Insulin-Like Growth Factor-I Receptor Stimulating Activity is Associated with Dementia

Journal of Alzheimer's Disease

Volumn 42, Issue 1, 2014, Pages 137-142

  De Bruijn, Renée F A G ^a   Janssen, Joseph A M J L ^a   Brugts, Michael P ^a   Van Duijn, Cornelia M ^a   Hofman, Albert ^a   Koudstaal, Peter J ^a   Ikram, M Arfan ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Alzheimer's disease; dementia; epidemiology; insulin like growth factor I

Indexed keywords

APOLIPOPROTEIN E4; CHOLESTEROL; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; SOMATOMEDIN C RECEPTOR; APOLIPOPROTEIN E;

AGE; AGED; ALZHEIMER DISEASE; ARTICLE; CHOLESTEROL BLOOD LEVEL; COHORT ANALYSIS; DEMENTIA; DIABETES MELLITUS; FEMALE; FOLLOW UP; GLUCOSE BLOOD LEVEL; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; VERY ELDERLY; WAIST CIRCUMFERENCE; BLOOD; GENETICS; INCIDENCE; LONGITUDINAL STUDY; PREVALENCE; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; RISK; STATISTICAL MODEL;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APOLIPOPROTEINS E; DEMENTIA; FEMALE; FOLLOW-UP STUDIES; HUMANS; INCIDENCE; LOGISTIC MODELS; LONGITUDINAL STUDIES; MALE; PREVALENCE; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RECEPTOR, IGF TYPE 1; RISK;

EID: 84907877754     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-140186     Document Type: Article

References (22)

1. Trejo JL, Carro E, Garcia-Galloway E, Torres-Aleman I (2004) Role of insulin-like growth factor I signaling in neurodegenerative diseases. J Mol Med (Berl) 82, 156-162.
2. Anderson MF, Aberg MA, Nilsson M, Eriksson PS (2002) Insulin-like growth factor-I and neurogenesis in the adult mammalian brain. Brain Res Dev Brain Res 134, 115-122.
3. Carro E, Trejo JL, Gomez-Isla T, LeRoith D, Torres-Aleman I (2002) Serum insulin-like growth factor I regulates brain amyloid-beta levels. Nat Med 8, 1390-1397.
4. Cheng CM, Tseng V, Wang J, Wang D, Matyakhina L, Bondy CA (2005) Tau is hyperphosphorylated in the insulin-like growth factor-I null brain. Endocrinology 146, 5086-5091.
5. Vardy ER, Rice PJ, Bowie PC, Holmes JD, Grant PJ, Hooper NM (2007) Increased circulating insulin-like growth factor-1 in late-onset Alzheimer's disease. J Alzheimers Dis 12, 285-290.
6. Vargas T, Martinez-Garcia A, Antequera D, Vilella E, Clarimon J, Mateo I, Sanchez-Juan P, Rodriguez-Rodriguez E, Frank A, Rosich-Estrago M, Lleo A, Molina-Porcel L, Blesa R, Gomez-Isla T, Combarros O, Bermejo-Pareja F, Valdivieso F, Bullido MJ, Carro E (2011) IGF-I gene variability is associated with an increased risk for AD. Neurobiol Aging 32, 556 e553-511.
7. Salehi Z, Mashayekhi F, Naji M (2008) Insulin like growth factor-1 and insulin like growth factor binding proteins in the cerebrospinal fluid and serum from patients with Alzheimer's disease. Biofactors 33, 99-106.
8. Watanabe T, Miyazaki A, Katagiri T, Yamamoto H, Idei T, Iguchi T (2005) Relationship between serum insulin-like growth factor-1 levels and Alzheimer's disease and vascular dementia. J Am Geriatr Soc 53, 1748-1753.
9. Alvarez A, Cacabelos R, Sanpedro C, Garcia-Fantini M, Aleixandre M (2007) Serum TNF-alpha levels are increased and correlate negatively with free IGF-I in Alzheimer disease. Neurobiol Aging 28, 533-536.
10. Kalmijn S, Janssen JA, Pols HA, Lamberts SW, Breteler MM (2000) A prospective study on circulating insulin-like growth factor I (IGF-I), IGF-binding proteins, and cognitive function in the elderly. J Clin Endocrinol Metab 85, 4551-4555.
11. Chen JW, Ledet T, Orskov H, Jessen N, Lund S, Whittaker J, De Meyts P, Larsen MB, Christiansen JS, Frystyk J (2003) A highly sensitive and specific assay for determination of IGF-I bioactivity in human serum. Am J Physiol Endocrinol Metab 284, E1149-1155.
12. Brugts MP, van Duijn CM, Hofland LJ, Witteman JC, Lamberts SW, Janssen JA (2010) Igf-I bioactivity in an elderly population: Relation to insulin sensitivity, insulin levels, and the metabolic syndrome. Diabetes 59, 505-508.
13. Brugts MP, van den Beld AW, Hofland LJ, van der Wansem K, van Koetsveld PM, Frystyk J, Lamberts SW, Janssen JA (2008) Lowcirculating insulin-like growth factor I bioactivity in elderly men is associated with increased mortality. J Clin Endocrinol Metab 93, 2515-2522.
14. Hofman A, Darwish Murad S, van Duijn CM, Franco OH, Goedegebure A, Ikram MA, Klaver CC, Nijsten TE, Peeters RP, Stricker BH, Tiemeier HW, Uitterlinden AG, Vernooij MW(2013) The Rotterdam Study: 2014 objectives and design update. Eur J Epidemiol 28, 889-926.
15. Janssen JA (2011) Insulin-like growth factor I: Pros and cons of a bioassay. Horm Res Paediatr 76(Suppl 1), 106-110.
16. Brugts MP, Ranke MB, Hofland LJ, van derWansem K, Weber K, Frystyk J, Lamberts SW, Janssen JA (2008) Normal values of circulating insulin-like growth factor-I bioactivity in the healthy population: Comparison with five widely used IGF-I immunoassays. J Clin Endocrinol Metab 93, 2539-2545.
17. Folstein MF, Folstein SE, McHugh PR (1975) "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12, 189-198.
18. Copeland JR, Kelleher MJ, Kellett JM, Gourlay AJ, Gurland BJ, Fleiss JL, Sharpe L (1976) A semi-structured clinical interview for the assessment of diagnosis and mental state in the elderly: The Geriatric Mental State Schedule. I. Development and reliability. Psychol Med 6, 439-449.
19. Roth M, Tym E, Mountjoy CQ, Huppert FA, Hendrie H, Verma S, Goddard R (1986) CAMDEX. A standardised instrument for the diagnosis of mental disorder in the elderly with special reference to the early detection of dementia. Br J Psychiatry 149, 698-709.
20. American Psychiatric Association. Work Group to Revise DSM-III (1987) Diagnostic and Statistical Manual of Mental Disorders: DSM-III-R, 3rd edition. American Psychiatric Association, Washington, DC.
21. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDAWork Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 34, 939-944.
22. Reinhardt RR, Bondy CA (1994) Insulin-like growth factors cross the blood-brain barrier. Endocrinology 135, 1753-1761.