Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

Science

Volumn 281, Issue 5385, 1998, Pages 2027-2031

  Marzo, Isabel ^a   Brenner, Catherine ^a,b   Zamzami, Naoufal ^a   Jürgensmeier, Juliane M ^c   Susin, Santos A ^a   Vieira, Helena L A ^a   Prévost, Marie Christine ^d   Xie, Zhihua ^c   Matsuyama, Shigemi ^c   Reed, John C ^c   Kroemer, Guido ^a  

^a CNRS   (France)

^b UNIVERSITÉ DE TECHNOLOGIE DE COMPIÈGNE   (France)

^c BURNHAM INSTITUTE   (United States)

^d INSTITUT PASTEUR   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; PROTEIN BAX;

APOPTOSIS; ARTICLE; CELL MEMBRANE PERMEABILITY; GENE EXPRESSION; IMMUNOPRECIPITATION; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION;

ANIMALS; APOPTOSIS; ATRACTYLOSIDE; BCL-2-ASSOCIATED X PROTEIN; BINDING SITES; BONGKREKIC ACID; CYCLOSPORINE; DIMERIZATION; HT29 CELLS; HUMANS; INTRACELLULAR MEMBRANES; LIPOSOMES; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MITOCHONDRIAL ADP, ATP TRANSLOCASES; PERMEABILITY; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, WISTAR; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; TRANSFECTION;

EID: 0032566649     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.281.5385.2027     Document Type: Article

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52. -/- mice; N. Roy for ANT plasmid; H. Schmid for the ANT-specific antibody; A. Zweibaum for HT29 cells; and N. Larochette and D. Métivier for technical assistance. Supported by Agence Nationale pour la Recherche sur le SIDA, Association pour la Recherche sur le Cancer, CNRS, Fondation pour la Recherche Médicale, and Ligue Française contre le Cancer (to G.K.), and University of California Breast Cancer Research Program (grant number IRB-009B) and CapCure Incorporated (to J.C.R.). S.A.S. and E.L.A.V. receive fellowships from the European Commission, I.M. from the Spanish Ministry of Science, and J.M.J. from the Deutsche Forschungsgemeinschaft.