메뉴 건너뛰기




Volumn 503, Issue 1, 2012, Pages 1-11

Gene regulation by melatonin linked to epigenetic phenomena

Author keywords

Cytokines; Epigenetics; Free radicals; Melatonin; Oxidative stress; Transcription

Indexed keywords

CATALASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; CYCLOPHOSPHAMIDE; DEXAMETHASONE; GLUTATHIONE PEROXIDASE; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE PCAF; HISTONE DEACETYLASE; IFOSFAMIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MELATONIN; PROTEIN BAX; PROTEIN BCL 2; RETINOID RELATED ORPHAN RECEPTOR ALPHA; SIRTUIN; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NRF2;

EID: 84861764997     PISSN: 03781119     EISSN: 18790038     Source Type: Journal    
DOI: 10.1016/j.gene.2012.04.040     Document Type: Review
Times cited : (108)

References (176)
  • 1
    • 13244253907 scopus 로고    scopus 로고
    • Redox regulation of histone deacetylases and glucocorticoid-mediated inhibition of the inflammatory response
    • Adcock I.M., Cosio B., Tsaprouni L., Barnes P.J., Ito K. Redox regulation of histone deacetylases and glucocorticoid-mediated inhibition of the inflammatory response. Antioxid. Redox Signal. 2005, 7:144-152.
    • (2005) Antioxid. Redox Signal. , vol.7 , pp. 144-152
    • Adcock, I.M.1    Cosio, B.2    Tsaprouni, L.3    Barnes, P.J.4    Ito, K.5
  • 3
    • 79953726304 scopus 로고    scopus 로고
    • Glucocorticosteroids: current and future directions
    • Barnes P.J. Glucocorticosteroids: current and future directions. Br. J. Pharmacol. 2011, 163:29-43.
    • (2011) Br. J. Pharmacol. , vol.163 , pp. 29-43
    • Barnes, P.J.1
  • 4
    • 0142258702 scopus 로고    scopus 로고
    • Melatonin reduces glial reactivity in the hippocampus, cortex, and cerebellum of streptozotocin-induced diabetic rats
    • Baydas G., Reiter R.J., Yasar A., Tuzcu M., Akdemir I., Nedzvetskii V.S. Melatonin reduces glial reactivity in the hippocampus, cortex, and cerebellum of streptozotocin-induced diabetic rats. Free Radic. Biol. Med. 2003, 35:797-804.
    • (2003) Free Radic. Biol. Med. , vol.35 , pp. 797-804
    • Baydas, G.1    Reiter, R.J.2    Yasar, A.3    Tuzcu, M.4    Akdemir, I.5    Nedzvetskii, V.S.6
  • 6
    • 79952573098 scopus 로고    scopus 로고
    • Reaction mechanism of melatonin oxidation by reactive oxygen species in vitro
    • Bonnefont-Rousselot D., Collin F., Jore D., Gardes-Albert M. Reaction mechanism of melatonin oxidation by reactive oxygen species in vitro. J. Pineal Res. 2011, 50:328-335.
    • (2011) J. Pineal Res. , vol.50 , pp. 328-335
    • Bonnefont-Rousselot, D.1    Collin, F.2    Jore, D.3    Gardes-Albert, M.4
  • 8
    • 1842526076 scopus 로고    scopus 로고
    • Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B
    • Campbell K.J., Rocha S., Perkins N.D. Active repression of antiapoptotic gene expression by RelA(p65) NF-kappa B. Mol. Cell 2004, 13:853-865.
    • (2004) Mol. Cell , vol.13 , pp. 853-865
    • Campbell, K.J.1    Rocha, S.2    Perkins, N.D.3
  • 9
    • 0037389137 scopus 로고    scopus 로고
    • Melatonin counteracts the inhibitory effect of PGE2 on IL-2 production in human lymphocytes via its mt1 membrane receptor
    • Carrillo-Vico A., Garcia-Maurino S., Calvo J.R., Guerrero J.M. Melatonin counteracts the inhibitory effect of PGE2 on IL-2 production in human lymphocytes via its mt1 membrane receptor. FASEB J. 2003, 17:755-757.
    • (2003) FASEB J. , vol.17 , pp. 755-757
    • Carrillo-Vico, A.1    Garcia-Maurino, S.2    Calvo, J.R.3    Guerrero, J.M.4
  • 11
    • 27644466592 scopus 로고    scopus 로고
    • A review of the multiple actions of melatonin on the immune system
    • Carrillo-Vico A., Guerrero J.M., Lardone P.J., Reiter R.J. A review of the multiple actions of melatonin on the immune system. Endocrine 2005, 27:189-200.
    • (2005) Endocrine , vol.27 , pp. 189-200
    • Carrillo-Vico, A.1    Guerrero, J.M.2    Lardone, P.J.3    Reiter, R.J.4
  • 14
    • 0141594607 scopus 로고    scopus 로고
    • Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation
    • Chen L.F., Greene W.C. Regulation of distinct biological activities of the NF-kappaB transcription factor complex by acetylation. J. Mol. Med. 2003, 81:549-557.
    • (2003) J. Mol. Med. , vol.81 , pp. 549-557
    • Chen, L.F.1    Greene, W.C.2
  • 17
    • 33746504821 scopus 로고    scopus 로고
    • Melatonin protects against hydrogen peroxide-induced cell death signaling in SH-SY5Y cultured cells: involvement of nuclear factor kappa B, Bax and Bcl-2
    • Chetsawang B., Putthaprasart C., Phansuwan-Pujito P., Govitrapong P. Melatonin protects against hydrogen peroxide-induced cell death signaling in SH-SY5Y cultured cells: involvement of nuclear factor kappa B, Bax and Bcl-2. J. Pineal Res. 2006, 41:116-123.
    • (2006) J. Pineal Res. , vol.41 , pp. 116-123
    • Chetsawang, B.1    Putthaprasart, C.2    Phansuwan-Pujito, P.3    Govitrapong, P.4
  • 18
    • 79951645465 scopus 로고    scopus 로고
    • Melatonin inhibits Prevotella intermedia lipopolysaccharide-induced production of nitric oxide and interleukin-6 in murine macrophages by suppressing NF-κB and STAT-1 activity
    • Choi E.Y., Jin J.Y., Lee J.Y., Choi H.I., Choi I.S., Kim S.J. Melatonin inhibits Prevotella intermedia lipopolysaccharide-induced production of nitric oxide and interleukin-6 in murine macrophages by suppressing NF-κB and STAT-1 activity. J. Pineal Res. 2011, 50:197-206.
    • (2011) J. Pineal Res. , vol.50 , pp. 197-206
    • Choi, E.Y.1    Jin, J.Y.2    Lee, J.Y.3    Choi, H.I.4    Choi, I.S.5    Kim, S.J.6
  • 19
    • 77953126448 scopus 로고    scopus 로고
    • Molecular targets of epigenetic regulation and effectors of environmental influences
    • Choudhuri S. Molecular targets of epigenetic regulation and effectors of environmental influences. Toxicol. Appl. Pharmacol. 2010, 245:378-393.
    • (2010) Toxicol. Appl. Pharmacol. , vol.245 , pp. 378-393
    • Choudhuri, S.1
  • 20
    • 0030272628 scopus 로고    scopus 로고
    • Effect of melatonin on NF-kappa-B DNA-binding activity in the rat spleen
    • Chuang J.I., Natarajan M., Meltz M.L., Reiter R.J. Effect of melatonin on NF-kappa-B DNA-binding activity in the rat spleen. Cell Biol. Int. 1996, 20:687-692.
    • (1996) Cell Biol. Int. , vol.20 , pp. 687-692
    • Chuang, J.I.1    Natarajan, M.2    Meltz, M.L.3    Reiter, R.J.4
  • 22
    • 34547883918 scopus 로고    scopus 로고
    • Anti-inflammatory functions of glucocorticoid-induced genes
    • Clark A.R. Anti-inflammatory functions of glucocorticoid-induced genes. Mol. Cell. Endocrinol. 2007, 275:79-97.
