-
1
-
-
68949206606
-
The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide
-
Albani D, Polito L, Batelli S, De Mauro S, Fracasso C, Martelli G, Colombo L, Manzoni C, Salmona M, Caccia S, Negro A, Forloni G. 2009. The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide. J Neurochem 110:1445-1456.
-
(2009)
J Neurochem
, vol.110
, pp. 1445-1456
-
-
Albani, D.1
Polito, L.2
Batelli, S.3
De Mauro, S.4
Fracasso, C.5
Martelli, G.6
Colombo, L.7
Manzoni, C.8
Salmona, M.9
Caccia, S.10
Negro, A.11
Forloni, G.12
-
2
-
-
75149192820
-
Sirtuins as novel targets for Alzheimer's disease and other neurodegenerative disorders: Experimental and genetic evidence
-
Albani D, Polito L, Forloni G. 2010. Sirtuins as novel targets for Alzheimer's disease and other neurodegenerative disorders: Experimental and genetic evidence. J Alzheimers Dis 19:11-26.
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 11-26
-
-
Albani, D.1
Polito, L.2
Forloni, G.3
-
3
-
-
34249669270
-
Sirt1 regulates aging and resistance to oxidative stress in the heart
-
Alcendor RR, Gao S, Zhai P, Zablocki D, Holle E, Yu X, Tian B, Wagner T, Vatner SF, Sadoshima J. 2007. Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res 100:1512-1521.
-
(2007)
Circ Res
, vol.100
, pp. 1512-1521
-
-
Alcendor, R.R.1
Gao, S.2
Zhai, P.3
Zablocki, D.4
Holle, E.5
Yu, X.6
Tian, B.7
Wagner, T.8
Vatner, S.F.9
Sadoshima, J.10
-
5
-
-
84878941111
-
Extranuclear localization of SIRT1 and PGC-1α: An insight into possible roles in diseases associated with mitochondrial dysfunction
-
Aquilano K, Baldelli S, Pagliei B, Ciriolo MR. 2012. Extranuclear localization of SIRT1 and PGC-1α: An insight into possible roles in diseases associated with mitochondrial dysfunction. Curr Mol Med 13:140-154.
-
(2012)
Curr Mol Med
, vol.13
, pp. 140-154
-
-
Aquilano, K.1
Baldelli, S.2
Pagliei, B.3
Ciriolo, M.R.4
-
6
-
-
74849124984
-
Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy
-
Armour SM, Baur JA, Hsieh SN, Land-Bracha A, Thomas SM, Sinclair DA. 2009. Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy. Aging 1:515-528.
-
(2009)
Aging
, vol.1
, pp. 515-528
-
-
Armour, S.M.1
Baur, J.A.2
Hsieh, S.N.3
Land-Bracha, A.4
Thomas, S.M.5
Sinclair, D.A.6
-
7
-
-
50249084987
-
Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum
-
Axe EL, Walker SA, Manifava M, Chandra P, Roderick HL, Habermann A, Griffiths G, Ktistakis NT. 2008. Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. J Cell Biol 182:685-701.
-
(2008)
J Cell Biol
, vol.182
, pp. 685-701
-
-
Axe, E.L.1
Walker, S.A.2
Manifava, M.3
Chandra, P.4
Roderick, H.L.5
Habermann, A.6
Griffiths, G.7
Ktistakis, N.T.8
-
8
-
-
78149471570
-
Autophagy in neurodegenerative disorders: Pathogenic roles and therapeutic implications
-
Banerjee R, Beal MF, Thomas B. 2010. Autophagy in neurodegenerative disorders: Pathogenic roles and therapeutic implications. Trends Neurosci 33:541-549.
-
(2010)
Trends Neurosci
, vol.33
, pp. 541-549
-
-
Banerjee, R.1
Beal, M.F.2
Thomas, B.3
-
9
-
-
0034872441
-
The c-Jun N-terminal protein kinase family of mitogen-activated protein kinases (JNK MAPKs)
-
Barr RK, Bogoyevitch MA. 2001. The c-Jun N-terminal protein kinase family of mitogen-activated protein kinases (JNK MAPKs). Int J Biochem Cell Biol 33:1047-1063.
-
(2001)
Int J Biochem Cell Biol
, vol.33
, pp. 1047-1063
-
-
Barr, R.K.1
Bogoyevitch, M.A.2
-
10
-
-
84861852370
-
Are sirtuins viable targets for improving healthspan and lifespan
-
Baur JA, Ungvari Z, Minor RK, Le Couteur DG, de Cabo R. 2012. Are sirtuins viable targets for improving healthspan and lifespan? Nat Rev Drug Discov 11:443-461.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 443-461
-
-
Baur, J.A.1
Ungvari, Z.2
Minor, R.K.3
Le Couteur, D.G.4
de Cabo, R.5
-
12
-
-
19944433088
-
A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages
-
Bellizzi D, Rose G, Cavalcante P, Covello G, Dato S, De Rango F, Greco V, Maggiolini M, Feraco E, Mari V, Franceschi C, Passarino G, De Benedictis G. 2005. A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages. Genomics 85:258-263.
-
(2005)
Genomics
, vol.85
, pp. 258-263
-
-
Bellizzi, D.1
Rose, G.2
Cavalcante, P.3
Covello, G.4
Dato, S.5
De Rango, F.6
Greco, V.7
Maggiolini, M.8
Feraco, E.9
Mari, V.10
Franceschi, C.11
Passarino, G.12
De Benedictis, G.13
-
13
-
-
62149114892
-
NAD(+), sirtuins, and cardiovascular disease
-
Borradaile NM, Pickering JG. 2009. NAD(+), sirtuins, and cardiovascular disease. Curr Pharm Des 15:110-117.
-
(2009)
Curr Pharm Des
, vol.15
, pp. 110-117
-
-
Borradaile, N.M.1
Pickering, J.G.2
-
14
-
-
80053168829
-
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
-
Burnett C. Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ, Vazquez-Manrique RP, Orfila AM, Ackerman D, Au C, Vinti G, Riesen M, Howard K, Neri C, Bedalov A, Kaeberlein M, Soti C, Partridge L, Gems D. 2011. Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature 477:482-485.
-
(2011)
Nature
, vol.477
, pp. 482-485
-
-
Burnett, C.1
Valentini, S.2
Cabreiro, F.3
Goss, M.4
Somogyvári, M.5
Piper, M.D.6
Hoddinott, M.7
Sutphin, G.L.8
Leko, V.9
McElwee, J.J.10
Vazquez-Manrique, R.P.11
Orfila, A.M.12
Ackerman, D.13
Au, C.14
Vinti, G.15
Riesen, M.16
Howard, K.17
Neri, C.18
Bedalov, A.19
Kaeberlein, M.20
Soti, C.21
Partridge, L.22
Gems, D.23
more..
-
15
-
-
69849107217
-
Caloric restriction, SIRT1 and longevity
-
Cantó C, Auwerx J. 2009. Caloric restriction, SIRT1 and longevity. Trends Endocrinol Metab 20:325-331.
-
(2009)
Trends Endocrinol Metab
, vol.20
, pp. 325-331
-
-
Cantó, C.1
Auwerx, J.2
-
16
-
-
64549127790
-
PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure
-
Cantó C, Auwerx J. 2009. PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure. Curr Opin Lipidol 20:98-105.
-
(2009)
Curr Opin Lipidol
, vol.20
, pp. 98-105
-
-
Cantó, C.1
Auwerx, J.2
-
17
-
-
39449108917
-
The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae
-
Cheong H, Nair U, Geng J, Klionsky DJ. 2008. The Atg1 kinase complex is involved in the regulation of protein recruitment to initiate sequestering vesicle formation for nonspecific autophagy in Saccharomyces cerevisiae. Mol Biol Cell 19:668-681.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 668-681
-
-
Cheong, H.1
Nair, U.2
Geng, J.3
Klionsky, D.J.4
-
18
-
-
72849130743
-
Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction
-
Cohen DE, Supinski AM, Bonkowski MS, Donmez G, Guarente LP. 2009. Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction. Genes Dev 23:2812-2817.
-
(2009)
Genes Dev
, vol.23
, pp. 2812-2817
-
-
Cohen, D.E.1
Supinski, A.M.2
Bonkowski, M.S.3
Donmez, G.4
Guarente, L.P.5
-
19
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
-
Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, Kessler B, Howitz KT, Gorospe M, de Cabo R, Sinclair DA. 2004. Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase. Science 305:390-392.
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
Howitz, K.T.7
Gorospe, M.8
de Cabo, R.9
Sinclair, D.A.10
-
20
-
-
79953773106
-
IKK-dependent, NF-κB-independent control of autophagic gene expression
-
Comb WC, Cogswell P, Sitcheran R, Baldwin AS. 2011. IKK-dependent, NF-κB-independent control of autophagic gene expression. Oncogene 30:1727-1732.
-
(2011)
Oncogene
, vol.30
, pp. 1727-1732
-
-
Comb, W.C.1
Cogswell, P.2
Sitcheran, R.3
Baldwin, A.S.4
-
21
-
-
75149129642
-
IKK connects autophagy to major stress pathways
-
Criollo A. Senovilla L, Authier H, Maiuri MC, Morselli E, Vitale I, Kepp O, Tasdemir E, Galluzzi L, Shen S, Tailler M, Delahaye N, Tesniere A, De Stefano D, Younes AB, Harper F, Pierron G, Lavandero S, Zitvogel L, Israel A, Baud V, Kroemer G. 2010. IKK connects autophagy to major stress pathways. Autophagy 6:189-191.
