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Volumn 37, Issue , 2013, Pages 114-140

Photoreceptor cell death and rescue in retinal detachment and degenerations

Author keywords

Apoptosis; Autophagy; Degenerations; Macula; Necrosis; Neuroprotection; Neuroregeneration; Retina

Indexed keywords

CASPASE 11; CASPASE 12; CASPASE 14; CASPASE 2; CASPASE 3; CASPASE 6; CASPASE 7; CASPASE 8; CASPASE 9; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN; PROTEIN BCL 2; RIP1 PROTEIN; UNCLASSIFIED DRUG;

EID: 84887407104     PISSN: 13509462     EISSN: 18731635     Source Type: Journal    
DOI: 10.1016/j.preteyeres.2013.08.001     Document Type: Review
Times cited : (191)

References (351)
  • 2
    • 33845425645 scopus 로고    scopus 로고
    • Crystallins in the eye: function and pathology
    • Andley U.P. Crystallins in the eye: function and pathology. Prog. Retin Eye Res. 2007, 26:78-98.
    • (2007) Prog. Retin Eye Res. , vol.26 , pp. 78-98
    • Andley, U.P.1
  • 4
    • 17144390258 scopus 로고    scopus 로고
    • Photoreceptor apoptosis in human retinal detachment
    • Arroyo J.G., Yang L., Bula D., Chen D.F. Photoreceptor apoptosis in human retinal detachment. Am. J. Ophthalmol. 2005, 139:605-610.
    • (2005) Am. J. Ophthalmol. , vol.139 , pp. 605-610
    • Arroyo, J.G.1    Yang, L.2    Bula, D.3    Chen, D.F.4
  • 7
    • 0030626755 scopus 로고    scopus 로고
    • [Concentration of selected cytokines in subretinal fluid in patients with retinal detachment (IL-8, TNF-alpha, IFN-gamma)]
    • Bakunowicz-Lazarczyk A., Moniuszko T., Stankiewicz A., Mrugacz M. [Concentration of selected cytokines in subretinal fluid in patients with retinal detachment (IL-8, TNF-alpha, IFN-gamma)]. Klin. Oczna. 1997, 99:87-89.
    • (1997) Klin. Oczna. , vol.99 , pp. 87-89
    • Bakunowicz-Lazarczyk, A.1    Moniuszko, T.2    Stankiewicz, A.3    Mrugacz, M.4
  • 8
    • 0032529103 scopus 로고    scopus 로고
    • Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin
    • Barber A.J., Lieth E., Khin S.A., Antonetti D.A., Buchanan A.G., Gardner T.W. Neural apoptosis in the retina during experimental and human diabetes. Early onset and effect of insulin. J.Clin. Invest. 1998, 102:783-791.
    • (1998) J.Clin. Invest. , vol.102 , pp. 783-791
    • Barber, A.J.1    Lieth, E.2    Khin, S.A.3    Antonetti, D.A.4    Buchanan, A.G.5    Gardner, T.W.6
  • 10
    • 77951247275 scopus 로고    scopus 로고
    • Inhibition of retinal detachment-induced apoptosis in photoreceptors by a small peptide inhibitor of the fas receptor
    • Besirli C.G., Chinskey N.D., Zheng Q.D., Zacks D.N. Inhibition of retinal detachment-induced apoptosis in photoreceptors by a small peptide inhibitor of the fas receptor. Invest. Ophthalmol. Vis. Sci. 2010, 51:2177-2184.
    • (2010) Invest. Ophthalmol. Vis. Sci. , vol.51 , pp. 2177-2184
    • Besirli, C.G.1    Chinskey, N.D.2    Zheng, Q.D.3    Zacks, D.N.4
  • 11
    • 80051935718 scopus 로고    scopus 로고
    • Autophagy activation in the injured photoreceptor inhibits fas-mediated apoptosis
    • Besirli C.G., Chinskey N.D., Zheng Q.D., Zacks D.N. Autophagy activation in the injured photoreceptor inhibits fas-mediated apoptosis. Invest. Ophthalmol. Vis. Sci. 2011, 52:4193-4199.
    • (2011) Invest. Ophthalmol. Vis. Sci. , vol.52 , pp. 4193-4199
    • Besirli, C.G.1    Chinskey, N.D.2    Zheng, Q.D.3    Zacks, D.N.4
  • 12
    • 79953282304 scopus 로고    scopus 로고
    • NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-alpha feedforward signaling
    • Biton S., Ashkenazi A. NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-alpha feedforward signaling. Cell 2011, 145:92-103.
    • (2011) Cell , vol.145 , pp. 92-103
    • Biton, S.1    Ashkenazi, A.2
  • 13
    • 27944504351 scopus 로고    scopus 로고
    • P62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
    • Bjorkoy G., Lamark T., Brech A., Outzen H., Perander M., Overvatn A., Stenmark H., Johansen T. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J.Cell Biol. 2005, 171:603-614.
    • (2005) J.Cell Biol. , vol.171 , pp. 603-614
    • Bjorkoy, G.1    Lamark, T.2    Brech, A.3    Outzen, H.4    Perander, M.5    Overvatn, A.6    Stenmark, H.7    Johansen, T.8
  • 14
    • 8044257699 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes
    • Blommaart E.F., Krause U., Schellens J.P., Vreeling-Sindelarova H., Meijer A.J. The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes. Eur. J. Biochem./FEBS 1997, 243:240-246.
    • (1997) Eur. J. Biochem./FEBS , vol.243 , pp. 240-246
    • Blommaart, E.F.1    Krause, U.2    Schellens, J.P.3    Vreeling-Sindelarova, H.4    Meijer, A.J.5
  • 15
    • 0038662649 scopus 로고    scopus 로고
    • Caspase-3 inhibitor reduces apototic photoreceptor cell death during inherited retinal degeneration in tubby mice
    • Bode C., Wolfrum U. Caspase-3 inhibitor reduces apototic photoreceptor cell death during inherited retinal degeneration in tubby mice. Mol. Vis. 2003, 9:144-150.
    • (2003) Mol. Vis. , vol.9 , pp. 144-150
    • Bode, C.1    Wolfrum, U.2
  • 18
  • 21
    • 33746912767 scopus 로고    scopus 로고
    • The permeability transition pore complex in cancer cell death
    • Brenner C., Grimm S. The permeability transition pore complex in cancer cell death. Oncogene 2006, 25:4744-4756.
    • (2006) Oncogene , vol.25 , pp. 4744-4756
    • Brenner, C.1    Grimm, S.2
  • 24
    • 33745864334 scopus 로고    scopus 로고
    • Deficiency in apoptotic effectors Bax and Bak reveals an autophagic cell death pathway initiated by photodamage to the endoplasmic reticulum
    • Buytaert E., Callewaert G., Vandenheede J.R., Agostinis P. Deficiency in apoptotic effectors Bax and Bak reveals an autophagic cell death pathway initiated by photodamage to the endoplasmic reticulum. Autophagy 2006, 2:238-240.
    • (2006) Autophagy , vol.2 , pp. 238-240
    • Buytaert, E.1    Callewaert, G.2    Vandenheede, J.R.3    Agostinis, P.4
  • 25
    • 33845472476 scopus 로고    scopus 로고
    • Caspase inhibitors: viral, cellular and chemical
    • Callus B.A., Vaux D.L. Caspase inhibitors: viral, cellular and chemical. Cell Death Differ. 2007, 14:73-78.
    • (2007) Cell Death Differ. , vol.14 , pp. 73-78
    • Callus, B.A.1    Vaux, D.L.2
  • 26
    • 0037623521 scopus 로고    scopus 로고
    • The Rapamune era of immunosuppression 2003: the journey from the laboratory to clinical transplantation
    • Camardo J. The Rapamune era of immunosuppression 2003: the journey from the laboratory to clinical transplantation. Transplant Proc. 2003, 35:18S-24S.
    • (2003) Transplant Proc. , vol.35
    • Camardo, J.1
  • 29
    • 80052265428 scopus 로고    scopus 로고
    • Macrophage polarization in the maculae of age-related macular degeneration: a pilot study
    • Cao X., Shen D., Patel M.M., Tuo J., Johnson T.M., Olsen T.W., Chan C.C. Macrophage polarization in the maculae of age-related macular degeneration: a pilot study. Pathol. Int. 2011, 61:528-535.
    • (2011) Pathol. Int. , vol.61 , pp. 528-535
    • Cao, X.1    Shen, D.2    Patel, M.M.3    Tuo, J.4    Johnson, T.M.5    Olsen, T.W.6    Chan, C.C.7
  • 32
    • 0032544449 scopus 로고    scopus 로고
    • Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development
    • Cecconi F., Alvarez-Bolado G., Meyer B.I., Roth K.A., Gruss P. Apaf1 (CED-4 homolog) regulates programmed cell death in mammalian development. Cell 1998, 94:727-737.
    • (1998) Cell , vol.94 , pp. 727-737
    • Cecconi, F.1    Alvarez-Bolado, G.2    Meyer, B.I.3    Roth, K.A.4    Gruss, P.5
  • 33
    • 0347065342 scopus 로고    scopus 로고
    • Arole for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses
    • Chan F.K., Shisler J., Bixby J.G., Felices M., Zheng L., Appel M., Orenstein J., Moss B., Lenardo M.J. Arole for tumor necrosis factor receptor-2 and receptor-interacting protein in programmed necrosis and antiviral responses. J.Biol. Chem. 2003, 278:51613-51621.
    • (2003) J.Biol. Chem. , vol.278 , pp. 51613-51621
    • Chan, F.K.1    Shisler, J.2    Bixby, J.G.3    Felices, M.4    Zheng, L.5    Appel, M.6    Orenstein, J.7    Moss, B.8    Lenardo, M.J.9
  • 34
    • 0027521914 scopus 로고
    • Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice
    • Chang G.Q., Hao Y., Wong F. Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice. Neuron 1993, 11:595-605.
    • (1993) Neuron , vol.11 , pp. 595-605
    • Chang, G.Q.1    Hao, Y.2    Wong, F.3
  • 36
    • 70349472923 scopus 로고    scopus 로고
    • Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production
    • Chang M., Jin W., Sun S.C. Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production. Nat. Immunol. 2009, 10:1089-1095.
    • (2009) Nat. Immunol. , vol.10 , pp. 1089-1095
    • Chang, M.1    Jin, W.2    Sun, S.C.3
  • 37
    • 84865842787 scopus 로고    scopus 로고
    • Fas ligand-Fas signaling participates in light-induced apoptotic death in photoreceptor cells
    • Chang Q., Peter M.E., Grassi M.A. Fas ligand-Fas signaling participates in light-induced apoptotic death in photoreceptor cells. Invest. Ophthalmol. Vis. Sci. 2012, 53:3703-3716.
    • (2012) Invest. Ophthalmol. Vis. Sci. , vol.53 , pp. 3703-3716
    • Chang, Q.1    Peter, M.E.2    Grassi, M.A.3
  • 42
    • 66449133280 scopus 로고    scopus 로고
    • Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
    • Cho Y.S., Challa S., Moquin D., Genga R., Ray T.D., Guildford M., Chan F.K. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 2009, 137:1112-1123.
    • (2009) Cell , vol.137 , pp. 1112-1123
    • Cho, Y.S.1    Challa, S.2    Moquin, D.3    Genga, R.4    Ray, T.D.5    Guildford, M.6    Chan, F.K.7
  • 43
    • 80051481307 scopus 로고    scopus 로고
    • RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation
    • Cho Y., McQuade T., Zhang H., Zhang J., Chan F.K. RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation. PLoS One 2011, 6:e23209.
    • (2011) PLoS One , vol.6
    • Cho, Y.1    McQuade, T.2    Zhang, H.3    Zhang, J.4    Chan, F.K.5
  • 46
    • 41949083926 scopus 로고    scopus 로고
    • Redox-dependent changes in molecular properties of mitochondrial apoptosis-inducing factor
    • Churbanova I.Y., Sevrioukova I.F. Redox-dependent changes in molecular properties of mitochondrial apoptosis-inducing factor. J.Biol. Chem. 2008, 283:5622-5631.
    • (2008) J.Biol. Chem. , vol.283 , pp. 5622-5631
    • Churbanova, I.Y.1    Sevrioukova, I.F.2
  • 47
    • 0025283961 scopus 로고
    • Developmental cell death: morphological diversity and multiple mechanisms
    • Clarke P.G. Developmental cell death: morphological diversity and multiple mechanisms. Anat. Embryol. (Berl) 1990, 181:195-213.
    • (1990) Anat. Embryol. (Berl) , vol.181 , pp. 195-213
    • Clarke, P.G.1
  • 48
    • 0026344133 scopus 로고
    • Prevention of apoptosis by a baculovirus gene during infection of insect cells
    • Clem R.J., Fechheimer M., Miller L.K. Prevention of apoptosis by a baculovirus gene during infection of insect cells. Science 1991, 254:1388-1390.