    • (2007) Mol. Cell. Endocrinol. , vol.275 , pp. 79-97
    • Clark, A.R.1
  • 23
    • 77955123767 scopus 로고    scopus 로고
    • Melatonin prevents the decreased activity of antioxidant enzymes and activates nuclear erythroid 2-related factor 2 signaling in an animal model of fulminant hepatic failure of viral origin
    • Crespo I., Miguel B.S., Laliena A., Alvarez M., Culebras J.M., Gonzalez-Gallego J., Tunon M.J. Melatonin prevents the decreased activity of antioxidant enzymes and activates nuclear erythroid 2-related factor 2 signaling in an animal model of fulminant hepatic failure of viral origin. J. Pineal Res. 2010, 49:193-200.
    • (2010) J. Pineal Res. , vol.49 , pp. 193-200
    • Crespo, I.1    Miguel, B.S.2    Laliena, A.3    Alvarez, M.4    Culebras, J.M.5    Gonzalez-Gallego, J.6    Tunon, M.J.7
  • 24
    • 33748370748 scopus 로고    scopus 로고
    • Effects of combination of melatonin and dexamethasone on acute lung injury in a mice model of carrageenan-induced pleurisy
    • Crisafulli C., Mazzon E., Muia C., Bella P., Esposito E., Meli R., Cuzzocrea S. Effects of combination of melatonin and dexamethasone on acute lung injury in a mice model of carrageenan-induced pleurisy. J. Pineal Res. 2006, 41:228-237.
    • (2006) J. Pineal Res. , vol.41 , pp. 228-237
    • Crisafulli, C.1    Mazzon, E.2    Muia, C.3    Bella, P.4    Esposito, E.5    Meli, R.6    Cuzzocrea, S.7
  • 28
    • 1642576624 scopus 로고    scopus 로고
    • An intact NF-kappaB pathway is required for histone deacetylase inhibitor-induced G1 arrest and maturation in U937 human myeloid leukemia cells
    • Dai Y., Rahmani M., Grant S. An intact NF-kappaB pathway is required for histone deacetylase inhibitor-induced G1 arrest and maturation in U937 human myeloid leukemia cells. Cell Cycle 2003, 2:467-472.
    • (2003) Cell Cycle , vol.2 , pp. 467-472
    • Dai, Y.1    Rahmani, M.2    Grant, S.3
  • 29
    • 33745932460 scopus 로고    scopus 로고
    • Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding
    • Deng W.G., Tang S.T., Tseng H.P., Wu K.K. Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding. Blood 2006, 108:518-524.
    • (2006) Blood , vol.108 , pp. 518-524
    • Deng, W.G.1    Tang, S.T.2    Tseng, H.P.3    Wu, K.K.4
  • 30
    • 0038389797 scopus 로고    scopus 로고
    • Effects of melatonin on the expression of iNOS and COX-2 in rat models of colitis
    • Dong W.-G. Effects of melatonin on the expression of iNOS and COX-2 in rat models of colitis. World J. Gastroenterol. 2003, 9:1307-1311.
    • (2003) World J. Gastroenterol. , vol.9 , pp. 1307-1311
    • Dong, W.-G.1
  • 31
    • 54049093249 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: apoptotic effects and clinical implications (review)
    • Emanuele S., Lauricella M., Tesoriere G. Histone deacetylase inhibitors: apoptotic effects and clinical implications (review). Int. J. Oncol. 2008, 33:637-646.
    • (2008) Int. J. Oncol. , vol.33 , pp. 637-646
    • Emanuele, S.1    Lauricella, M.2    Tesoriere, G.3
  • 32
    • 80051667506 scopus 로고    scopus 로고
    • Protective effect of melatonin against human leukocyte apoptosis induced by intracellular calcium overload: relation with its antioxidant actions
    • Espino J., Bejarano I., Paredes S.D., Barriga C., Rodriguez A.B., Pariente J.A. Protective effect of melatonin against human leukocyte apoptosis induced by intracellular calcium overload: relation with its antioxidant actions. J. Pineal Res. 2011, 51:195-206.
    • (2011) J. Pineal Res. , vol.51 , pp. 195-206
    • Espino, J.1    Bejarano, I.2    Paredes, S.D.3    Barriga, C.4    Rodriguez, A.B.5    Pariente, J.A.6
  • 33
    • 49549087478 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 and metalloproteinase-2 activity and expression is reduced by melatonin during experimental colitis
    • Esposito E., Genovese T., Caminiti R., Bramonti P., Meli R., Cuzzocrea S. Matrix metalloproteinase-9 and metalloproteinase-2 activity and expression is reduced by melatonin during experimental colitis. J. Pineal Res. 2008, 45:166-173.
    • (2008) J. Pineal Res. , vol.45 , pp. 166-173
    • Esposito, E.1    Genovese, T.2    Caminiti, R.3    Bramonti, P.4    Meli, R.5    Cuzzocrea, S.6
  • 35
    • 79960148707 scopus 로고    scopus 로고
    • Timing is everything: the when and how of environmentally induced changes in the epigenome of animals
    • Faulk C., Dolinoy D.C. Timing is everything: the when and how of environmentally induced changes in the epigenome of animals. Epigenetics 2011, 6:791-797.
    • (2011) Epigenetics , vol.6 , pp. 791-797
    • Faulk, C.1    Dolinoy, D.C.2
  • 37
    • 9444236895 scopus 로고    scopus 로고
    • Minireview: cyclin D1: normal and abnormal functions
    • Fu M., Wang C., Li Z., Sakamaki T., Pestell R.G. Minireview: cyclin D1: normal and abnormal functions. Endocrinology 2004, 145:5439-5447.
    • (2004) Endocrinology , vol.145 , pp. 5439-5447
    • Fu, M.1    Wang, C.2    Li, Z.3    Sakamaki, T.4    Pestell, R.G.5
  • 38
    • 79960380554 scopus 로고    scopus 로고
    • Melatonin as a natural ally against oxidative stress: a physiochemical study
    • Galano A., Tan D.X., Reiter R.J. Melatonin as a natural ally against oxidative stress: a physiochemical study. J. Pineal Res. 2011, 51:1-16.
    • (2011) J. Pineal Res. , vol.51 , pp. 1-16
    • Galano, A.1    Tan, D.X.2    Reiter, R.J.3
  • 39
    • 67649957806 scopus 로고    scopus 로고
    • Induction of matrix metalloproteinase-9 and -3 in nonsteroidal anti-inflammatory drug-induced acute gastric ulcers in mice: regulation by melatonin
    • Ganguly K., Swarnakar S. Induction of matrix metalloproteinase-9 and -3 in nonsteroidal anti-inflammatory drug-induced acute gastric ulcers in mice: regulation by melatonin. J. Pineal Res. 2009, 47:43-55.
    • (2009) J. Pineal Res. , vol.47 , pp. 43-55
    • Ganguly, K.1    Swarnakar, S.2
  • 40
    • 33747594750 scopus 로고    scopus 로고
    • Hydrogen peroxide-mediated downregulation of matrix metalloprotease-2 in indomethacin-induced acute gastric ulceration is blocked by melatonin and other antioxidants
    • Ganguly K., Kundu P., Banerjee A., Reiter R.J., Swarnakar S. Hydrogen peroxide-mediated downregulation of matrix metalloprotease-2 in indomethacin-induced acute gastric ulceration is blocked by melatonin and other antioxidants. Free Radic. Biol. Med. 2006, 41:911-925.
    • (2006) Free Radic. Biol. Med. , vol.41 , pp. 911-925
    • Ganguly, K.1    Kundu, P.2    Banerjee, A.3    Reiter, R.J.4    Swarnakar, S.5
  • 42
    • 0032444559 scopus 로고    scopus 로고
    • Involvement of nuclear binding sites for melatonin in the regulation of IL-2 and IL-6 production by human blood mononuclear cells
    • Garcia-Maurino S., Gonzalez-Haba M.G., Calvo J.R., Goberna R., Guerrero J.M. Involvement of nuclear binding sites for melatonin in the regulation of IL-2 and IL-6 production by human blood mononuclear cells. J. Neuroimmunol. 1998, 92:76-84.
