1
Ogura, M.2
Tanaka, D.3
Inagaki, N.4
-
114
-
-
26844558334
-
Cell biology: Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
-
DOI 10.1126/science.1117728
-
Nisoli E, Tonello C, Cardile A, Cozzi V, Bracale R, Tedesco L, Falcone S, Valerio A, Cantoni O, Clementi E, et al. 2005. Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science 310: 314-317. (Pubitemid 41457197)
-
(2005)
Science
, vol.310
, Issue.5746
, pp. 314-317
-
-
Nisoli, E.1
Tonello, C.2
Cardile, A.3
Cozzi, V.4
Bracale, R.5
Tedesco, L.6
Falcone, S.7
Valerio, A.8
Cantoni, O.9
Clementi, E.10
Moncada, S.11
Carruba, M.O.12
-
115
-
-
34547098165
-
Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation
-
DOI 10.1074/jbc.M702990200
-
North BJ, Verdin E. 2007. Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation. J Biol Chem 282: 19546-19555. (Pubitemid 47100062)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.27
, pp. 19546-19555
-
-
North, B.J.1
Verdin, E.2
-
117
-
-
56749156405
-
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
-
Oberdoerffer P, Michan S, McVay M, Mostoslavsky R, Vann J, Park SK, Hartlerode A, Stegmuller J, Hafner A, Loerch P, et al. 2008. SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell 135: 907-918.
-
(2008)
Cell
, vol.135
, pp. 907-918
-
-
Oberdoerffer, P.1
Michan, S.2
McVay, M.3
Mostoslavsky, R.4
Vann, J.5
Park, S.K.6
Hartlerode, A.7
Stegmuller, J.8
Hafner, A.9
Loerch, P.10
-
118
-
-
50849104569
-
Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island
-
doi: 10.1371/journal.pgen.1000155
-
O'Hagan HM, Mohammad HP, Baylin SB. 2008. Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island. PLoS Genet 4: e1000155. doi: 10.1371/journal. pgen.1000155.
-
(2008)
PLoS Genet
, vol.4
-
-
O'Hagan, H.M.1
Mohammad, H.P.2
Baylin, S.B.3
-
119
-
-
0037108799
-
SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria
-
Onyango P, Celic I, McCaffery JM, Boeke JD, Feinberg AP. 2002. SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria. Proc Natl Acad Sci 99: 13653-13658.
-
(2002)
Proc Natl Acad Sci
, vol.99
, pp. 13653-13658
-
-
Onyango, P.1
Celic, I.2
McCaffery, J.M.3
Boeke, J.D.4
Feinberg, A.P.5
-
120
-
-
33845445006
-
The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activity
-
DOI 10.1101/gad.396106
-
Ouararhni K, Hadj-Slimane R, Ait-Si-Ali S, Robin P, Mietton F, Harel-Bellan A, Dimitrov S, Hamiche A. 2006. The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activity. Genes & Dev 20: 3324-3336. (Pubitemid 44904853)
-
(2006)
Genes and Development
, vol.20
, Issue.23
, pp. 3324-3336
-
-
Ouararhni, K.1
Hadj-Slimane, R.2
Ait-Si-Ali, S.3
Robin, P.4
Mietton, F.5
Harel-Bellan, A.6
Dimitrov, S.7
Hamiche, A.8
-
121
-
-
34547599329
-
Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson's disease
-
DOI 10.1126/science.1143780
-
Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC, McLean PJ, et al. 2007. Sirtuin 2 inhibitors rescue α-synuclein-mediated toxicity in models of Parkinson's disease. Science 317: 516-519. (Pubitemid 47196116)
-
(2007)
Science
, vol.317
, Issue.5837
, pp. 516-519
-
-
Outeiro, T.F.1
Kontopoulos, E.2
Altmann, S.M.3
Kufareva, I.4
Strathearn, K.E.5
Amore, A.M.6
Volk, C.B.7
Maxwell, M.M.8
Rochet, J.-C.9
McLean, P.J.10
Young, A.B.11
Abagyan, R.12
Feany, M.B.13
Hyman, B.T.14
Kazantsev, A.G.15
-
122
-
-
17944380227
-
Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability
-
DOI 10.1016/S0092-8674(01)00542-6
-
Peters AH, O'Carroll D, Scherthan H, Mechtler K, Sauer S, Schofer C, Weipoltshammer K, Pagani M, Lachner M, Kohlmaier A, et al. 2001. Loss of the Suv39h histone methyltransferases impairs mammalian heterochromatin and genome stability. Cell 107: 323-337. (Pubitemid 33049976)
-
(2001)