    • (1991) Science , vol.254 , pp. 1388-1390
    • Clem, R.J.1    Fechheimer, M.2    Miller, L.K.3
  • 49
    • 0028935279 scopus 로고
    • Apoptotic photoreceptor degeneration in experimental retinal detachment
    • Cook B., Lewis G.P., Fisher S.K., Adler R. Apoptotic photoreceptor degeneration in experimental retinal detachment. Invest. Ophthalmol. Vis. Sci. 1995, 36:990-996.
    • (1995) Invest. Ophthalmol. Vis. Sci. , vol.36 , pp. 990-996
    • Cook, B.1    Lewis, G.P.2    Fisher, S.K.3    Adler, R.4
  • 50
    • 0027537461 scopus 로고
    • An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif
    • Crook N.E., Clem R.J., Miller L.K. An apoptosis-inhibiting baculovirus gene with a zinc finger-like motif. J.Virol. 1993, 67:2168-2174.
    • (1993) J.Virol. , vol.67 , pp. 2168-2174
    • Crook, N.E.1    Clem, R.J.2    Miller, L.K.3
  • 51
    • 79957438570 scopus 로고    scopus 로고
    • Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice
    • Csak T., Dolganiuc A., Kodys K., Nath B., Petrasek J., Bala S., Lippai D., Szabo G. Mitochondrial antiviral signaling protein defect links impaired antiviral response and liver injury in steatohepatitis in mice. Hepatology 2011, 53:1917-1931.
    • (2011) Hepatology , vol.53 , pp. 1917-1931
    • Csak, T.1    Dolganiuc, A.2    Kodys, K.3    Nath, B.4    Petrasek, J.5    Bala, S.6    Lippai, D.7    Szabo, G.8
  • 52
    • 27744476223 scopus 로고    scopus 로고
    • Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia
    • Culmsee C., Zhu C., Landshamer S., Becattini B., Wagner E., Pellecchia M., Blomgren K., Plesnila N. Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia. J.Neurosci. 2005, 25:10262-10272.
    • (2005) J.Neurosci. , vol.25 , pp. 10262-10272
    • Culmsee, C.1    Zhu, C.2    Landshamer, S.3    Becattini, B.4    Wagner, E.5    Pellecchia, M.6    Blomgren, K.7    Plesnila, N.8
  • 53
    • 27744561393 scopus 로고    scopus 로고
    • Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation
    • Cusson-Hermance N., Khurana S., Lee T.H., Fitzgerald K.A., Kelliher M.A. Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-{kappa}B activation but does not contribute to interferon regulatory factor 3 activation. J.Biol. Chem. 2005, 280:36560-36566.
    • (2005) J.Biol. Chem. , vol.280 , pp. 36560-36566
    • Cusson-Hermance, N.1    Khurana, S.2    Lee, T.H.3    Fitzgerald, K.A.4    Kelliher, M.A.5
  • 57
    • 33749440219 scopus 로고    scopus 로고
    • Age-related macular degeneration
    • de Jong P.T. Age-related macular degeneration. N.Engl. J. Med. 2006, 355:1474-1485.
    • (2006) N.Engl. J. Med. , vol.355 , pp. 1474-1485
    • de Jong, P.T.1
  • 61
    • 84872310440 scopus 로고    scopus 로고
    • Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase
    • Degterev A., Maki J.L., Yuan J. Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase. Cell Death Differ. 2013, 20:366.
    • (2013) Cell Death Differ. , vol.20 , pp. 366
    • Degterev, A.1    Maki, J.L.2    Yuan, J.3
  • 63
    • 43049105074 scopus 로고    scopus 로고
    • To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions
    • Dewson G., Kratina T., Sim H.W., Puthalakath H., Adams J.M., Colman P.M., Kluck R.M. To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions. Mol. Cell 2008, 30:369-380.
    • (2008) Mol. Cell , vol.30 , pp. 369-380
    • Dewson, G.1    Kratina, T.2    Sim, H.W.3    Puthalakath, H.4    Adams, J.M.5    Colman, P.M.6    Kluck, R.M.7
  • 64
    • 84868089350 scopus 로고    scopus 로고
    • Necrostatin-1 protects photoreceptors from cell death and improves functional outcome after experimental retinal detachment
    • Dong K., Zhu H., Song Z., Gong Y., Wang F., Wang W., Zheng Z., Yu Z., Gu Q., Xu X., Sun X. Necrostatin-1 protects photoreceptors from cell death and improves functional outcome after experimental retinal detachment. Am. J. Pathol. 2012, 181:1634-1641.
    • (2012) Am. J. Pathol. , vol.181 , pp. 1634-1641
    • Dong, K.1    Zhu, H.2    Song, Z.3    Gong, Y.4    Wang, F.5    Wang, W.6    Zheng, Z.7    Yu, Z.8    Gu, Q.9    Xu, X.10    Sun, X.11
  • 65
    • 0036850537 scopus 로고    scopus 로고
    • Caspase-independent photoreceptor apoptosis invivo and differential expression of apoptotic protease activating factor-1 and caspase-3 during retinal development
    • Donovan M., Cotter T.G. Caspase-independent photoreceptor apoptosis invivo and differential expression of apoptotic protease activating factor-1 and caspase-3 during retinal development. Cell Death Differ. 2002, 9:1220-1231.
    • (2002) Cell Death Differ. , vol.9 , pp. 1220-1231
    • Donovan, M.1    Cotter, T.G.2
  • 66
    • 0037707639 scopus 로고    scopus 로고
    • Caspase-independent photoreceptor apoptosis in mouse models of retinal degeneration
    • Doonan F., Donovan M., Cotter T.G. Caspase-independent photoreceptor apoptosis in mouse models of retinal degeneration. J.Neurosci. 2003, 23:5723-5731.
    • (2003) J.Neurosci. , vol.23 , pp. 5723-5731
    • Doonan, F.1    Donovan, M.2    Cotter, T.G.3
  • 67
    • 35148897262 scopus 로고    scopus 로고
    • Bim expression indicates the pathway to retinal cell death in development and degeneration
    • Doonan F., Donovan M., Gomez-Vicente V., Bouillet P., Cotter T.G. Bim expression indicates the pathway to retinal cell death in development and degeneration. J.Neurosci. 2007, 27:10887-10894.
    • (2007) J.Neurosci. , vol.27 , pp. 10887-10894
    • Doonan, F.1    Donovan, M.2    Gomez-Vicente, V.3    Bouillet, P.4    Cotter, T.G.5
  • 69
    • 0034616945 scopus 로고    scopus 로고
    • Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
    • Du C., Fang M., Li Y., Li L., Wang X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell 2000, 102:33-42.
    • (2000) Cell , vol.102 , pp. 33-42
    • Du, C.1    Fang, M.2    Li, Y.3    Li, L.4    Wang, X.5
  • 70
  • 72
    • 33646034316 scopus 로고    scopus 로고
    • Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO
    • Ea C.K., Deng L., Xia Z.P., Pineda G., Chen Z.J. Activation of IKK by TNFalpha requires site-specific ubiquitination of RIP1 and polyubiquitin binding by NEMO. Mol. Cell 2006, 22:245-257.
    • (2006) Mol. Cell , vol.22 , pp. 245-257
    • Ea, C.K.1    Deng, L.2    Xia, Z.P.3    Pineda, G.4    Chen, Z.J.5
  • 73
    • 0022497852 scopus 로고
    • Genetic control of programmed cell death in the nematode C.elegans
    • Ellis H.M., Horvitz H.R. Genetic control of programmed cell death in the nematode C.elegans. Cell 1986, 44:817-829.
    • (1986) Cell , vol.44 , pp. 817-829
    • Ellis, H.M.1    Horvitz, H.R.2
  • 75
    • 38949136372 scopus 로고    scopus 로고
    • To be or not to be? Examples of incorrect identification of autophagic compartments in conventional transmission electron microscopy of mammalian cells
    • Eskelinen E.L. To be or not to be? Examples of incorrect identification of autophagic compartments in conventional transmission electron microscopy of mammalian cells. Autophagy 2008, 4:257-260.
    • (2008) Autophagy , vol.4 , pp. 257-260
    • Eskelinen, E.L.1
  • 76
    • 34548437549 scopus 로고    scopus 로고
    • Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain
    • Feng S., Yang Y., Mei Y., Ma L., Zhu D.E., Hoti N., Castanares M., Wu M. Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain. Cell Signal 2007, 19:2056-2067.
    • (2007) Cell Signal , vol.19 , pp. 2056-2067
    • Feng, S.1    Yang, Y.2    Mei, Y.3    Ma, L.4    Zhu, D.E.5    Hoti, N.6    Castanares, M.7    Wu, M.8
  • 79
    • 22744437978 scopus 로고    scopus 로고
    • Apoptosis-based therapies and drug targets
    • Fischer U., Schulze-Osthoff K. Apoptosis-based therapies and drug targets. Cell Death Differ. 2005, 12(Suppl.1):942-961.
    • (2005) Cell Death Differ. , vol.12 , Issue.SUPPL.1 , pp. 942-961
    • Fischer, U.1    Schulze-Osthoff, K.2
  • 81
    • 58249114977 scopus 로고    scopus 로고
    • Prothymosin-alpha plays a defensive role in retinal ischemia through necrosis and apoptosis inhibition
    • Fujita R., Ueda M., Fujiwara K., Ueda H. Prothymosin-alpha plays a defensive role in retinal ischemia through necrosis and apoptosis inhibition. Cell Death Differ. 2009, 16:349-358.
    • (2009) Cell Death Differ. , vol.16 , pp. 349-358
    • Fujita, R.1    Ueda, M.2    Fujiwara, K.3    Ueda, H.4
  • 82
    • 84856495152 scopus 로고    scopus 로고
    • Targeting IAP proteins for therapeutic intervention in cancer
    • Fulda S., Vucic D. Targeting IAP proteins for therapeutic intervention in cancer. Nat. Rev. Drug Discov. 2012, 11:109-124.
    • (2012) Nat. Rev. Drug Discov. , vol.11 , pp. 109-124
    • Fulda, S.1    Vucic, D.2
  • 83
    • 57649167477 scopus 로고    scopus 로고
    • Necroptosis: a specialized pathway of programmed necrosis
    • Galluzzi L., Kroemer G. Necroptosis: a specialized pathway of programmed necrosis. Cell 2008, 135:1161-1163.
    • (2008) Cell , vol.135 , pp. 1161-1163
    • Galluzzi, L.1    Kroemer, G.2
  • 86
    • 78149449341 scopus 로고    scopus 로고
    • BH3-triggered structural reorganization drives the activation of proapoptotic BAX
    • Gavathiotis E., Reyna D.E., Davis M.L., Bird G.H., Walensky L.D. BH3-triggered structural reorganization drives the activation of proapoptotic BAX. Mol. Cell 2010, 40:481-492.
    • (2010) Mol. Cell , vol.40 , pp. 481-492
    • Gavathiotis, E.1    Reyna, D.E.2    Davis, M.L.3    Bird, G.H.4    Walensky, L.D.5
  • 87
    • 0026648674 scopus 로고
    • Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
    • Gavrieli Y., Sherman Y., Ben-Sasson S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J.Cell Biol. 1992, 119:493-501.
    • (1992) J.Cell Biol. , vol.119 , pp. 493-501
    • Gavrieli, Y.1    Sherman, Y.2    Ben-Sasson, S.A.3
  • 88
    • 0029090167 scopus 로고
    • Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity
    • Goossens V., Grooten J., De Vos K., Fiers W. Direct evidence for tumor necrosis factor-induced mitochondrial reactive oxygen intermediates and their involvement in cytotoxicity. Proc. Natl. Acad. Sci. U. S. A. 1995, 92:8115-8119.
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 8115-8119
    • Goossens, V.1    Grooten, J.2    De Vos, K.3    Fiers, W.4
  • 89
    • 0029294613 scopus 로고
    • In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note
    • Grasl-Kraupp B., Ruttkay-Nedecky B., Koudelka H., Bukowska K., Bursch W., Schulte-Hermann R. In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note. Hepatology 1995, 21:1465-1468.
    • (1995) Hepatology , vol.21 , pp. 1465-1468
    • Grasl-Kraupp, B.1    Ruttkay-Nedecky, B.2    Koudelka, H.3    Bukowska, K.4    Bursch, W.5    Schulte-Hermann, R.6
  • 90
    • 80053580530 scopus 로고    scopus 로고
    • RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts
    • Green D.R., Oberst A., Dillon C.P., Weinlich R., Salvesen G.S. RIPK-dependent necrosis and its regulation by caspases: a mystery in five acts. Mol. Cell 2011, 44:9-16.
