-
1
-
-
15244350902
-
Targeting the gatekeeper residue in phosphoinositide 3-kinases
-
Alaimo P.J., Knight Z.A., and Shokat K.M. Targeting the gatekeeper residue in phosphoinositide 3-kinases. Bioorg. Med. Chem. 13 (2005) 2825-2836
-
(2005)
Bioorg. Med. Chem.
, vol.13
, pp. 2825-2836
-
-
Alaimo, P.J.1
Knight, Z.A.2
Shokat, K.M.3
-
2
-
-
0034625182
-
p110beta is up-regulated during differentiation of 3T3-L1 cells and contributes to the highly insulin-responsive glucose transport activity
-
Asano T., Kanda A., Katagiri H., Nawano M., Ogihara T., Inukai K., Anai M., Fukushima Y., Yazaki Y., Kikuchi M., et al. p110beta is up-regulated during differentiation of 3T3-L1 cells and contributes to the highly insulin-responsive glucose transport activity. J. Biol. Chem. 275 (2000) 17671-17676
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 17671-17676
-
-
Asano, T.1
Kanda, A.2
Katagiri, H.3
Nawano, M.4
Ogihara, T.5
Inukai, K.6
Anai, M.7
Fukushima, Y.8
Yazaki, Y.9
Kikuchi, M.10
-
3
-
-
33646527978
-
-
Barvian, N.C., Kolz, C.N., Para, K.S., Patt, W.C., and Viskick, M. June 2004. Benzoxazin-3-ones and derivatives thereof as inhibitors of PI3K. WO 04/052373.
-
-
-
-
4
-
-
0033574429
-
Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase
-
Bi L., Okabe I., Bernard D.J., Wynshaw-Boris A., and Nussbaum R.L. Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase. J. Biol. Chem. 274 (1999) 10963-10968
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 10963-10968
-
-
Bi, L.1
Okabe, I.2
Bernard, D.J.3
Wynshaw-Boris, A.4
Nussbaum, R.L.5
-
5
-
-
0036185944
-
Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI 3-kinase
-
Bi L., Okabe I., Bernard D.J., and Nussbaum R.L. Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI 3-kinase. Mamm. Genome 13 (2002) 169-172
-
(2002)
Mamm. Genome
, vol.13
, pp. 169-172
-
-
Bi, L.1
Okabe, I.2
Bernard, D.J.3
Nussbaum, R.L.4
-
6
-
-
14144250240
-
Phosphoinositide 3-kinase catalytic subunit deletion and regulatory subunit deletion have opposite effects on insulin sensitivity in mice
-
Brachmann S.M., Ueki K., Engelman J.A., Kahn R.C., and Cantley L.C. Phosphoinositide 3-kinase catalytic subunit deletion and regulatory subunit deletion have opposite effects on insulin sensitivity in mice. Mol. Cell. Biol. 25 (2005) 1596-1607
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 1596-1607
-
-
Brachmann, S.M.1
Ueki, K.2
Engelman, J.A.3
Kahn, R.C.4
Cantley, L.C.5
-
7
-
-
33646496559
-
-
Bruce, I., Finan, P., Leblanc, C., McCarthy, C., Whitehead, L., Blair, N., Bloomfield, G., Hayler, J., Kirman, L., Oza, M., and Shukla, L. September 2003. 5-phenylthiazole derivatives and use as PI3 kinase inhibitors. WO 03/072557.
-
-
-
-
8
-
-
24744435115
-
Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis
-
Camps M., Ruckle T., Ji H., Ardissone V., Rintelen F., Shaw J., Ferrandi C., Chabert C., Gillieron C., Francon B., et al. Blockade of PI3Kgamma suppresses joint inflammation and damage in mouse models of rheumatoid arthritis. Nat. Med. 11 (2005) 936-943
-
(2005)
Nat. Med.
