Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis

Cell

Volumn 152, Issue 3, 2013, Pages 519-531

  Czabotar, Peter E ^a,b   Westphal, Dana ^a,b   Dewson, Grant ^a,b   Ma, Stephen ^a,b   Hockings, Colin ^a,b   Fairlie, W Douglas ^a,b   Lee, Erinna F ^a,b   Yao, Shenggen ^a,b   Robin, Adeline Y ^a,b   Smith, Brian J ^c   Huang, David C S ^a,b   Kluck, Ruth M ^a,b   Adams, Jerry M ^a,b   Colman, Peter M ^a,b  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c LA TROBE UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BH3 PROTEIN; DETERGENT; HOMODIMER; PROTEIN BAX;

AMINO ACID SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; EMBRYO; LIPOPHILICITY; MOUSE; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN SECRETION; PROTEIN STRUCTURE; SURVIVAL;

EID: 84873307384     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2012.12.031     Document Type: Article

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