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Volumn 20, Issue 13, 2009, Pages 3077-3087

PUMA promotes bax translocation by both directly interacting with bax and by competitive binding to Bcl-XL during UV-induced apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOHEXIMIDE; PIFITHRIN ALPHA; PROTEIN BAX; PROTEIN BCL XL; PROTEIN P53; PUMA PROTEIN;

EID: 67650444323     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E08-11-1109     Document Type: Article
Times cited : (75)

References (53)
  • 1
    • 0035146929 scopus 로고    scopus 로고
    • Life-or-death decisions by the Bcl-2 protein family
    • Adams, J. M., and Cory, S. (2001). Life-or-death decisions by the Bcl-2 protein family. Trends Biochem. Sci. 26, 61-66.
    • (2001) Trends Biochem. Sci , vol.26 , pp. 61-66
    • Adams, J.M.1    Cory, S.2
  • 2
    • 9744244990 scopus 로고    scopus 로고
    • The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA
    • Cartron, P. F., Gallenne, T., Bougras, G., Gautier, F., Manero, F., Vusio, P., Meflah, K., Vallette, F. M., and Juin, P. (2004). The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA. Mol. Cell 16, 807-818.
    • (2004) Mol. Cell , vol.16 , pp. 807-818
    • Cartron, P.F.1    Gallenne, T.2    Bougras, G.3    Gautier, F.4    Manero, F.5    Vusio, P.6    Meflah, K.7    Vallette, F.M.8    Juin, P.9
  • 3
    • 33646354381 scopus 로고    scopus 로고
    • Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
    • Certo, M., Del Gaizo Moore, V., Nishino, M., Wei, G., Korsmeyer, S., Armstrong, S. A., and Letai, A. (2006). Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members. Cancer Cell 9, 351-365.
    • (2006) Cancer Cell , vol.9 , pp. 351-365
    • Certo, M.1    Del Gaizo Moore, V.2    Nishino, M.3    Wei, G.4    Korsmeyer, S.5    Armstrong, S.A.6    Letai, A.7
  • 4
    • 0034665461 scopus 로고    scopus 로고
    • p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage
    • Chao, C., Saito, S., Kang, J., Anderson, C. W., Appella, E., and Xu, Y. (2000). p53 transcriptional activity is essential for p53-dependent apoptosis following DNA damage. EMBO J. 19, 4967-4975.
    • (2000) EMBO J , vol.19 , pp. 4967-4975
    • Chao, C.1    Saito, S.2    Kang, J.3    Anderson, C.W.4    Appella, E.5    Xu, Y.6
  • 5
  • 6
    • 0034786019 scopus 로고    scopus 로고
    • BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
    • Cheng, E. H., Wei, M. C., Weiler, S., Flavell, R. A., Mak, T. W., Lindsten, T., and Korsmeyer, S. J. (2001). BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis. Mol. Cell 8, 705-711.
    • (2001) Mol. Cell , vol.8 , pp. 705-711
    • Cheng, E.H.1    Wei, M.C.2    Weiler, S.3    Flavell, R.A.4    Mak, T.W.5    Lindsten, T.6    Korsmeyer, S.J.7
  • 7
    • 24644436766 scopus 로고    scopus 로고
    • PUMA couples the nuclear and cytoplasmic proapoptotic function of p53
    • Chipuk, J. E., Bouchier-Hayes, L., Kuwana, T., Newmeyer, D. D., and Green, D. R. (2005). PUMA couples the nuclear and cytoplasmic proapoptotic function of p53. Science 309, 1732-1735.
    • (2005) Science , vol.309 , pp. 1732-1735
    • Chipuk, J.E.1    Bouchier-Hayes, L.2    Kuwana, T.3    Newmeyer, D.D.4    Green, D.R.5
  • 9
    • 33947255054 scopus 로고    scopus 로고
    • Apoptosis induced by proteasome inhibition in cancer cells: Predominant role of the p53/PUMA pathway
    • Concannon, C. G., et al. (2007). Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway. Oncogene 26, 1681-1692.
    • (2007) Oncogene , vol.26 , pp. 1681-1692
    • Concannon, C.G.1
  • 10
    • 0142117313 scopus 로고    scopus 로고
    • The Bcl-2 family: Roles in cell survival and oncogenesis
    • Cory, S., Huang, D. C., and Adams, J. M. (2003). The Bcl-2 family: roles in cell survival and oncogenesis. Oncogene 22, 8590-8607.
    • (2003) Oncogene , vol.22 , pp. 8590-8607
    • Cory, S.1    Huang, D.C.2    Adams, J.M.3
  • 11
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: Critical control points
    • Danial, N. N., and Korsmeyer, S. J. (2004). Cell death: critical control points. Cell 116, 205-219.