Cell
, vol.107
, Issue.3
, pp. 323-337
-
-
Peters, A.H.F.M.1
O'Carroll, D.2
Scherthan, H.3
Mechtler, K.4
Sauer, S.5
Schofer, C.6
Weipoltshammer, K.7
Pagani, M.8
Lachner, M.9
Kohlmaier, A.10
Opravil, S.11
Doyle, M.12
Sibilia, M.13
Jenuwein, T.14
-
123
-
-
0031821009
-
Preferential accumulation of single-stranded regions in telomeres of human fibroblasts
-
DOI 10.1006/excr.1997.3893
-
Petersen S, Saretzki G, von Zglinicki T. 1998. Preferential accumulation of single-stranded regions in telomeres of human fibroblasts. Exp Cell Res 239: 152-160. (Pubitemid 28368486)
-
(1998)
Experimental Cell Research
, vol.239
, Issue.1
, pp. 152-160
-
-
Petersen, S.1
Saretzki, G.2
Von Zglinicki, T.3
-
124
-
-
3042681042
-
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ
-
DOI 10.1038/nature02583
-
Picard F, Kurtev M, Chung N, Topark-Ngarm A, Senawong T, Machado De Oliveira R, Leid M, McBurney MW, Guarente L. 2004. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ. Nature 429: 771-776. (Pubitemid 38833129)
-
(2004)
Nature
, vol.429
, Issue.6993
, pp. 771-776
-
-
Picard, F.1
Kurtev, M.2
Chung, N.3
Topark-Ngarm, A.4
Senawong, T.5
De Oliveira, R.M.6
Leid, M.7
McBurney, M.W.8
Guarente, L.9
-
125
-
-
0036261826
-
The diversity of acetylated proteins
-
reviews0006. doi: 10.1186/gb-2002-3-5-reviews0006
-
Polevodan, B. and F. Sherman. 2002. The diversity of acetylated proteins. Genome Biol 3: reviews0006. doi: 10.1186/gb-2002-3-5-reviews0006.
-
(2002)
Genome Biol
, vol.3
-
-
Polevodan, B.1
Sherman, F.2
-
126
-
-
42349085704
-
Sirt1 contributes critically to the redox-dependent fate of neural progenitors
-
Prozorovski T, Schulze-Topphoff U, Glumm R, Baumgart J, Schroter F, Ninnemann O, Siegert E, Bendix I, Brustle O, Nitsch R, et al. 2008. Sirt1 contributes critically to the redox-dependent fate of neural progenitors. Nat Cell Biol 10: 385-394.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 385-394
-
-
Prozorovski, T.1
Schulze-Topphoff, U.2
Glumm, R.3
Baumgart, J.4
Schroter, F.5
Ninnemann, O.6
Siegert, E.7
Bendix, I.8
Brustle, O.9
Nitsch, R.10
-
127
-
-
33645768490
-
Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation
-
doi: 10.1371/journal.pgen.0020040
-
Pruitt K, Zinn RL, Ohm JE, McGarvey KM, Kang SH, Watkins DN, Herman JG, Baylin SB. 2006. Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation. PLoS Genet 2: e40. doi: 10.1371/journal.pgen.0020040.
-
(2006)
PLoS Genet
, vol.2
-
-
Pruitt, K.1
Zinn, R.L.2
Ohm, J.E.3
McGarvey, K.M.4
Kang, S.H.5
Watkins, D.N.6
Herman, J.G.7
Baylin, S.B.8
-
128
-
-
33644779774
-
Nutrient availability and growth: Regulation of insulin signaling by dFOXO/FOXO1
-
Puig O, Tjian R. 2006. Nutrient availability and growth: Regulation of insulin signaling by dFOXO/FOXO1. Cell Cycle 5: 503-505. (Pubitemid 43340527)
-
(2006)
Cell Cycle
, vol.5
, Issue.5
, pp. 503-505
-
-
Puig, O.1
Tjian, R.2
-
130
-
-
58349083304
-
Endocrine alterations in response to calorie restriction in humans
-
Redman LM, Ravussin E. 2009. Endocrine alterations in response to calorie restriction in humans. Mol Cell Endocrinol 299: 129-136.
-
(2009)
Mol Cell Endocrinol
, vol.299
, pp. 129-136
-
-
Redman, L.M.1
Ravussin, E.2
-
131
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
-
DOI 10.1038/nature03354
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. 2005. Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1. Nature 434: 113-118. (Pubitemid 40349395)
-
(2005)
Nature
, vol.434
, Issue.7029
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
132
-
-
8644224064
-
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
-
Rogina B, Helfand SL. 2004. Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc Natl Acad Sci 101: 15998-16003.