-
(2010)
Autophagy
, vol.6
, pp. 189-191
-
-
Criollo, A.1
Senovilla, L.2
Authier, H.3
Maiuri, M.C.4
Morselli, E.5
Vitale, I.6
Kepp, O.7
Tasdemir, E.8
Galluzzi, L.9
Shen, S.10
Tailler, M.11
Delahaye, N.12
Tesniere, A.13
De Stefano, D.14
Younes, A.B.15
Harper, F.16
Pierron, G.17
Lavandero, S.18
Zitvogel, L.19
Israel, A.20
Baud, V.21
Kroemer, G.22
more..
-
22
-
-
76349090912
-
The IKK complex contributes to the induction of autophagy
-
Criollo A, Senovilla L, Authier H, Maiuri MC, Morselli E, Vitale I, Kepp O, Tasdemir E, Galluzzi L, Shen S, Tailler M, Delahaye N, Tesniere A, De Stefano D, Younes AB, Harper F, Pierron G, Lavandero S, Zitvogel L, Israel A, Baud V, Kroemer G. 2010. The IKK complex contributes to the induction of autophagy. EMBO J 29:619-631.
-
(2010)
EMBO J
, vol.29
, pp. 619-631
-
-
Criollo, A.1
Senovilla, L.2
Authier, H.3
Maiuri, M.C.4
Morselli, E.5
Vitale, I.6
Kepp, O.7
Tasdemir, E.8
Galluzzi, L.9
Shen, S.10
Tailler, M.11
Delahaye, N.12
Tesniere, A.13
De Stefano, D.14
Younes, A.B.15
Harper, F.16
Pierron, G.17
Lavandero, S.18
Zitvogel, L.19
Israel, A.20
Baud, V.21
Kroemer, G.22
more..
-
23
-
-
33746326449
-
Augmentation of oridonin-induced apoptosis observed with reduced autophagy
-
Cui Q, Tashiro SI, Onodera S, Ikejima T. 2006. Augmentation of oridonin-induced apoptosis observed with reduced autophagy. J Pharmacol Sci 101:230-239.
-
(2006)
J Pharmacol Sci
, vol.101
, pp. 230-239
-
-
Cui, Q.1
Tashiro, S.I.2
Onodera, S.3
Ikejima, T.4
-
24
-
-
80052968080
-
Regulation of FoxO transcription factors by acetylation and protein-protein interactions
-
Daitoku H, Sakamaki JI, Fukamizu A. 2011. Regulation of FoxO transcription factors by acetylation and protein-protein interactions. Biochim Biophys Acta 1813:1954-1960.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 1954-1960
-
-
Daitoku, H.1
Sakamaki, J.I.2
Fukamizu, A.3
-
25
-
-
77949552845
-
Resveratrol attenuates renal hypertrophy in early-stage diabetes by activating AMPK
-
Ding DF, You N, Wu XM, Xu JR, Hu AP, Ye XL, Zhu Q, Jiang XQ, Miao H, Liu C, Lu YB. 2010. Resveratrol attenuates renal hypertrophy in early-stage diabetes by activating AMPK. Am J Nephrol 31:363-374.
-
(2010)
Am J Nephrol
, vol.31
, pp. 363-374
-
-
Ding, D.F.1
You, N.2
Wu, X.M.3
Xu, J.R.4
Hu, A.P.5
Ye, X.L.6
Zhu, Q.7
Jiang, X.Q.8
Miao, H.9
Liu, C.10
Lu, Y.B.11
-
26
-
-
79959956124
-
Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism
-
Donadelli M, Dando I, Zaniboni T, Costanzo C, Dalla Pozza E, Scupoli MT, Scarpa A, Zappavigna S, Marra M, Abbruzzese A, Bifulco M, Caraglia M, Palmieri M. 2011. Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism. Cell Death Dis 2:e152.
-
(2011)
Cell Death Dis
, vol.2
-
-
Donadelli, M.1
Dando, I.2
Zaniboni, T.3
Costanzo, C.4
Dalla Pozza, E.5
Scupoli, M.T.6
Scarpa, A.7
Zappavigna, S.8
Marra, M.9
Abbruzzese, A.10
Bifulco, M.11
Caraglia, M.12
Palmieri, M.13
-
27
-
-
84855929223
-
SIRT1 protects against α-synuclein aggregation by activating molecular chaperones
-
Donmez G, Arun A, Chung CY, McLean PJ, Lindquist S, Guarente L. 2012. SIRT1 protects against α-synuclein aggregation by activating molecular chaperones. J Neurosci 32:124-132.
-
(2012)
J Neurosci
, vol.32
, pp. 124-132
-
-
Donmez, G.1
Arun, A.2
Chung, C.Y.3
McLean, P.J.4
Lindquist, S.5
Guarente, L.6
-
28
-
-
77953257025
-
Aging and disease: Connections to sirtuins
-
Donmez G, Guarente L. 2010. Aging and disease: Connections to sirtuins. Aging Cell 9:285-290.
-
(2010)
Aging Cell
, vol.9
, pp. 285-290
-
-
Donmez, G.1
Guarente, L.2
-
29
-
-
77955046461
-
SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10
-
Donmez G, Wang D, Cohen DE, Guarente L. 2010. SIRT1 suppresses beta-amyloid production by activating the alpha-secretase gene ADAM10. Cell 142:320-332.
-
(2010)
Cell
, vol.142
, pp. 320-332
-
-
Donmez, G.1
Wang, D.2
Cohen, D.E.3
Guarente, L.4
-
30
-
-
57649195400
-
Autophagy and multivesicular bodies: Two closely related partners
-
Fader CM, Colombo MI. 2009. Autophagy and multivesicular bodies: Two closely related partners. Cell Death Differ 16:70-78.
-
(2009)
Cell Death Differ
, vol.16
, pp. 70-78
-
-
Fader, C.M.1
Colombo, M.I.2
-
31
-
-
53649100104
-
JNK2-dependent regulation of SIRT1 protein stability
-
Ford J, Ahmed S, Allison S, Jiang M, Milner J. 2008. JNK2-dependent regulation of SIRT1 protein stability. Cell Cycle 7:3091-3097.
-
(2008)
Cell Cycle
, vol.7
, pp. 3091-3097
-
-
Ford, J.1
Ahmed, S.2
Allison, S.3
Jiang, M.4
Milner, J.5
-
32
-
-
43949143804
-
The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy
-
Fujita N, Itoh T, Omori H, Fukuda M, Noda T, Yoshimori T. 2008. The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell 19:2092-2100.
-
(2008)
Mol Biol Cell
, vol.19
, pp. 2092-2100
-
-
Fujita, N.1
Itoh, T.2
Omori, H.3
Fukuda, M.4
Noda, T.5
Yoshimori, T.6
-
33
-
-
79959355078
-
Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity
-
Gao Z, Zhang J, Kheterpal I, Kennedy N, Davis RJ, Ye J. 2011. Sirtuin 1 (SIRT1) protein degradation in response to persistent c-Jun N-terminal kinase 1 (JNK1) activation contributes to hepatic steatosis in obesity. J Biol Chem 286:22227-22234.
-
(2011)
J Biol Chem
, vol.286
, pp. 22227-22234
-
-
Gao, Z.1
Zhang, J.2
Kheterpal, I.3
Kennedy, N.4
Davis, R.J.5
Ye, J.6
-
34
-
-
77950127881
-
SIRT1 negatively regulates the mammalian target of rapamycin
-
Ghosh HS, McBurney M, Robbins PD. 2010. SIRT1 negatively regulates the mammalian target of rapamycin. PLoS ONE 5:e9199.
-
(2010)
PLoS ONE
, vol.5
-
-
Ghosh, H.S.1
McBurney, M.2
Robbins, P.D.3
-
35
-
-
84860809347
-
SIRT3, a pivotal actor in mitochondrial functions: Metabolism, cell death and aging
-
Giralt A, Villarroya F. 2012. SIRT3, a pivotal actor in mitochondrial functions: Metabolism, cell death and aging. Biochem J 444:1-10.
-
(2012)
Biochem J
, vol.444
, pp. 1-10
-
-
Giralt, A.1
Villarroya, F.2
-
36
-
-
77951915586
-
Autophagy during cardiac stress: Joys and frustrations of autophagy
-
Gottlieb RA, Mentzer RM. 2010. Autophagy during cardiac stress: Joys and frustrations of autophagy. Annu Rev Physiol 72:45-59.
-
(2010)
Annu Rev Physiol
, vol.72
, pp. 45-59
-
-
Gottlieb, R.A.1
Mentzer, R.M.2
-
38
-
-
77949887506
-
Mammalian sirtuins: Biological insights and disease relevance
-
Haigis MC, Sinclair DA. 2010. Mammalian sirtuins: Biological insights and disease relevance. Annu Rev Pathol 5:253-295.