, vol.11
, pp. 936-943
-
-
Camps, M.1
Ruckle, T.2
Ji, H.3
Ardissone, V.4
Rintelen, F.5
Shaw, J.6
Ferrandi, C.7
Chabert, C.8
Gillieron, C.9
Francon, B.10
-
9
-
-
0033551070
-
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway
-
Cantley L.C., and Neel B.G. New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc. Natl. Acad. Sci. USA 96 (1999) 4240-4245
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 4240-4245
-
-
Cantley, L.C.1
Neel, B.G.2
-
10
-
-
23744492188
-
Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils
-
Condliffe A.M., Davidson K., Anderson K.E., Ellson C.D., Crabbe T., Okkenhaug K., Vanhaesebroeck B., Turner M., Webb L., Wymann M.P., et al. Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils. Blood 106 (2005) 1432-1440
-
(2005)
Blood
, vol.106
, pp. 1432-1440
-
-
Condliffe, A.M.1
Davidson, K.2
Anderson, K.E.3
Ellson, C.D.4
Crabbe, T.5
Okkenhaug, K.6
Vanhaesebroeck, B.7
Turner, M.8
Webb, L.9
Wymann, M.P.10
-
11
-
-
0030790548
-
Using structure to define the function of phosphoinositide 3-kinase family members
-
Domin J., and Waterfield M.D. Using structure to define the function of phosphoinositide 3-kinase family members. FEBS Lett. 410 (1997) 91-95
-
(1997)
FEBS Lett.
, vol.410
, pp. 91-95
-
-
Domin, J.1
Waterfield, M.D.2
-
12
-
-
33646382364
-
A dual PI3-kinase/mTOR inhibitor reveals emergent efficacy in glioma
-
Fan Q.-W., Knight Z.A., Goldenberg D.D., Yu W., Mostov K.E., Stokoe D., Shokat K.M., and Weiss W.A. A dual PI3-kinase/mTOR inhibitor reveals emergent efficacy in glioma. Cancer Cell 9 (2006) 341-349
-
(2006)
Cancer Cell
, vol.9
, pp. 341-349
-
-
Fan, Q.-W.1
Knight, Z.A.2
Goldenberg, D.D.3
Yu, W.4
Mostov, K.E.5
Stokoe, D.6
Shokat, K.M.7
Weiss, W.A.8
-
13
-
-
4644359805
-
Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase
-
Feng J., Park J., Cron P., Hess D., and Hemmings B.A. Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase. J. Biol. Chem. 279 (2004) 41189-41196
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 41189-41196
-
-
Feng, J.1
Park, J.2
Cron, P.3
Hess, D.4
Hemmings, B.A.5
-
15
-
-
33646499650
-
-
Halbrook, J., Kesicki, E., Burgess, L.E., Schlachter, S.T., Eary, C.T., Schiro, J.G., Huang, H., Evans, M., and Han, Y. March 2002. Materials and methods to potentiate cancer treatment. WO 02/20500.
-
-
-
-
17
-
-
33646532265
-
-
Hayakawa, M., Kaizawa, H., Kawaguchi, K., Matsuda, K., Ishikawa, N., Koizumi, T., Yamano, M., Okada, M., Ohta, M. January 2003a. Imidazopyridine derivatives. European patent 1,277,754.
-
-
-
-
18
-
-
33646528196
-
-
Hayakawa, M., Kaizawa, H., Moritoma, H., Kawaguchi, K., Koizumi, T., Yamano, M., Matsuda, K., Okada, M., Ohta, M. January 2003b. Condensed heteroaryl derivatives. European patent 1,277,738.
-
-
-
-
19
-
-
9744271049
-
Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM
-
Hickson I., Zhao Y., Richardson C.J., Green S.J., Martin N.M., Orr A.I., Reaper P.M., Jackson S.P., Curtin N.J., and Smith G.C. Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM. Cancer Res. 64 (2004) 9152-9159
-
(2004)
Cancer Res.