-
(2004)
Proc Natl Acad Sci
, vol.101
, pp. 15998-16003
-
-
Rogina, B.1
Helfand, S.L.2
-
133
-
-
0037223438
-
The tor pathway regulates gene expression by linking nutrient sensing to histone acetylation
-
Rohde JR, Cardenas ME. 2003. The tor pathway regulates gene expression by linking nutrient sensing to histone acetylation. Mol Cell Biol 23: 629-635.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 629-635
-
-
Rohde, J.R.1
Cardenas, M.E.2
-
134
-
-
34547875773
-
Sirtuins: Critical regulators at the crossroads between cancer and aging
-
DOI 10.1038/sj.onc.1210616, PII 1210616
-
Saunders LR, Verdin E. 2007. Sirtuins: Critical regulators at the crossroads between cancer and aging. Oncogene 26: 5489-5504. (Pubitemid 47255930)
-
(2007)
Oncogene
, vol.26
, Issue.37
, pp. 5489-5504
-
-
Saunders, L.R.1
Verdin, E.2
-
135
-
-
34247271282
-
+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress
-
+-dependent histone deacetylase that translocates to the mitochondria upon cellular stress. Genes & Dev 21: 920-928.
-
(2007)
Genes & Dev
, vol.21
, pp. 920-928
-
-
Scher, M.B.1
Vaquero, A.2
Reinberg, D.3
-
136
-
-
50149103440
-
Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5
-
Schlicker C, Gertz M, Papatheodorou P, Kachholz B, Becker CF, Steegborn C. 2008. Substrates and regulation mechanisms for the human mitochondrial sirtuins Sirt3 and Sirt5. J Mol Biol 382: 790-801.
-
(2008)
J Mol Biol
, vol.382
, pp. 790-801
-
-
Schlicker, C.1
Gertz, M.2
Papatheodorou, P.3
Kachholz, B.4
Becker, C.F.5
Steegborn, C.6
-
137
-
-
34748850786
-
Glucose Restriction Extends Caenorhabditis elegans Life Span by Inducing Mitochondrial Respiration and Increasing Oxidative Stress
-
DOI 10.1016/j.cmet.2007.08.011, PII S1550413107002562
-
Schulz TJ, Zarse K, Voigt A, Urban N, Birringer M, Ristow M. 2007. Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell Metab 6: 280-293. (Pubitemid 47468090)
-
(2007)
Cell Metabolism
, vol.6
, Issue.4
, pp. 280-293
-
-
Schulz, T.J.1
Zarse, K.2
Voigt, A.3
Urban, N.4
Birringer, M.5
Ristow, M.6
-
138
-
-
0037135972
-
The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase
-
DOI 10.1083/jcb.200205057
-
Schwer B, North BJ, Frye RA, Ott M, Verdin E. 2002. The human silent information regulator (Sir)2 homologue hSIRT3 is amitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. J Cell Biol 158: 647-657. (Pubitemid 34920104)
-
(2002)
Journal of Cell Biology
, vol.158
, Issue.4
, pp. 647-657
-
-
Schwer, B.1
North, B.J.2
Frye, R.A.3
Ott, M.4
Verdin, E.5
-
139
-
-
33745889628
-
Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2
-
DOI 10.1073/pnas.0603968103
-
Schwer B, Bunkenborg J, Verdin RO, Andersen JS, Verdin E. 2006. Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2. Proc Natl Acad Sci 103: 10224-10229. (Pubitemid 44051148)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.27
, pp. 10224-10229
-
-
Schwer, B.1
Bunkenborg, J.2
Verdin, R.O.3
Andersen, J.S.4
Verdin, E.5
-
140
-
-
0038714132
-
Sir2 regulates histone H3 lysine 9 methylation and heterochromatin assembly in fission yeast
-
DOI 10.1016/S0960-9822(03)00489-5
-
Shankaranarayana GD, Motamedi MR, Moazed D, Grewal SI. 2003. Sir2 regulates histone H3 lysine 9 methylation and heterochromatin assembly in fission yeast. Curr Biol 13: 1240-1246. (Pubitemid 36872948)
-
(2003)
Current Biology
, vol.13
, Issue.14
, pp. 1240-1246
-
-
Shankaranarayana, G.D.1
Motamedi, M.R.2
Moazed, D.3
Grewal, S.I.S.4
-
141
-
-
4143147468
-
Metabolic enzymes and coenzymes in transcription - A direct link between metabolism and transcription?
-
Shi Y. 2004. Metabolic enzymes and coenzymes in transcription - A direct link between metabolism and transcription? Trends Genet 20: 445-452.
