A novel role for RIP1 kinase in mediating TNFa production

Cell Death and Disease

Volumn 3, Issue 6, 2012, Pages

  Christofferson, D E ^a   Li, Y ^a   Hitomi, J ^a   Zhou, W ^a   Upperman, C ^a   Zhu, H ^a   Gerber, S A ^a   Gygi, S ^a   Yuan, J ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

inflammation; necroptosis; necrostatin; RIP1; TNF

Indexed keywords

CASPASE; CASPASE INHIBITOR; CELL PROTEIN; DEATH RECEPTOR; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN 1; INHIBITOR OF APOPTOSIS PROTEIN 2; NECROSTATIN 1; PROTEIN EDD; PROTEIN P100; PROTEIN P52; PROTEIN SERINE THREONINE KINASE; RIP1 KINASE; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR SP1; TUBULIN; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 2; UNCLASSIFIED DRUG; EDD PROTEIN, MOUSE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; RALBP1 PROTEIN, MOUSE; UBIQUITIN PROTEIN LIGASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOCRINE EFFECT; CELL TYPE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL LINE; METABOLISM;

ANIMALS; APOPTOSIS; CASPASE INHIBITORS; CASPASES; CELL LINE; GTPASE-ACTIVATING PROTEINS; MICE; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 2; TUMOR NECROSIS FACTOR-ALPHA; UBIQUITIN-PROTEIN LIGASES;

EID: 84863486901     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2012.64     Document Type: Article

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