Correction: SIRT2 regulates NF-κB-dependent gene expression through deacetylation of p65 Lys310 (Journal of Cell Science (2010) 123 (4251-4258) DOI: 10.1242/jcs.073783);SIRT2 regulates NF-κB-dependent gene expression through deacetylation of p65 Lys310

Journal of Cell Science

Volumn 123, Issue 24, 2010, Pages 4251-4258

  Rothgiesser, Karin M ^a   Erener, Süheda ^a   Waibel, Susanne ^b   Lüscher, Bernhard ^b   Hottiger, Michael O ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

Acetylation; K310; NF B; p65; RelA; SIRT2

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LYSINE; NICOTINAMIDE ADENINE DINUCLEOTIDE; SIRTUIN 1; SIRTUIN 2; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR P65; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ACETYLATION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOPLASM; DEACETYLATION; GENE CONTROL; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION;

EID: 78649738291     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.232801     Document Type: Erratum

References (40)

1. Beg, A. A. and Baltimore, D. (1996). An essential role for NF-kappaB in preventing TNF-alpha-induced cell death. Science 274, 782-784.
2. Black, J. C., Mosley, A., Kitada, T., Washburn, M. and Carey, M. (2008). The SIRT2 deacetylase regulates autoacetylation of p300. Mol. Cell 32, 449-455.
3. Bonizzi, G., Bebien, M., Otero, D. C., Johnson-Vroom, K. E., Cao, Y., Vu, D., Jegga, A. G., Aronow, B. J., Ghosh, G., Rickert, R. C. et al. (2004). Activation of IKKalpha target genes depends on recognition of specific kappaB binding sites by RelB:p52 dimers. EMBO J. 23, 4202-4210.
4. Buerki, C., Rothgiesser, K. M., Valovka, T., Owen, H. R., Rehrauer, H., Fey, M., Lane, W. S. and Hottiger, M. O. (2008). Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65. Nucleic Acids Res. 36, 1665-1680.
5. Chen, L., Fischle, W., Verdin, E. and Greene, W. C. (2001). Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science 293, 1653-1657.
6. Cheng, H. L., Mostoslavsky, R., Saito, S., Manis, J. P., Gu, Y., Patel, P., Bronson, R., Appella, E., Alt, F. W. and Chua, K. F. (2003). Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc. Natl. Acad. Sci. USA 100, 10794-10799.
7. Denu, J. M. (2003). Linking chromatin function with metabolic networks: Sir2 family of NAD(+)-dependent deacetylases. Trends Biochem. Sci. 28, 41-48.
8. Dryden, S. C., Nahhas, F. A., Nowak, J. E., Goustin, A. S. and Tainsky, M. A. (2003). Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle. Mol. Cell. Biol. 23, 3173-3185.
9. Ghosh, S., May, M. J. and Kopp, E. B. (1998). NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16, 225-260.
10. Hayden, M. S. and Ghosh, S. (2008). Shared principles in NF-kappaB signaling. Cell 132, 344-362.
11. Heltweg, B., Gatbonton, T., Schuler, A. D., Posakony, J., Li, H., Goehle, S., Kollipara, R., Depinho, R. A., Gu, Y., Simon, J. A. et al. (2006). Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes. Cancer Res. 66, 4368-4377.
12. Hoffmann, A. and Baltimore, D. (2006). Circuitry of nuclear factor kappaB signaling. Immunol. Rev. 210, 171-186.
13. Hoffmann, A., Levchenko, A., Scott, M. L. and Baltimore, D. (2002). The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation. Science 298, 1241-1245. (Pubitemid 35285493)
14. Huang, B., Yang, X., Zhou, M. M., Ozato, K. and Chen, L. F. (2008). Brd4 coactivates transcriptional activation of NF-{kappa}B via specific binding to acetylated RelA. Mol. Cell. Biol. 29, 1375-1387.
15. Huang, T. T., Kudo, N., Yoshida, M. and Miyamoto, S. (2000). A nuclear export signal in the N-terminal regulatory domain of IkappaBalpha controls cytoplasmic localization of inactive NF-kappaB/IkappaBalpha complexes. Proc. Natl. Acad. Sci. USA 97, 1014-1019.
16. Kawahara, T. L., Michishita, E., Adler, A. S., Damian, M., Berber, E., Lin, M., McCord, R. A., Ongaigui, K. C., Boxer, L. D., Chang, H. Y. et al. (2009). SIRT6 links histone H3 lysine 9 deacetylation to NF-kappaB-dependent gene expression and organismal life span. Cell 136, 62-74.