    • (2004) Cell , vol.116 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 12
    • 20944438745 scopus 로고    scopus 로고
    • Oligomeric Bax is a component of the putative cytochrome c release channel MAC, mitochondrial apoptosis-induced channel
    • Dejean, L. M., et al. (2005). Oligomeric Bax is a component of the putative cytochrome c release channel MAC, mitochondrial apoptosis-induced channel. Mol. Biol. Cell 16, 2424-2432.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 2424-2432
    • Dejean, L.M.1
  • 14
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green, D. R., and Reed, J. C. (1998). Mitochondria and apoptosis. Science 281, 1309-1312.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 17
    • 10744228800 scopus 로고    scopus 로고
    • Puma is an essential mediator of p53-dependent and -independent apoptotic pathways
    • Jeffers, J. R., et al. (2003). Puma is an essential mediator of p53-dependent and -independent apoptotic pathways. Cancer Cell 4, 321-328.
    • (2003) Cancer Cell , vol.4 , pp. 321-328
    • Jeffers, J.R.1
  • 18
    • 13944277343 scopus 로고    scopus 로고
    • BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly
    • Kuwana, T., Bouchier-Hayes, L., Chipuk, J. E., Bonzon, C., Sullivan, B. A., Green, D. R., and Newmeyer, D. D. (2005). BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly. Mol. Cell 17, 525-535.
    • (2005) Mol. Cell , vol.17 , pp. 525-535
    • Kuwana, T.1    Bouchier-Hayes, L.2    Chipuk, J.E.3    Bonzon, C.4    Sullivan, B.A.5    Green, D.R.6    Newmeyer, D.D.7
  • 20
    • 0037418238 scopus 로고    scopus 로고
    • JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
    • Lei, K., and Davis, R. J. (2003). JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc. Natl. Acad. Sci. USA 100, 2432-2437.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 2432-2437
    • Lei, K.1    Davis, R.J.2
  • 21
    • 0036728834 scopus 로고    scopus 로고
    • Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics
    • Letai, A., Bassik, M. C., Walensky, L. D., Sorcinelli, M. D., Weiler, S., and Korsmeyer, S. J. (2002). Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. Cancer Cell 2, 183-192.
    • (2002) Cancer Cell , vol.2 , pp. 183-192
    • Letai, A.1    Bassik, M.C.2    Walensky, L.D.3    Sorcinelli, M.D.4    Weiler, S.5    Korsmeyer, S.J.6
  • 22
    • 0033229866 scopus 로고    scopus 로고
    • p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2
    • Li, P. F., Dietz, R., and von Harsdorf, R. (1999). p53 regulates mitochondrial membrane potential through reactive oxygen species and induces cytochrome c-independent apoptosis blocked by Bcl-2. EMBO J. 18, 6027-6036.
    • (1999) EMBO J , vol.18 , pp. 6027-6036
    • Li, P.F.1    Dietz, R.2    von Harsdorf, R.3
  • 23
    • 0035936797 scopus 로고    scopus 로고
    • The TNF and TNF receptor superfamilies: Integrating mammalian biology
    • Locksley, R. M., Killeen, N., and Lenardo, M. J. (2001). The TNF and TNF receptor superfamilies: integrating mammalian biology. Cell 104, 487-501.
    • (2001) Cell , vol.104 , pp. 487-501
    • Locksley, R.M.1    Killeen, N.2    Lenardo, M.J.3
  • 24
    • 0032555716 scopus 로고    scopus 로고
    • Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors
    • Luo, X., Budihardjo, I., Zou, H., Slaughter, C., and Wang, X. (1998). Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors. Cell 94, 481-490.
    • (1998) Cell , vol.94 , pp. 481-490
    • Luo, X.1    Budihardjo, I.2    Zou, H.3    Slaughter, C.4    Wang, X.5
  • 25
    • 33744942924 scopus 로고    scopus 로고
    • PUMA dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells
    • Ming, L., Wang, P., Bank, A., Yu, J., and Zhang, L. (2006). PUMA dissociates Bax and Bcl-X(L) to induce apoptosis in colon cancer cells. J. Biol. Chem. 281, 16034-16042.
    • (2006) J. Biol. Chem , vol.281 , pp. 16034-16042
    • Ming, L.1    Wang, P.2    Bank, A.3    Yu, J.4    Zhang, L.5
  • 26
    • 0035265686 scopus 로고    scopus 로고
    • PUMA, a novel proapoptotic gene, is induced by p53
    • Nakano, K., and Vousden, K. H. (2001). PUMA, a novel proapoptotic gene, is induced by p53. Mol. Cell 7, 683-694.
