Exacerbation of retinal degeneration in the absence of alpha crystallins in an in vivo model of chemically induced hypoxia

Experimental Eye Research

Volumn 86, Issue 2, 2008, Pages 355-365

  Yaung, Jennifer ^a,b   Kannan, Ram ^a,b,c   Wawrousek, Eric F ^d   Spee, Christine ^b,c   Sreekumar, Parameswaran G ^b,c   Hinton, David R ^a,b,c  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b Arnold and Mabel Beckman Macular Research Center   (United States)

^c DOHENY EYE INSTITUTE   (United States)

^d NATIONAL EYE INSTITUTE   (United States)

Author keywords

apoptosis; crystallins; hypoxia; oxidative stress; retinal degeneration; retinal pigment epithelium

Indexed keywords

ALPHA CRYSTALLIN; BETA CRYSTALLIN; COBALT CHLORIDE; EOSIN; HEMATOXYLIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOSOL; DISEASE EXACERBATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; IN VIVO STUDY; MITOCHONDRION; MOUSE; NICK END LABELING; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RETINA DEGENERATION; WESTERN BLOTTING;

ALPHA-CRYSTALLIN B CHAIN; ALPHA-CRYSTALLINS; ANIMALS; APOPTOSIS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; MICE; MICE, KNOCKOUT; MITOCHONDRIA; PIGMENT EPITHELIUM OF EYE; RETINAL DEGENERATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 39149145829     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2007.11.007     Document Type: Article

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