-
(2010)
Annu Rev Pathol
, vol.5
, pp. 253-295
-
-
Haigis, M.C.1
Sinclair, D.A.2
-
39
-
-
84875365804
-
Autophagosomes form at ER-mitochondria contact sites
-
Hamasaki M, Furuta N, Matsuda A, Nezu A, Yamamoto A, Fujita N, Oomori H, Noda T, Haraguchi T, Hiraoka Y, Amano A, Yoshimori T. 2013. Autophagosomes form at ER-mitochondria contact sites. Nature 495:389-393.
-
(2013)
Nature
, vol.495
, pp. 389-393
-
-
Hamasaki, M.1
Furuta, N.2
Matsuda, A.3
Nezu, A.4
Yamamoto, A.5
Fujita, N.6
Oomori, H.7
Noda, T.8
Haraguchi, T.9
Hiraoka, Y.10
Amano, A.11
Yoshimori, T.12
-
40
-
-
77950462712
-
Where do they come from? Insights into autophagosome formation
-
Hamasaki M, Yoshimori T. 2010. Where do they come from? Insights into autophagosome formation. FEBS Lett 584:1296-1301.
-
(2010)
FEBS Lett
, vol.584
, pp. 1296-1301
-
-
Hamasaki, M.1
Yoshimori, T.2
-
41
-
-
39749087530
-
SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization
-
Han MK, Song EK, Guo Y, Ou X, Mantel C, Broxmeyer HE. 2008. SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization. Cell Stem Cell 2:241-251.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 241-251
-
-
Han, M.K.1
Song, E.K.2
Guo, Y.3
Ou, X.4
Mantel, C.5
Broxmeyer, H.E.6
-
42
-
-
77957883314
-
Sirtuins and their relevance to the kidney
-
Hao CM, Haase VH. 2010. Sirtuins and their relevance to the kidney. J Am Soc Nephrol 21:1620-1627.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1620-1627
-
-
Hao, C.M.1
Haase, V.H.2
-
43
-
-
78650691023
-
Deacetylation of FoxO by Sirt1 plays an essential role in mediating starvation-induced autophagy in cardiac myocytes
-
Hariharan N, Maejima Y, Nakae J, Paik J, Depinho RA, Sadoshima J. 2010. Deacetylation of FoxO by Sirt1 plays an essential role in mediating starvation-induced autophagy in cardiac myocytes. Circ Res 107:1470-1482.
-
(2010)
Circ Res
, vol.107
, pp. 1470-1482
-
-
Hariharan, N.1
Maejima, Y.2
Nakae, J.3
Paik, J.4
Depinho, R.A.5
Sadoshima, J.6
-
44
-
-
78650758398
-
Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
-
Herranz D, Muñoz-Martin M, Cañamero M, Mulero F, Martinez-Pastor B, Fernandez-Capetillo O, Serrano M. 2010. Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer. Nat Commun 1:1-8.
-
(2010)
Nat Commun
, vol.1
, pp. 1-8
-
-
Herranz, D.1
Muñoz-Martin, M.2
Cañamero, M.3
Mulero, F.4
Martinez-Pastor, B.5
Fernandez-Capetillo, O.6
Serrano, M.7
-
45
-
-
84856111924
-
The unfolded protein response: Controlling cell fate decisions under ER stress and beyond
-
Hetz C. 2012. The unfolded protein response: Controlling cell fate decisions under ER stress and beyond. Nat Rev Mol Cell Biol 13:89-102.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 89-102
-
-
Hetz, C.1
-
47
-
-
73449133720
-
Nicotinamide phosphoribosyltransferase regulates cell survival through autophagy in cardiomyocytes
-
Hsu CP, Hariharan N, Alcendor RR, Oka S, Sadoshima J. 2009. Nicotinamide phosphoribosyltransferase regulates cell survival through autophagy in cardiomyocytes. Autophagy 5:1229-1231.
-
(2009)
Autophagy
, vol.5
, pp. 1229-1231
-
-
Hsu, C.P.1
Hariharan, N.2
Alcendor, R.R.3
Oka, S.4
Sadoshima, J.5
-
49
-
-
70149095672
-
Nicotinamide phosphoribosyltransferase regulates cell survival through NAD+ synthesis in cardiac myocytes
-
Hsu CP, Oka S, Shao D, Hariharan N, Sadoshima J. 2009. Nicotinamide phosphoribosyltransferase regulates cell survival through NAD+ synthesis in cardiac myocytes. Circ Res 105:481-491.
-
(2009)
Circ Res
, vol.105
, pp. 481-491
-
-
Hsu, C.P.1
Oka, S.2
Shao, D.3
Hariharan, N.4
Sadoshima, J.5
-
50
-
-
79959343572
-
The controversial links among calorie restriction, SIRT1, and resveratrol
-
Hu Y, Liu J, Wang J, Liu Q. 2011. The controversial links among calorie restriction, SIRT1, and resveratrol. Free Radic Biol Med 51:250-256.
-
(2011)
Free Radic Biol Med
, vol.51
, pp. 250-256
-
-
Hu, Y.1
Liu, J.2
Wang, J.3
Liu, Q.4
-
51
-
-
34548289502
-
Dynamic FoxO transcription factors
-
Huang H, Tindall DJ. 2007. Dynamic FoxO transcription factors. J Cell Sci 120:2479-2487.
-
(2007)
J Cell Sci
, vol.120
, pp. 2479-2487
-
-
Huang, H.1
Tindall, D.J.2
-
52
-
-
66349120877
-
Autophagy protects neuron from Abeta-induced cytotoxicity
-
Hung SY, Huang WP, Liou HC, Fu WM. 2009. Autophagy protects neuron from Abeta-induced cytotoxicity. Autophagy 5:502-510.
-
(2009)
Autophagy
, vol.5
, pp. 502-510
-
-
Hung, S.Y.1
Huang, W.P.2
Liou, H.C.3
Fu, W.M.4
-
53
-
-
77954623119
-
Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: Implication in pathogenesis of COPD
-
Hwang JW, Chung S, Sundar IK, Yao H, Arunachalam G, McBurney MW, Rahman I. 2010. Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: Implication in pathogenesis of COPD. Arch Biochem Biophys 500:203-209.
-
(2010)
Arch Biochem Biophys
, vol.500
, pp. 203-209
-
-
Hwang, J.W.1
Chung, S.2
Sundar, I.K.3
Yao, H.4
Arunachalam, G.5
McBurney, M.W.6
Rahman, I.7
-
54
-
-
34248151365
-
The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation
-
Inoue T, Hiratsuka M, Osaki M, Oshimura M. 2007. The molecular biology of mammalian SIRT proteins: SIRT2 in cell cycle regulation. Cell Cycle 6:1011-1018.
-
(2007)
Cell Cycle
, vol.6
, pp. 1011-1018
-
-
Inoue, T.1
Hiratsuka, M.2
Osaki, M.3
Oshimura, M.4
-
55
-
-
77955884684
-
Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins
-
Itakura E, Mizushima N. 2010. Characterization of autophagosome formation site by a hierarchical analysis of mammalian Atg proteins. Autophagy 6:764-776.
-
(2010)
Autophagy
, vol.6
, pp. 764-776
-
-
Itakura, E.1
Mizushima, N.2
-
56
-
-
84861722850
-
Nicotinamide-induced mitophagy: Event mediated by high NAD+/NADH ratio and SIRT1 protein activation
-
Jang SY, Kang HT, Hwang ES. 2012. Nicotinamide-induced mitophagy: Event mediated by high NAD+/NADH ratio and SIRT1 protein activation. J Biol Chem 287:19304-19314.
-
(2012)
J Biol Chem
, vol.287
, pp. 19304-19314
-
-
Jang, S.Y.1
Kang, H.T.2
Hwang, E.S.3
-
57
-
-
84855563516
-
Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway
-
Jeong H, Cohen DE, Cui L, Supinski A, Savas JN, Mazzulli JR, Yates JR, Bordone L, Guarente L, Krainc D. 2011. Sirt1 mediates neuroprotection from mutant huntingtin by activation of the TORC1 and CREB transcriptional pathway. Nat Med 18:159-165.
-
(2011)
Nat Med
, vol.18
, pp. 159-165
-
-
Jeong, H.1
Cohen, D.E.2
Cui, L.3
Supinski, A.4
Savas, J.N.5
Mazzulli, J.R.6
Yates, J.R.7
Bordone, L.8
Guarente, L.9
Krainc, D.10
-
58
-
-
84868139191
-
Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity
-
Jeong JK, Moon MH, Lee YJ, Seol JW, Park SY. 2012. Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity. Neurobiol Aging 34:146-156.
-
(2012)
Neurobiol Aging
, vol.34
, pp. 146-156
-
-
Jeong, J.K.1
Moon, M.H.2
Lee, Y.J.3
Seol, J.W.4
Park, S.Y.5
-
59
-
-
84863981612
-
Emerging roles of SIRT6 on telomere maintenance, DNA repair, metabolism and mammalian aging
-
Jia G, Su L, Singhal S, Liu X. 2012. Emerging roles of SIRT6 on telomere maintenance, DNA repair, metabolism and mammalian aging. Mol Cell Biochem 364:345-350.
-
(2012)
Mol Cell Biochem
, vol.364
, pp. 345-350
-
-
Jia, G.1
Su, L.2
Singhal, S.3
Liu, X.4
-
60
-
-
84855544817
-
Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets
-
Jiang M., et al. 2011. Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets. Nat Med 18:153-158.