    • (2001) Mol. Cell , vol.7 , pp. 683-694
    • Nakano, K.1    Vousden, K.H.2
  • 27
    • 0033522391 scopus 로고    scopus 로고
    • Conformation of the Bax C-terminus regulates subcellular location and cell death
    • Nechushtan, A., Smith, C. L., Hsu, Y. T., and Youle, R. J. (1999). Conformation of the Bax C-terminus regulates subcellular location and cell death. EMBO J. 18, 2330-2341.
    • (1999) EMBO J , vol.18 , pp. 2330-2341
    • Nechushtan, A.1    Smith, C.L.2    Hsu, Y.T.3    Youle, R.J.4
  • 30
    • 0037860975 scopus 로고    scopus 로고
    • JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis
    • Putcha, G. V., et al. (2003). JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis. Neuron 38, 899-914.
    • (2003) Neuron , vol.38 , pp. 899-914
    • Putcha, G.V.1
  • 31
    • 0042477717 scopus 로고    scopus 로고
    • Gene expression during ER stress-induced apoptosis in neurons: Induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway
    • Reimertz, C., Kogel, D., Rami, A., Chittenden, T., and Prehn, J. H. (2003). Gene expression during ER stress-induced apoptosis in neurons: induction of the BH3-only protein Bbc3/PUMA and activation of the mitochondrial apoptosis pathway. J. Cell Biol. 162, 587-597.
    • (2003) J. Cell Biol , vol.162 , pp. 587-597
    • Reimertz, C.1    Kogel, D.2    Rami, A.3    Chittenden, T.4    Prehn, J.H.5
  • 32
    • 0034629291 scopus 로고    scopus 로고
    • p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release
    • Schuler, M., Bossy-Wetzel, E., Goldstein, J. C., Fitzgerald, P., and Green, D. R. (2000). p53 induces apoptosis by caspase activation through mitochondrial cytochrome c release. J. Biol. Chem. 275, 7337-7342.
    • (2000) J. Biol. Chem , vol.275 , pp. 7337-7342
    • Schuler, M.1    Bossy-Wetzel, E.2    Goldstein, J.C.3    Fitzgerald, P.4    Green, D.R.5
  • 34
    • 0029609086 scopus 로고
    • Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis
    • Strasser, A., Harris, A. W., Huang, D. C., Krammer, P. H., and Cory, S. (1995). Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis. EMBO J. 14, 6136-6147.
    • (1995) EMBO J , vol.14 , pp. 6136-6147
    • Strasser, A.1    Harris, A.W.2    Huang, D.C.3    Krammer, P.H.4    Cory, S.5
  • 35
    • 0028072523 scopus 로고
    • DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2
    • Strasser, A., Harris, A. W., Jacks, T., and Cory, S. (1994). DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2. Cell 79, 329-339.
    • (1994) Cell , vol.79 , pp. 329-339
    • Strasser, A.1    Harris, A.W.2    Jacks, T.3    Cory, S.4
  • 36
    • 0037134431 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria
    • Tsuruta, F., Masuyama, N., and Gotoh, Y. (2002). The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria. J. Biol. Chem. 277, 14040-14047.
    • (2002) J. Biol. Chem , vol.277 , pp. 14040-14047
    • Tsuruta, F.1    Masuyama, N.2    Gotoh, Y.3
  • 37
    • 0041977046 scopus 로고    scopus 로고
    • Spatial and temporal changes in Bax subcellular localization during anoikis
    • Valentijn, A. J., Metcalfe, A. D., Kott, J., Streuli, C. H., and Gilmore, A. P. (2003). Spatial and temporal changes in Bax subcellular localization during anoikis. J. Cell Biol. 162, 599-612.
    • (2003) J. Cell Biol , vol.162 , pp. 599-612
    • Valentijn, A.J.1    Metcalfe, A.D.2    Kott, J.3    Streuli, C.H.4    Gilmore, A.P.5
  • 38
    • 0033258120 scopus 로고    scopus 로고
    • Bcl-2 proteins: Regulators of apoptosis or of mitochondrial homeostasis?
    • Vander Heiden, M. G., and Thompson, C. B. (1999). Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis? Nat. Cell Biol. 1, E209-E216.
    • (1999) Nat. Cell Biol , vol.1
    • Vander Heiden, M.G.1    Thompson, C.B.2
  • 40
    • 0036674617 scopus 로고    scopus 로고
    • Live or let die: The cell's response to p53
    • Vousden, K. H., and Lu, X. (2002). Live or let die: the cell's response to p53. Nat. Rev. Cancer 2, 594-604.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 594-604
    • Vousden, K.H.1    Lu, X.2
  • 41
    • 0031660082 scopus 로고    scopus 로고
    • Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing
    • Wang, K., Gross, A., Waksman, G., and Korsmeyer, S. J. (1998). Mutagenesis of the BH3 domain of BAX identifies residues critical for dimerization and killing. Mol. Cell. Biol. 18, 6083-6089.