    • (1998) J. Neuroimmunol. , vol.92 , pp. 76-84
    • Garcia-Maurino, S.1    Gonzalez-Haba, M.G.2    Calvo, J.R.3    Goberna, R.4    Guerrero, J.M.5
  • 45
    • 33244482536 scopus 로고    scopus 로고
    • Combinatorial roles of nuclear receptors in inflammation and immunity
    • Glass C.K., Ogawa S. Combinatorial roles of nuclear receptors in inflammation and immunity. Nat. Rev. Immunol. 2006, 6:44-55.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 44-55
    • Glass, C.K.1    Ogawa, S.2
  • 48
    • 67649236122 scopus 로고    scopus 로고
    • Melatonin: signaling mechanisms of a pleiotropic agent
    • Hardeland R. Melatonin: signaling mechanisms of a pleiotropic agent. Biofactors 2009, 35:183-192.
    • (2009) Biofactors , vol.35 , pp. 183-192
    • Hardeland, R.1
  • 49
    • 79955783055 scopus 로고    scopus 로고
    • Melatonin and its metabolites as anti-nitrosating and anti-nitrating agents
    • Hardeland R. Melatonin and its metabolites as anti-nitrosating and anti-nitrating agents. J. Exp. Integr. Med. 2011, 1:67-81.
    • (2011) J. Exp. Integr. Med. , vol.1 , pp. 67-81
    • Hardeland, R.1
  • 50
    • 68249129060 scopus 로고    scopus 로고
    • Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines
    • Hardeland R., Tan D.X., Reiter R.J. Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines. J. Pineal Res. 2009, 47:109-126.
    • (2009) J. Pineal Res. , vol.47 , pp. 109-126
    • Hardeland, R.1    Tan, D.X.2    Reiter, R.J.3
  • 51
    • 0026775958 scopus 로고
    • Free radical theory of aging
    • Harman D. Free radical theory of aging. Mutat. Res. 1992, 275:257-266.
    • (1992) Mutat. Res. , vol.275 , pp. 257-266
    • Harman, D.1
  • 53
    • 77958130983 scopus 로고    scopus 로고
    • Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway
    • Hayes J.D. Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway. Antioxid. Redox Signal. 2010, 13:1713-1748.
    • (2010) Antioxid. Redox Signal. , vol.13 , pp. 1713-1748
    • Hayes, J.D.1
  • 54
    • 79960123768 scopus 로고    scopus 로고
    • Epigenetic mechanisms and cancer: an interface between the environment and the genome
    • Herceg Z., Vaissieve T. Epigenetic mechanisms and cancer: an interface between the environment and the genome. Epigenetics 2011, 6:804-819.
    • (2011) Epigenetics , vol.6 , pp. 804-819
    • Herceg, Z.1    Vaissieve, T.2
  • 56
    • 77955292644 scopus 로고    scopus 로고
    • RelB regulates manganese superoxide dismutase gene and resistance to ionizing radiation of prostate cancer cells
    • Holley A.K., Xu Y., St Clair D.K., St Clair W.H. RelB regulates manganese superoxide dismutase gene and resistance to ionizing radiation of prostate cancer cells. Ann. N. Y. Acad. Sci. 2010, 1201:129-136.
    • (2010) Ann. N. Y. Acad. Sci. , vol.1201 , pp. 129-136
    • Holley, A.K.1    Xu, Y.2    St Clair, D.K.3    St Clair, W.H.4
  • 58
    • 77956413585 scopus 로고    scopus 로고
    • Regulation of apoptosis-associated genes by histone deacetylase inhibitors: implications in cancer therapy
    • Jazirehi A.R. Regulation of apoptosis-associated genes by histone deacetylase inhibitors: implications in cancer therapy. Anticancer Drugs 2010, 21:805-813.
    • (2010) Anticancer Drugs , vol.21 , pp. 805-813
    • Jazirehi, A.R.1
  • 59
    • 67649970221 scopus 로고    scopus 로고
    • Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: therapeutic implications for prostate cancer
    • Joo S.S., Yoo Y.M. Melatonin induces apoptotic death in LNCaP cells via p38 and JNK pathways: therapeutic implications for prostate cancer. J. Pineal Res. 2009, 47:8-14.
    • (2009) J. Pineal Res. , vol.47 , pp. 8-14
    • Joo, S.S.1    Yoo, Y.M.2
  • 62
    • 68249112961 scopus 로고    scopus 로고
    • Melatonin downregulates nuclear erythroid 2-related factor 2 and nuclear factor-kappaB during prevention of oxidative liver injury in a dimethylnitrosamine model
    • Jung K.H., Hong S.W., Zheng H.M., Lee D.H., Hong S.S. Melatonin downregulates nuclear erythroid 2-related factor 2 and nuclear factor-kappaB during prevention of oxidative liver injury in a dimethylnitrosamine model. J. Pineal Res. 2009, 47:173-183.
    • (2009) J. Pineal Res. , vol.47 , pp. 173-183
    • Jung, K.H.1    Hong, S.W.2    Zheng, H.M.3    Lee, D.H.4    Hong, S.S.5
  • 63
    • 77749310344 scopus 로고    scopus 로고
    • Melatonin ameliorates cerulein-induced pancreatitis by the modulation of nuclear erythroid 2-related factor 2 and nuclear factor-kappaB in rats
    • Jung K.H., Hong S.W., Zheng H.M., Lee H.S., Lee H., Lee D.H., Lee S.Y., Hong S.S. Melatonin ameliorates cerulein-induced pancreatitis by the modulation of nuclear erythroid 2-related factor 2 and nuclear factor-kappaB in rats. J. Pineal Res. 2010, 48:239-250.
    • (2010) J. Pineal Res. , vol.48 , pp. 239-250
    • Jung, K.H.1    Hong, S.W.2    Zheng, H.M.3    Lee, H.S.4    Lee, H.5    Lee, D.H.6    Lee, S.Y.7    Hong, S.S.8
  • 64
    • 71549154751 scopus 로고    scopus 로고
    • Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer
    • Jung-Hynes B., Reiter R.J., Ahmad N. Sirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer. J. Pineal Res. 2010, 48:9-19.
    • (2010) J. Pineal Res. , vol.48 , pp. 9-19
    • Jung-Hynes, B.1    Reiter, R.J.2    Ahmad, N.3
  • 65
    • 79951632056 scopus 로고    scopus 로고
    • Melatonin, a novel Sirt1 inhibitor, imparts antiproliferative effects against prostate cancer in vitro in culture and in vivo in TRAMP model
    • Jung-Hynes B., Schmit T.L., Reagan-Shaw S.R., Siddiqui I.A., Mukhtar H., Ahmad N. Melatonin, a novel Sirt1 inhibitor, imparts antiproliferative effects against prostate cancer in vitro in culture and in vivo in TRAMP model. J. Pineal Res. 2011, 50:140-149.
    • (2011) J. Pineal Res. , vol.50 , pp. 140-149
    • Jung-Hynes, B.1    Schmit, T.L.2    Reagan-Shaw, S.R.3    Siddiqui, I.A.4    Mukhtar, H.5    Ahmad, N.6
  • 66
    • 13944252475 scopus 로고    scopus 로고
    • Transcription factor cross-talk: the estrogen receptor and KF-kappaB
    • Kalaitzidis D., Gilmore T.D. Transcription factor cross-talk: the estrogen receptor and KF-kappaB. Trends Endocrinol. Metab. 2005, 16:46-52.
    • (2005) Trends Endocrinol. Metab. , vol.16 , pp. 46-52
    • Kalaitzidis, D.1    Gilmore, T.D.2
  • 67
    • 79954419206 scopus 로고    scopus 로고
    • Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll-like receptor signaling pathway
    • Kang J.W., Koh E.J., Lee S.M. Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll-like receptor signaling pathway. J. Pineal Res. 2011, 50:403-411.