, vol.64
, pp. 9152-9159
-
-
Hickson, I.1
Zhao, Y.2
Richardson, C.J.3
Green, S.J.4
Martin, N.M.5
Orr, A.I.6
Reaper, P.M.7
Jackson, S.P.8
Curtin, N.J.9
Smith, G.C.10
-
20
-
-
33646525168
-
-
Jackson, S.P., Robertson, A.D., Kenche, V., Thompson, P., Prabaharan, H., Anderson, K., Abbott, B. Goncalves, I., Nesbitt, W., Shoenwaelder, S., and Saylik, D. February 2004. Inhibition of phosphoinositide 3-kinase beta. WO 04/016607.
-
-
-
-
21
-
-
21044454703
-
PI 3-kinase p110beta: a new target for antithrombotic therapy
-
Jackson S.P., Schoenwaelder S.M., Goncalves I., Nesbitt W.S., Yap C.L., Wright C.E., Kenche V., Anderson K.E., Dopheide S.M., Yuan Y., et al. PI 3-kinase p110beta: a new target for antithrombotic therapy. Nat. Med. 11 (2005) 507-514
-
(2005)
Nat. Med.
, vol.11
, pp. 507-514
-
-
Jackson, S.P.1
Schoenwaelder, S.M.2
Goncalves, I.3
Nesbitt, W.S.4
Yap, C.L.5
Wright, C.E.6
Kenche, V.7
Anderson, K.E.8
Dopheide, S.M.9
Yuan, Y.10
-
22
-
-
0035190026
-
Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer
-
Katso R., Okkenhaug K., Ahmadi K., White S., Timms J., and Waterfield M.D. Cellular function of phosphoinositide 3-kinases: implications for development, homeostasis, and cancer. Annu. Rev. Cell Dev. Biol. 17 (2001) 615-675
-
(2001)
Annu. Rev. Cell Dev. Biol.
, vol.17
, pp. 615-675
-
-
Katso, R.1
Okkenhaug, K.2
Ahmadi, K.3
White, S.4
Timms, J.5
Waterfield, M.D.6
-
23
-
-
24944497371
-
Features of selective kinase inhibitors
-
Knight Z.A., and Shokat K.M. Features of selective kinase inhibitors. Chem. Biol. 12 (2005) 621-637
-
(2005)
Chem. Biol.
, vol.12
, pp. 621-637
-
-
Knight, Z.A.1
Shokat, K.M.2
-
24
-
-
3843135141
-
Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold
-
Knight Z.A., Chiang G.G., Alaimo P.J., Kenski D.M., Ho C.B., Coan K., Abraham R.T., and Shokat K.M. Isoform-specific phosphoinositide 3-kinase inhibitors from an arylmorpholine scaffold. Bioorg. Med. Chem. 12 (2004) 4749-4759
-
(2004)
Bioorg. Med. Chem.
, vol.12
, pp. 4749-4759
-
-
Knight, Z.A.1
Chiang, G.G.2
Alaimo, P.J.3
Kenski, D.M.4
Ho, C.B.5
Coan, K.6
Abraham, R.T.7
Shokat, K.M.8
-
25
-
-
0037259062
-
Analysis of insulin-stimulated glucose uptake in differentiated 3T3-L1 adipocytes
-
Lakshmanan J., Elmendorf J.S., and Ozcan S. Analysis of insulin-stimulated glucose uptake in differentiated 3T3-L1 adipocytes. Methods Mol. Med. 83 (2003) 97-103
-
(2003)
Methods Mol. Med.
, vol.83
, pp. 97-103
-
-
Lakshmanan, J.1
Elmendorf, J.S.2
Ozcan, S.3
-
26
-
-
18344388668
-
Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase
-
Lau A., Swinbank K.M., Ahmed P.S., Taylor D.L., Jackson S.P., Smith G.C., and O'Connor M.J. Suppression of HIV-1 infection by a small molecule inhibitor of the ATM kinase. Nat. Cell Biol. 7 (2005) 493-500
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 493-500
-
-
Lau, A.1
Swinbank, K.M.2
Ahmed, P.S.3
Taylor, D.L.4
Jackson, S.P.5
Smith, G.C.6
O'Connor, M.J.7
-
27
-
-
23744456586
-
The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complex
-
Luo J., Field S.J., Lee J.Y., Engelman J.A., and Cantley L.C. The p85 regulatory subunit of phosphoinositide 3-kinase down-regulates IRS-1 signaling via the formation of a sequestration complex. J. Cell Biol. 170 (2005) 455-464
-
(2005)