-
(2011)
Nat Med
, vol.18
, pp. 153-158
-
-
Jiang, M.1
-
62
-
-
33947715833
-
p53, Autophagy and tumor suppression
-
Jin S. 2005. p53, Autophagy and tumor suppression. Autophagy 1:171-173.
-
(2005)
Autophagy
, vol.1
, pp. 171-173
-
-
Jin, S.1
-
63
-
-
34347354447
-
Sir2 and calorie restriction in yeast: A skeptical perspective
-
Kaeberlein M, Powers RW. 2007. Sir2 and calorie restriction in yeast: A skeptical perspective. Ageing Res Rev 6:128-140.
-
(2007)
Ageing Res Rev
, vol.6
, pp. 128-140
-
-
Kaeberlein, M.1
Powers, R.W.2
-
64
-
-
84858000209
-
The sirtuin SIRT6 regulates lifespan in male mice
-
Kanfi Y, Naiman S, Amir G, Peshti V, Zinman G, Nahum L, Bar-Joseph Z, Cohen HY. 2012. The sirtuin SIRT6 regulates lifespan in male mice. Nature 483:218-221.
-
(2012)
Nature
, vol.483
, pp. 218-221
-
-
Kanfi, Y.1
Naiman, S.2
Amir, G.3
Peshti, V.4
Zinman, G.5
Nahum, L.6
Bar-Joseph, Z.7
Cohen, H.Y.8
-
65
-
-
80055108043
-
Constitutive SIRT1 overexpression impairs mitochondria and reduces cardiac function in mice
-
Kawashima T, Inuzuka Y, Okuda J, Kato T, Niizuma S, Tamaki Y, Iwanaga Y, Kawamoto A, Narazaki M, Matsuda T, Adachi S, Takemura G, Kita T, Kimura T, Shioi T. 2011. Constitutive SIRT1 overexpression impairs mitochondria and reduces cardiac function in mice. J Mol Cell Cardiol 51:1026-1036.
-
(2011)
J Mol Cell Cardiol
, vol.51
, pp. 1026-1036
-
-
Kawashima, T.1
Inuzuka, Y.2
Okuda, J.3
Kato, T.4
Niizuma, S.5
Tamaki, Y.6
Iwanaga, Y.7
Kawamoto, A.8
Narazaki, M.9
Matsuda, T.10
Adachi, S.11
Takemura, G.12
Kita, T.13
Kimura, T.14
Shioi, T.15
-
66
-
-
79952353862
-
Neuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture
-
Kim SH, Lu HF, Alano CC. 2011. Neuronal Sirt3 protects against excitotoxic injury in mouse cortical neuron culture. PLoS ONE 6:e14731.
-
(2011)
PLoS ONE
, vol.6
-
-
Kim, S.H.1
Lu, H.F.2
Alano, C.C.3
-
67
-
-
81555225308
-
Dietary restriction ameliorates diabetic nephropathy through anti-inflammatory effects and regulation of the autophagy via restoration of Sirt1 in diabetic Wistar fatty (fa/fa) rats: A model of type 2 diabetes
-
Kitada M, Takeda A, Nagai T, Ito H, Kanasaki K, Koya D. 2011. Dietary restriction ameliorates diabetic nephropathy through anti-inflammatory effects and regulation of the autophagy via restoration of Sirt1 in diabetic Wistar fatty (fa/fa) rats: A model of type 2 diabetes. Exp Diabetes Res 2011:908185.
-
(2011)
Exp Diabetes Res
, vol.2011
, pp. 908185
-
-
Kitada, M.1
Takeda, A.2
Nagai, T.3
Ito, H.4
Kanasaki, K.5
Koya, D.6
-
68
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
Klionsky DJ, Emr SD. 2000. Autophagy as a regulated pathway of cellular degradation. Science 290:1717-1721.
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
69
-
-
80051796665
-
SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells
-
Koyama T, Kume S, Koya D, Araki SI, Isshiki K, Chin-Kanasaki M, Sugimoto T, Haneda M, Sugaya T, Kashiwagi A, Maegawa H, Uzu T. 2011. SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells. Free Radic Biol Med 51:1258-1267.
-
(2011)
Free Radic Biol Med
, vol.51
, pp. 1258-1267
-
-
Koyama, T.1
Kume, S.2
Koya, D.3
Araki, S.I.4
Isshiki, K.5
Chin-Kanasaki, M.6
Sugimoto, T.7
Haneda, M.8
Sugaya, T.9
Kashiwagi, A.10
Maegawa, H.11
Uzu, T.12
-
70
-
-
78649338141
-
Autophagy and the integrated stress response
-
Kroemer G, Mariño G, Levine B. 2010. Autophagy and the integrated stress response. Mol Cell 40:280-293.
-
(2010)
Mol Cell
, vol.40
, pp. 280-293
-
-
Kroemer, G.1
Mariño, G.2
Levine, B.3
-
71
-
-
77951157657
-
Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney
-
Kume S, Uzu T, Horiike K, Chin-Kanasaki M, Isshiki K, Araki SI, Sugimoto T, Haneda M, Kashiwagi A, Koya D. 2010. Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney. J Clin Invest 120:1043-1055.
-
(2010)
J Clin Invest
, vol.120
, pp. 1043-1055
-
-
Kume, S.1
Uzu, T.2
Horiike, K.3
Chin-Kanasaki, M.4
Isshiki, K.5
Araki, S.I.6
Sugimoto, T.7
Haneda, M.8
Kashiwagi, A.9
Koya, D.10
-
72
-
-
55549096745
-
SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation
-
Lan F, Cacicedo JM, Ruderman N, Ido Y. 2008. SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation. J Biol Chem 283:27628-27635.
-
(2008)
J Biol Chem
, vol.283
, pp. 27628-27635
-
-
Lan, F.1
Cacicedo, J.M.2
Ruderman, N.3
Ido, Y.4
-
73
-
-
41549138483
-
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
-
Lee IH, Cao L, Mostoslavsky R, Lombard DB, Liu J, Bruns NE, Tsokos M, Alt FW, Finkel T. 2008. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc Natl Acad Sci USA 105:3374-3379.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 3374-3379
-
-
Lee, I.H.1
Cao, L.2
Mostoslavsky, R.3
Lombard, D.B.4
Liu, J.5
Bruns, N.E.6
Tsokos, M.7
Alt, F.W.8
Finkel, T.9
-
74
-
-
84865662105
-
Reactive oxygen species regulation of autophagy in cancer: Implications for cancer treatment
-
Li L, Ishdorj G, Gibson SB. 2012. Reactive oxygen species regulation of autophagy in cancer: Implications for cancer treatment. Free Radic Biol Med 53:1399-1410.
-
(2012)
Free Radic Biol Med
, vol.53
, pp. 1399-1410
-
-
Li, L.1
Ishdorj, G.2
Gibson, S.B.3
-
75
-
-
33847793039
-
Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that decelerates cell differentiation through deacetylating alpha-tubulin
-
Li W, Zhang B, Tang J, Cao Q, Wu Y, Wu C, Guo J, Ling EA, Liang F. 2007. Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that decelerates cell differentiation through deacetylating alpha-tubulin. J Neurosci 27:2606-2616.
-
(2007)
J Neurosci
, vol.27
, pp. 2606-2616
-
-
Li, W.1
Zhang, B.2
Tang, J.3
Cao, Q.4
Wu, Y.5
Wu, C.6
Guo, J.7
Ling, E.A.8
Liang, F.9
-
76
-
-
36049049392
-
IRE1 signaling affects cell fate during the unfolded protein response
-
Lin JH, Li H, Yasumura D, Cohen HR, Zhang C, Panning B, Shokat KM, Lavail MM, Walter P. 2007. IRE1 signaling affects cell fate during the unfolded protein response. Science 318:944-949.
-
(2007)
Science
, vol.318
, pp. 944-949
-
-
Lin, J.H.1
Li, H.2
Yasumura, D.3
Cohen, H.R.4
Zhang, C.5
Panning, B.6
Shokat, K.M.7
Lavail, M.M.8
Walter, P.9
-
78
-
-
84862635122
-
Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury
-
Liu S, Hartleben B, Kretz O, Wiech T, Igarashi P, Mizushima N, Walz G, Huber TB. 2012. Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury. Autophagy 8:826-837.
-
(2012)
Autophagy
, vol.8
, pp. 826-837
-
-
Liu, S.1
Hartleben, B.2
Kretz, O.3
Wiech, T.4
Igarashi, P.5
Mizushima, N.6
Walz, G.7
Huber, T.B.8
-
79
-
-
62449178216
-
The critical role of the class III histone deacetylase SIRT1 in cancer
-
Liu T, Liu PY, Marshall GM. 2009. The critical role of the class III histone deacetylase SIRT1 in cancer. Cancer Res 69:1702-1705.
-
(2009)
Cancer Res
, vol.69
, pp. 1702-1705
-
-
Liu, T.1
Liu, P.Y.2
Marshall, G.M.3
-
80
-
-
67549139908
-
Vesicular trafficking and autophagosome formation
-
Longatti A, Tooze SA. 2009. Vesicular trafficking and autophagosome formation. Cell Death Differ 16:956-965.