    • (2011) J. Pineal Res. , vol.50 , pp. 403-411
    • Kang, J.W.1    Koh, E.J.2    Lee, S.M.3
  • 68
    • 0032524357 scopus 로고    scopus 로고
    • New twists in gene regulation by glucocorticoid receptor: is DNA binding dispensable?
    • Karin M. New twists in gene regulation by glucocorticoid receptor: is DNA binding dispensable?. Cell 1998, 93:487-490.
    • (1998) Cell , vol.93 , pp. 487-490
    • Karin, M.1
  • 69
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • Karin M. Nuclear factor-kappaB in cancer development and progression. Nature 2006, 441:431-436.
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 70
    • 0034752461 scopus 로고    scopus 로고
    • Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription
    • Katoh Y., Itoh K., Yoshida E., Miyagishi M., Fukamizu A., Yamamoto M. Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription. Genes Cells 2001, 6:857-868.
    • (2001) Genes Cells , vol.6 , pp. 857-868
    • Katoh, Y.1    Itoh, K.2    Yoshida, E.3    Miyagishi, M.4    Fukamizu, A.5    Yamamoto, M.6
  • 71
    • 79953225194 scopus 로고    scopus 로고
    • Acetylation-deacetylation of the transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) regulates its transcriptional activity and nucleocytoplasmic localization
    • Kawai Y., Garduno L., Theodore M., Yang J., Arinze I.J. Acetylation-deacetylation of the transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) regulates its transcriptional activity and nucleocytoplasmic localization. J. Biol. Chem. 2011, 286:7629-7640.
    • (2011) J. Biol. Chem. , vol.286 , pp. 7629-7640
    • Kawai, Y.1    Garduno, L.2    Theodore, M.3    Yang, J.4    Arinze, I.J.5
  • 73
    • 85047677305 scopus 로고    scopus 로고
    • Nuclear factor kappaB-dependent mechanisms coordinate the synergistic effect of PMA and cytokines on the induction of superoxide dismutase 2
    • Kiningham K.K., Xu Y., Daosukho C., Popova B., St Clair D.K. Nuclear factor kappaB-dependent mechanisms coordinate the synergistic effect of PMA and cytokines on the induction of superoxide dismutase 2. Biochem. J. 2001, 353:147-156.
    • (2001) Biochem. J. , vol.353 , pp. 147-156
    • Kiningham, K.K.1    Xu, Y.2    Daosukho, C.3    Popova, B.4    St Clair, D.K.5
  • 75
    • 80054111599 scopus 로고    scopus 로고
    • Molecular, genetic and epigenetic pathways of peroxynitrite-induced cellular toxicity
    • Korkmaz A. Molecular, genetic and epigenetic pathways of peroxynitrite-induced cellular toxicity. Interdiscip. Toxicol. 2009, 2:219-228.
    • (2009) Interdiscip. Toxicol. , vol.2 , pp. 219-228
    • Korkmaz, A.1
  • 76
    • 84860336930 scopus 로고    scopus 로고
    • Reactive nitrogen species; devastating intracellular players and melatonin as a defender
    • Korkmaz A., Manchester L.C. Reactive nitrogen species; devastating intracellular players and melatonin as a defender. J. Exp. Integr. Med. 2011, 1:63-65.
    • (2011) J. Exp. Integr. Med. , vol.1 , pp. 63-65
    • Korkmaz, A.1    Manchester, L.C.2
  • 77
    • 36849090114 scopus 로고    scopus 로고
    • Epigenetic regulation: a new research area for melatonin?
    • Korkmaz A., Reiter R.J. Epigenetic regulation: a new research area for melatonin?. J. Pineal Res. 2008, 44:41-44.
    • (2008) J. Pineal Res. , vol.44 , pp. 41-44
    • Korkmaz, A.1    Reiter, R.J.2
  • 78
    • 0242608411 scopus 로고    scopus 로고
    • Involvement of nitric oxide and hyperbaric oxygen in the pathogenesis of cyclophosphamide induced hemorrhagic cystitis in rats
    • Korkmaz A., Oter S., Deveci S., Ozgurtas T., Topal T., Sadir S., Bilgic H. Involvement of nitric oxide and hyperbaric oxygen in the pathogenesis of cyclophosphamide induced hemorrhagic cystitis in rats. J. Urol. 2003, 170:2498-2502.
    • (2003) J. Urol. , vol.170 , pp. 2498-2502
    • Korkmaz, A.1    Oter, S.2    Deveci, S.3    Ozgurtas, T.4    Topal, T.5    Sadir, S.6    Bilgic, H.7
  • 79
    • 34250335972 scopus 로고    scopus 로고
    • Pathophysiological aspects of cyclophosphamide and ifosfamide induced hemorrhagic cystitis; implication of reactive oxygen and nitrogen species as well as PARP activation
    • Korkmaz A., Topal T., Oter S. Pathophysiological aspects of cyclophosphamide and ifosfamide induced hemorrhagic cystitis; implication of reactive oxygen and nitrogen species as well as PARP activation. Cell Biol. Toxicol. 2007, 23:303-312.
    • (2007) Cell Biol. Toxicol. , vol.23 , pp. 303-312
    • Korkmaz, A.1    Topal, T.2    Oter, S.3
  • 80
    • 55249099377 scopus 로고    scopus 로고
    • Hyperglycemia-related pathophysiologic mechanisms and potential beneficial actions of melatonin
    • Korkmaz A., Topal T., Oter S., Tan D.X., Reiter R.J. Hyperglycemia-related pathophysiologic mechanisms and potential beneficial actions of melatonin. Mini Rev. Med. Chem. 2008, 8:1144-1153.
    • (2008) Mini Rev. Med. Chem. , vol.8 , pp. 1144-1153
    • Korkmaz, A.1    Topal, T.2    Oter, S.3    Tan, D.X.4    Reiter, R.J.5
  • 82
    • 57149122743 scopus 로고    scopus 로고
    • Combination of melatonin and a peroxisome proliferator-activated receptor-gamma agonist induces apoptosis in a breast cancer cell line
    • Korkmaz A., Tamura H., Manchester L.C., Ogden G.B., Tan D.X., Reiter R.J. Combination of melatonin and a peroxisome proliferator-activated receptor-gamma agonist induces apoptosis in a breast cancer cell line. J. Pineal Res. 2009, 46:115-116.
    • (2009) J. Pineal Res. , vol.46 , pp. 115-116
    • Korkmaz, A.1    Tamura, H.2    Manchester, L.C.3    Ogden, G.B.4    Tan, D.X.5    Reiter, R.J.6
  • 84
    • 77649270763 scopus 로고    scopus 로고
    • Targeting NRF2 signaling for cancer chemoprevention
    • Kwak M.-K. Targeting NRF2 signaling for cancer chemoprevention. Toxicol. Appl. Pharmacol. 2010, 244:66-76.
    • (2010) Toxicol. Appl. Pharmacol. , vol.244 , pp. 66-76
    • Kwak, M.-K.1
  • 86
    • 59349102293 scopus 로고    scopus 로고
    • A novel interplay between membrane and nuclear melatonin receptors in human lymphocytes: significance in IL-2 production
    • Lardone P.J., Carrillo-Vico A., Molinero P., Rubio A., Guerrero J.M. A novel interplay between membrane and nuclear melatonin receptors in human lymphocytes: significance in IL-2 production. Cell Mol. Life Sci. 2009, 66:516-525.
    • (2009) Cell Mol. Life Sci. , vol.66 , pp. 516-525
    • Lardone, P.J.1    Carrillo-Vico, A.2    Molinero, P.3    Rubio, A.4    Guerrero, J.M.5
  • 88
    • 51449095189 scopus 로고    scopus 로고
    • Promising antitumor activity with MGCD0103, a novel isotype-selective histone deacetylase inhibitor
    • Le Tourneau C., Siu L.L. Promising antitumor activity with MGCD0103, a novel isotype-selective histone deacetylase inhibitor. Expert Opin. Investig. Drugs 2008, 17:1247-1254.