J. Cell Biol.
, vol.170
, pp. 455-464
-
-
Luo, J.1
Field, S.J.2
Lee, J.Y.3
Engelman, J.A.4
Cantley, L.C.5
-
28
-
-
0028331080
-
cAMP-dependent protein-kinase-crystallographic insights into substrate recognition and phosphotransfer
-
Madhusudan, Trafny E.A., Xuong N.H., Adams J.A., Teneyck L.F., Taylor S.S., and Sowadski J.M. cAMP-dependent protein-kinase-crystallographic insights into substrate recognition and phosphotransfer. Protein Sci. 3 (1994) 176-187
-
(1994)
Protein Sci.
, vol.3
, pp. 176-187
-
-
Madhusudan1
Trafny, E.A.2
Xuong, N.H.3
Adams, J.A.4
Teneyck, L.F.5
Taylor, S.S.6
Sowadski, J.M.7
-
29
-
-
4344714889
-
PI3Kγ modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects
-
Patrucco E., Notte A., Barberis L., Selvetella G., Maffei A., Brancaccio M., Marengo S., Russo G., Azzolino O., Rybalkin S.D., et al. PI3Kγ modulates the cardiac response to chronic pressure overload by distinct kinase-dependent and -independent effects. Cell 118 (2004) 375-387
-
(2004)
Cell
, vol.118
, pp. 375-387
-
-
Patrucco, E.1
Notte, A.2
Barberis, L.3
Selvetella, G.4
Maffei, A.5
Brancaccio, M.6
Marengo, S.7
Russo, G.8
Azzolino, O.9
Rybalkin, S.D.10
-
30
-
-
16444384872
-
Deficiency in the catalytic subunit of DNA-dependent protein kinase causes down-regulation of ATM
-
Peng Y., Woods R.G., Beamish H., Ye R., Lees-Miller S.P., Lavin M.F., and Bedford J.S. Deficiency in the catalytic subunit of DNA-dependent protein kinase causes down-regulation of ATM. Cancer Res. 65 (2005) 1670-1677
-
(2005)
Cancer Res.
, vol.65
, pp. 1670-1677
-
-
Peng, Y.1
Woods, R.G.2
Beamish, H.3
Ye, R.4
Lees-Miller, S.P.5
Lavin, M.F.6
Bedford, J.S.7
-
31
-
-
33646510839
-
-
Robertson, A.D., Jackson, S., Kenche, V., Yaip, C., Parbaharan, H., and Thompson, P. July 2001. Therapeutic morpholino-substituted compounds. WO 01/53266.
-
-
-
-
33
-
-
33646498296
-
-
Sadhu, C., Dick, K., Treiberg, J., Sowell, C., Kesicki, E.A., and Oliver, A. April 2001. Inhibitors of human phosphatidyl-inositol 3-kinase delta. WO 01/81346.
-
-
-
-
34
-
-
0037369696
-
Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement
-
Sadhu C., Masinovsky B., Dick K., Sowell C.G., and Staunton D.E. Essential role of phosphoinositide 3-kinase delta in neutrophil directional movement. J. Immunol. 170 (2003) 2647-2654
-
(2003)