-
(2004)
Trends Genet
, vol.20
, pp. 445-452
-
-
Shi, Y.1
-
142
-
-
0242669199
-
Coordinated histone modifications mediated by a CtBP co-repressor complex
-
DOI 10.1038/nature01550
-
Shi Y, Sawada J, Sui G, Affar EB, Whetstine JR, Lan F, Ogawa H, Luke MP-S, Nakatani Y, Shi Y. 2003. Coordinated histone modifications mediated by a CtBP co-repressor complex. Nature 422: 735-738. (Pubitemid 36514114)
-
(2003)
Nature
, vol.422
, Issue.6933
, pp. 735-738
-
-
Shi, Y.1
Sawada, J.-I.2
Sui, G.3
Affar, E.B.4
Whetstine, J.R.5
Lan, F.6
Ogawa, H.7
Luke, M.P.-S.8
Nakatani, Y.9
Shi, Y.10
-
143
-
-
17144424946
-
SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes
-
DOI 10.1074/jbc.M414670200
-
Shi T, Wang F, Stieren E, Tong Q. 2005. SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes. J Biol Chem 280: 13560-13567. (Pubitemid 40517248)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.14
, pp. 13560-13567
-
-
Shi, T.1
Wang, F.2
Stieren, E.3
Tong, Q.4
-
144
-
-
23844452781
-
New nuclear functions of the glycolytic protein, glyceraldehyde-3- phosphate dehydrogenase, in mammalian cells
-
Sirover MA. 2005. New nuclear functions of the glycolytic protein, glyceraldehyde-3-phosphate dehydrogenase, in mammalian cells. J Cell Biochem 95: 45-52.
-
(2005)
J Cell Biochem
, vol.95
, pp. 45-52
-
-
Sirover, M.A.1
-
145
-
-
0030038103
-
Oxidative stress, caloric restriction, and aging
-
Sohal RS, Weindruch R. 1996. Oxidative stress, caloric restriction, and aging. Science 273: 59-63. (Pubitemid 26255420)
-
(1996)
Science
, vol.273
, Issue.5271
, pp. 59-63
-
-
Sohal, R.S.1
Weindruch, R.2
-
146
-
-
0028342438
-
Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse
-
DOI 10.1016/0047-6374(94)90104-X
-
Sohal RS, Ku HH, Agarwal S, Forster MJ, Lal H. 1994. Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse. Mech Ageing Dev 74: 121-133. (Pubitemid 124014917)
-
(1994)
Mechanisms of Ageing and Development
, vol.74
, Issue.1-2
, pp. 121-133
-
-
Sohal, R.S.1
Ku, H.-H.2
Agarwal, S.3
Forster, M.J.4
Lal, H.5
-
147
-
-
0027756782
-
Age-related changes in expression and activity of DNA polymerase α: Some effects of dietary restriction
-
Srivastava VK, Miller S, Schroeder MD, Hart RW, Busbee D. 1993. Age-related changes in expression and activity of DNA polymerase α: Some effects of dietary restriction. Mutat Res 295: 265-280. (Pubitemid 24043520)
-
(1993)
Mutation Research - DNAging Genetic Instability and Aging
, vol.295
, Issue.4-6
, pp. 265-280
-
-
Srivastava, V.K.1
Miller, S.2
Schroeder, M.D.3
Hart, R.W.4
Busbee, D.5
-
149
-
-
2442695594
-
Mitochondrial and nuclear DNA base excision repair are affected differently by caloric restriction
-
Stuart JA, Karahalil B, Hogue BA, Souza-Pinto NC, Bohr VA. 2004. Mitochondrial and nuclear DNA base excision repair are affected differently by caloric restriction. FASEB J 18: 595-597.