    • (2008) Expert Opin. Investig. Drugs , vol.17 , pp. 1247-1254
    • Le Tourneau, C.1    Siu, L.L.2
  • 90
    • 77956301403 scopus 로고    scopus 로고
    • Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1)
    • Leja-Szpak A., Jaworek J., Pierzchalski P., Reiter R.J. Melatonin induces pro-apoptotic signaling pathway in human pancreatic carcinoma cells (PANC-1). J. Pineal Res. 2010, 49:248-255.
    • (2010) J. Pineal Res. , vol.49 , pp. 248-255
    • Leja-Szpak, A.1    Jaworek, J.2    Pierzchalski, P.3    Reiter, R.J.4
  • 91
    • 59849113546 scopus 로고    scopus 로고
    • Molecular mechanisms of Nrf2-mediated antioxidant response
    • Li W., Kong A.N. Molecular mechanisms of Nrf2-mediated antioxidant response. Mol. Carcinog. 2009, 48:91-104.
    • (2009) Mol. Carcinog. , vol.48 , pp. 91-104
    • Li, W.1    Kong, A.N.2
  • 92
    • 25644449484 scopus 로고    scopus 로고
    • Melatonin reduces inflammatory injury through inhibiting NF-kappaB activation in rats with colitis
    • Li J.H., Yu J.P., Yu H.G., Xu X.M., Yu L.L., Liu J., Luo H.S. Melatonin reduces inflammatory injury through inhibiting NF-kappaB activation in rats with colitis. Mediators Inflamm. 2005, 2005:185-193.
    • (2005) Mediators Inflamm. , vol.2005 , pp. 185-193
    • Li, J.H.1    Yu, J.P.2    Yu, H.G.3    Xu, X.M.4    Yu, L.L.5    Liu, J.6    Luo, H.S.7
  • 93
    • 55949120110 scopus 로고    scopus 로고
    • Activation of Nrf2-antioxidant signaling attenuates NFkappaB-inflammatory response and elicits apoptosis
    • Li W., Khor T.O., Xu C., Shen G., Jeong W.S., Yu S., Kong A.N. Activation of Nrf2-antioxidant signaling attenuates NFkappaB-inflammatory response and elicits apoptosis. Biochem. Pharmacol. 2008, 76:1485-1489.
    • (2008) Biochem. Pharmacol. , vol.76 , pp. 1485-1489
    • Li, W.1    Khor, T.O.2    Xu, C.3    Shen, G.4    Jeong, W.S.5    Yu, S.6    Kong, A.N.7
  • 95
    • 0033005001 scopus 로고    scopus 로고
    • Protective effect of melatonin on injuried cerebral neurons is associated with bcl-2 protein over-expression
    • Ling X., Zhang L.M., Lu S.D., Li X.J., Sun F.Y. Protective effect of melatonin on injuried cerebral neurons is associated with bcl-2 protein over-expression. Zhongguo Yao Li Xue Bao 1999, 20:409-414.
    • (1999) Zhongguo Yao Li Xue Bao , vol.20 , pp. 409-414
    • Ling, X.1    Zhang, L.M.2    Lu, S.D.3    Li, X.J.4    Sun, F.Y.5
  • 96
    • 65049089113 scopus 로고    scopus 로고
    • Regulation of glutathione synthesis
    • Lu S.C. Regulation of glutathione synthesis. Mol. Aspects Med. 2009, 30:42-59.
    • (2009) Mol. Aspects Med. , vol.30 , pp. 42-59
    • Lu, S.C.1
  • 97
    • 62449189195 scopus 로고    scopus 로고
    • Melatonin reduces indomethacin-induced gastric mucosal cell apoptosis by preventing mitochondrial oxidative stress and the activation of mitochondrial pathway of apoptosis
    • Maity P., Bindu S., Dey S., Goyal M., Alam A., Pal C., Reiter R., Bandyopadhyay U. Melatonin reduces indomethacin-induced gastric mucosal cell apoptosis by preventing mitochondrial oxidative stress and the activation of mitochondrial pathway of apoptosis. J. Pineal Res. 2009, 46:314-323.
    • (2009) J. Pineal Res. , vol.46 , pp. 314-323
    • Maity, P.1    Bindu, S.2    Dey, S.3    Goyal, M.4    Alam, A.5    Pal, C.6    Reiter, R.7    Bandyopadhyay, U.8
  • 98
    • 0030002986 scopus 로고    scopus 로고
    • Progression of human breast cancers to the metastatic state is linked to hydroxyl radical-induced DNA damage
    • Malins D.C., Polissar N.L., Gunselman S.J. Progression of human breast cancers to the metastatic state is linked to hydroxyl radical-induced DNA damage. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:2557-2563.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 2557-2563
    • Malins, D.C.1    Polissar, N.L.2    Gunselman, S.J.3
  • 99
    • 34247880441 scopus 로고    scopus 로고
    • Development of histone deacetylase inhibitors for cancer treatment
    • Marchion D., Munster P. Development of histone deacetylase inhibitors for cancer treatment. Expert. Rev. Anticancer. Ther. 2007, 7:583-598.
    • (2007) Expert. Rev. Anticancer. Ther. , vol.7 , pp. 583-598
    • Marchion, D.1    Munster, P.2
  • 100
    • 77958574512 scopus 로고    scopus 로고
    • Plasticity and specificity of the circadian epigenome
    • Masri S., Sassone-Corsi P. Plasticity and specificity of the circadian epigenome. Nat. Neurosci. 2010, 13:1324-1329.
    • (2010) Nat. Neurosci. , vol.13 , pp. 1324-1329
    • Masri, S.1    Sassone-Corsi, P.2
  • 101
    • 77957333258 scopus 로고    scopus 로고
    • Induction of epigenetic alterations by dietary and other environmental factors
    • Mathers J.C. Induction of epigenetic alterations by dietary and other environmental factors. Adv. Genet. 2010, 71:3-39.
    • (2010) Adv. Genet. , vol.71 , pp. 3-39
    • Mathers, J.C.1
  • 102
    • 78650782788 scopus 로고    scopus 로고
    • Hepatoprotective actions of melatonin: possible mediation by melatonin receptors
    • Mathes A.M. Hepatoprotective actions of melatonin: possible mediation by melatonin receptors. World J. Gastroenterol. 2010, 16:6087-6097.
    • (2010) World J. Gastroenterol. , vol.16 , pp. 6087-6097
    • Mathes, A.M.1
  • 103
    • 0033979815 scopus 로고    scopus 로고
    • Roles of nuclear factor kappaB in neuronal survival and plasticity
    • Mattson M.P., Culmsee C., Yu Z., Camandola S. Roles of nuclear factor kappaB in neuronal survival and plasticity. J. Neurochem. 2000, 74:443-456.
    • (2000) J. Neurochem. , vol.74 , pp. 443-456
    • Mattson, M.P.1    Culmsee, C.2    Yu, Z.3    Camandola, S.4
  • 104
    • 22144498398 scopus 로고    scopus 로고
    • Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages
    • Mayo J.C., Sainz R.M., Tan D.X., Hardeland R., Leon J., Rodriguez C., Reiter R.J. Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages. J. Neuroimmunol. 2005, 165:139-149.
    • (2005) J. Neuroimmunol. , vol.165 , pp. 139-149
    • Mayo, J.C.1    Sainz, R.M.2    Tan, D.X.3    Hardeland, R.4    Leon, J.5    Rodriguez, C.6    Reiter, R.J.7
  • 108
    • 22944434894 scopus 로고    scopus 로고
    • Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors
    • Mollace V., Muscoli C., Masini E., Cuzzocrea S., Salvemini D. Modulation of prostaglandin biosynthesis by nitric oxide and nitric oxide donors. Pharmacol. Rev. 2005, 57:217-252.
    • (2005) Pharmacol. Rev. , vol.57 , pp. 217-252
    • Mollace, V.1    Muscoli, C.2    Masini, E.3    Cuzzocrea, S.4    Salvemini, D.5
  • 109
    • 78650894319 scopus 로고    scopus 로고
    • Crosstalk of reactive oxygen species and NF-kappaB signaling
    • Morgan M.J., Liu Z.G. Crosstalk of reactive oxygen species and NF-kappaB signaling. Cell Res. 2011, 21:103-115.