J. Immunol.
, vol.170
, pp. 2647-2654
-
-
Sadhu, C.1
Masinovsky, B.2
Dick, K.3
Sowell, C.G.4
Staunton, D.E.5
-
35
-
-
11144358645
-
High frequency of mutations of the PIK3CA gene in human cancers
-
Samuels Y., Wang Z., Bardelli A., Silliman N., Ptak J., Szabo S., Yan H., Gazdar A., Powell S.M., Riggins G.J., et al. High frequency of mutations of the PIK3CA gene in human cancers. Science 304 (2004) 554
-
(2004)
Science
, vol.304
, pp. 554
-
-
Samuels, Y.1
Wang, Z.2
Bardelli, A.3
Silliman, N.4
Ptak, J.5
Szabo, S.6
Yan, H.7
Gazdar, A.8
Powell, S.M.9
Riggins, G.J.10
-
36
-
-
0033063429
-
Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor
-
Schindler T., Sicheri F., Pico A., Gazit A., Levitzki A., and Kuriyan J. Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor. Mol. Cell 3 (1999) 639-648
-
(1999)
Mol. Cell
, vol.3
, pp. 639-648
-
-
Schindler, T.1
Sicheri, F.2
Pico, A.3
Gazit, A.4
Levitzki, A.5
Kuriyan, J.6
-
37
-
-
0034665713
-
Structural mechanism for STI-571 inhibition of abelson tyrosine kinase
-
Schindler T., Bornmann W., Pellicena P., Miller W.T., Clarkson B., and Kuriyan J. Structural mechanism for STI-571 inhibition of abelson tyrosine kinase. Science 289 (2000) 1938-1942
-
(2000)
Science
, vol.289
, pp. 1938-1942
-
-
Schindler, T.1
Bornmann, W.2
Pellicena, P.3
Miller, W.T.4
Clarkson, B.5
Kuriyan, J.6
-
39
-
-
0025988995
-
Identification and quantification of polyphosphoinositides produced in response to platelet-derived growth factor stimulation
-
Serunian L.A., Auger K.R., and Cantley L.C. Identification and quantification of polyphosphoinositides produced in response to platelet-derived growth factor stimulation. Methods Enzymol. 198 (1991) 78-87
-
(1991)
Methods Enzymol.
, vol.198
, pp. 78-87
-
-
Serunian, L.A.1
Auger, K.R.2
Cantley, L.C.3
-
40
-
-
33646522175
-
-
Shimada, M., Murata, T., Fuchikami, K., Tsujishita, H., Omori, N., Kato, I., Miura, M., Urbahns, K., Gantner, F., and Bacon, K. April 2004. Fused azole-pyrimidine derivatives. WO 04/029055.
-
-
-
-
41
-
-
33646519874
-
-
Smith, G.C., Martin, N.M., Jackson, S.P., O'Connor, M.J., Lau, A.Y., Cockcroft, X.F., Matthews, I.T., Menear, K.A., Rigoreau, L.J., Hummerson, M.G., and Griffin, R.J. August 2003. Pyranones useful as ATM inhibitors. WO 03/070726.
-
-
-
-
42
-
-
0037039317
-
Increased insulin sensitivity in mice lacking p85beta subunit of phosphoinositide 3-kinase
-
Ueki K., Yballe C.M., Brachmann S.M., Vicent D., Watt J.M., Kahn C.R., and Cantley L.C. Increased insulin sensitivity in mice lacking p85beta subunit of phosphoinositide 3-kinase. Proc. Natl. Acad. Sci. USA 99 (2002) 419-424
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 419-424
-
-
Ueki, K.1
Yballe, C.M.2
Brachmann, S.M.3
Vicent, D.4
Watt, J.M.5
Kahn, C.R.6
Cantley, L.C.7
-
43
-
-
0346220260
-
Positive and negative roles of p85 alpha and p85 beta regulatory subunits of phosphoinositide 3-kinase in insulin signaling
-
Ueki K., Fruman D.A., Yballe C.M., Fasshauer M., Klein J., Asano T., Cantley L.C., and Kahn C.R. Positive and negative roles of p85 alpha and p85 beta regulatory subunits of phosphoinositide 3-kinase in insulin signaling. J. Biol. Chem. 278 (2003) 48453-48466
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 48453-48466
-
-
Ueki, K.1
Fruman, D.A.2
Yballe, C.M.3
Fasshauer, M.4