    • (2011) Mol. Cell , vol.44 , pp. 9-16
    • Green, D.R.1    Oberst, A.2    Dillon, C.P.3    Weinlich, R.4    Salvesen, G.S.5
  • 91
    • 0034105724 scopus 로고    scopus 로고
    • Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration
    • Grimm C., Wenzel A., Hafezi F., Yu S., Redmond T.M., Reme C.E. Protection of Rpe65-deficient mice identifies rhodopsin as a mediator of light-induced retinal degeneration. Nat. Genet. 2000, 25:63-66.
    • (2000) Nat. Genet. , vol.25 , pp. 63-66
    • Grimm, C.1    Wenzel, A.2    Hafezi, F.3    Yu, S.4    Redmond, T.M.5    Reme, C.E.6
  • 95
    • 84864466372 scopus 로고    scopus 로고
    • The Bcl-2 family member BIM has multiple glaucoma-relevant functions in DBA/2J mice
    • Harder J.M., Fernandes K.A., Libby R.T. The Bcl-2 family member BIM has multiple glaucoma-relevant functions in DBA/2J mice. Sci. Rep. 2012, 2:530.
    • (2012) Sci. Rep. , vol.2 , pp. 530
    • Harder, J.M.1    Fernandes, K.A.2    Libby, R.T.3
  • 97
    • 84872308031 scopus 로고    scopus 로고
    • Arole for c-FLIP(L) in the regulation of apoptosis, autophagy, and necroptosis in T lymphocytes
    • He M.X., He Y.W. Arole for c-FLIP(L) in the regulation of apoptosis, autophagy, and necroptosis in T lymphocytes. Cell Death Differ. 2013, 20:188-197.
    • (2013) Cell Death Differ. , vol.20 , pp. 188-197
    • He, M.X.1    He, Y.W.2
  • 98
    • 66749183275 scopus 로고    scopus 로고
    • Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
    • He S., Wang L., Miao L., Wang T., Du F., Zhao L., Wang X. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 2009, 137:1100-1111.
    • (2009) Cell , vol.137 , pp. 1100-1111
    • He, S.1    Wang, L.2    Miao, L.3    Wang, T.4    Du, F.5    Zhao, L.6    Wang, X.7
  • 99
    • 84055181328 scopus 로고    scopus 로고
    • Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway
    • He S., Liang Y., Shao F., Wang X. Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:20054-20059.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 20054-20059
    • He, S.1    Liang, Y.2    Shao, F.3    Wang, X.4
  • 100
    • 0141893347 scopus 로고    scopus 로고
    • Rapid, noninflammatory and PS-dependent phagocytic clearance of necrotic cells
    • Hirt U.A., Leist M. Rapid, noninflammatory and PS-dependent phagocytic clearance of necrotic cells. Cell Death Differ. 2003, 10:1156-1164.
    • (2003) Cell Death Differ. , vol.10 , pp. 1156-1164
    • Hirt, U.A.1    Leist, M.2
  • 102
    • 0038243885 scopus 로고    scopus 로고
    • Clearance of apoptotic photoreceptors: elimination of apoptotic debris into the subretinal space and macrophage-mediated phagocytosis via phosphatidylserine receptor and integrin alphavbeta3
    • Hisatomi T., Sakamoto T., Sonoda K.H., Tsutsumi C., Qiao H., Enaida H., Yamanaka I., Kubota T., Ishibashi T., Kura S., Susin S.A., Kroemer G. Clearance of apoptotic photoreceptors: elimination of apoptotic debris into the subretinal space and macrophage-mediated phagocytosis via phosphatidylserine receptor and integrin alphavbeta3. Am. J. Pathol. 2003, 162:1869-1879.
    • (2003) Am. J. Pathol. , vol.162 , pp. 1869-1879
    • Hisatomi, T.1    Sakamoto, T.2    Sonoda, K.H.3    Tsutsumi, C.4    Qiao, H.5    Enaida, H.6    Yamanaka, I.7    Kubota, T.8    Ishibashi, T.9    Kura, S.10    Susin, S.A.11    Kroemer, G.12
  • 104
    • 57649181391 scopus 로고    scopus 로고
    • Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway
    • Hitomi J., Christofferson D.E., Ng A., Yao J., Degterev A., Xavier R.J., Yuan J. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell 2008, 135:1311-1323.
    • (2008) Cell , vol.135 , pp. 1311-1323
    • Hitomi, J.1    Christofferson, D.E.2    Ng, A.3    Yao, J.4    Degterev, A.5    Xavier, R.J.6    Yuan, J.7
  • 105
    • 2142810153 scopus 로고    scopus 로고
    • Characterization of IDN-6556 (3-[2-(2-tert-butyl-phenylaminooxalyl)-amino]-propionylamino]-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid): a liver-targeted caspase inhibitor
    • Hoglen N.C., Chen L.S., Fisher C.D., Hirakawa B.P., Groessl T., Contreras P.C. Characterization of IDN-6556 (3-[2-(2-tert-butyl-phenylaminooxalyl)-amino]-propionylamino]-4-oxo-5-(2,3,5,6-tetrafluoro-phenoxy)-pentanoic acid): a liver-targeted caspase inhibitor. J.Pharmacol. Exp. Ther. 2004, 309:634-640.
    • (2004) J.Pharmacol. Exp. Ther. , vol.309 , pp. 634-640
    • Hoglen, N.C.1    Chen, L.S.2    Fisher, C.D.3    Hirakawa, B.P.4    Groessl, T.5    Contreras, P.C.6
  • 109
    • 0030963602 scopus 로고    scopus 로고
    • Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis
    • Hsu Y.T., Wolter K.G., Youle R.J. Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis. Proc. Natl. Acad. Sci. U. S. A. 1997, 94:3668-3672.
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 3668-3672
    • Hsu, Y.T.1    Wolter, K.G.2    Youle, R.J.3
  • 110
    • 0035831022 scopus 로고    scopus 로고
    • Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain
    • Huang Y., Park Y.C., Rich R.L., Segal D., Myszka D.G., Wu H. Structural basis of caspase inhibition by XIAP: differential roles of the linker versus the BIR domain. Cell 2001, 104:781-790.
    • (2001) Cell , vol.104 , pp. 781-790
    • Huang, Y.1    Park, Y.C.2    Rich, R.L.3    Segal, D.4    Myszka, D.G.5    Wu, H.6
  • 111
    • 33845439096 scopus 로고    scopus 로고
    • Dynamic role of postsynaptic caspase-3 and BIRC4 in zebra finch song-response habituation
    • Huesmann G.R., Clayton D.F. Dynamic role of postsynaptic caspase-3 and BIRC4 in zebra finch song-response habituation. Neuron 2006, 52:1061-1072.
    • (2006) Neuron , vol.52 , pp. 1061-1072
    • Huesmann, G.R.1    Clayton, D.F.2
  • 112
    • 84862113237 scopus 로고    scopus 로고
    • Apoptotic and non-apoptotic roles of caspases in neuronal physiology and pathophysiology
    • Hyman B.T., Yuan J. Apoptotic and non-apoptotic roles of caspases in neuronal physiology and pathophysiology. Nat. Rev. Neurosci. 2012, 13:395-406.
    • (2012) Nat. Rev. Neurosci. , vol.13 , pp. 395-406
    • Hyman, B.T.1    Yuan, J.2
  • 114
    • 0034307757 scopus 로고    scopus 로고
    • Pigment epithelium-derived factor supports normal development of photoreceptor neurons and opsin expression after retinal pigment epithelium removal
    • Jablonski M.M., Tombran-Tink J., Mrazek D.A., Iannaccone A. Pigment epithelium-derived factor supports normal development of photoreceptor neurons and opsin expression after retinal pigment epithelium removal. J.Neurosci. 2000, 20:7149-7157.
    • (2000) J.Neurosci. , vol.20 , pp. 7149-7157
    • Jablonski, M.M.1    Tombran-Tink, J.2    Mrazek, D.A.3    Iannaccone, A.4
  • 115
    • 0037015020 scopus 로고    scopus 로고
    • The Alzheimer's A beta -peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration
    • Johnson L.V., Leitner W.P., Rivest A.J., Staples M.K., Radeke M.J., Anderson D.H. The Alzheimer's A beta -peptide is deposited at sites of complement activation in pathologic deposits associated with aging and age-related macular degeneration. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:11830-11835.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 11830-11835
    • Johnson, L.V.1    Leitner, W.P.2    Rivest, A.J.3    Staples, M.K.4    Radeke, M.J.5    Anderson, D.H.6
  • 116
    • 58149385608 scopus 로고    scopus 로고
    • Leukemia inhibitory factor extends the lifespan of injured photoreceptors invivo
    • Joly S., Lange C., Thiersch M., Samardzija M., Grimm C. Leukemia inhibitory factor extends the lifespan of injured photoreceptors invivo. J.Neurosci. 2008, 28:13765-13774.
    • (2008) J.Neurosci. , vol.28 , pp. 13765-13774
    • Joly, S.1    Lange, C.2    Thiersch, M.3    Samardzija, M.4    Grimm, C.5
  • 117
    • 0035159897 scopus 로고    scopus 로고
    • Characterization of cell death pathways in murine retinal neurodegeneration implicates cytochrome c release, caspase activation, and bid cleavage
    • Jomary C., Neal M.J., Jones S.E. Characterization of cell death pathways in murine retinal neurodegeneration implicates cytochrome c release, caspase activation, and bid cleavage. Mol. Cell Neurosci. 2001, 18:335-346.
    • (2001) Mol. Cell Neurosci. , vol.18 , pp. 335-346
    • Jomary, C.1    Neal, M.J.2    Jones, S.E.3
  • 118
    • 0032556548 scopus 로고    scopus 로고
    • Expression of alphaB-crystallin in a mouse model of inherited retinal degeneration
    • Jones S.E., Jomary C., Grist J., Thomas M.R., Neal M.J. Expression of alphaB-crystallin in a mouse model of inherited retinal degeneration. Neuroreport 1998, 9:4161-4165.
    • (1998) Neuroreport , vol.9 , pp. 4161-4165
    • Jones, S.E.1    Jomary, C.2    Grist, J.3    Thomas, M.R.4    Neal, M.J.5
  • 119
    • 4344561190 scopus 로고    scopus 로고
    • NF-kappaB is essential for induction of CYLD, the negative regulator of NF-kappaB: evidence for a novel inducible autoregulatory feedback pathway
    • Jono H., Lim J.H., Chen L.F., Xu H., Trompouki E., Pan Z.K., Mosialos G., Li J.D. NF-kappaB is essential for induction of CYLD, the negative regulator of NF-kappaB: evidence for a novel inducible autoregulatory feedback pathway. J.Biol. Chem. 2004, 279:36171-36174.
    • (2004) J.Biol. Chem. , vol.279 , pp. 36171-36174
    • Jono, H.1    Lim, J.H.2    Chen, L.F.3    Xu, H.4    Trompouki, E.5    Pan, Z.K.6    Mosialos, G.7    Li, J.D.8
  • 120
    • 0029801850 scopus 로고    scopus 로고
    • Overexpression of Bcl-2 or Bcl-XL transgenes and photoreceptor degeneration
    • Joseph R.M., Li T. Overexpression of Bcl-2 or Bcl-XL transgenes and photoreceptor degeneration. Invest. Ophthalmol. Vis. Sci. 1996, 37:2434-2446.
    • (1996) Invest. Ophthalmol. Vis. Sci. , vol.37 , pp. 2434-2446
    • Joseph, R.M.1    Li, T.2
  • 123
    • 33847120760 scopus 로고    scopus 로고
    • Subcellular localization of Daxx determines its opposing functions in ischemic cell death
    • Jung Y.S., Kim H.Y., Lee Y.J., Kim E. Subcellular localization of Daxx determines its opposing functions in ischemic cell death. FEBS Lett. 2007, 581:843-852.
    • (2007) FEBS Lett. , vol.581 , pp. 843-852
    • Jung, Y.S.1    Kim, H.Y.2    Lee, Y.J.3    Kim, E.4
  • 124
    • 70350433798 scopus 로고    scopus 로고
    • Interferon-gamma-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells
    • Jurgens B., Hainz U., Fuchs D., Felzmann T., Heitger A. Interferon-gamma-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells. Blood 2009, 114:3235-3243.
    • (2009) Blood , vol.114 , pp. 3235-3243
    • Jurgens, B.1    Hainz, U.2    Fuchs, D.3    Felzmann, T.4    Heitger, A.5
  • 128
    • 33847008972 scopus 로고    scopus 로고
    • DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells
    • Katayama M., Kawaguchi T., Berger M.S., Pieper R.O. DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells. Cell Death Differ. 2007, 14:548-558.