-
(2009)
Cell Death Differ
, vol.16
, pp. 956-965
-
-
Longatti, A.1
Tooze, S.A.2
-
81
-
-
57349140895
-
Linking sirtuins, IGF-I signaling, and starvation
-
Longo VD. 2009. Linking sirtuins, IGF-I signaling, and starvation. Exp Gerontol 44:70-74.
-
(2009)
Exp Gerontol
, vol.44
, pp. 70-74
-
-
Longo, V.D.1
-
82
-
-
33746228121
-
Sirtuins in aging and age-related disease
-
Longo VD, Kennedy BK. 2006. Sirtuins in aging and age-related disease. Cell 126:257-268.
-
(2006)
Cell
, vol.126
, pp. 257-268
-
-
Longo, V.D.1
Kennedy, B.K.2
-
83
-
-
0035913911
-
Negative control of p53 by Sir2alpha promotes cell survival under stress
-
Luo J, Nikolaev AY, Imai S, Chen D, Su F, Shiloh A, Guarente L, Gu W. 2001. Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell 107:137-148.
-
(2001)
Cell
, vol.107
, pp. 137-148
-
-
Luo, J.1
Nikolaev, A.Y.2
Imai, S.3
Chen, D.4
Su, F.5
Shiloh, A.6
Guarente, L.7
Gu, W.8
-
84
-
-
79954417611
-
Autophagy for tissue homeostasis and neuroprotection
-
Mariño G, Madeo F, Kroemer G. 2011. Autophagy for tissue homeostasis and neuroprotection. Curr Opin Cell Biol 23:198-206.
-
(2011)
Curr Opin Cell Biol
, vol.23
, pp. 198-206
-
-
Mariño, G.1
Madeo, F.2
Kroemer, G.3
-
85
-
-
79551634458
-
Autophagy in tumorigenesis and energy metabolism: Friend by day, foe by night
-
Mathew R, White E. 2011. Autophagy in tumorigenesis and energy metabolism: Friend by day, foe by night. Curr Opin Genet Dev 21:113-119.
-
(2011)
Curr Opin Genet Dev
, vol.21
, pp. 113-119
-
-
Mathew, R.1
White, E.2
-
86
-
-
77954234752
-
Cytosolic Fox O1: Alive and killing
-
Medema RH, Jäättelä M. 2010. Cytosolic Fox O1: Alive and killing. Nat Cell Biol 12:642-643.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 642-643
-
-
Medema, R.H.1
Jäättelä, M.2
-
87
-
-
78649751019
-
The role of ESCRT proteins in fusion events involving lysosomes, endosomes and autophagosomes
-
Metcalf D, Isaacs AM. 2010. The role of ESCRT proteins in fusion events involving lysosomes, endosomes and autophagosomes. Biochem Soc Trans 38:1469-1473.
-
(2010)
Biochem Soc Trans
, vol.38
, pp. 1469-1473
-
-
Metcalf, D.1
Isaacs, A.M.2
-
88
-
-
34249083199
-
Sirtuins in mammals: Insights into their biological function
-
Michan S, Sinclair D. 2007. Sirtuins in mammals: Insights into their biological function. Biochem J 404:1-13.
-
(2007)
Biochem J
, vol.404
, pp. 1-13
-
-
Michan, S.1
Sinclair, D.2
-
89
-
-
79953043473
-
Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy
-
Morselli E, Maiuri MC, Markaki M, Megalou E, Pasparaki A, Palikaras K, Criollo A, Galluzzi L, Malik SA, Vitale I, Michaud M, Madeo F, Tavernarakis N, Kroemer G. 2010. Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy. Cell Death Dis 1:e10.
-
(2010)
Cell Death Dis
, vol.1
-
-
Morselli, E.1
Maiuri, M.C.2
Markaki, M.3
Megalou, E.4
Pasparaki, A.5
Palikaras, K.6
Criollo, A.7
Galluzzi, L.8
Malik, S.A.9
Vitale, I.10
Michaud, M.11
Madeo, F.12
Tavernarakis, N.13
Kroemer, G.14
-
90
-
-
75149128169
-
The life span-prolonging effect of sirtuin-1 is mediated by autophagy
-
Morselli E, Maiuri MC, Markaki M, Megalou E, Pasparaki A, Palikaras K, Criollo A, Galluzzi L, Malik SA, Vitale I, Michaud M, Madeo F, Tavernarakis N, Kroemer G. 2010. The life span-prolonging effect of sirtuin-1 is mediated by autophagy. Autophagy 6:186-188.
-
(2010)
Autophagy
, vol.6
, pp. 186-188
-
-
Morselli, E.1
Maiuri, M.C.2
Markaki, M.3
Megalou, E.4
Pasparaki, A.5
Palikaras, K.6
Criollo, A.7
Galluzzi, L.8
Malik, S.A.9
Vitale, I.10
Michaud, M.11
Madeo, F.12
Tavernarakis, N.13
Kroemer, G.14
-
91
-
-
79951889242
-
Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome
-
Morselli E., et al. 2011. Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome. J Cell Biol 192:615-629.
-
(2011)
J Cell Biol
, vol.192
, pp. 615-629
-
-
Morselli, E.1
-
92
-
-
78549272759
-
Effects of Longevinex (modified resveratrol) on cardioprotection and its mechanisms of action
-
Mukherjee S, Ray D, Lekli I, Bak I, Tosaki A, Das DK. 2010. Effects of Longevinex (modified resveratrol) on cardioprotection and its mechanisms of action. Can J Physiol Pharmacol 88:1017-1025.
-
(2010)
Can J Physiol Pharmacol
, vol.88
, pp. 1017-1025
-
-
Mukherjee, S.1
Ray, D.2
Lekli, I.3
Bak, I.4
Tosaki, A.5
Das, D.K.6
-
93
-
-
80053226539
-
SIRT1-mediated acute cardioprotection
-
Nadtochiy SM, Yao H, McBurney MW, Gu W, Guarente L, Rahman I, Brookes PS. 2011. SIRT1-mediated acute cardioprotection. Am J Physiol Heart Circ Physiol 301:H1506-H1512.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
-
-
Nadtochiy, S.M.1
Yao, H.2
McBurney, M.W.3
Gu, W.4
Guarente, L.5
Rahman, I.6
Brookes, P.S.7
-
94
-
-
77949539030
-
JNK1 phosphorylates SIRT1 and promotes its enzymatic activity
-
Nasrin N, Kaushik VK, Fortier E, Wall D, Pearson KJ, de Cabo R, Bordone L. 2009. JNK1 phosphorylates SIRT1 and promotes its enzymatic activity. PLoS ONE 4:e8414.
-
(2009)
PLoS ONE
, vol.4
-
-
Nasrin, N.1
Kaushik, V.K.2
Fortier, E.3
Wall, D.4
Pearson, K.J.5
de Cabo, R.6
Bordone, L.7
-
95
-
-
77951168796
-
The role of Sirt1 in renal rejuvenation and resistance to stress
-
Nath KA. 2010. The role of Sirt1 in renal rejuvenation and resistance to stress. J Clin Invest 120:1026-1028.
-
(2010)
J Clin Invest
, vol.120
, pp. 1026-1028
-
-
Nath, K.A.1
-
96
-
-
10844236451
-
Nutrient availability regulates SIRT1 through a forkhead-dependent pathway
-
Nemoto S, Fergusson MM, Finkel T. 2004. Nutrient availability regulates SIRT1 through a forkhead-dependent pathway. Science 306:2105-2108.
-
(2004)
Science
, vol.306
, pp. 2105-2108
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
97
-
-
18144411313
-
SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}
-
Nemoto S, Fergusson MM, Finkel T. 2005. SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}. J Biol Chem 280:16456-16460.
-
(2005)
J Biol Chem
, vol.280
, pp. 16456-16460
-
-
Nemoto, S.1
Fergusson, M.M.2
Finkel, T.3
-
98
-
-
84863425313
-
p62 at the interface of autophagy, oxidative stress signaling, and cancer
-
Nezis IP, Stenmark H. 2012. p62 at the interface of autophagy, oxidative stress signaling, and cancer. Antioxid Redox Signal 17:786-793.
-
(2012)
Antioxid Redox Signal
, vol.17
, pp. 786-793
-
-
Nezis, I.P.1
Stenmark, H.2
-
99
-
-
70349687405
-
Discovery of Atg5/Atg7-independent alternative macroautophagy
-
Nishida Y, Arakawa S, Fujitani K, Yamaguchi H, Mizuta T, Kanaseki T, Komatsu M, Otsu K, Tsujimoto Y, Shimizu S. 2009. Discovery of Atg5/Atg7-independent alternative macroautophagy. Nature 461:654-658.
-
(2009)
Nature
, vol.461
, pp. 654-658
-
-
Nishida, Y.1
Arakawa, S.2
Fujitani, K.3
Yamaguchi, H.4
Mizuta, T.5
Kanaseki, T.6
Komatsu, M.7
Otsu, K.8
Tsujimoto, Y.9
Shimizu, S.10
-
100
-
-
67549132527
-
The late stages of autophagy: How does the end begin
-
Noda T, Fujita N, Yoshimori T. 2009. The late stages of autophagy: How does the end begin? Cell Death Differ 16:984-990.