-
(2004)
FASEB J
, vol.18
, pp. 595-597
-
-
Stuart, J.A.1
Karahalil, B.2
Hogue, B.A.3
Souza-Pinto, N.C.4
Bohr, V.A.5
-
150
-
-
1242294390
-
Rapid Shortening of Telomere Length in Response to Ceramide Involves the Inhibition of Telomere Binding Activity of Nuclear Glyceraldehyde-3-phosphate Dehydrogenase
-
DOI 10.1074/jbc.M310549200
-
Sundararaj KP, Wood RE, Ponnusamy S, Salas AM, Szulc Z, Bielawska A, Obeid LM, Hannun YA, Ogretmen B. 2004. Rapid shortening of telomere length in response to ceramide involves the inhibition of telomere binding activity of nuclear glyceraldehyde-3-phosphate dehydrogenase. J Biol Chem 279: 6152-6162. (Pubitemid 38220648)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.7
, pp. 6152-6162
-
-
Sundararaj, K.P.1
Wood, R.E.2
Ponnusamy, S.3
Salas, A.M.4
Szulc, Z.5
Bielawska, A.6
Obeid, L.M.7
Hannun, Y.A.8
Ogretmen, B.9
-
151
-
-
53549105529
-
SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70
-
Sundaresan NR, Samant SA, Pillai VB, Rajamohan SB, Gupta MP. 2008. SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. Mol Cell Biol 28: 6384-6401.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6384-6401
-
-
Sundaresan, N.R.1
Samant, S.A.2
Pillai, V.B.3
Rajamohan, S.B.4
Gupta, M.P.5
-
152
-
-
22544480772
-
HMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells
-
DOI 10.1128/MCB.25.15.6798-6810.2005
-
Taipale M, Rea S, Richter K, Vilar A, Lichter P, Imhof A, Akhtar A. 2005. hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells. Mol Cell Biol 25: 6798-6810. (Pubitemid 41023250)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.15
, pp. 6798-6810
-
-
Taipale, M.1
Rea, S.2
Richter, K.3
Vilar, A.4
Lichter, P.5
Imhof, A.6
Akhtar, A.7
-
153
-
-
0033598942
-
An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing
-
Tanny JC, Dowd GJ, Huang J, Hilz H, Moazed D. 1999. An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing. Cell 99: 735-745. (Pubitemid 30017644)
-
(1999)
Cell
, vol.99
, Issue.7
, pp. 735-745
-
-
Tanny, J.C.1
Dowd, G.J.2
Huang, J.3
Hilz, H.4
Moazed, D.5
-
154
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
DOI 10.1038/35065638
-
Tissenbaum HA, Guarente L. 2001. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410: 227-230. (Pubitemid 32216597)
-
(2001)
Nature
, vol.410
, Issue.6825
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
155
-
-
0035012606
-
DNA strand break-sensing molecule poly(ADP-Ribose) polymerase cooperates with p53 in telomere function, chromosome stability, and tumor suppression
-
Tong WM, Hande MP, Lansdorp PM, Wang ZQ. 2001. DNA strand break-sensing molecule poly(ADP-Ribose) polymerase cooperates with p53 in telomere function, chromosome stability, and tumor suppression. Mol Cell Biol 21: 4046-4054.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 4046-4054
-
-
Tong, W.M.1
Hande, M.P.2
Lansdorp, P.M.3
Wang, Z.Q.4
-
156
-
-
34948839944
-
Facultative heterochromatin: Is there a distinctive molecular signature?
-
Trojer P, Reinberg D. 2007. Facultative heterochromatin: Is there a distinctive molecular signature? Mol Cell 28: 1-13.
-
(2007)
Mol Cell
, vol.28
, pp. 1-13
-
-
Trojer, P.1
Reinberg, D.2
-
158
-
-
0345305803
-
Chromatin-mediated regulation of nucleolar structure and RNA Pol I localization by TOR
-
DOI 10.1093/emboj/cdg578
-
Tsang CK, Bertram PG, Ai W, Drenan R, Zheng XF. 2003. Chromatin-mediated regulation of nucleolar structure and RNA Pol I localization by TOR. EMBO J 22: 6045-6056. (Pubitemid 37463248)
-
(2003)
EMBO Journal
, vol.22
, Issue.22
, pp. 6045-6056
-
-
Tsang, C.K.1
Bertram, P.G.2
Ai, W.3
Drenan, R.4
Zheng, X.F.S.5
-
159
-
-
33846542681
-
Nutrient starvation promotes condensin loading to maintain rDNA stability
-
DOI 10.1038/sj.emboj.7601488, PII 7601488
-