Klein, J.5
Asano, T.6
Cantley, L.C.7
Kahn, C.R.8
-
44
-
-
16244393685
-
Signalling by PI3K isoforms: insights from gene-targeted mice
-
Vanhaesebroeck B., Ali K., Bilancio A., Geering B., and Foukas L.C. Signalling by PI3K isoforms: insights from gene-targeted mice. Trends Biochem. Sci. 30 (2005) 194-204
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 194-204
-
-
Vanhaesebroeck, B.1
Ali, K.2
Bilancio, A.3
Geering, B.4
Foukas, L.C.5
-
45
-
-
20044390541
-
Full activation of PKB/Akt in response to insulin or ionizing radiation is mediated through ATM
-
Viniegra J.G., Martinez N., Modirassari P., Losa J.H., Parada Cobo C., Lobo V.J., Luquero C.I., Alvarez-Vallina L., Ramon y Cajal S., Rojas J.M., and Sanchez-Prieto R. Full activation of PKB/Akt in response to insulin or ionizing radiation is mediated through ATM. J. Biol. Chem. 280 (2005) 4029-4036
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 4029-4036
-
-
Viniegra, J.G.1
Martinez, N.2
Modirassari, P.3
Losa, J.H.4
Parada Cobo, C.5
Lobo, V.J.6
Luquero, C.I.7
Alvarez-Vallina, L.8
Ramon y Cajal, S.9
Rojas, J.M.10
Sanchez-Prieto, R.11
-
46
-
-
0033581886
-
Structural insights into phosphoinositide 3-kinase catalysis and signalling
-
Walker E.H., Perisic O., Ried C., Stephens L., and Williams R.L. Structural insights into phosphoinositide 3-kinase catalysis and signalling. Nature 402 (1999) 313-320
-
(1999)
Nature
, vol.402
, pp. 313-320
-
-
Walker, E.H.1
Perisic, O.2
Ried, C.3
Stephens, L.4
Williams, R.L.5
-
47
-
-
0033634827
-
Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine
-
Walker E.H., Pacold M.E., Perisic O., Stephens L., Hawkins P.T., Wymann M.P., and Williams R.L. Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine. Mol. Cell 6 (2000) 909-919
-
(2000)
Mol. Cell
, vol.6
, pp. 909-919
-
-
Walker, E.H.1
Pacold, M.E.2
Perisic, O.3
Stephens, L.4
Hawkins, P.T.5
Wymann, M.P.6
Williams, R.L.7
-
48
-
-
0037350266
-
Therapeutic potential of phosphoinositide 3-kinase inhibitors
-
Ward S., Sotsios Y., Dowden J., Bruce I., and Finan P. Therapeutic potential of phosphoinositide 3-kinase inhibitors. Chem. Biol. 10 (2003) 207-213
-
(2003)
Chem. Biol.
, vol.10
, pp. 207-213
-
-
Ward, S.1
Sotsios, Y.2
Dowden, J.3
Bruce, I.4
Finan, P.5
-
49
-
-
0037077201
-
A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid
-
Yart A., Roche S., Wetzker R., Laffargue M., Tonks N., Mayeux P., Chap H., and Raynal P. A function for phosphoinositide 3-kinase beta lipid products in coupling beta gamma to Ras activation in response to lysophosphatidic acid. J. Biol. Chem. 277 (2002) 21167-21178
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21167-21178
-
-
Yart, A.1
Roche, S.2
Wetzker, R.3
Laffargue, M.4
Tonks, N.5
Mayeux, P.6
Chap, H.7
Raynal, P.8
-
50
-
-
0031887249
-
Regulation of the p85/p110 phosphatidylinositol 3′-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit
-
Yu J., Zhang Y., McIlroy J., Rordorf-Nikolic T., Orr G.A., and Backer J.M. Regulation of the p85/p110 phosphatidylinositol 3′-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunit. Mol. Cell. Biol. 18 (1998) 1379-1387
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 1379-1387
-
-
Yu, J.1
Zhang, Y.2
McIlroy, J.3
Rordorf-Nikolic, T.4
Orr, G.A.5
Backer, J.M.6
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