-
(2009)
Cell Death Differ
, vol.16
, pp. 984-990
-
-
Noda, T.1
Fujita, N.2
Yoshimori, T.3
-
101
-
-
0037291214
-
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
-
North BJ, Marshall BL, Borra MT, Denu JM, Verdin E. 2003. The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Mol Cell 11:437-444.
-
(2003)
Mol Cell
, vol.11
, pp. 437-444
-
-
North, B.J.1
Marshall, B.L.2
Borra, M.T.3
Denu, J.M.4
Verdin, E.5
-
102
-
-
77951234553
-
Membrane trafficking events that partake in autophagy
-
Orsi A, Polson HEJ, Tooze SA. 2010. Membrane trafficking events that partake in autophagy. Curr Opin Cell Biol 22:150-156.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 150-156
-
-
Orsi, A.1
Polson, H.E.J.2
Tooze, S.A.3
-
103
-
-
34547599329
-
Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease
-
Outeiro TF, Kontopoulos E, Altmann SM, Kufareva I, Strathearn KE, Amore AM, Volk CB, Maxwell MM, Rochet JC, McLean PJ, Young AB, Abagyan R, Feany MB, Hyman BT, Kazantsev AG. 2007. Sirtuin 2 inhibitors rescue alpha-synuclein-mediated toxicity in models of Parkinson's disease. Science 317:516-519.
-
(2007)
Science
, vol.317
, pp. 516-519
-
-
Outeiro, T.F.1
Kontopoulos, E.2
Altmann, S.M.3
Kufareva, I.4
Strathearn, K.E.5
Amore, A.M.6
Volk, C.B.7
Maxwell, M.M.8
Rochet, J.C.9
McLean, P.J.10
Young, A.B.11
Abagyan, R.12
Feany, M.B.13
Hyman, B.T.14
Kazantsev, A.G.15
-
104
-
-
61849139135
-
Resveratrol and neurodegenerative diseases: Activation of SIRT1 as the potential pathway towards neuroprotection
-
Pallàs M, Casadesús G, Smith MA, Coto-Montes A, Pelegri C, Vilaplana J, Camins A. 2009. Resveratrol and neurodegenerative diseases: Activation of SIRT1 as the potential pathway towards neuroprotection. Curr Neurovasc Res 6:70-81.
-
(2009)
Curr Neurovasc Res
, vol.6
, pp. 70-81
-
-
Pallàs, M.1
Casadesús, G.2
Smith, M.A.3
Coto-Montes, A.4
Pelegri, C.5
Vilaplana, J.6
Camins, A.7
-
105
-
-
40849113090
-
The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility
-
Pandithage R, Lilischkis R, Harting K, Wolf A, Jedamzik B, Lüscher-Firzlaff J, Vervoorts J, Lasonder E, Kremmer E, Knöll B, Lüscher B. 2008. The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility. J Cell Biol 180:915-929.
-
(2008)
J Cell Biol
, vol.180
, pp. 915-929
-
-
Pandithage, R.1
Lilischkis, R.2
Harting, K.3
Wolf, A.4
Jedamzik, B.5
Lüscher-Firzlaff, J.6
Vervoorts, J.7
Lasonder, E.8
Kremmer, E.9
Knöll, B.10
Lüscher, B.11
-
106
-
-
3042681042
-
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma
-
Picard F, Kurtev M, Chung N, Topark-Ngarm A, Senawong T, Machado De Oliveira R, Leid M, McBurney MW, Guarente L. 2004. Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma. Nature 429:771-776.
-
(2004)
Nature
, vol.429
, pp. 771-776
-
-
Picard, F.1
Kurtev, M.2
Chung, N.3
Topark-Ngarm, A.4
Senawong, T.5
Machado De Oliveira, R.6
Leid, M.7
McBurney, M.W.8
Guarente, L.9
-
107
-
-
79551521179
-
Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation
-
Powell MJ, Casimiro MC, Cordon-Cardo C, He X, Yeow WS, Wang C, McCue PA, McBurney MW, Pestell RG. 2011. Disruption of a Sirt1-dependent autophagy checkpoint in the prostate results in prostatic intraepithelial neoplasia lesion formation. Cancer Res 71:964-975.
-
(2011)
Cancer Res
, vol.71
, pp. 964-975
-
-
Powell, M.J.1
Casimiro, M.C.2
Cordon-Cardo, C.3
He, X.4
Yeow, W.S.5
Wang, C.6
McCue, P.A.7
McBurney, M.W.8
Pestell, R.G.9
-
108
-
-
79953666939
-
Acute induction of autophagy as a novel strategy for cardioprotection: Getting to the heart of the matter
-
Przyklenk K, Undyala VVR, Wider J, Sala-Mercado JA, Gottlieb RA, Mentzer RM. 2011. Acute induction of autophagy as a novel strategy for cardioprotection: Getting to the heart of the matter. Autophagy 7:432-433.
-
(2011)
Autophagy
, vol.7
, pp. 432-433
-
-
Przyklenk, K.1
Undyala, V.V.R.2
Wider, J.3
Sala-Mercado, J.A.4
Gottlieb, R.A.5
Mentzer, R.M.6
-
109
-
-
33746824192
-
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction
-
Qin W, Yang T, Ho L, Zhao Z, Wang J, Chen L, Zhao W, Thiyagarajan M, MacGrogan D, Rodgers JT, Puigserver P, Sadoshima J, Deng H, Pedrini S, Gandy S, Sauve AA, Pasinetti GM. 2006. Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. J Biol Chem 281:21745-21754.
-
(2006)
J Biol Chem
, vol.281
, pp. 21745-21754
-
-
Qin, W.1
Yang, T.2
Ho, L.3
Zhao, Z.4
Wang, J.5
Chen, L.6
Zhao, W.7
Thiyagarajan, M.8
MacGrogan, D.9
Rodgers, J.T.10
Puigserver, P.11
Sadoshima, J.12
Deng, H.13
Pedrini, S.14
Gandy, S.15
Sauve, A.A.16
Pasinetti, G.M.17
-
111
-
-
0346503885
-
The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure
-
Reggiori F, Tucker KA, Stromhaug PE, Klionsky DJ. 2004. The Atg1-Atg13 complex regulates Atg9 and Atg23 retrieval transport from the pre-autophagosomal structure. Dev Cell 6:79-90.
-
(2004)
Dev Cell
, vol.6
, pp. 79-90
-
-
Reggiori, F.1
Tucker, K.A.2
Stromhaug, P.E.3
Klionsky, D.J.4
-
112
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. 2005. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434:113-118.
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
113
-
-
8644224064
-
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
-
Rogina B, Helfand SL. 2004. Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc Natl Acad Sci USA 101:15998-16003.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 15998-16003
-
-
Rogina, B.1
Helfand, S.L.2
-
114
-
-
79957883170
-
The multiple roles of autophagy in cancer
-
Rosenfeldt MT, Ryan KM. 2011. The multiple roles of autophagy in cancer. Carcinogenesis 32:955-963.
-
(2011)
Carcinogenesis
, vol.32
, pp. 955-963
-
-
Rosenfeldt, M.T.1
Ryan, K.M.2
-
115
-
-
53149100858
-
SIRT1 longevity factor suppresses NF-kappaB-driven immune responses: Regulation of aging via NF-kappaB acetylation
-
Salminen A, Kauppinen A, Suuronen T, Kaarniranta K. 2008. SIRT1 longevity factor suppresses NF-kappaB-driven immune responses: Regulation of aging via NF-kappaB acetylation? Bioessays 30:939-942.
-
(2008)
Bioessays
, vol.30
, pp. 939-942
-
-
Salminen, A.1
Kauppinen, A.2
Suuronen, T.3
Kaarniranta, K.4
-
116
-
-
84867280590
-
SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy
-
Sampaio-Marques B, Felgueiras C, Silva A, Rodrigues M, Tenreiro S, Franssens V, Reichert AS, Outeiro TF, Winderickx J, Ludovico P. 2012. SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy. Autophagy 8:1494-1509.
-
(2012)
Autophagy
, vol.8
, pp. 1494-1509
-
-
Sampaio-Marques, B.1
Felgueiras, C.2
Silva, A.3
Rodrigues, M.4
Tenreiro, S.5
Franssens, V.6
Reichert, A.S.7
Outeiro, T.F.8
Winderickx, J.9
Ludovico, P.10
-
117
-
-
65449186232
-
Atg17 recruits Atg9 to organize the pre-autophagosomal structure
-
Sekito T, Kawamata T, Ichikawa R, Suzuki K, Ohsumi Y. 2009. Atg17 recruits Atg9 to organize the pre-autophagosomal structure. Genes Cells 14:525-538.
-
(2009)
Genes Cells
, vol.14
, pp. 525-538
-
-
Sekito, T.1
Kawamata, T.2
Ichikawa, R.3
Suzuki, K.4
Ohsumi, Y.5
-
118
-
-
79953186624
-
FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress
-
Sengupta A, Molkentin JD, Paik JH, DePinho RA, Yutzey KE. 2011. FoxO transcription factors promote cardiomyocyte survival upon induction of oxidative stress. J Biol Chem 286:7468-7478.