Tsang CK, Li H, Zheng XS. 2007a. Nutrient starvation promotes condensin loading to maintain rDNA stability. EMBO J 26: 448-458. (Pubitemid 46160945)
-
(2007)
EMBO Journal
, vol.26
, Issue.2
, pp. 448-458
-
-
Tsang, C.K.1
Li, H.2
Zheng, X.F.S.3
-
160
-
-
35148853473
-
Compacting DNA during the interphase: Condensin maintains rDNA integrity
-
Tsang CK, Wei Y, Zheng XF. 2007b. Compacting DNA during the interphase: Condensin maintains rDNA integrity. Cell Cycle 6: 2213-2218. (Pubitemid 47547695)
-
(2007)
Cell Cycle
, vol.6
, Issue.18
, pp. 2213-2218
-
-
Chi, K.T.1
Wei, Y.2
Zheng, X.F.S.3
-
161
-
-
0036848433
-
Diet, cancer and aging in DNA mismatch repair deficient mice
-
Tsao JL, Dudley S, Kwok B, Nickel AE, Laird PW, Siegmund KD, Liskay RM, Shibata D. 2002. Diet, cancer and aging in DNA mismatch repair deficient mice. Carcinogenesis 23: 1807-1810. (Pubitemid 35355930)
-
(2002)
Carcinogenesis
, vol.23
, Issue.11
, pp. 1807-1810
-
-
Tsao, J.-L.1
Dudley, S.2
Kwok, B.3
Nickel, A.E.4
Laird, P.W.5
Siegmund, K.D.6
Liskay, R.M.7
Shibata, D.8
-
162
-
-
33644777616
-
Drosophila poly(ADP-Ribose) glycohydrolase mediates chromatin structure and SIR2-dependent silencing
-
DOI 10.1534/genetics.105.049239
-
Tulin A, Naumova NM, Menon AK, Spradling AC. 2006. Drosophila poly(ADP-ribose) glycohydrolase mediates chromatin structure and SIR2-dependent silencing. Genetics 172: 363-371. (Pubitemid 43345498)
-
(2006)
Genetics
, vol.172
, Issue.1
, pp. 363-371
-
-
Tulin, A.1
Naumova, N.M.2
Menon, A.K.3
Spradling, A.C.4
-
163
-
-
0141518531
-
Tissue-specific changes of DNA repair protein Ku and mtHSP70 in aging rats and their retardation by caloric restriction
-
Um JH, Kim SJ, Kim DW, Ha MY, Jang JH, Chung BS, Kang CD, Kim SH. 2003. Tissue-specific changes of DNA repair protein Ku and mtHSP70 in aging rats and their retardation by caloric restriction. Mech Ageing Dev 124: 967-975.
-
(2003)
Mech Ageing Dev
, vol.124
, pp. 967-975
-
-
Um, J.H.1
Kim, S.J.2
Kim, D.W.3
Ha, M.Y.4
Jang, J.H.5
Chung, B.S.6
Kang, C.D.7
Kim, S.H.8
-
164
-
-
37349090772
-
Expression and localization of Werner syndrome protein is modulated by SIRT1 and PML
-
DOI 10.1016/j.mad.2007.09.004, PII S0047637407001583
-
Vaitiekunaite R, Butkiewicz D, Krzesniak M, Przybylek M, Gryc A, Snietura M, Benedyk M, Harris CC, Rusin M. 2007. Expression and localization of Werner syndrome protein is modulated by SIRT1 and PML. Mech Ageing Dev 128: 650-661. (Pubitemid 350299048)
-
(2007)
Mechanisms of Ageing and Development
, vol.128
, Issue.11-12
, pp. 650-661
-
-
Vaitiekunaite, R.1
Butkiewicz, D.2
Krzesniak, M.3
Przybylek, M.4
Gryc, A.5
Snietura, M.6
Benedyk, M.7
Harris, C.C.8
Rusin, M.9
-
165
-
-
64049090625
-
Sirt7-dependent inhibition of cell growth and proliferation might be instrumental to mediate tissue integrity during aging
-
Vakhrusheva O, Braeuer D, Liu Z, Braun T, Bober E. 2008a. Sirt7-dependent inhibition of cell growth and proliferation might be instrumental to mediate tissue integrity during aging. J Physiol Pharmacol 59: 201-212.
-
(2008)
J Physiol Pharmacol
, vol.59
, pp. 201-212
-
-
Vakhrusheva, O.1
Braeuer, D.2
Liu, Z.3
Braun, T.4
Bober, E.5
-
166
-
-
41449083867
-
Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice
-
Vakhrusheva O, Smolka C, Gajawada P, Kostin S, Boettger T, Kubin T, Braun T, Bober E. 2008b. Sirt7 increases stress resistance of cardiomyocytes and prevents apoptosis and inflammatory cardiomyopathy in mice. Circ Res 102: 703-710.
-
(2008)
Circ Res
, vol.102
, pp. 703-710
-
-
Vakhrusheva, O.1
Smolka, C.2
Gajawada, P.3
Kostin, S.4
Boettger, T.5
Kubin, T.6
Braun, T.7
Bober, E.8
-
167
-
-
70349138701
-
The conserved role of sirtuins in chromatin regulation
-
Vaquero A. 2009. The conserved role of sirtuins in chromatin regulation. Int J Dev Biol 53: 303-322.