    • (2011) Cell Res. , vol.21 , pp. 103-115
    • Morgan, M.J.1    Liu, Z.G.2
  • 110
    • 0029553170 scopus 로고
    • The neurohormone melatonin inhibits cytokine, mitogen and ionizing radiation induced NF-kappa B
    • Natarajan M., Sadeghi K., Reiter R.J., Meltz M.L. The neurohormone melatonin inhibits cytokine, mitogen and ionizing radiation induced NF-kappa B. Biochem. Mol. Biol. Int. 1995, 37:1063-1070.
    • (1995) Biochem. Mol. Biol. Int. , vol.37 , pp. 1063-1070
    • Natarajan, M.1    Sadeghi, K.2    Reiter, R.J.3    Meltz, M.L.4
  • 111
    • 79951642115 scopus 로고    scopus 로고
    • Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF-kappaB and Nrf2 cascades
    • Negi G., Kumar A., Sharma S.S. Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF-kappaB and Nrf2 cascades. J. Pineal Res. 2011, 50:124-131.
    • (2011) J. Pineal Res. , vol.50 , pp. 124-131
    • Negi, G.1    Kumar, A.2    Sharma, S.S.3
  • 112
    • 3142711446 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase inhibition in cyclophosphamide induced hemorrhagic cystitis in rats
    • Oter S., Korkmaz A., Oztas E., Yildirim I., Topal T., Bilgic H. Inducible nitric oxide synthase inhibition in cyclophosphamide induced hemorrhagic cystitis in rats. Urol. Res. 2004, 32:185-189.
    • (2004) Urol. Res. , vol.32 , pp. 185-189
    • Oter, S.1    Korkmaz, A.2    Oztas, E.3    Yildirim, I.4    Topal, T.5    Bilgic, H.6
  • 113
    • 67650835195 scopus 로고    scopus 로고
    • Melatonin attenuates unilateral ureteral obstruction-induced renal injury by reducing oxidative stress, iNOS, MAPK, and NF-kB expression
    • Ozbek E., Ilbey Y.O., Ozbek M., Simsek A., Cekmen M., Somay A. Melatonin attenuates unilateral ureteral obstruction-induced renal injury by reducing oxidative stress, iNOS, MAPK, and NF-kB expression. J. Endourol. 2009, 23:1165-1173.
    • (2009) J. Endourol. , vol.23 , pp. 1165-1173
    • Ozbek, E.1    Ilbey, Y.O.2    Ozbek, M.3    Simsek, A.4    Cekmen, M.5    Somay, A.6
  • 114
    • 23944516082 scopus 로고    scopus 로고
    • Contribution of flavonoid antioxidants to the preventive effect of mesna in cyclophosphamide-induced cystitis in rats
    • Ozcan A., Korkmaz A., Oter S., Coskun O. Contribution of flavonoid antioxidants to the preventive effect of mesna in cyclophosphamide-induced cystitis in rats. Arch. Toxicol. 2005, 79:461-465.
    • (2005) Arch. Toxicol. , vol.79 , pp. 461-465
    • Ozcan, A.1    Korkmaz, A.2    Oter, S.3    Coskun, O.4
  • 116
    • 0031975809 scopus 로고    scopus 로고
    • Rhythms of glutathione peroxidase and glutathione reductase in the brain of chick and their inhibition by light
    • Pablos M.I., Reiter R.J., Ortiz G.G., Guerrero J.C., Agapito M.T., Chuang J.I. Rhythms of glutathione peroxidase and glutathione reductase in the brain of chick and their inhibition by light. Neurochem. Int. 1998, 32:69-75.
    • (1998) Neurochem. Int. , vol.32 , pp. 69-75
    • Pablos, M.I.1    Reiter, R.J.2    Ortiz, G.G.3    Guerrero, J.C.4    Agapito, M.T.5    Chuang, J.I.6
  • 117
    • 33748702268 scopus 로고    scopus 로고
    • Nuclear receptors versus inflammation: mechanisms of transrepression
    • Pascual G., Glass C.K. Nuclear receptors versus inflammation: mechanisms of transrepression. Trends Endocrinol. Metab. 2006, 17:321-327.
    • (2006) Trends Endocrinol. Metab. , vol.17 , pp. 321-327
    • Pascual, G.1    Glass, C.K.2
  • 119
    • 33845768987 scopus 로고    scopus 로고
    • Integrating cell-signalling pathways with NF-kappaB and IKK function
    • Perkins N.D. Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat. Rev. Mol. Cell Biol. 2007, 8:49-62.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 49-62
    • Perkins, N.D.1
  • 120
    • 33645971047 scopus 로고    scopus 로고
    • Good cop, bad cop: the different faces of NF-kappaB
    • Perkins N.D., Gilmore T.D. Good cop, bad cop: the different faces of NF-kappaB. Cell Death Differ. 2006, 13:759-772.
    • (2006) Cell Death Differ. , vol.13 , pp. 759-772
    • Perkins, N.D.1    Gilmore, T.D.2
  • 121
    • 0030614504 scopus 로고    scopus 로고
    • Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator
    • Perkins N.D., Felzien L.K., Betts J.C., Leung K., Beach D.H., Nabel G.J. Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science 1997, 275:523-527.
    • (1997) Science , vol.275 , pp. 523-527
    • Perkins, N.D.1    Felzien, L.K.2    Betts, J.C.3    Leung, K.4    Beach, D.H.5    Nabel, G.J.6
  • 122
    • 51649122293 scopus 로고    scopus 로고
    • Potential role of tryptophan derivatives in stress responses characterized by the generation of reactive oxygen and nitrogen species
    • Peyrot F., Ducrocq C. Potential role of tryptophan derivatives in stress responses characterized by the generation of reactive oxygen and nitrogen species. J. Pineal Res. 2008, 45:235-246.
    • (2008) J. Pineal Res. , vol.45 , pp. 235-246
    • Peyrot, F.1    Ducrocq, C.2
  • 124
    • 0033582431 scopus 로고    scopus 로고
    • Molecular mechanism of the regulation of glutathione synthesis by tumor necrosis factor-alpha and dexamethasone in human alveolar epithelial cells
    • Rahman I., Antonicelli F., MacNee W. Molecular mechanism of the regulation of glutathione synthesis by tumor necrosis factor-alpha and dexamethasone in human alveolar epithelial cells. J. Biol. Chem. 1999, 274:5088-5096.
    • (1999) J. Biol. Chem. , vol.274 , pp. 5088-5096
    • Rahman, I.1    Antonicelli, F.2    MacNee, W.3
  • 125
    • 0036066957 scopus 로고    scopus 로고
    • Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: potential mechanism in gene transcription in lung inflammation
    • Rahman I., Gilmour P.S., Jimenez L.A., MacNee W. Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: potential mechanism in gene transcription in lung inflammation. Mol. Cell. Biochem. 2002, 234-235:239-248.
    • (2002) Mol. Cell. Biochem. , pp. 239-248
    • Rahman, I.1    Gilmour, P.S.2    Jimenez, L.A.3    MacNee, W.4
  • 127
    • 0016311413 scopus 로고
    • Circannual reproductive rhythms in mammals related to photoperiod and pineal function: a review
    • Reiter R.J. Circannual reproductive rhythms in mammals related to photoperiod and pineal function: a review. Chronobiologia 1974, 1:365-395.
    • (1974) Chronobiologia , vol.1 , pp. 365-395
    • Reiter, R.J.1
  • 133
    • 68249122123 scopus 로고    scopus 로고
    • The circadian melatonin rhythm and its modulation: possible impact on hypertension
    • Reiter R.J., Tan D.X., Korkmaz A. The circadian melatonin rhythm and its modulation: possible impact on hypertension. J. Hypertens. 2009, (Suppl. 27):S17-S20.