-
(2011)
J Biol Chem
, vol.286
, pp. 7468-7478
-
-
Sengupta, A.1
Molkentin, J.D.2
Paik, J.H.3
DePinho, R.A.4
Yutzey, K.E.5
-
119
-
-
70350500068
-
FoxO transcription factors promote autophagy in cardiomyocytes
-
Sengupta A, Molkentin JD, Yutzey KE. 2009. FoxO transcription factors promote autophagy in cardiomyocytes. J Biol Chem 284:28319-28331.
-
(2009)
J Biol Chem
, vol.284
, pp. 28319-28331
-
-
Sengupta, A.1
Molkentin, J.D.2
Yutzey, K.E.3
-
120
-
-
84863677794
-
Vam3, a derivative of resveratrol, attenuates cigarette smoke-induced autophagy
-
Shi J, Yin N, Xuan LL, Yao CS, Meng AM, Hou Q. 2012. Vam3, a derivative of resveratrol, attenuates cigarette smoke-induced autophagy. Acta Pharmacol Sin 33:888-896.
-
(2012)
Acta Pharmacol Sin
, vol.33
, pp. 888-896
-
-
Shi, J.1
Yin, N.2
Xuan, L.L.3
Yao, C.S.4
Meng, A.M.5
Hou, Q.6
-
121
-
-
84870895663
-
Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions
-
Son SM, Song H, Byun J, Park KS, Jang HC, Park YJ, Mook-Jung I. 2012. Accumulation of autophagosomes contributes to enhanced amyloidogenic APP processing under insulin-resistant conditions. Autophagy 8.
-
(2012)
Autophagy
, pp. 8
-
-
Son, S.M.1
Song, H.2
Byun, J.3
Park, K.S.4
Jang, H.C.5
Park, Y.J.6
Mook-Jung, I.7
-
122
-
-
84872839736
-
Mutant SOD1(G93A) triggers mitochondrial fragmentation in spinal cord motor neurons: Neuroprotection by SIRT3 and PGC-1α
-
Song W, Song Y, Kincaid B, Bossy B, Bossy-Wetzel E. 2012. Mutant SOD1(G93A) triggers mitochondrial fragmentation in spinal cord motor neurons: Neuroprotection by SIRT3 and PGC-1α. Neurobiol Dis.
-
(2012)
Neurobiol Dis.
-
-
Song, W.1
Song, Y.2
Kincaid, B.3
Bossy, B.4
Bossy-Wetzel, E.5
-
123
-
-
79951881254
-
Protective roles of SIRT1 in atherosclerosis
-
Stein S, Matter CM. 2011. Protective roles of SIRT1 in atherosclerosis. Cell Cycle 10:640-647.
-
(2011)
Cell Cycle
, vol.10
, pp. 640-647
-
-
Stein, S.1
Matter, C.M.2
-
125
-
-
70349208608
-
Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice
-
Sundaresan NR, Gupta M, Kim G, Rajamohan SB, Isbatan A, Gupta MP. 2009. Sirt3 blocks the cardiac hypertrophic response by augmenting Foxo3a-dependent antioxidant defense mechanisms in mice. J Clin Invest 119:2758-2771.
-
(2009)
J Clin Invest
, vol.119
, pp. 2758-2771
-
-
Sundaresan, N.R.1
Gupta, M.2
Kim, G.3
Rajamohan, S.B.4
Isbatan, A.5
Gupta, M.P.6
-
126
-
-
80052799903
-
Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy
-
Sundaresan NR, Pillai VB, Gupta MP. 2011. Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy. J Mol Cell Cardiol 51:614-618.
-
(2011)
J Mol Cell Cardiol
, vol.51
, pp. 614-618
-
-
Sundaresan, N.R.1
Pillai, V.B.2
Gupta, M.P.3
-
127
-
-
53549105529
-
SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70
-
Sundaresan NR, Samant SA, Pillai VB, Rajamohan SB, Gupta MP. 2008. SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. Mol Cell Biol 28:6384-6401.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 6384-6401
-
-
Sundaresan, N.R.1
Samant, S.A.2
Pillai, V.B.3
Rajamohan, S.B.4
Gupta, M.P.5
-
128
-
-
34250848194
-
Mammalian Sir2-related protein (SIRT) 2-mediated modulation of resistance to axonal degeneration in slow Wallerian degeneration mice: A crucial role of tubulin deacetylation
-
Suzuki K, Koike T. 2007. Mammalian Sir2-related protein (SIRT) 2-mediated modulation of resistance to axonal degeneration in slow Wallerian degeneration mice: A crucial role of tubulin deacetylation. Neuroscience 147:599-612.
-
(2007)
Neuroscience
, vol.147
, pp. 599-612
-
-
Suzuki, K.1
Koike, T.2
-
129
-
-
67549096696
-
Bif-1/endophilin B1: A candidate for crescent driving force in autophagy
-
Takahashi Y, Meyerkord CL, Wang HG. 2009. Bif-1/endophilin B1: A candidate for crescent driving force in autophagy Cell Death Differ 16:947-955.
-
(2009)
Cell Death Differ
, vol.16
, pp. 947-955
-
-
Takahashi, Y.1
Meyerkord, C.L.2
Wang, H.G.3
-
130
-
-
77049098395
-
Sirt1's complex roles in Neuroprotection
-
Tang BL. 2009. Sirt1's complex roles in Neuroprotection. Cell Mol Neurobiol 29:1093-1103.
-
(2009)
Cell Mol Neurobiol
, vol.29
, pp. 1093-1103
-
-
Tang, B.L.1
-
131
-
-
79954494901
-
Sirt1's systemic protective roles and its promise as a target in antiaging medicine
-
Tang BL. 2011. Sirt1's systemic protective roles and its promise as a target in antiaging medicine. Transl Res 157:276-284.
-
(2011)
Transl Res
, vol.157
, pp. 276-284
-
-
Tang, B.L.1
-
133
-
-
50249145608
-
A dual role of p53 in the control of autophagy
-
Tasdemir E, Chiara Maiuri M, Morselli E, Criollo A, D'Amelio M, Djavaheri-Mergny M, Cecconi F, Tavernarakis N, Kroemer G. 2008. A dual role of p53 in the control of autophagy. Autophagy 4:810-814.
-
(2008)
Autophagy
, vol.4
, pp. 810-814
-
-
Tasdemir, E.1
Chiara Maiuri, M.2
Morselli, E.3
Criollo, A.4
D'Amelio, M.5
Djavaheri-Mergny, M.6
Cecconi, F.7
Tavernarakis, N.8
Kroemer, G.9
-
134
-
-
44649141966
-
Regulation of autophagy by cytoplasmic p53
-
Tasdemir E., et al. 2008. Regulation of autophagy by cytoplasmic p53. Nat Cell Biol 10:676-687.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 676-687
-
-
Tasdemir, E.1
-
135
-
-
53649084026
-
p53 represses autophagy in a cell cycle-dependent fashion
-
Tasdemir E, Maiuri MC, Orhon I, Kepp O, Morselli E, Criollo A, Kroemer G. 2008. p53 represses autophagy in a cell cycle-dependent fashion. Cell Cycle 7:3006-3011.
-
(2008)
Cell Cycle
, vol.7
, pp. 3006-3011
-
-
Tasdemir, E.1
Maiuri, M.C.2
Orhon, I.3
Kepp, O.4
Morselli, E.5
Criollo, A.6
Kroemer, G.7
-
136
-
-
84863328591
-
The journey of resveratrol from yeast to human
-
Timmer S, Auwerx J, Schrauwen P. 2012. The journey of resveratrol from yeast to human. Aging 4:146-158.
-
(2012)
Aging
, vol.4
, pp. 146-158
-
-
Timmer, S.1
Auwerx, J.2
Schrauwen, P.3
-
137
-
-
77956414236
-
The origin of the autophagosomal membrane
-
Tooze SA, Yoshimori T. 2010. The origin of the autophagosomal membrane. Nat Cell Biol 12:831-835.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 831-835
-
-
Tooze, S.A.1
Yoshimori, T.2
-
138
-
-
80053606380
-
Impact of caloric and dietary restriction regimens on markers of health and longevity in humans and animals: A summary of available findings
-
Trepanowski JF, Canale RE, Marshall KE, Kabir MM, Bloomer RJ. 2011. Impact of caloric and dietary restriction regimens on markers of health and longevity in humans and animals: A summary of available findings. Nutr J 10:107.
-
(2011)
Nutr J
, vol.10
, pp. 107
-
-
Trepanowski, J.F.1
Canale, R.E.2
Marshall, K.E.3
Kabir, M.M.4
Bloomer, R.J.5
-
139
-
-
84855424390
-
Interplay between histone deacetylases and autophagy-From cancer therapy to neurodegeneration
-
Trüe O, Matthias P. 2012. Interplay between histone deacetylases and autophagy-From cancer therapy to neurodegeneration. Immunol Cell Biol 90:78-784.
-
(2012)
Immunol Cell Biol
, vol.90
, pp. 78-784
-
-
Trüe, O.1
Matthias, P.2
-
141
-
-
0035913903
-
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
-
Vaziri H, Dessain SK, Ng Eaton E, Imai SI, Frye RA, Pandita TK, Guarente L, Weinberg RA. 2001. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107:149-159.