-
(2009)
Int J Dev Biol
, vol.53
, pp. 303-322
-
-
Vaquero, A.1
-
168
-
-
4944245398
-
Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin
-
DOI 10.1016/j.molcel.2004.08.031, PII S1097276504005180
-
Vaquero A, Scher M, Lee D, Erdjument-Bromage H, Tempst P, Reinberg D. 2004. Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin. Mol Cell 16: 93-105. (Pubitemid 39330155)
-
(2004)
Molecular Cell
, vol.16
, Issue.1
, pp. 93-105
-
-
Vaquero, A.1
Scher, M.2
Lee, D.3
Erdjument-Bromage, H.4
Tempst, P.5
Reinberg, D.6
-
169
-
-
33646550204
-
SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis
-
DOI 10.1101/gad.1412706
-
Vaquero A, Scher MB, Lee DH, Sutton A, Cheng HL, Alt FW, Serrano L, Sternglanz R, Reinberg D. 2006. SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis. Genes & Dev 20: 1256-1261. (Pubitemid 43727586)
-
(2006)
Genes and Development
, vol.20
, Issue.10
, pp. 1256-1261
-
-
Vaquero, A.1
Scher, M.B.2
Dong, H.L.3
Sutton, A.4
Cheng, H.-L.5
Alt, F.W.6
Serrano, L.7
Sternglanz, R.8
Reinberg, D.9
-
170
-
-
36248954501
-
SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation
-
DOI 10.1038/nature06268, PII NATURE06268
-
Vaquero A, Scher M, Erdjument-Bromage H, Tempst P, Serrano L, Reinberg D. 2007a. SIRT1 regulates the histone methyltransferase SUV39H1 during heterochromatin formation. Nature 450: 440-444. (Pubitemid 350126745)
-
(2007)
Nature
, vol.450
, Issue.7168
, pp. 440-444
-
-
Vaquero, A.1
Scher, M.2
Erdjument-Bromage, H.3
Tempst, P.4
Serrano, L.5
Reinberg, D.6
-
171
-
-
34547875013
-
+-dependent deacetylation of H4 lysine 16 by class III HDACs
-
DOI 10.1038/sj.onc.1210617, PII 1210617
-
Vaquero A, Sternglanz R, Reinberg D. 2007b. NAD+-dependent deacetylation of H4 lysine 16 by class III HDACs. Oncogene 26: 5505-5520. (Pubitemid 47255931)
-
(2007)
Oncogene
, vol.26
, Issue.37
, pp. 5505-5520
-
-
Vaquero, A.1
Sternglanz, R.2
Reinberg, D.3
-
172
-
-
0035913903
-
SIRT1 functions as an NAD-dependent p53 deacetylase
-
DOI 10.1016/S0092-8674(01)00527-X
-
Vaziri H, Dessain SK, Ng Eaton E, Imai SI, Frye RA, Pandita TK, Guarente L, Weinberg RA. 2001. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107: 149-159. (Pubitemid 33035942)
-
(2001)
Cell
, vol.107
, Issue.2
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Eaton, E.N.3
Imai, S.-I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
173
-
-
0036629255
-
Oxidative stress shortens telomeres
-
von Zglinicki T. 2002. Oxidative stress shortens telomeres. Trends Biochem Sci 27: 339-344.
-
(2002)
Trends Biochem Sci
, vol.27
, pp. 339-344
-
-
Von Zglinicki, T.1
-
174
-
-
64049089450
-
SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARγ
-
Wang F, Tong Q. 2009. SIRT2 suppresses adipocyte differentiation by deacetylating FOXO1 and enhancing FOXO1's repressive interaction with PPARγ. Mol Biol Cell 20: 801-808.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 801-808
-
-
Wang, F.1
Tong, Q.2
-
175
-
-
34447626095
-
SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction
-
DOI 10.1111/j.1474-9726.2007.00304.x
-
Wang F, Nguyen M, Qin FX, Tong Q. 2007. SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction. Aging Cell 6: 505-514. (Pubitemid 47087055)
-
(2007)
Aging Cell
, vol.6
, Issue.4
, pp. 505-514
-
-
Wang, F.1
Nguyen, M.2
Qin, F.X.-F.3
Tong, Q.4
-
176
-
-
53149137486
-
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice
-
Wang RH, Sengupta K, Li C, Kim HS, Cao L, Xiao C, Kim S, Xu X, Zheng Y, Chilton B, et al. 2008. Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell 14: 312-323.