    • (2007) Cell Death Differ. , vol.14 , pp. 548-558
    • Katayama, M.1    Kawaguchi, T.2    Berger, M.S.3    Pieper, R.O.4
  • 129
    • 79952754823 scopus 로고    scopus 로고
    • Heat shock protein 70 (HSP70) is critical for the photoreceptor stress response after retinal detachment via modulating anti-apoptotic Akt kinase
    • Kayama M., Nakazawa T., Thanos A., Morizane Y., Murakami Y., Theodoropoulou S., Abe T., Vavvas D., Miller J.W. Heat shock protein 70 (HSP70) is critical for the photoreceptor stress response after retinal detachment via modulating anti-apoptotic Akt kinase. Am. J. Pathol. 2011, 178:1080-1091.
    • (2011) Am. J. Pathol. , vol.178 , pp. 1080-1091
    • Kayama, M.1    Nakazawa, T.2    Thanos, A.3    Morizane, Y.4    Murakami, Y.5    Theodoropoulou, S.6    Abe, T.7    Vavvas, D.8    Miller, J.W.9
  • 130
  • 131
    • 0015383455 scopus 로고
    • Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr J.F., Wyllie A.H., Currie A.R. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br. J. Cancer 1972, 26:239-257.
    • (1972) Br. J. Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 132
    • 33746701380 scopus 로고    scopus 로고
    • P2X receptors as cell-surface ATP sensors in health and disease
    • Khakh B.S., North R.A. P2X receptors as cell-surface ATP sensors in health and disease. Nature 2006, 442:527-532.
    • (2006) Nature , vol.442 , pp. 527-532
    • Khakh, B.S.1    North, R.A.2
  • 133
    • 70350558453 scopus 로고    scopus 로고
    • Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord
    • Kigerl K.A., Gensel J.C., Ankeny D.P., Alexander J.K., Donnelly D.J., Popovich P.G. Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord. J.Neurosci. 2009, 29:13435-13444.
    • (2009) J.Neurosci. , vol.29 , pp. 13435-13444
    • Kigerl, K.A.1    Gensel, J.C.2    Ankeny, D.P.3    Alexander, J.K.4    Donnelly, D.J.5    Popovich, P.G.6
  • 134
    • 34249820757 scopus 로고    scopus 로고
    • TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death
    • Kim Y.S., Morgan M.J., Choksi S., Liu Z.G. TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death. Mol. Cell 2007, 26:675-687.
    • (2007) Mol. Cell , vol.26 , pp. 675-687
    • Kim, Y.S.1    Morgan, M.J.2    Choksi, S.3    Liu, Z.G.4
  • 135
    • 0034676037 scopus 로고    scopus 로고
    • The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway
    • Kirisako T., Ichimura Y., Okada H., Kabeya Y., Mizushima N., Yoshimori T., Ohsumi M., Takao T., Noda T., Ohsumi Y. The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J.Cell Biol. 2000, 151:263-276.
    • (2000) J.Cell Biol. , vol.151 , pp. 263-276
    • Kirisako, T.1    Ichimura, Y.2    Okada, H.3    Kabeya, Y.4    Mizushima, N.5    Yoshimori, T.6    Ohsumi, M.7    Takao, T.8    Noda, T.9    Ohsumi, Y.10
  • 140
    • 33847134493 scopus 로고    scopus 로고
    • Apoptosis-inducing factor: a matter of neuron life and death
    • Krantic S., Mechawar N., Reix S., Quirion R. Apoptosis-inducing factor: a matter of neuron life and death. Prog. Neurobiol. 2007, 81:179-196.
    • (2007) Prog. Neurobiol. , vol.81 , pp. 179-196
    • Krantic, S.1    Mechawar, N.2    Reix, S.3    Quirion, R.4
  • 141
    • 0026699666 scopus 로고
    • Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements
    • Krikos A., Laherty C.D., Dixit V.M. Transcriptional activation of the tumor necrosis factor alpha-inducible zinc finger protein, A20, is mediated by kappa B elements. J.Biol. Chem. 1992, 267:17971-17976.
    • (1992) J.Biol. Chem. , vol.267 , pp. 17971-17976
    • Krikos, A.1    Laherty, C.D.2    Dixit, V.M.3
  • 142
    • 56749170677 scopus 로고    scopus 로고
    • Autophagic cell death: the story of a misnomer
    • Kroemer G., Levine B. Autophagic cell death: the story of a misnomer. Nat. Rev. Mol. Cell Biol. 2008, 9:1004-1010.
    • (2008) Nat. Rev. Mol. Cell Biol. , vol.9 , pp. 1004-1010
    • Kroemer, G.1    Levine, B.2
  • 144
    • 3343013154 scopus 로고    scopus 로고
    • Phosphatidylserine exposure during early primary necrosis (oncosis) in JB6 cells as evidenced by immunogold labeling technique
    • Krysko O., De Ridder L., Cornelissen M. Phosphatidylserine exposure during early primary necrosis (oncosis) in JB6 cells as evidenced by immunogold labeling technique. Apoptosis 2004, 9:495-500.
    • (2004) Apoptosis , vol.9 , pp. 495-500
    • Krysko, O.1    De Ridder, L.2    Cornelissen, M.3
  • 145
    • 0028920863 scopus 로고
    • Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme
    • Kuida K., Lippke J.A., Ku G., Harding M.W., Livingston D.J., Su M.S., Flavell R.A. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science 1995, 267:2000-2003.
    • (1995) Science , vol.267 , pp. 2000-2003
    • Kuida, K.1    Lippke, J.A.2    Ku, G.3    Harding, M.W.4    Livingston, D.J.5    Su, M.S.6    Flavell, R.A.7
  • 147
    • 34548068863 scopus 로고    scopus 로고
    • Apoptosis and autophagy in photoreceptors exposed to oxidative stress
    • Kunchithapautham K., Rohrer B. Apoptosis and autophagy in photoreceptors exposed to oxidative stress. Autophagy 2007, 3:433-441.
    • (2007) Autophagy , vol.3 , pp. 433-441
    • Kunchithapautham, K.1    Rohrer, B.2
  • 148
    • 33746363831 scopus 로고    scopus 로고
    • Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning
    • Kuo C.T., Zhu S., Younger S., Jan L.Y., Jan Y.N. Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning. Neuron 2006, 51:283-290.
    • (2006) Neuron , vol.51 , pp. 283-290
    • Kuo, C.T.1    Zhu, S.2    Younger, S.3    Jan, L.Y.4    Jan, Y.N.5
  • 150
    • 0023697978 scopus 로고
    • Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis
    • Laster S.M., Wood J.G., Gooding L.R. Tumor necrosis factor can induce both apoptic and necrotic forms of cell lysis. J.Immunol. 1988, 141:2629-2634.
    • (1988) J.Immunol. , vol.141 , pp. 2629-2634
    • Laster, S.M.1    Wood, J.G.2    Gooding, L.R.3
  • 151
    • 84872977087 scopus 로고    scopus 로고
    • Daxx is a key downstream component of receptor interacting protein kinase 3 mediating retinal ischemic cell death
    • Lee Y.S., Dayma Y., Park M.Y., Kim K.I., Yoo S.E., Kim E. Daxx is a key downstream component of receptor interacting protein kinase 3 mediating retinal ischemic cell death. FEBS Lett. 2013, 587:266-271.
    • (2013) FEBS Lett. , vol.587 , pp. 266-271
    • Lee, Y.S.1    Dayma, Y.2    Park, M.Y.3    Kim, K.I.4    Yoo, S.E.5    Kim, E.6
  • 152
    • 0037418238 scopus 로고    scopus 로고
    • JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
    • Lei K., Davis R.J. JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc. Natl. Acad. Sci. U. S. A. 2003, 100:2432-2437.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 2432-2437
    • Lei, K.1    Davis, R.J.2
  • 154
    • 33244471589 scopus 로고    scopus 로고
    • Developmental apoptosis in C.elegans: a complex CEDnario
    • Lettre G., Hengartner M.O. Developmental apoptosis in C.elegans: a complex CEDnario. Nat. Rev. Mol. Cell Biol. 2006, 7:97-108.
    • (2006) Nat. Rev. Mol. Cell Biol. , vol.7 , pp. 97-108
    • Lettre, G.1    Hengartner, M.O.2
  • 155
    • 0028142138 scopus 로고
    • Rapid changes in the expression of glial cell proteins caused by experimental retinal detachment
    • Lewis G.P., Guerin C.J., Anderson D.H., Matsumoto B., Fisher S.K. Rapid changes in the expression of glial cell proteins caused by experimental retinal detachment. Am. J. Ophthalmol. 1994, 118:368-376.
    • (1994) Am. J. Ophthalmol. , vol.118 , pp. 368-376
    • Lewis, G.P.1    Guerin, C.J.2    Anderson, D.H.3    Matsumoto, B.4    Fisher, S.K.5
  • 156
    • 54249096028 scopus 로고    scopus 로고
    • Caspases in apoptosis and beyond
    • Li J., Yuan J. Caspases in apoptosis and beyond. Oncogene 2008, 27:6194-6206.
    • (2008) Oncogene , vol.27 , pp. 6194-6206
    • Li, J.1    Yuan, J.2
  • 157
    • 0028984948 scopus 로고
    • Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock
    • Li P., Allen H., Banerjee S., Franklin S., Herzog L., Johnston C., McDowell J., Paskind M., Rodman L., Salfeld J., et al. Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock. Cell 1995, 80:401-411.
    • (1995) Cell , vol.80 , pp. 401-411
    • Li, P.1    Allen, H.2    Banerjee, S.3    Franklin, S.4    Herzog, L.5    Johnston, C.6    McDowell, J.7    Paskind, M.8    Rodman, L.9    Salfeld, J.10
  • 158
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997, 91:479-489.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3    Srinivasula, S.M.4    Ahmad, M.5    Alnemri, E.S.6    Wang, X.7
  • 159
    • 0032555697 scopus 로고    scopus 로고
    • Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis
    • Li H., Zhu H., Xu C.J., Yuan J. Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis. Cell 1998, 94:491-501.
    • (1998) Cell , vol.94 , pp. 491-501
    • Li, H.1    Zhu, H.2    Xu, C.J.3    Yuan, J.4
  • 160
    • 6344287496 scopus 로고    scopus 로고
    • Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis
    • Li Y., Johnson N., Capano M., Edwards M., Crompton M. Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis. Biochem. J. 2004, 383:101-109.
    • (2004) Biochem. J. , vol.383 , pp. 101-109
    • Li, Y.1    Johnson, N.2    Capano, M.3    Edwards, M.4    Crompton, M.5
  • 161
    • 77951228261 scopus 로고    scopus 로고
    • Receptor interacting protein 3 suppresses vascular smooth muscle cell growth by inhibition of the phosphoinositide 3-kinase-Akt axis
    • Li Q., Li G., Lan X., Zheng M., Chen K.H., Cao C.M., Xiao R.P. Receptor interacting protein 3 suppresses vascular smooth muscle cell growth by inhibition of the phosphoinositide 3-kinase-Akt axis. J.Biol. Chem. 2010, 285:9535-9544.
    • (2010) J.Biol. Chem. , vol.285 , pp. 9535-9544
    • Li, Q.1    Li, G.2    Lan, X.3    Zheng, M.4    Chen, K.H.5    Cao, C.M.6    Xiao, R.P.7
  • 162
    • 77953271477 scopus 로고    scopus 로고
    • Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization
    • Li Z., Jo J., Jia J.M., Lo S.C., Whitcomb D.J., Jiao S., Cho K., Sheng M. Caspase-3 activation via mitochondria is required for long-term depression and AMPA receptor internalization. Cell 2010, 141:859-871.
    • (2010) Cell , vol.141 , pp. 859-871
    • Li, Z.1    Jo, J.2    Jia, J.M.3    Lo, S.C.4    Whitcomb, D.J.5    Jiao, S.6    Cho, K.7    Sheng, M.8
  • 163
    • 0033214236 scopus 로고    scopus 로고
    • Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
    • Lin Y., Devin A., Rodriguez Y., Liu Z.G. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev. 1999, 13:2514-2526.
    • (1999) Genes Dev. , vol.13 , pp. 2514-2526
    • Lin, Y.1    Devin, A.2    Rodriguez, Y.3    Liu, Z.G.4
  • 164
    • 0033812557 scopus 로고    scopus 로고
    • Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis
    • Lin Y., Ma W., Benchimol S. Pidd, a new death-domain-containing protein, is induced by p53 and promotes apoptosis. Nat. Genet. 2000, 26:122-127.
    • (2000) Nat. Genet. , vol.26 , pp. 122-127
    • Lin, Y.1    Ma, W.2    Benchimol, S.3
  • 166
    • 84859299752 scopus 로고    scopus 로고
    • Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury
    • Linkermann A., Brasen J.H., Himmerkus N., Liu S., Huber T.B., Kunzendorf U., Krautwald S. Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury. Kidney Int. 2012, 81:751-761.