    • (1998) Mol. Cell. Biol , vol.18 , pp. 6083-6089
    • Wang, K.1    Gross, A.2    Waksman, G.3    Korsmeyer, S.J.4
  • 42
    • 34247211554 scopus 로고    scopus 로고
    • The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage
    • Wang, P., Yu, J., and Zhang, L. (2007). The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage. Proc. Natl. Acad. Sci. USA 104, 4054-4059.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 4054-4059
    • Wang, P.1    Yu, J.2    Zhang, L.3
  • 43
    • 0035890085 scopus 로고    scopus 로고
    • The expanding role of mitochondria in apoptosis
    • Wang, X. (2001). The expanding role of mitochondria in apoptosis. Genes Dev. 15, 2922-2933.
    • (2001) Genes Dev , vol.15 , pp. 2922-2933
    • Wang, X.1
  • 44
    • 22244464818 scopus 로고    scopus 로고
    • Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins
    • Willis, S. N., Chen, L., Dewson, G., Wei, A., Naik, E., Fletcher, J. I., Adams, J. M., and Huang, D. C. (2005). Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins. Genes Dev. 19, 1294-1305.
    • (2005) Genes Dev , vol.19 , pp. 1294-1305
    • Willis, S.N.1    Chen, L.2    Dewson, G.3    Wei, A.4    Naik, E.5    Fletcher, J.I.6    Adams, J.M.7    Huang, D.C.8
  • 45
    • 33846964621 scopus 로고    scopus 로고
    • Willis, S. N., et al. (2007). Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak. Science 315, 856-859.
    • Willis, S. N., et al. (2007). Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak. Science 315, 856-859.
  • 46
    • 34948846604 scopus 로고    scopus 로고
    • Bid is not required for Bax translocation during UV-induced apoptosis
    • Wu, Y., Xing, D., Chen, W. R., and Wang, X. (2007). Bid is not required for Bax translocation during UV-induced apoptosis. Cell Signal. 19, 2468-2478.
    • (2007) Cell Signal , vol.19 , pp. 2468-2478
    • Wu, Y.1    Xing, D.2    Chen, W.R.3    Wang, X.4
  • 48
    • 0037452759 scopus 로고    scopus 로고
    • PUMA mediates the apoptotic response to p53 in colorectal cancer cells
    • Yu, J., Wang, Z., Kinzler, K. W., Vogelstein, B., and Zhang, L. (2003). PUMA mediates the apoptotic response to p53 in colorectal cancer cells. Proc. Natl. Acad. Sci. USA 100, 1931-1936.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 1931-1936
    • Yu, J.1    Wang, Z.2    Kinzler, K.W.3    Vogelstein, B.4    Zhang, L.5
  • 49
    • 33646741204 scopus 로고    scopus 로고
    • PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation
    • Yu, J., Yue, W., Wu, B., and Zhang, L. (2006). PUMA sensitizes lung cancer cells to chemotherapeutic agents and irradiation. Clin. Cancer Res. 12, 2928-2936.
    • (2006) Clin. Cancer Res , vol.12 , pp. 2928-2936
    • Yu, J.1    Yue, W.2    Wu, B.3    Zhang, L.4
  • 50
    • 0142227023 scopus 로고    scopus 로고
    • No PUMA, no death: Implications for p53-dependent apoptosis
    • Yu, J., and Zhang, L. (2003). No PUMA, no death: implications for p53-dependent apoptosis. Cancer Cell 4, 248-249.
    • (2003) Cancer Cell , vol.4 , pp. 248-249
    • Yu, J.1    Zhang, L.2
  • 51
    • 2442520504 scopus 로고    scopus 로고
    • Apoptosis in human cancer cells
    • Yu, J., and Zhang, L. (2004). Apoptosis in human cancer cells. Curr. Opin. Oncol. 16, 19-24.
    • (2004) Curr. Opin. Oncol , vol.16 , pp. 19-24
    • Yu, J.1    Zhang, L.2
  • 52
    • 0035265823 scopus 로고    scopus 로고
    • PUMA induces the rapid apoptosis of colorectal cancer cells
    • Yu, J., Zhang, L., Hwang, P. M., Kinzler, K. W., and Vogelstein, B. (2001). PUMA induces the rapid apoptosis of colorectal cancer cells. Mol. Cell 7, 673-682.
    • (2001) Mol. Cell , vol.7 , pp. 673-682
    • Yu, J.1    Zhang, L.2    Hwang, P.M.3    Kinzler, K.W.4    Vogelstein, B.5
  • 53
    • 21244472965 scopus 로고    scopus 로고
    • Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis
    • Zhong, Q., Gao, W., Du, F., and Wang, X. (2005). Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis. Cell 121, 1085-1095.
    • (2005) Cell , vol.121 , pp. 1085-1095
    • Zhong, Q.1    Gao, W.2    Du, F.3    Wang, X.4


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