    • (2009) J. Hypertens. , Issue.SUPPL. 27
    • Reiter, R.J.1    Tan, D.X.2    Korkmaz, A.3
  • 135
    • 79952287772 scopus 로고    scopus 로고
    • Circadian mechanisms in the regulation of melatonin synthesis: disruption with light at night and the pathophysiological consequences
    • Reiter R.J., Tan D.X., Sanchez-Barcelo E., Mediavilla M.D., Gitto E., Korkmaz A. Circadian mechanisms in the regulation of melatonin synthesis: disruption with light at night and the pathophysiological consequences. J. Exp. Integr. Med. 2011, 1:13-22.
    • (2011) J. Exp. Integr. Med. , vol.1 , pp. 13-22
    • Reiter, R.J.1    Tan, D.X.2    Sanchez-Barcelo, E.3    Mediavilla, M.D.4    Gitto, E.5    Korkmaz, A.6
  • 136
    • 84865627272 scopus 로고    scopus 로고
    • Obesity and metabolic syndrome: association with chronodisruption, sleep deprivation, and melatonin suppression
    • in press.
    • Reiter, R. J., Tan, D. X., Korkmaz, A., Ma, S., in press. Obesity and metabolic syndrome: association with chronodisruption, sleep deprivation, and melatonin suppression. Ann. Med.
    • Ann. Med.
    • Reiter, R.J.1    Tan, D.X.2    Korkmaz, A.3    Ma, S.4
  • 138
    • 33745714392 scopus 로고    scopus 로고
    • PPARs and other nuclear receptors in inflammation
    • Rizzo G., Fiorucci S. PPARs and other nuclear receptors in inflammation. Curr. Opin. Pharmacol. 2006, 6:421-427.
    • (2006) Curr. Opin. Pharmacol. , vol.6 , pp. 421-427
    • Rizzo, G.1    Fiorucci, S.2
  • 141
    • 34548760150 scopus 로고    scopus 로고
    • Alpha-tocopherol, beta-carotene and melatonin administration protects cyclophosphamide-induced oxidative damage to bladder tissue in rats
    • Sadir S., Deveci S., Korkmaz A., Oter S. Alpha-tocopherol, beta-carotene and melatonin administration protects cyclophosphamide-induced oxidative damage to bladder tissue in rats. Cell Biochem. Funct. 2007, 25:521-526.
    • (2007) Cell Biochem. Funct. , vol.25 , pp. 521-526
    • Sadir, S.1    Deveci, S.2    Korkmaz, A.3    Oter, S.4
  • 144
    • 51649128880 scopus 로고    scopus 로고
    • Epigenetic targets for melatonin: induction of histone H3 hyperacetylation and gene expression in C17.2 neural stem cells
    • Sharma R., Ottenhof T., Rzeczkowska P.A., Niles L.P. Epigenetic targets for melatonin: induction of histone H3 hyperacetylation and gene expression in C17.2 neural stem cells. J. Pineal Res. 2008, 45:277-284.
    • (2008) J. Pineal Res. , vol.45 , pp. 277-284
    • Sharma, R.1    Ottenhof, T.2    Rzeczkowska, P.A.3    Niles, L.P.4
  • 145
    • 0036603478 scopus 로고    scopus 로고
    • Melatonin and prostate cancer cell proliferation: interplay with castration, epidermal growth factor, and androgen sensitivity
    • Siu S.W., Lau K.W., Tam P.C., Shiu S.Y. Melatonin and prostate cancer cell proliferation: interplay with castration, epidermal growth factor, and androgen sensitivity. Prostate 2002, 52:106-122.
    • (2002) Prostate , vol.52 , pp. 106-122
    • Siu, S.W.1    Lau, K.W.2    Tam, P.C.3    Shiu, S.Y.4
  • 146
    • 0035221189 scopus 로고    scopus 로고
    • Nuclear melatonin receptors
    • Smirnov A.N. Nuclear melatonin receptors. Biochemistry (Mosc) 2001, 66:19-26.
    • (2001) Biochemistry (Mosc) , vol.66 , pp. 19-26
    • Smirnov, A.N.1
  • 147
    • 25144457115 scopus 로고    scopus 로고
    • Oxidative stress transiently decreases the IKK complex (IKKalpha, beta, and gamma), an upstream component of NF-kappaB signaling, after transient focal cerebral ischemia in mice
    • Song Y.S., Lee Y.S., Chan P.H. Oxidative stress transiently decreases the IKK complex (IKKalpha, beta, and gamma), an upstream component of NF-kappaB signaling, after transient focal cerebral ischemia in mice. J. Cereb. Blood Flow Metab. 2005, 25:1301-1311.
    • (2005) J. Cereb. Blood Flow Metab. , vol.25 , pp. 1301-1311
    • Song, Y.S.1    Lee, Y.S.2    Chan, P.H.3
  • 148
    • 33947518569 scopus 로고    scopus 로고
    • Reduced oxidative stress promotes NF-kappaB-mediated neuroprotective gene expression after transient focal cerebral ischemia: lymphocytotrophic cytokines and antiapoptotic factors
    • Song Y.S., Lee Y.S., Narasimhan P., Chan P.H. Reduced oxidative stress promotes NF-kappaB-mediated neuroprotective gene expression after transient focal cerebral ischemia: lymphocytotrophic cytokines and antiapoptotic factors. J. Cereb. Blood Flow Metab. 2007, 27:764-775.
    • (2007) J. Cereb. Blood Flow Metab. , vol.27 , pp. 764-775
    • Song, Y.S.1    Lee, Y.S.2    Narasimhan, P.3    Chan, P.H.4
  • 151
    • 0029760957 scopus 로고    scopus 로고
    • Redox regulation of transcriptional activators
    • Sun Y., Oberley L.W. Redox regulation of transcriptional activators. Free Radic. Biol. Med. 1996, 21:335-348.
    • (1996) Free Radic. Biol. Med. , vol.21 , pp. 335-348
    • Sun, Y.1    Oberley, L.W.2
  • 152
    • 66349129338 scopus 로고    scopus 로고
    • Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response
    • Sun Z., Chin Y.E., Zhang D.D. Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response. Mol. Cell. Biol. 2009, 29:2658-2672.
    • (2009) Mol. Cell. Biol. , vol.29 , pp. 2658-2672
    • Sun, Z.1    Chin, Y.E.2    Zhang, D.D.3
  • 153
    • 34447130377 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 activity and expression is reduced by melatonin during prevention of ethanol-induced gastric ulcer in mice
    • Swarnakar S., Mishra A., Ganguly K., Sharma A.V. Matrix metalloproteinase-9 activity and expression is reduced by melatonin during prevention of ethanol-induced gastric ulcer in mice. J. Pineal Res. 2007, 43:56-64.
    • (2007) J. Pineal Res. , vol.43 , pp. 56-64
    • Swarnakar, S.1    Mishra, A.2    Ganguly, K.3    Sharma, A.V.4
  • 154
    • 78650087766 scopus 로고    scopus 로고
    • Matrix metalloproteinases in health and disease: regulation by melatonin
    • Swarnakar S., Paul S., Jingh L.P., Reiter R.J. Matrix metalloproteinases in health and disease: regulation by melatonin. J. Pineal Res. 2011, 50:8-20.
    • (2011) J. Pineal Res. , vol.50 , pp. 8-20
    • Swarnakar, S.1    Paul, S.2    Jingh, L.P.3    Reiter, R.J.4
  • 157
    • 33845536018 scopus 로고    scopus 로고
    • One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species?
    • Tan D.X., Manchester L.C., Terron M.P., Flores L.J., Reiter R.J. One molecule, many derivatives: a never-ending interaction of melatonin with reactive oxygen and nitrogen species?. J. Pineal Res. 2007, 42:28-42.
    • (2007) J. Pineal Res. , vol.42 , pp. 28-42
    • Tan, D.X.1    Manchester, L.C.2    Terron, M.P.3    Flores, L.J.4    Reiter, R.J.5
  • 158
    • 79951838117 scopus 로고    scopus 로고
    • Significance and application of melatonin in the regulation of brown adipose tissue metabolism: relation to human obesity
    • Tan D.X., Manchester L.C., Fuentes-Broto I., Paredes S.D., Reiter R.J. Significance and application of melatonin in the regulation of brown adipose tissue metabolism: relation to human obesity. Obes. Rev. 2011, 12:167-188.