    • (2012) Kidney Int. , vol.81 , pp. 751-761
    • Linkermann, A.1    Brasen, J.H.2    Himmerkus, N.3    Liu, S.4    Huber, T.B.5    Kunzendorf, U.6    Krautwald, S.7
  • 167
    • 33645056953 scopus 로고    scopus 로고
    • Caspase inhibitors: a pharmaceutical industry perspective
    • Linton S.D. Caspase inhibitors: a pharmaceutical industry perspective. Curr. Top Med. Chem. 2005, 5:1697-1717.
    • (2005) Curr. Top Med. Chem. , vol.5 , pp. 1697-1717
    • Linton, S.D.1
  • 168
    • 0014575182 scopus 로고
    • Programmed cell death. Activation of lysis by a mechanism involving the synthesis of protein
    • Lockshin R.A. Programmed cell death. Activation of lysis by a mechanism involving the synthesis of protein. J.Insect Physiol. 1969, 15:1505-1516.
    • (1969) J.Insect Physiol. , vol.15 , pp. 1505-1516
    • Lockshin, R.A.1
  • 169
    • 0001139444 scopus 로고
    • Programmed cell Death-I. Cytology of degeneration in the intersegmental muscles of the Pernyi Silkmoth
    • Lockshin R.A., Williams C.M. Programmed cell Death-I. Cytology of degeneration in the intersegmental muscles of the Pernyi Silkmoth. J.Insect Physiol. 1965, 11:123-133.
    • (1965) J.Insect Physiol. , vol.11 , pp. 123-133
    • Lockshin, R.A.1    Williams, C.M.2
  • 170
    • 17144376810 scopus 로고    scopus 로고
    • High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal
    • Lotze M.T., Tracey K.J. High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal. Nat. Rev. Immunol. 2005, 5:331-342.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 331-342
    • Lotze, M.T.1    Tracey, K.J.2
  • 171
    • 57149135309 scopus 로고    scopus 로고
    • Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax
    • Lovell J.F., Billen L.P., Bindner S., Shamas-Din A., Fradin C., Leber B., Andrews D.W. Membrane binding by tBid initiates an ordered series of events culminating in membrane permeabilization by Bax. Cell 2008, 135:1074-1084.
    • (2008) Cell , vol.135 , pp. 1074-1084
    • Lovell, J.F.1    Billen, L.P.2    Bindner, S.3    Shamas-Din, A.4    Fradin, C.5    Leber, B.6    Andrews, D.W.7
  • 173
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo X., Budihardjo I., Zou H., Slaughter C., Wang X. Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 1998, 94:481-490.
    • (1998) Cell , vol.94 , pp. 481-490
    • Luo, X.1    Budihardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 174
    • 0014324817 scopus 로고
    • Experimental retinal detachment in the owl monkey. I. Methods of producation and clinical picture
    • Machemer R., Norton E.W. Experimental retinal detachment in the owl monkey. I. Methods of producation and clinical picture. Am. J. Ophthalmol. 1968, 66:388-396.
    • (1968) Am. J. Ophthalmol. , vol.66 , pp. 388-396
    • Machemer, R.1    Norton, E.W.2
  • 176
    • 0015069387 scopus 로고
    • Evidence for induction by cortisol invitro of a protein inhibitor of transport and phosphorylation processes in rat thymocytes
    • Makman M.H., Dvorkin B., White A. Evidence for induction by cortisol invitro of a protein inhibitor of transport and phosphorylation processes in rat thymocytes. Proc. Natl. Acad. Sci. U. S. A. 1971, 68:1269-1273.
    • (1971) Proc. Natl. Acad. Sci. U. S. A. , vol.68 , pp. 1269-1273
    • Makman, M.H.1    Dvorkin, B.2    White, A.3
  • 177
    • 84859562694 scopus 로고    scopus 로고
    • Targeting autophagy addiction in cancer
    • Mancias J.D., Kimmelman A.C. Targeting autophagy addiction in cancer. Oncotarget 2011, 2:1302-1306.
    • (2011) Oncotarget , vol.2 , pp. 1302-1306
    • Mancias, J.D.1    Kimmelman, A.C.2
  • 178
    • 34547132328 scopus 로고    scopus 로고
    • Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3
    • Marino G., Salvador-Montoliu N., Fueyo A., Knecht E., Mizushima N., Lopez-Otin C. Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3. J.Biol. Chem. 2007, 282:18573-18583.
    • (2007) J.Biol. Chem. , vol.282 , pp. 18573-18583
    • Marino, G.1    Salvador-Montoliu, N.2    Fueyo, A.3    Knecht, E.4    Mizushima, N.5    Lopez-Otin, C.6
  • 181
    • 34447302293 scopus 로고    scopus 로고
    • ACritical role for Bim in retinal ganglion cell death
    • McKernan D.P., Cotter T.G. ACritical role for Bim in retinal ganglion cell death. J.Neurochem. 2007, 102:922-930.
    • (2007) J.Neurochem. , vol.102 , pp. 922-930
    • McKernan, D.P.1    Cotter, T.G.2
  • 183
    • 0041853690 scopus 로고    scopus 로고
    • Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
    • Micheau O., Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 2003, 114:181-190.
    • (2003) Cell , vol.114 , pp. 181-190
    • Micheau, O.1    Tschopp, J.2
  • 187
    • 0027449187 scopus 로고
    • Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C.elegans cell death gene ced-3
    • Miura M., Zhu H., Rotello R., Hartwieg E.A., Yuan J. Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C.elegans cell death gene ced-3. Cell 1993, 75:653-660.
    • (1993) Cell , vol.75 , pp. 653-660
    • Miura, M.1    Zhu, H.2    Rotello, R.3    Hartwieg, E.A.4    Yuan, J.5
  • 189
    • 77955844798 scopus 로고    scopus 로고
    • Activation of mitochondrial calpain and release of apoptosis-inducing factor from mitochondria in RCS rat retinal degeneration
    • Mizukoshi S., Nakazawa M., Sato K., Ozaki T., Metoki T., Ishiguro S. Activation of mitochondrial calpain and release of apoptosis-inducing factor from mitochondria in RCS rat retinal degeneration. Exp. Eye Res. 2010, 91:353-361.
    • (2010) Exp. Eye Res. , vol.91 , pp. 353-361
    • Mizukoshi, S.1    Nakazawa, M.2    Sato, K.3    Ozaki, T.4    Metoki, T.5    Ishiguro, S.6
  • 190
    • 77956416339 scopus 로고    scopus 로고
    • Autophagy in mammalian development and differentiation
    • Mizushima N., Levine B. Autophagy in mammalian development and differentiation. Nat. Cell Biol. 2010, 12:823-830.
    • (2010) Nat. Cell Biol. , vol.12 , pp. 823-830
    • Mizushima, N.1    Levine, B.2
  • 192
    • 39849109338 scopus 로고    scopus 로고
    • Autophagy fights disease through cellular self-digestion
    • Mizushima N., Levine B., Cuervo A.M., Klionsky D.J. Autophagy fights disease through cellular self-digestion. Nature 2008, 451:1069-1075.
    • (2008) Nature , vol.451 , pp. 1069-1075
    • Mizushima, N.1    Levine, B.2    Cuervo, A.M.3    Klionsky, D.J.4
  • 193
    • 75749122303 scopus 로고    scopus 로고
    • Methods in mammalian autophagy research
    • Mizushima N., Yoshimori T., Levine B. Methods in mammalian autophagy research. Cell 2010, 140:313-326.
    • (2010) Cell , vol.140 , pp. 313-326
    • Mizushima, N.1    Yoshimori, T.2    Levine, B.3
  • 195
    • 70349238897 scopus 로고    scopus 로고
    • Membrane-bound Fas ligand requires RIP1 for efficient activation of caspase-8 within the death-inducing signaling complex
    • Morgan M.J., Kim Y.S., Liu Z.G. Membrane-bound Fas ligand requires RIP1 for efficient activation of caspase-8 within the death-inducing signaling complex. J.Immunol. 2009, 183:3278-3284.
    • (2009) J.Immunol. , vol.183 , pp. 3278-3284
    • Morgan, M.J.1    Kim, Y.S.2    Liu, Z.G.3
  • 196
    • 0031828871 scopus 로고    scopus 로고
    • Suppression of developmental retinal cell death but not of photoreceptor degeneration in Bax-deficient mice
    • Mosinger Ogilvie J., Deckwerth T.L., Knudson C.M., Korsmeyer S.J. Suppression of developmental retinal cell death but not of photoreceptor degeneration in Bax-deficient mice. Invest. Ophthalmol. Vis. Sci. 1998, 39:1713-1720.
    • (1998) Invest. Ophthalmol. Vis. Sci. , vol.39 , pp. 1713-1720
    • Mosinger Ogilvie, J.1    Deckwerth, T.L.2    Knudson, C.M.3    Korsmeyer, S.J.4
  • 197
    • 34347344991 scopus 로고    scopus 로고
    • Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis
    • Moubarak R.S., Yuste V.J., Artus C., Bouharrour A., Greer P.A., Menissier-de Murcia J., Susin S.A. Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis. Mol. Cell Biol. 2007, 27:4844-4862.
    • (2007) Mol. Cell Biol. , vol.27 , pp. 4844-4862
    • Moubarak, R.S.1    Yuste, V.J.2    Artus, C.3    Bouharrour, A.4    Greer, P.A.5    Menissier-de Murcia, J.6    Susin, S.A.7
  • 199
    • 55349146967 scopus 로고    scopus 로고
    • Inhibition of nuclear translocation of apoptosis-inducing factor is an essential mechanism of the neuroprotective activity of pigment epithelium-derived factor in a rat model of retinal degeneration
    • Murakami Y., Ikeda Y., Yonemitsu Y., Onimaru M., Nakagawa K., Kohno R., Miyazaki M., Hisatomi T., Nakamura M., Yabe T., Hasegawa M., Ishibashi T., Sueishi K. Inhibition of nuclear translocation of apoptosis-inducing factor is an essential mechanism of the neuroprotective activity of pigment epithelium-derived factor in a rat model of retinal degeneration. Am. J. Pathol. 2008, 173:1326-1338.
    • (2008) Am. J. Pathol. , vol.173 , pp. 1326-1338
    • Murakami, Y.1    Ikeda, Y.2    Yonemitsu, Y.3    Onimaru, M.4    Nakagawa, K.5    Kohno, R.6    Miyazaki, M.7    Hisatomi, T.8    Nakamura, M.9    Yabe, T.10    Hasegawa, M.11    Ishibashi, T.12    Sueishi, K.13
  • 204
    • 77649152255 scopus 로고    scopus 로고
    • Autoimmunity and the clearance of dead cells
    • Nagata S., Hanayama R., Kawane K. Autoimmunity and the clearance of dead cells. Cell 2010, 140:619-630.
    • (2010) Cell , vol.140 , pp. 619-630
    • Nagata, S.1    Hanayama, R.2    Kawane, K.3
  • 206
    • 20444390503 scopus 로고    scopus 로고
    • Crystallin distribution in Bruch's membrane-choroid complex from AMD and age-matched donor eyes
    • Nakata K., Crabb J.W., Hollyfield J.G. Crystallin distribution in Bruch's membrane-choroid complex from AMD and age-matched donor eyes. Exp. Eye Res. 2005, 80:821-826.
    • (2005) Exp. Eye Res. , vol.80 , pp. 821-826
    • Nakata, K.1    Crabb, J.W.2    Hollyfield, J.G.3
  • 210
    • 77950365906 scopus 로고    scopus 로고
    • Nonresolving inflammation
    • Nathan C., Ding A. Nonresolving inflammation. Cell 2010, 140:871-882.
    • (2010) Cell , vol.140 , pp. 871-882
    • Nathan, C.1    Ding, A.2
  • 211
    • 0842304221 scopus 로고    scopus 로고
    • Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4
    • Newton K., Sun X., Dixit V.M. Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4. Mol. Cell Biol. 2004, 24:1464-1469.
    • (2004) Mol. Cell Biol. , vol.24 , pp. 1464-1469
    • Newton, K.1    Sun, X.2    Dixit, V.M.3
  • 212
    • 76049095102 scopus 로고    scopus 로고
    • Oxidative modification sensitizes mitochondrial apoptosis-inducing factor to calpain-mediated processing
    • Norberg E., Gogvadze V., Vakifahmetoglu H., Orrenius S., Zhivotovsky B. Oxidative modification sensitizes mitochondrial apoptosis-inducing factor to calpain-mediated processing. Free Radic. Biol. Med. 2010, 48:791-797.
    • (2010) Free Radic. Biol. Med. , vol.48 , pp. 791-797
    • Norberg, E.1    Gogvadze, V.2    Vakifahmetoglu, H.3    Orrenius, S.4    Zhivotovsky, B.5
  • 217
    • 0035286734 scopus 로고    scopus 로고
    • Molecular dissection of autophagy: two ubiquitin-like systems
    • Ohsumi Y. Molecular dissection of autophagy: two ubiquitin-like systems. Nat. Rev. Mol. Cell Biol. 2001, 2:211-216.