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng Eaton, E.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.A.8
-
142
-
-
84855860714
-
mIGF-1/JNK1/SirT1 signaling confers protection against oxidative stress in the heart
-
Vinciguerra M, Santini MP, Martinez C, Pazienza V, Claycomb WC, Giuliani A, Rosenthal N. 2012. mIGF-1/JNK1/SirT1 signaling confers protection against oxidative stress in the heart. Aging Cell 11:139-149.
-
(2012)
Aging Cell
, vol.11
, pp. 139-149
-
-
Vinciguerra, M.1
Santini, M.P.2
Martinez, C.3
Pazienza, V.4
Claycomb, W.C.5
Giuliani, A.6
Rosenthal, N.7
-
143
-
-
25444442080
-
Triple layer control: Phosphorylation, acetylation and ubiquitination of FOXO proteins
-
Vogt PK, Jiang H, Aoki M. 2005. Triple layer control: Phosphorylation, acetylation and ubiquitination of FOXO proteins. Cell Cycle 4:908-913.
-
(2005)
Cell Cycle
, vol.4
, pp. 908-913
-
-
Vogt, P.K.1
Jiang, H.2
Aoki, M.3
-
144
-
-
34447626095
-
SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction
-
Wang F, Nguyen M, Qin FXF, Tong Q. 2007. SIRT2 deacetylates FOXO3a in response to oxidative stress and caloric restriction. Aging Cell 6:505-514.
-
(2007)
Aging Cell
, vol.6
, pp. 505-514
-
-
Wang, F.1
Nguyen, M.2
Qin, F.X.F.3
Tong, Q.4
-
145
-
-
84865037340
-
Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells
-
Wang J, Kim TH, Ahn MY, Lee J, Jung JH, Choi WS, Lee BM, Yoon KS, Yoon S, Kim HS. 2012. Sirtinol, a class III HDAC inhibitor, induces apoptotic and autophagic cell death in MCF-7 human breast cancer cells. Int J Oncol 41:1101-1109.
-
(2012)
Int J Oncol
, vol.41
, pp. 1101-1109
-
-
Wang, J.1
Kim, T.H.2
Ahn, M.Y.3
Lee, J.4
Jung, J.H.5
Choi, W.S.6
Lee, B.M.7
Yoon, K.S.8
Yoon, S.9
Kim, H.S.10
-
146
-
-
84863012215
-
Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia
-
Wang P, Guan YF, Du H, Zhai QW, Su DF, Miao CY. 2012. Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia. Autophagy 8:77-87.
-
(2012)
Autophagy
, vol.8
, pp. 77-87
-
-
Wang, P.1
Guan, Y.F.2
Du, H.3
Zhai, Q.W.4
Su, D.F.5
Miao, C.Y.6
-
147
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, Tatar M, Sinclair D. 2004. Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 430:686-689.
-
(2004)
Nature
, vol.430
, pp. 686-689
-
-
Wood, J.G.1
Rogina, B.2
Lavu, S.3
Howitz, K.4
Helfand, S.L.5
Tatar, M.6
Sinclair, D.7
-
148
-
-
80052359850
-
Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease
-
Wu Y, Li X, Zhu JX, Xie W, Le W, Fan Z, Jankovic J, Pan T. 2011. Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease. Neurosignals 19:163-174.
-
(2011)
Neurosignals
, vol.19
, pp. 163-174
-
-
Wu, Y.1
Li, X.2
Zhu, J.X.3
Xie, W.4
Le, W.5
Fan, Z.6
Jankovic, J.7
Pan, T.8
-
149
-
-
78649299872
-
Autophagy in the central nervous system: Implications for neurodegenerative disorders
-
Xilouri M, Stefanis L. 2010. Autophagy in the central nervous system: Implications for neurodegenerative disorders. CNS Neurol Disord Drug Targets 9:701-719.
-
(2010)
CNS Neurol Disord Drug Targets
, vol.9
, pp. 701-719
-
-
Xilouri, M.1
Stefanis, L.2
-
150
-
-
79951720176
-
JNK regulates FoxO-dependent autophagy in neurons
-
Xu P, Das M, Reilly J, Davis RJ. 2011. JNK regulates FoxO-dependent autophagy in neurons. Genes Dev 25:310-322.
-
(2011)
Genes Dev
, vol.25
, pp. 310-322
-
-
Xu, P.1
Das, M.2
Reilly, J.3
Davis, R.J.4
-
151
-
-
77956404377
-
Eaten alive: A history of macroautophagy
-
Yang Z, Klionsky DJ. 2010. Eaten alive: A history of macroautophagy. Nat Cell Biol 12:814-822.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 814-822
-
-
Yang, Z.1
Klionsky, D.J.2
-
152
-
-
77951214016
-
Mammalian autophagy: Core molecular machinery and signaling regulation
-
Yang Z, Klionsky DJ. 2010. Mammalian autophagy: Core molecular machinery and signaling regulation. Curr Opin Cell Biol 22:124-131.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 124-131
-
-
Yang, Z.1
Klionsky, D.J.2
-
153
-
-
3242719545
-
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase
-
Yeung F, Hoberg JE, Ramsey CS, Keller MD, Jones DR, Frye RA, Mayo MW. 2004. Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase. EMBO J 23:2369-2380.
-
(2004)
EMBO J
, vol.23
, pp. 2369-2380
-
-
Yeung, F.1
Hoberg, J.E.2
Ramsey, C.S.3
Keller, M.D.4
Jones, D.R.5
Frye, R.A.6
Mayo, M.W.7
-
154
-
-
77953292238
-
SIRT1 and p53, effect on cancer, senescence and beyond
-
Yi J, Luo J. 2010. SIRT1 and p53, effect on cancer, senescence and beyond. Biochim Biophys Acta 1804:1684-1689.
-
(2010)
Biochim Biophys Acta
, vol.1804
, pp. 1684-1689
-
-
Yi, J.1
Luo, J.2
-
155
-
-
33750366092
-
Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes
-
Young ARJ, Chan EYW, Hu XW, Köchl R, Crawshaw SG, High S, Hailey DW, Lippincott-Schwartz J, Tooze SA. 2006. Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes. J Cell Sci 119:3888-3900.
-
(2006)
J Cell Sci
, vol.119
, pp. 3888-3900
-
-
Young, A.R.J.1
Chan, E.Y.W.2
Hu, X.W.3
Köchl, R.4
Crawshaw, S.G.5
High, S.6
Hailey, D.W.7
Lippincott-Schwartz, J.8
Tooze, S.A.9
-
156
-
-
84882967613
-
Autophagic cell death: A new frontier in cancer research
-
Zappavigna S, Luce A, Vitale G, Merola N, Facchini S, Caraglia M. 2013. Autophagic cell death: A new frontier in cancer research. Adv Biosci Biotech 4:250-262.
-
(2013)
Adv Biosci Biotech
, vol.4
, pp. 250-262
-
-
Zappavigna, S.1
Luce, A.2
Vitale, G.3
Merola, N.4
Facchini, S.5
Caraglia, M.6
-
157
-
-
84855468411
-
Autophagy counteracts apoptosis in human multiple myeloma cells exposed to oridonin in vitro via regulating intracellular ROS and SIRT1
-
Zeng R, Chen Y, Zhao S, Cui GH. 2012. Autophagy counteracts apoptosis in human multiple myeloma cells exposed to oridonin in vitro via regulating intracellular ROS and SIRT1. Acta Pharmacol Sin 33:91-100.
-
(2012)
Acta Pharmacol Sin
, vol.33
, pp. 91-100
-
-
Zeng, R.1
Chen, Y.2
Zhao, S.3
Cui, G.H.4
-
158
-
-
84857371921
-
The time-dependent autophagy protects against apoptosis with possible involvement of Sirt1 protein in multiple myeloma under nutrient depletion
-
Zeng R, He J, Peng J, Chen Y, Yi S, Zhao F, Cui G. 2012. The time-dependent autophagy protects against apoptosis with possible involvement of Sirt1 protein in multiple myeloma under nutrient depletion. Ann Hematol 91:407-417.
-
(2012)
Ann Hematol
, vol.91
, pp. 407-417
-
-
Zeng, R.1
He, J.2
Peng, J.3
Chen, Y.4
Yi, S.5
Zhao, F.6
Cui, G.7
-
159
-
-
80054123174
-
Protective effects and mechanisms of sirtuins in the nervous system
-
Zhang F, Wang S, Gan L, Vosler PS, Gao Y, Zigmond MJ, Chen J. 2011. Protective effects and mechanisms of sirtuins in the nervous system. Prog Neurobiol 95:373-395.
-
(2011)
Prog Neurobiol
, vol.95
, pp. 373-395
-
-
Zhang, F.1
Wang, S.2
Gan, L.3
Vosler, P.S.4
Gao, Y.5
Zigmond, M.J.6
Chen, J.7
-
160
-
-
77954225200
-
Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity
-
Zhao Y, Yang J, Liao W, Liu X, Zhang H, Wang S, Wang D, Feng J, Yu L, Zhu WG. 2010. Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity. Nat Cell Biol 12:665-675.
-
(2010)
Nat Cell Biol
, vol.12
, pp. 665-675
-
-
Zhao, Y.1
Yang, J.2
Liao, W.3
Liu, X.4
Zhang, H.5
Wang, S.6
Wang, D.7
Feng, J.8
Yu, L.9
Zhu, W.G.10
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