    • (2011) Obes. Rev. , vol.12 , pp. 167-188
    • Tan, D.X.1    Manchester, L.C.2    Fuentes-Broto, I.3    Paredes, S.D.4    Reiter, R.J.5
  • 159
    • 77950644583 scopus 로고    scopus 로고
    • Melatonin attenuates methamphetamine-induced overexpression of pro-inflammatory cytokines in microglial cell lines
    • Tocharus J., Khonthun C., Chongthammakun S., Govitrapong P. Melatonin attenuates methamphetamine-induced overexpression of pro-inflammatory cytokines in microglial cell lines. J. Pineal Res. 2010, 48:347-352.
    • (2010) J. Pineal Res. , vol.48 , pp. 347-352
    • Tocharus, J.1    Khonthun, C.2    Chongthammakun, S.3    Govitrapong, P.4
  • 160
    • 23744513206 scopus 로고    scopus 로고
    • A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes
    • Tomas-Zapico C., Coto-Montes A. A proposed mechanism to explain the stimulatory effect of melatonin on antioxidative enzymes. J. Pineal Res. 2005, 39:99-104.
    • (2005) J. Pineal Res. , vol.39 , pp. 99-104
    • Tomas-Zapico, C.1    Coto-Montes, A.2
  • 163
    • 77950648335 scopus 로고    scopus 로고
    • Effect of melatonin on the expression of Nrf2 and NF-kappaB during cyclophosphamide-induced urinary bladder injury in rat
    • Tripathi D.N., Jena G.B. Effect of melatonin on the expression of Nrf2 and NF-kappaB during cyclophosphamide-induced urinary bladder injury in rat. J. Pineal Res. 2010, 48:324-331.
    • (2010) J. Pineal Res. , vol.48 , pp. 324-331
    • Tripathi, D.N.1    Jena, G.B.2
  • 164
    • 34548397111 scopus 로고    scopus 로고
    • Melatonin alleviates lung damage induced by the chemical warfare agent nitrogen mustard
    • Ucar M., Korkmaz A., Reiter R.J., Yaren H., Oter S., Kurt B., Topal T. Melatonin alleviates lung damage induced by the chemical warfare agent nitrogen mustard. Toxicol. Lett. 2007, 173:124-131.
    • (2007) Toxicol. Lett. , vol.173 , pp. 124-131
    • Ucar, M.1    Korkmaz, A.2    Reiter, R.J.3    Yaren, H.4    Oter, S.5    Kurt, B.6    Topal, T.7
  • 165
    • 0032878234 scopus 로고    scopus 로고
    • Melatonin induces gamma-glutamylcysteine synthetase mediated by activator protein-1 in human vascular endothelial cells
    • Urata Y., Honma S., Goto S., Todoroki S., Iida T., Cho S., Honma K., Kondo T. Melatonin induces gamma-glutamylcysteine synthetase mediated by activator protein-1 in human vascular endothelial cells. Free Radic. Biol. Med. 1999, 27:838-847.
    • (1999) Free Radic. Biol. Med. , vol.27 , pp. 838-847
    • Urata, Y.1    Honma, S.2    Goto, S.3    Todoroki, S.4    Iida, T.5    Cho, S.6    Honma, K.7    Kondo, T.8
  • 166
    • 78649328799 scopus 로고    scopus 로고
    • Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling
    • Verdin E., Hirschey M.D., Finley L.W., Haigis M.C. Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling. Trends Biochem. Sci. 2010, 35:669-675.
    • (2010) Trends Biochem. Sci. , vol.35 , pp. 669-675
    • Verdin, E.1    Hirschey, M.D.2    Finley, L.W.3    Haigis, M.C.4
  • 167
    • 0037093071 scopus 로고    scopus 로고
    • Melatonin: from basic research to cancer treatment clinics
    • Vijayalaxmi, Thomas C.R., Reiter R.J., Herman T.S. Melatonin: from basic research to cancer treatment clinics. J. Clin. Oncol. 2002, 20:2575-2601.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 2575-2601
    • Vijayalaxmi1    Thomas, C.R.2    Reiter, R.J.3    Herman, T.S.4
  • 168
    • 70449339417 scopus 로고    scopus 로고
    • The antiapoptotic activity of melatonin in neurodegenerative diseases
    • Wang X. The antiapoptotic activity of melatonin in neurodegenerative diseases. CNS Neurosci. Ther. 2009, 15:345-357.
    • (2009) CNS Neurosci. Ther. , vol.15 , pp. 345-357
    • Wang, X.1
  • 169
    • 0036802356 scopus 로고    scopus 로고
    • The role of NF-kappaB in the regulation of cell stress responses
    • Wang T., Zhang X., Li J.J. The role of NF-kappaB in the regulation of cell stress responses. Int. Immunopharmacol. 2002, 2:1509-1520.
    • (2002) Int. Immunopharmacol. , vol.2 , pp. 1509-1520
    • Wang, T.1    Zhang, X.2    Li, J.J.3
  • 170
    • 0031847447 scopus 로고    scopus 로고
    • The potential role of the transcription factor RZR/ROR as a mediator of nuclear melatonin signaling
    • Wiesenberg I., Missbach M., Carlberg C. The potential role of the transcription factor RZR/ROR as a mediator of nuclear melatonin signaling. Restor. Neurol. Neurosci. 1998, 12:143-150.
    • (1998) Restor. Neurol. Neurosci. , vol.12 , pp. 143-150
    • Wiesenberg, I.1    Missbach, M.2    Carlberg, C.3
  • 173
    • 20344373696 scopus 로고    scopus 로고
    • NF-kappaB, an evolutionarily conserved mediator of immune and inflammatory responses
    • Xiao C., Ghosh S. NF-kappaB, an evolutionarily conserved mediator of immune and inflammatory responses. Adv. Exp. Med. Biol. 2005, 560:41-45.
    • (2005) Adv. Exp. Med. Biol. , vol.560 , pp. 41-45
    • Xiao, C.1    Ghosh, S.2
  • 174
    • 0032588841 scopus 로고    scopus 로고
    • An intronic NF-kappaB element is essential for induction of the human manganese superoxide dismutase gene by tumor necrosis factor-alpha and interleukin-1beta
    • Xu Y., Kiningham K.K., Devalaraja M.N., Yeh C.C., Majima H., Kasarskis E.J., St Clair D.K. An intronic NF-kappaB element is essential for induction of the human manganese superoxide dismutase gene by tumor necrosis factor-alpha and interleukin-1beta. DNA Cell Biol. 1999, 18:709-722.
    • (1999) DNA Cell Biol. , vol.18 , pp. 709-722
    • Xu, Y.1    Kiningham, K.K.2    Devalaraja, M.N.3    Yeh, C.C.4    Majima, H.5    Kasarskis, E.J.6    St Clair, D.K.7
  • 175
    • 7744243854 scopus 로고    scopus 로고
    • Contribution of antioxidants to preventive effect of mesna in cyclophosphamide-induced hemorrhagic cystitis in rats
    • Yildirim I., Korkmaz A., Oter S., Ozcan A., Oztas E. Contribution of antioxidants to preventive effect of mesna in cyclophosphamide-induced hemorrhagic cystitis in rats. Cancer Chemother. Pharmacol. 2004, 54:469-473.
    • (2004) Cancer Chemother. Pharmacol. , vol.54 , pp. 469-473
    • Yildirim, I.1    Korkmaz, A.2    Oter, S.3    Ozcan, A.4    Oztas, E.5
  • 176
    • 0035940984 scopus 로고    scopus 로고
    • Functional characterization of transcription regulators that interact with the electrophile response element
    • Zhu M., Fahl W.E. Functional characterization of transcription regulators that interact with the electrophile response element. Biochem. Biophys. Res. Commun. 2001, 289:212-219.
    • (2001) Biochem. Biophys. Res. Commun. , vol.289 , pp. 212-219
    • Zhu, M.1    Fahl, W.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.