    • (2001) Nat. Rev. Mol. Cell Biol. , vol.2 , pp. 211-216
    • Ohsumi, Y.1
  • 218
    • 17844394478 scopus 로고    scopus 로고
    • Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space
    • Otera H., Ohsakaya S., Nagaura Z., Ishihara N., Mihara K. Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space. Embo J. 2005, 24:1375-1386.
    • (2005) Embo J. , vol.24 , pp. 1375-1386
    • Otera, H.1    Ohsakaya, S.2    Nagaura, Z.3    Ishihara, N.4    Mihara, K.5
  • 219
    • 84865339319 scopus 로고    scopus 로고
    • Intravitreal injection or topical eye-drop application of a mu-calpain C2L domain peptide protects against photoreceptor cell death in Royal College of Surgeons' rats, a model of retinitis pigmentosa
    • Ozaki T., Nakazawa M., Yamashita T., Sorimachi H., Hata S., Tomita H., Isago H., Baba A., Ishiguro S. Intravitreal injection or topical eye-drop application of a mu-calpain C2L domain peptide protects against photoreceptor cell death in Royal College of Surgeons' rats, a model of retinitis pigmentosa. Biochim. Biophys. Acta 2012, 1822:1783-1795.
    • (2012) Biochim. Biophys. Acta , vol.1822 , pp. 1783-1795
    • Ozaki, T.1    Nakazawa, M.2    Yamashita, T.3    Sorimachi, H.4    Hata, S.5    Tomita, H.6    Isago, H.7    Baba, A.8    Ishiguro, S.9
  • 220
    • 34548847441 scopus 로고    scopus 로고
    • Excessive activation of poly(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse
    • Paquet-Durand F., Silva J., Talukdar T., Johnson L.E., Azadi S., van Veen T., Ueffing M., Hauck S.M., Ekstrom P.A. Excessive activation of poly(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse. J.Neurosci. 2007, 27:10311-10319.
    • (2007) J.Neurosci. , vol.27 , pp. 10311-10319
    • Paquet-Durand, F.1    Silva, J.2    Talukdar, T.3    Johnson, L.E.4    Azadi, S.5    van Veen, T.6    Ueffing, M.7    Hauck, S.M.8    Ekstrom, P.A.9
  • 221
    • 34347224404 scopus 로고    scopus 로고
    • Caspase-dependent apoptosis in light-induced retinal degeneration
    • Perche O., Doly M., Ranchon-Cole I. Caspase-dependent apoptosis in light-induced retinal degeneration. Invest. Ophthalmol. Vis. Sci. 2007, 48:2753-2759.
    • (2007) Invest. Ophthalmol. Vis. Sci. , vol.48 , pp. 2753-2759
    • Perche, O.1    Doly, M.2    Ranchon-Cole, I.3
  • 222
    • 0037276437 scopus 로고    scopus 로고
    • The CD95(APO-1/Fas) DISC and beyond
    • Peter M.E., Krammer P.H. The CD95(APO-1/Fas) DISC and beyond. Cell Death Differ. 2003, 10:26-35.
    • (2003) Cell Death Differ. , vol.10 , pp. 26-35
    • Peter, M.E.1    Krammer, P.H.2
  • 224
    • 14844328621 scopus 로고    scopus 로고
    • Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria
    • Polster B.M., Basanez G., Etxebarria A., Hardwick J.M., Nicholls D.G. Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria. J.Biol. Chem. 2005, 280:6447-6454.
    • (2005) J.Biol. Chem. , vol.280 , pp. 6447-6454
    • Polster, B.M.1    Basanez, G.2    Etxebarria, A.3    Hardwick, J.M.4    Nicholls, D.G.5
  • 226
    • 58149141478 scopus 로고    scopus 로고
    • Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa
    • Punzo C., Kornacker K., Cepko C.L. Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa. Nat. Neurosci. 2009, 12:44-52.
    • (2009) Nat. Neurosci. , vol.12 , pp. 44-52
    • Punzo, C.1    Kornacker, K.2    Cepko, C.L.3
  • 227
    • 0033104996 scopus 로고    scopus 로고
    • The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex
    • Puthalakath H., Huang D.C., O'Reilly L.A., King S.M., Strasser A. The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex. Mol. Cell 1999, 3:287-296.
    • (1999) Mol. Cell , vol.3 , pp. 287-296
    • Puthalakath, H.1    Huang, D.C.2    O'Reilly, L.A.3    King, S.M.4    Strasser, A.5
  • 228
    • 0035823238 scopus 로고    scopus 로고
    • Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis
    • Puthalakath H., Villunger A., O'Reilly L.A., Beaumont J.G., Coultas L., Cheney R.E., Huang D.C., Strasser A. Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Science 2001, 293:1829-1832.
    • (2001) Science , vol.293 , pp. 1829-1832
    • Puthalakath, H.1    Villunger, A.2    O'Reilly, L.A.3    Beaumont, J.G.4    Coultas, L.5    Cheney, R.E.6    Huang, D.C.7    Strasser, A.8
  • 232
    • 18244410390 scopus 로고    scopus 로고
    • The genomic response to retinal disease and injury: evidence for endothelin signaling from photoreceptors to glia
    • Rattner A., Nathans J. The genomic response to retinal disease and injury: evidence for endothelin signaling from photoreceptors to glia. J.Neurosci. 2005, 25:4540-4549.
    • (2005) J.Neurosci. , vol.25 , pp. 4540-4549
    • Rattner, A.1    Nathans, J.2
  • 234
    • 80755180853 scopus 로고    scopus 로고
    • Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways
    • Ravichandran K.S. Beginnings of a good apoptotic meal: the find-me and eat-me signaling pathways. Immunity 2011, 35:445-455.
    • (2011) Immunity , vol.35 , pp. 445-455
    • Ravichandran, K.S.1
  • 235
    • 0036566266 scopus 로고    scopus 로고
    • Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
    • Ravikumar B., Duden R., Rubinsztein D.C. Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy. Hum. Mol. Gen. 2002, 11:1107-1117.
    • (2002) Hum. Mol. Gen. , vol.11 , pp. 1107-1117
    • Ravikumar, B.1    Duden, R.2    Rubinsztein, D.C.3
  • 237
    • 79953797118 scopus 로고    scopus 로고
    • Histopathological and neurological features of Atg4b knockout mice
    • Read R., Savelieva K., Baker K., Hansen G., Vogel P. Histopathological and neurological features of Atg4b knockout mice. Vet. Pathol. 2011, 48:486-494.
    • (2011) Vet. Pathol. , vol.48 , pp. 486-494
    • Read, R.1    Savelieva, K.2    Baker, K.3    Hansen, G.4    Vogel, P.5
  • 238
    • 0042477717 scopus 로고    scopus 로고
    • Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway
    • Reimertz C., Kogel D., Rami A., Chittenden T., Prehn J.H. Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J.Cell Biol. 2003, 162:587-597.
    • (2003) J.Cell Biol. , vol.162 , pp. 587-597
    • Reimertz, C.1    Kogel, D.2    Rami, A.3    Chittenden, T.4    Prehn, J.H.5
  • 239
    • 0017529312 scopus 로고
    • Autography in visual cells and pigment epithelium
    • Reme C.E. Autography in visual cells and pigment epithelium. Invest. Ophthalmol. Vis. Sci. 1977, 16:807-814.
    • (1977) Invest. Ophthalmol. Vis. Sci. , vol.16 , pp. 807-814
    • Reme, C.E.1
  • 241
    • 0017718492 scopus 로고
    • The effects of hibernation on cone visual cells in the ground squirrel
    • Reme C.E., Young R.W. The effects of hibernation on cone visual cells in the ground squirrel. Invest. Ophthalmol. Vis. Sci. 1977, 16:815-840.
    • (1977) Invest. Ophthalmol. Vis. Sci. , vol.16 , pp. 815-840
    • Reme, C.E.1    Young, R.W.2
  • 243
    • 0032846377 scopus 로고    scopus 로고
    • Photoreceptor autophagy: effects of light history on number and opsin content of degradative vacuoles
    • Reme C.E., Wolfrum U., Imsand C., Hafezi F., Williams T.P. Photoreceptor autophagy: effects of light history on number and opsin content of degradative vacuoles. Invest. Ophthalmol. Vis. Sci. 1999, 40:2398-2404.
    • (1999) Invest. Ophthalmol. Vis. Sci. , vol.40 , pp. 2398-2404
    • Reme, C.E.1    Wolfrum, U.2    Imsand, C.3    Hafezi, F.4    Williams, T.P.5
  • 244
    • 77955901392 scopus 로고    scopus 로고
    • Chemokine levels in subretinal fluid obtained during scleral buckling surgery after rhegmatogenous retinal detachment
    • Ricker L.J., Kijlstra A., de Jager W., Liem A.T., Hendrikse F., La Heij E.C. Chemokine levels in subretinal fluid obtained during scleral buckling surgery after rhegmatogenous retinal detachment. Invest. Ophthalmol. Vis. Sci. 2010, 51:4143-4150.
    • (2010) Invest. Ophthalmol. Vis. Sci. , vol.51 , pp. 4143-4150
    • Ricker, L.J.1    Kijlstra, A.2    de Jager, W.3    Liem, A.T.4    Hendrikse, F.5    La Heij, E.C.6
  • 246
    • 77952059124 scopus 로고    scopus 로고
    • Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model
    • Rosenbaum D.M., Degterev A., David J., Rosenbaum P.S., Roth S., Grotta J.C., Cuny G.D., Yuan J., Savitz S.I. Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model. J.Neurosci. Res. 2010, 88:1569-1576.
    • (2010) J.Neurosci. Res. , vol.88 , pp. 1569-1576
    • Rosenbaum, D.M.1    Degterev, A.2    David, J.3    Rosenbaum, P.S.4    Roth, S.5    Grotta, J.C.6    Cuny, G.D.7    Yuan, J.8    Savitz, S.I.9
  • 247
    • 84876699484 scopus 로고    scopus 로고
    • Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury
    • Roychowdhury S., McMullen M.R., Pisano S.G., Liu X., Nagy L.E. Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury. Hepatology 2012, 57:1773-1783.
    • (2012) Hepatology , vol.57 , pp. 1773-1783
    • Roychowdhury, S.1    McMullen, M.R.2    Pisano, S.G.3    Liu, X.4    Nagy, L.E.5
  • 249
    • 33751239138 scopus 로고    scopus 로고
    • Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors
    • Sanges D., Comitato A., Tammaro R., Marigo V. Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:17366-17371.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 17366-17371
    • Sanges, D.1    Comitato, A.2    Tammaro, R.3    Marigo, V.4
  • 251
    • 0014006159 scopus 로고
    • Death in embryonic systems
    • Saunders J.W. Death in embryonic systems. Science 1966, 154:604-612.
    • (1966) Science , vol.154 , pp. 604-612
    • Saunders, J.W.1
  • 252
    • 0033556310 scopus 로고    scopus 로고
    • The role of c-FLIP in modulation of CD95-induced apoptosis
    • Scaffidi C., Schmitz I., Krammer P.H., Peter M.E. The role of c-FLIP in modulation of CD95-induced apoptosis. J.Biol. Chem. 1999, 274:1541-1548.
    • (1999) J.Biol. Chem. , vol.274 , pp. 1541-1548
    • Scaffidi, C.1    Schmitz, I.2    Krammer, P.H.3    Peter, M.E.4
  • 253
    • 0037062934 scopus 로고    scopus 로고
    • Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
    • Scaffidi P., Misteli T., Bianchi M.E. Release of chromatin protein HMGB1 by necrotic cells triggers inflammation. Nature 2002, 418:191-195.
    • (2002) Nature , vol.418 , pp. 191-195
    • Scaffidi, P.1    Misteli, T.2    Bianchi, M.E.3
  • 256
    • 0015880897 scopus 로고
    • The morphology of various types of cell death in prenatal tissues
    • Schweichel J.U., Merker H.J. The morphology of various types of cell death in prenatal tissues. Teratology 1973, 7:253-266.
    • (1973) Teratology , vol.7 , pp. 253-266
    • Schweichel, J.U.1    Merker, H.J.2
  • 257
    • 0018746575 scopus 로고
    • Glucagon-induced autophagy and proteolysis in rat liver: mediation by selective deprivation of intracellular amino acids
    • Schworer C.M., Mortimore G.E. Glucagon-induced autophagy and proteolysis in rat liver: mediation by selective deprivation of intracellular amino acids. Proc. Natl. Acad. Sci. U. S. A. 1979, 76:3169-3173.