17. Kiernan, R., Bres, V., Ng, R. W., Coudart, M. P., El Messaoudi, S., Sardet, C., Jin, D. Y., Emiliani, S. and Benkirane, M. (2003). Post-activation turn-off of NF-kappa B-dependent transcription is regulated by acetylation of p65. J. Biol. Chem. 278, 2758-2766. (Pubitemid 36801357)
18. Michishita, E., Park, J. Y., Burneskis, J. M., Barrett, J. C. and Horikawa, I. (2005). Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins. Mol. Biol. Cell 16, 4623-4635. (Pubitemid 41416446)
19. Moreno, R., Sobotzik, J. M., Schultz, C. and Schmitz, M. L. (2010). Specification of the NF-{kappa}B transcriptional response by p65 phosphorylation and TNF-induced nuclear translocation of IKK{varepsilon}. Nucleic Acids Res. 38, 6029-6044.
20. North, B. J. and Verdin, E. (2007). Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis. PLoS ONE 2, e784.
21. North, B. J., Marshall, B. L., Borra, M. T., Denu, J. M. and Verdin, E. (2003). The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol. Cell 11, 437-444.
22. Oberdoerffer, P. and Sinclair, D. A. (2007). The role of nuclear architecture in genomic instability and ageing. Nat. Rev. Mol. Cell Biol. 8, 692-702.
23. Pahl, H. L. (1999). Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 18, 6853-6866.
24. Pandithage, R., Lilischkis, R., Harting, K., Wolf, A., Jedamzik, B., Luscher-Firzlaff, J., Vervoorts, J., Lasonder, E., Kremmer, E., Knoll, B. et al. (2008). The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility. J. Cell Biol. 180, 915-929. (Pubitemid 351398419)
25. Perez, P., Lira, S. A. and Bravo, R. (1995). Overexpression of RelA in transgenic mouse thymocytes: specific increase in levels of the inhibitor protein I kappa B alpha. Mol. Cell. Biol. 15, 3523-3530.
26. Perkins, N. D. (2006). Post-translational modifications regulating the activity and function of the nuclear factor kappa B pathway. Oncogene 25, 6717-6730.
27. Perkins, N. D., Felzien, L. K., Betts, J. C., Leung, K., Beach, D. H. and Nabel, G. J. (1997). Regulation of NF-kappaB by cyclin-dependent kinases associated with the p300 coactivator. Science 275, 523-527.
28. Perrod, S., Cockell, M. M., Laroche, T., Renauld, H., Ducrest, A. L., Bonnard, C. and Gasser, S. M. (2001). A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast. EMBO J. 20, 197-209.
29. Pfaffl, M. W., Horgan, G. W. and Dempfle, L. (2002). Relative expression software tool (REST) for group-wise comparison and statistical analysis of relative expression results in real-time PCR. Nucleic Acids Res. 30, e36.
30. Polager, S., Kalma, Y., Berkovich, E. and Ginsberg, D. (2002). E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis. Oncogene 21, 437-446. (Pubitemid 34123806)
31. Rothgiesser, K. M., Fey, M. and Hottiger, M. O. (2010). Acetylation of p65 at lysine 314 is important for late NF-kappaB-dependent gene expression. BMC Genomics 11, 22.
32. Sauve, A. A., Wolberger, C., Schramm, V. L. and Boeke, J. D. (2006). The biochemistry of sirtuins. Annu. Rev. Biochem. 75, 435-465.
33. Sterner, D. E. and Berger, S. L. (2000). Acetylation of histones and transcription-related factors. Microbiol. Mol. Biol. Rev. 64, 435-459.
34. Taylor, D. M., Maxwell, M. M., Luthi-Carter, R. and Kazantsev, A. G. (2008). Biological and potential therapeutic roles of sirtuin deacetylases. Cell. Mol. Life Sci. 65, 4000-4018.
35. Vaquero, A., Scher, M. B., Lee, D. H., Sutton, A., Cheng, H. L., Alt, F. W., Serrano, L., Sternglanz, R. and Reinberg, D. (2006). SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis. Genes Dev. 20, 1256-1261. (Pubitemid 43727586)
36. Westphal, C. H., Dipp, M. A. and Guarente, L. (2007). A therapeutic role for sirtuins in diseases of aging? Trends Biochem. Sci. 32, 555-560.
37. Yamamoto, H., Schoonjans, K. and Auwerx, J. (2007). Sirtuin functions in health and disease. Mol. Endocrinol. 21, 1745-1755.
38. Yang, X. J. and Seto, E. (2007). HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention. Oncogene 26, 5310-5318.
39. Yeung, F., Hoberg, J. E., Ramsey, C. S., Keller, M. D., Jones, D. R., Frye, R. A. and Mayo, M. W. (2004). Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J. 23, 2369-2380.
40. Zhong, H., May, M. J., Jimi, E. and Ghosh, S. (2002). The phosphorylation status of nuclear NF-kappa B determines its association with CBP/p300 or HDAC-1. Mol. Cell 9, 625-636.