Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice

Journal of Cerebral Blood Flow and Metabolism

Volumn 28, Issue 9, 2008, Pages 1564-1573

  You, Zerong ^a   Savitz, Sean I ^a,b   Yang, Jinsheng ^a   Degterev, Alexei ^c   Yuan, Junying ^c   Cuny, Gregory D ^d   Moskowitz, Michael A ^a   Whalen, Michael J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Inflammation; Mice; Necroptosis; Necrosis; Necrostatin; Traumatic brain injury

Indexed keywords

CASPASE 3; INHIBITOR PROTEIN; NECROSTATIN 1; PROPIDIUM IODIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BRAIN CORTEX; BRAIN DAMAGE; CELL ACTIVATION; CONTROLLED STUDY; DENTATE GYRUS; HISTOPATHOLOGY; MAZE TEST; MICROGLIA; MOTOR PERFORMANCE; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; SPATIAL MEMORY; TRAUMATIC BRAIN INJURY;

ANIMALS; BRAIN INJURIES; CASPASE 3; CEREBRAL CORTEX; DENTATE GYRUS; IMIDAZOLES; INDOLES; MAZE LEARNING; MICE; MOTOR SKILLS; NECROSIS; TREATMENT OUTCOME;

EID: 50249132439     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1038/jcbfm.2008.44     Document Type: Article

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