    • (1979) Proc. Natl. Acad. Sci. U. S. A. , vol.76 , pp. 3169-3173
    • Schworer, C.M.1    Mortimore, G.E.2
  • 258
    • 0005677775 scopus 로고
    • 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes
    • Seglen P.O., Gordon P.B. 3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes. Proc. Natl. Acad. Sci. U. S. A. 1982, 79:1889-1892.
    • (1982) Proc. Natl. Acad. Sci. U. S. A. , vol.79 , pp. 1889-1892
    • Seglen, P.O.1    Gordon, P.B.2
  • 259
    • 77649225756 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes
    • Shembade N., Ma A., Harhaj E.W. Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes. Science 2010, 327:1135-1139.
    • (2010) Science , vol.327 , pp. 1135-1139
    • Shembade, N.1    Ma, A.2    Harhaj, E.W.3
  • 260
    • 77950591438 scopus 로고    scopus 로고
    • Clinical trial: the efficacy and safety of oral PF-03491390, a pancaspase inhibitor - a randomized placebo-controlled study in patients with chronic hepatitis C
    • Shiffman M.L., Pockros P., McHutchison J.G., Schiff E.R., Morris M., Burgess G. Clinical trial: the efficacy and safety of oral PF-03491390, a pancaspase inhibitor - a randomized placebo-controlled study in patients with chronic hepatitis C. Aliment Pharmacol. Ther. 2010, 31:969-978.
    • (2010) Aliment Pharmacol. Ther. , vol.31 , pp. 969-978
    • Shiffman, M.L.1    Pockros, P.2    McHutchison, J.G.3    Schiff, E.R.4    Morris, M.5    Burgess, G.6
  • 261
    • 0035852747 scopus 로고    scopus 로고
    • Inhibition of the visual cycle invivo by 13-cis retinoic acid protects from light damage and provides a mechanism for night blindness in isotretinoin therapy
    • Sieving P.A., Chaudhry P., Kondo M., Provenzano M., Wu D., Carlson T.J., Bush R.A., Thompson D.A. Inhibition of the visual cycle invivo by 13-cis retinoic acid protects from light damage and provides a mechanism for night blindness in isotretinoin therapy. Proc. Natl. Acad. Sci. U. S. A. 2001, 98:1835-1840.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 1835-1840
    • Sieving, P.A.1    Chaudhry, P.2    Kondo, M.3    Provenzano, M.4    Wu, D.5    Carlson, T.J.6    Bush, R.A.7    Thompson, D.A.8
  • 262
    • 33645115547 scopus 로고    scopus 로고
    • Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial
    • Sotelo J., Briceno E., Lopez-Gonzalez M.A. Adding chloroquine to conventional treatment for glioblastoma multiforme: a randomized, double-blind, placebo-controlled trial. Ann. Inter. Med. 2006, 144:337-343.
    • (2006) Ann. Inter. Med. , vol.144 , pp. 337-343
    • Sotelo, J.1    Briceno, E.2    Lopez-Gonzalez, M.A.3
  • 263
    • 0029054725 scopus 로고
    • RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death
    • Stanger B.Z., Leder P., Lee T.H., Kim E., Seed B. RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. Cell 1995, 81:513-523.
    • (1995) Cell , vol.81 , pp. 513-523
    • Stanger, B.Z.1    Leder, P.2    Lee, T.H.3    Kim, E.4    Seed, B.5
  • 264
    • 44949106317 scopus 로고    scopus 로고
    • Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species
    • Sumimoto H. Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species. FEBS J. 2008, 275:3249-3277.
    • (2008) FEBS J. , vol.275 , pp. 3249-3277
    • Sumimoto, H.1
  • 266
    • 0037088632 scopus 로고    scopus 로고
    • Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3
    • Sun X., Yin J., Starovasnik M.A., Fairbrother W.J., Dixit V.M. Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3. J.Biol. Chem. 2002, 277:9505-9511.
    • (2002) J.Biol. Chem. , vol.277 , pp. 9505-9511
    • Sun, X.1    Yin, J.2    Starovasnik, M.A.3    Fairbrother, W.J.4    Dixit, V.M.5
  • 267
    • 84862907788 scopus 로고    scopus 로고
    • Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
    • Sun L., Wang H., Wang Z., He S., Chen S., Liao D., Wang L., Yan J., Liu W., Lei X., Wang X. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. Cell 2012, 148:213-227.
    • (2012) Cell , vol.148 , pp. 213-227
    • Sun, L.1    Wang, H.2    Wang, Z.3    He, S.4    Chen, S.5    Liao, D.6    Wang, L.7    Yan, J.8    Liu, W.9    Lei, X.10    Wang, X.11
  • 269
    • 0033713002 scopus 로고    scopus 로고
    • Structure of Bax: coregulation of dimer formation and intracellular localization
    • Suzuki M., Youle R.J., Tjandra N. Structure of Bax: coregulation of dimer formation and intracellular localization. Cell 2000, 103:645-654.
    • (2000) Cell , vol.103 , pp. 645-654
    • Suzuki, M.1    Youle, R.J.2    Tjandra, N.3
  • 271
    • 0017762737 scopus 로고
    • Retinal ultrastructure in advanced retinitis pigmentosa
    • Szamier R.B., Berson E.L. Retinal ultrastructure in advanced retinitis pigmentosa. Invest. Ophthalmol. Vis. Sci. 1977, 16:947-962.
    • (1977) Invest. Ophthalmol. Vis. Sci. , vol.16 , pp. 947-962
    • Szamier, R.B.1    Berson, E.L.2
  • 272
    • 77956095537 scopus 로고    scopus 로고
    • Mitochondria and cell death: outer membrane permeabilization and beyond
    • Tait S.W., Green D.R. Mitochondria and cell death: outer membrane permeabilization and beyond. Nat. Rev. Mol Cell. Biol. 2010, 11:621-632.
    • (2010) Nat. Rev. Mol Cell. Biol. , vol.11 , pp. 621-632
    • Tait, S.W.1    Green, D.R.2
  • 274
    • 34548169402 scopus 로고    scopus 로고
    • Dark rearing rescues P23H rhodopsin-induced retinal degeneration in a transgenic Xenopus laevis model of retinitis pigmentosa: a chromophore-dependent mechanism characterized by production of N-terminally truncated mutant rhodopsin
    • Tam B.M., Moritz O.L. Dark rearing rescues P23H rhodopsin-induced retinal degeneration in a transgenic Xenopus laevis model of retinitis pigmentosa: a chromophore-dependent mechanism characterized by production of N-terminally truncated mutant rhodopsin. J. Neurosci. 2007, 27:9043-9053.
    • (2007) J. Neurosci. , vol.27 , pp. 9043-9053
    • Tam, B.M.1    Moritz, O.L.2
  • 275
    • 33746108329 scopus 로고    scopus 로고
    • Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy
    • Tanida I., Minematsu-Ikeguchi N., Ueno T., Kominami E. Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy. Autophagy 2005, 1:84-91.
    • (2005) Autophagy , vol.1 , pp. 84-91
    • Tanida, I.1    Minematsu-Ikeguchi, N.2    Ueno, T.3    Kominami, E.4
  • 277
    • 0013879272 scopus 로고
    • Requirement for RNA and protein synthesis for induced regression of the tadpole tail in organ culture
    • Tata J.R. Requirement for RNA and protein synthesis for induced regression of the tadpole tail in organ culture. Dev. Biol. 1966, 13:77-94.
    • (1966) Dev. Biol. , vol.13 , pp. 77-94
    • Tata, J.R.1
  • 282
    • 2442453730 scopus 로고    scopus 로고
    • The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress
    • Tinel A., Tschopp J. The PIDDosome, a protein complex implicated in activation of caspase-2 in response to genotoxic stress. Science 2004, 304:843-846.
    • (2004) Science , vol.304 , pp. 843-846
    • Tinel, A.1    Tschopp, J.2
  • 283
    • 84865293299 scopus 로고    scopus 로고
    • Autophagy inhibition in cancer therapy: metabolic considerations for antitumor immunity
    • Townsend K.N., Hughson L.R., Schlie K., Poon V.I., Westerback A., Lum J.J. Autophagy inhibition in cancer therapy: metabolic considerations for antitumor immunity. Immunol. Rev. 2012, 249:176-194.
    • (2012) Immunol. Rev. , vol.249 , pp. 176-194
    • Townsend, K.N.1    Hughson, L.R.2    Schlie, K.3    Poon, V.I.4    Westerback, A.5    Lum, J.J.6
  • 285
    • 0042467558 scopus 로고    scopus 로고
    • CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members
    • Trompouki E., Hatzivassiliou E., Tsichritzis T., Farmer H., Ashworth A., Mosialos G. CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members. Nature 2003, 424:793-796.
    • (2003) Nature , vol.424 , pp. 793-796
    • Trompouki, E.1    Hatzivassiliou, E.2    Tsichritzis, T.3    Farmer, H.4    Ashworth, A.5    Mosialos, G.6
  • 286
    • 0021821903 scopus 로고
    • Involvement of the bcl-2 gene in human follicular lymphoma
    • Tsujimoto Y., Cossman J., Jaffe E., Croce C.M. Involvement of the bcl-2 gene in human follicular lymphoma. Science 1985, 228:1440-1443.
    • (1985) Science , vol.228 , pp. 1440-1443
    • Tsujimoto, Y.1    Cossman, J.2    Jaffe, E.3    Croce, C.M.4
  • 287
    • 0027424777 scopus 로고
    • Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
    • Tsukada M., Ohsumi Y. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett. 1993, 333:169-174.
    • (1993) FEBS Lett. , vol.333 , pp. 169-174
    • Tsukada, M.1    Ohsumi, Y.2
  • 288
    • 33947230031 scopus 로고    scopus 로고
    • Identification of prothymosin-alpha1, the necrosis-apoptosis switch molecule in cortical neuronal cultures
    • Ueda H., Fujita R., Yoshida A., Matsunaga H., Ueda M. Identification of prothymosin-alpha1, the necrosis-apoptosis switch molecule in cortical neuronal cultures. J.Cell Biol. 2007, 176:853-862.
    • (2007) J.Cell Biol. , vol.176 , pp. 853-862
    • Ueda, H.1    Fujita, R.2    Yoshida, A.3    Matsunaga, H.4    Ueda, M.5
  • 289
    • 75849147620 scopus 로고    scopus 로고
    • Preconditioning-induced protection of photoreceptors requires activation of the signal-transducing receptor gp130 in photoreceptors
    • Ueki Y., Le Y.Z., Chollangi S., Muller W., Ash J.D. Preconditioning-induced protection of photoreceptors requires activation of the signal-transducing receptor gp130 in photoreceptors. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:21389-21394.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 21389-21394
    • Ueki, Y.1    Le, Y.Z.2    Chollangi, S.3    Muller, W.4    Ash, J.D.5
  • 290
    • 47749133767 scopus 로고    scopus 로고
    • Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1
    • Upton J.W., Kaiser W.J., Mocarski E.S. Cytomegalovirus M45 cell death suppression requires receptor-interacting protein (RIP) homotypic interaction motif (RHIM)-dependent interaction with RIP1. J.Biol. Chem. 2008, 283:16966-16970.
    • (2008) J.Biol. Chem. , vol.283 , pp. 16966-16970
    • Upton, J.W.1    Kaiser, W.J.2    Mocarski, E.S.3
  • 293
    • 0141996262 scopus 로고    scopus 로고
    • First clinical trial of a novel caspase inhibitor: anti-apoptotic caspase inhibitor, IDN-6556, improves liver enzymes
    • Valentino K.L., Gutierrez M., Sanchez R., Winship M.J., Shapiro D.A. First clinical trial of a novel caspase inhibitor: anti-apoptotic caspase inhibitor, IDN-6556, improves liver enzymes. Int. J. Clin. Pharmacol. Ther. 2003, 41:441-449.
    • (2003) Int. J. Clin. Pharmacol. Ther. , vol.41 , pp. 441-449
    • Valentino, K.L.1    Gutierrez, M.2    Sanchez, R.3    Winship, M.J.4    Shapiro, D.A.5
  • 294
    • 82755198022 scopus 로고    scopus 로고
    • Proliferative versus apoptotic functions of caspase-8 Hetero or homo: the caspase-8 dimer controls cell fate
    • van Raam B.J., Salvesen G.S. Proliferative versus apoptotic functions of caspase-8 Hetero or homo: the caspase-8 dimer controls cell fate. Biochim. Biophys. Acta 2012, 1824:113-122.
    • (2012) Biochim. Biophys. Acta , vol.1824 , pp. 113-122
    • van Raam, B.J.1    Salvesen, G.S.2
  • 299
    • 0023786047 scopus 로고
    • Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells
    • Vaux D.L., Cory S., Adams J.M. Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells. Nature 1988, 335:440-442.
