Gene expression during ER stress-induced apoptosis in neurons: Induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway

Journal of Cell Biology

Volumn 162, Issue 4, 2003, Pages 587-597

  Reimertz, Claus ^a,b   Kögel, Donat ^a,b   Rami, Abdelhaq ^b   Chittenden, Thomas ^c   Prehn, Jochen H M ^a,b  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^c IMMUNOGEN INC   (United States)

Author keywords

BH3 only proteins; Ischemia; Mitochondrial apoptosis pathway; Transcriptome analysis; Unfolded protein response

Indexed keywords

BH3 PROTEIN; CASPASE; CASPASE 3; CASPASE 9; CYTOCHROME C; PROTEIN; PROTEIN BCL XL; THAPSIGARGIN; TUNICAMYCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BCL 2 BINDING COMPONENT 3 GENE; BRAIN ISCHEMIA; CELL DEATH; CONTROLLED STUDY; DEGENERATIVE DISEASE; DNA MICROARRAY; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; FOREBRAIN; GENE; GENE EXPRESSION; GENE INDUCTION; GENE OVEREXPRESSION; HIPPOCAMPUS; HUMAN; HUMAN CELL; ISCHEMIA; MALE; MITOCHONDRION; NERVE CELL; NEUROBLASTOMA CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; P53 UPREGULATED MODULATOR OF APOPTOSIS GENE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN GLYCOSYLATION; RAT; STRESS; TRANSCRIPTION INITIATION;

ANTI-BACTERIAL AGENTS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; CALCIUM; ENDOPLASMIC RETICULUM; GENE EXPRESSION PROFILING; HUMANS; MITOCHONDRIA; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEPTIDE FRAGMENTS; PROTEIN FOLDING; PROTEINS; PROTO-ONCOGENE PROTEINS; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53; TUNICAMYCIN;

ANIMALIA;

EID: 0042477717     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200305149     Document Type: Article

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