-
(2008)
Cancer Cell
, vol.14
, pp. 312-323
-
-
Wang, R.H.1
Sengupta, K.2
Li, C.3
Kim, H.S.4
Cao, L.5
Xiao, C.6
Kim, S.7
Xu, X.8
Zheng, Y.9
Chilton, B.10
-
177
-
-
33751515840
-
Nuclear export modulates the cytoplasmic Sir2 homologue Hst2
-
DOI 10.1038/sj.embor.7400829, PII 7400829
-
Wilson JM, Le VQ, Zimmerman C, Marmorstein R, Pillus L. 2006. Nuclear export modulates the cytoplasmic Sir2 homologue Hst2. EMBO Rep 7: 1247-1251. (Pubitemid 44835093)
-
(2006)
EMBO Reports
, vol.7
, Issue.12
, pp. 1247-1251
-
-
Wilson, J.M.1
Le, V.Q.2
Zimmerman, C.3
Marmorstein, R.4
Pillus, L.5
-
178
-
-
0028817243
-
Activities of antioxidant enzymes in various tissues of male Fischer 344 rats are altered by food restriction
-
Xia E, Rao G, Van Remmen H, Heydari AR, Richardson A. 1995. Activities of antioxidant enzymes in various tissues of male Fischer 344 rats are altered by food restriction. J Nutr 125: 195-201.
-
(1995)
J Nutr
, vol.125
, pp. 195-201
-
-
Xia, E.1
Rao, G.2
Van Remmen, H.3
Heydari, A.R.4
Richardson, A.5
-
179
-
-
3242719545
-
Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase
-
DOI 10.1038/sj.emboj.7600244
-
Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA, Mayo MW. 2004. Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J 23: 2369-2380. (Pubitemid 38954844)
-
(2004)
EMBO Journal
, vol.23
, Issue.12
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
-
180
-
-
6944231017
-
Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation
-
DOI 10.1038/ng1426
-
Yu W, Ginjala V, Pant V, Chernukhin I, Whitehead J, Docquier F, Farrar D, Tavoosidana G, Mukhopadhyay R, Kanduri C, et al. 2004. Poly(ADP-ribosyl)ation regulates CTCF-dependent chromatin insulation. Nat Genet 36: 1105-1110. (Pubitemid 41184473)
-
(2004)
Nature Genetics
, vol.36
, Issue.10
, pp. 1105-1110
-
-
Yu, W.1
Ginjala, V.2
Pant, V.3
Chernukhin, I.4
Whitehead, J.5
Docquier, F.6
Farrar, D.7
Tavoosidana, G.8
Mukhopadhyay, R.9
Kanduri, C.10
Oshimura, M.11
Feinberg, A.P.12
Lobanenkov, V.13
Klenova, E.14
Ohlsson, R.15
-
181
-
-
34250897968
-
SIRT1 Regulates the Function of the Nijmegen Breakage Syndrome Protein
-
DOI 10.1016/j.molcel.2007.05.029, PII S1097276507003309
-
Yuan Z, Zhang X, Sengupta N, Lane WS, Seto E. 2007. SIRT1 regulates the function of the Nijmegen breakage syndrome protein. Mol Cell 27: 149-162. (Pubitemid 46991383)
-
(2007)
Molecular Cell
, vol.27
, Issue.1
, pp. 149-162
-
-
Yuan, Z.1
Zhang, X.2
Sengupta, N.3
Lane, W.S.4
Seto, E.5
-
182
-
-
0037040581
-
Regulation of corepressor function by nuclear NADH
-
DOI 10.1126/science.1069300
-
Zhang Q, Piston DW, Goodman RH. 2002. Regulation of co-repressor function by nuclear NADH. Science 295: 1895-1897. (Pubitemid 34214127)
-
(2002)
Science
, vol.295
, Issue.5561
, pp. 1895-1897
-
-
Zhang, Q.1
Piston, D.W.2
Goodman, R.H.3
-
183
-
-
33846505019
-
Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex
-
DOI 10.1073/pnas.0610590104
-
Zhang Q, Wang SY, Fleuriel C, Leprince D, Rocheleau JV, Piston DW, Goodman RH. 2007. Metabolic regulation of SIRT1 transcription via a HIC1:CtBP corepressor complex. Proc Natl Acad Sci 104: 829-833. (Pubitemid 46154696)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.3
, pp. 829-833
-
-
Zhang, Q.1
Wang, S.-Y.2
Fleuriel, C.3
Leprince, D.4
Rocheleau, J.V.5
Piston, D.W.6
Goodman, R.H.7
-
184
-
-
0041352962
-
S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component
-
DOI 10.1016/S0092-8674(03)00552-X
-
Zheng L, Roeder RG, Luo Y. 2003. S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key component. Cell 114: 255-266. (Pubitemid 36936918)
-
(2003)
Cell
, vol.114
, Issue.2
, pp. 255-266
-
-
Zheng, L.1
Roeder, R.G.2
Luo, Y.3
|