    • (1988) Nature , vol.335 , pp. 440-442
    • Vaux, D.L.1    Cory, S.2    Adams, J.M.3
  • 304
    • 61349131972 scopus 로고    scopus 로고
    • Foveal microstructure and visual acuity after retinal detachment repair: imaging analysis by Fourier-domain optical coherence tomography
    • Wakabayashi T., Oshima Y., Fujimoto H., Murakami Y., Sakaguchi H., Kusaka S., Tano Y. Foveal microstructure and visual acuity after retinal detachment repair: imaging analysis by Fourier-domain optical coherence tomography. Ophthalmology 2009, 116:519-528.
    • (2009) Ophthalmology , vol.116 , pp. 519-528
    • Wakabayashi, T.1    Oshima, Y.2    Fujimoto, H.3    Murakami, Y.4    Sakaguchi, H.5    Kusaka, S.6    Tano, Y.7
  • 305
    • 0032508414 scopus 로고    scopus 로고
    • NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang C.Y., Mayo M.W., Korneluk R.G., Goeddel D.V., Baldwin A.S. NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 1998, 281:1680-1683.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin, A.S.5
  • 307
    • 58349109733 scopus 로고    scopus 로고
    • Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and age-related macular degeneration
    • Wang A.L., Lukas T.J., Yuan M., Du N., Tso M.O., Neufeld A.H. Autophagy and exosomes in the aged retinal pigment epithelium: possible relevance to drusen formation and age-related macular degeneration. PLoS One 2009, 4:e4160.
    • (2009) PLoS One , vol.4
    • Wang, A.L.1    Lukas, T.J.2    Yuan, M.3    Du, N.4    Tso, M.O.5    Neufeld, A.H.6
  • 308
    • 69949180640 scopus 로고    scopus 로고
    • TOR-mediated autophagy regulates cell death in Drosophila neurodegenerative disease
    • Wang T., Lao U., Edgar B.A. TOR-mediated autophagy regulates cell death in Drosophila neurodegenerative disease. J.Cell Biol. 2009, 186:703-711.
    • (2009) J.Cell Biol. , vol.186 , pp. 703-711
    • Wang, T.1    Lao, U.2    Edgar, B.A.3
  • 309
    • 84862909353 scopus 로고    scopus 로고
    • The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways
    • Wang Z., Jiang H., Chen S., Du F., Wang X. The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. Cell 2012, 148:228-243.
    • (2012) Cell , vol.148 , pp. 228-243
    • Wang, Z.1    Jiang, H.2    Chen, S.3    Du, F.4    Wang, X.5
  • 312
    • 11144273817 scopus 로고    scopus 로고
    • Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration
    • Wenzel A., Grimm C., Samardzija M., Reme C.E. Molecular mechanisms of light-induced photoreceptor apoptosis and neuroprotection for retinal degeneration. Prog. Retin Eye Res. 2005, 24:275-306.
    • (2005) Prog. Retin Eye Res. , vol.24 , pp. 275-306
    • Wenzel, A.1    Grimm, C.2    Samardzija, M.3    Reme, C.E.4
  • 316
    • 7244245454 scopus 로고    scopus 로고
    • Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis
    • Wright K.M., Linhoff M.W., Potts P.R., Deshmukh M. Decreased apoptosome activity with neuronal differentiation sets the threshold for strict IAP regulation of apoptosis. J.Cell Biol. 2004, 167:303-313.
    • (2004) J.Cell Biol. , vol.167 , pp. 303-313
    • Wright, K.M.1    Linhoff, M.W.2    Potts, P.R.3    Deshmukh, M.4
  • 317
    • 35548974703 scopus 로고    scopus 로고
    • Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD
    • Wright A., Reiley W.W., Chang M., Jin W., Lee A.J., Zhang M., Sun S.C. Regulation of early wave of germ cell apoptosis and spermatogenesis by deubiquitinating enzyme CYLD. Dev. Cell 2007, 13:705-716.
    • (2007) Dev. Cell , vol.13 , pp. 705-716
    • Wright, A.1    Reiley, W.W.2    Chang, M.3    Jin, W.4    Lee, A.J.5    Zhang, M.6    Sun, S.C.7
  • 318
  • 319
    • 33646827842 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation
    • Xu Y., Huang S., Liu Z.G., Han J. Poly(ADP-ribose) polymerase-1 signaling to mitochondria in necrotic cell death requires RIP1/TRAF2-mediated JNK1 activation. J.Biol. Chem. 2006, 281:8788-8795.
    • (2006) J.Biol. Chem. , vol.281 , pp. 8788-8795
    • Xu, Y.1    Huang, S.2    Liu, Z.G.3    Han, J.4
  • 320
    • 0035478060 scopus 로고    scopus 로고
    • Differential expression of apoptotic protease-activating factor-1 and caspase-3 genes and susceptibility to apoptosis during brain development and after traumatic brain injury
    • Yakovlev A.G., Ota K., Wang G., Movsesyan V., Bao W.L., Yoshihara K., Faden A.I. Differential expression of apoptotic protease-activating factor-1 and caspase-3 genes and susceptibility to apoptosis during brain development and after traumatic brain injury. J.Neurosci. 2001, 21:7439-7446.
    • (2001) J.Neurosci. , vol.21 , pp. 7439-7446
    • Yakovlev, A.G.1    Ota, K.2    Wang, G.3    Movsesyan, V.4    Bao, W.L.5    Yoshihara, K.6    Faden, A.I.7
  • 321
    • 0031593675 scopus 로고    scopus 로고
    • Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells
    • Yamamoto A., Tagawa Y., Yoshimori T., Moriyama Y., Masaki R., Tashiro Y. Bafilomycin A1 prevents maturation of autophagic vacuoles by inhibiting fusion between autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E cells. Cell Struct. Func. 1998, 23:33-42.
    • (1998) Cell Struct. Func. , vol.23 , pp. 33-42
    • Yamamoto, A.1    Tagawa, Y.2    Yoshimori, T.3    Moriyama, Y.4    Masaki, R.5    Tashiro, Y.6
  • 323
    • 0942276405 scopus 로고    scopus 로고
    • Preventing retinal detachment-associated photoreceptor cell loss in Bax-deficient mice
    • Yang L., Bula D., Arroyo J.G., Chen D.F. Preventing retinal detachment-associated photoreceptor cell loss in Bax-deficient mice. Invest. Ophthalmol. Vis. Sci. 2004, 45:648-654.
    • (2004) Invest. Ophthalmol. Vis. Sci. , vol.45 , pp. 648-654
    • Yang, L.1    Bula, D.2    Arroyo, J.G.3    Chen, D.F.4
  • 325
    • 34147145520 scopus 로고    scopus 로고
    • Alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress
    • Yaung J., Jin M., Barron E., Spee C., Wawrousek E.F., Kannan R., Hinton D.R. alpha-Crystallin distribution in retinal pigment epithelium and effect of gene knockouts on sensitivity to oxidative stress. Mol. Vis. 2007, 13:566-577.
    • (2007) Mol. Vis. , vol.13 , pp. 566-577
    • Yaung, J.1    Jin, M.2    Barron, E.3    Spee, C.4    Wawrousek, E.F.5    Kannan, R.6    Hinton, D.R.7
  • 326
    • 39149145829 scopus 로고    scopus 로고
    • Exacerbation of retinal degeneration in the absence of alpha crystallins in an invivo model of chemically induced hypoxia
    • Yaung J., Kannan R., Wawrousek E.F., Spee C., Sreekumar P.G., Hinton D.R. Exacerbation of retinal degeneration in the absence of alpha crystallins in an invivo model of chemically induced hypoxia. Exp. Eye Res. 2008, 86:355-365.
    • (2008) Exp. Eye Res. , vol.86 , pp. 355-365
    • Yaung, J.1    Kannan, R.2    Wawrousek, E.F.3    Spee, C.4    Sreekumar, P.G.5    Hinton, D.R.6
  • 334
    • 54249133441 scopus 로고    scopus 로고
    • FLIP and the death effector domain family
    • Yu J.W., Shi Y. FLIP and the death effector domain family. Oncogene 2008, 27:6216-6227.
    • (2008) Oncogene , vol.27 , pp. 6216-6227
    • Yu, J.W.1    Shi, Y.2
  • 339
    • 0027525104 scopus 로고
    • The C.elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme
    • Yuan J., Shaham S., Ledoux S., Ellis H.M., Horvitz H.R. The C.elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell 1993, 75:641-652.
    • (1993) Cell , vol.75 , pp. 641-652
    • Yuan, J.1    Shaham, S.2    Ledoux, S.3    Ellis, H.M.4    Horvitz, H.R.5
  • 341
    • 9444256433 scopus 로고    scopus 로고
    • FAS-mediated apoptosis and its relation to intrinsic pathway activation in an experimental model of retinal detachment
    • Zacks D.N., Zheng Q.D., Han Y., Bakhru R., Miller J.W. FAS-mediated apoptosis and its relation to intrinsic pathway activation in an experimental model of retinal detachment. Invest. Ophthalmol. Vis. Sci. 2004, 45:4563-4569.
    • (2004) Invest. Ophthalmol. Vis. Sci. , vol.45 , pp. 4563-4569
    • Zacks, D.N.1    Zheng, Q.D.2    Han, Y.3    Bakhru, R.4    Miller, J.W.5
  • 342
    • 33645968438 scopus 로고    scopus 로고
    • Activation of signaling pathways and stress-response genes in an experimental model of retinal detachment
    • Zacks D.N., Han Y., Zeng Y., Swaroop A. Activation of signaling pathways and stress-response genes in an experimental model of retinal detachment. Invest. Ophthalmol. Vis. Sci. 2006, 47:1691-1695.
    • (2006) Invest. Ophthalmol. Vis. Sci. , vol.47 , pp. 1691-1695
    • Zacks, D.N.1    Han, Y.2    Zeng, Y.3    Swaroop, A.4
  • 343
    • 35348929461 scopus 로고    scopus 로고
    • Role of the Fas-signaling pathway in photoreceptor neuroprotection
    • Zacks D.N., Boehlke C., Richards A.L., Zheng Q.D. Role of the Fas-signaling pathway in photoreceptor neuroprotection. Arch. Ophthalmol. 2007, 125:1389-1395.
    • (2007) Arch. Ophthalmol. , vol.125 , pp. 1389-1395
    • Zacks, D.N.1    Boehlke, C.2    Richards, A.L.3    Zheng, Q.D.4
  • 344
  • 345
    • 67650812332 scopus 로고    scopus 로고
    • RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
    • Zhang D.W., Shao J., Lin J., Zhang N., Lu B.J., Lin S.C., Dong M.Q., Han J. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 2009, 325:332-336.
    • (2009) Science , vol.325 , pp. 332-336
    • Zhang, D.W.1    Shao, J.2    Lin, J.3    Zhang, N.4    Lu, B.J.5    Lin, S.C.6    Dong, M.Q.7    Han, J.8
  • 346
    • 67650444323 scopus 로고    scopus 로고
    • PUMA promotes Bax translocation by both directly interacting with Bax and by competitive binding to Bcl-X L during UV-induced apoptosis
    • Zhang Y., Xing D., Liu L. PUMA promotes Bax translocation by both directly interacting with Bax and by competitive binding to Bcl-X L during UV-induced apoptosis. Mol. Biol. Cell 2009, 20:3077-3087.
    • (2009) Mol. Biol. Cell , vol.20 , pp. 3077-3087
    • Zhang, Y.1    Xing, D.2    Liu, L.3
  • 347
    • 79952780505 scopus 로고    scopus 로고
    • Functional complementation between FADD and RIP1 in embryos and lymphocytes
    • Zhang H., Zhou X., McQuade T., Li J., Chan F.K., Zhang J. Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature 2011, 471:373-376.
    • (2011) Nature , vol.471 , pp. 373-376
    • Zhang, H.1    Zhou, X.2    McQuade, T.3    Li, J.4    Chan, F.K.5    Zhang, J.6
  • 350
    • 79954525274 scopus 로고    scopus 로고
    • Necrostatin-1 ameliorates symptoms in R6/2 transgenic mouse model of Huntington's disease
    • Zhu S., Zhang Y., Bai G., Li H. Necrostatin-1 ameliorates symptoms in R6/2 transgenic mouse model of Huntington's disease. Cell Death Dis. 2011, 2:e115.
    • (2011) Cell Death Dis. , vol.2
    • Zhu, S.1    Zhang, Y.2    Bai, G.3    Li, H.4
  • 351
    • 77950366886 scopus 로고    scopus 로고
    • Decoding cell death signals in inflammation and immunity
    • Zitvogel L., Kepp O., Kroemer G. Decoding cell death signals in inflammation and immunity. Cell 2010, 140:798-804.
    • (2010) Cell , vol.140 , pp. 798-804
    • Zitvogel, L.1    Kepp, O.2    Kroemer, G.3


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