RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3

Nature

Volumn 498, Issue 7453, 2013, Pages 224-227

  Lukens, John R ^a   Vogel, Peter ^a   Johnson, Gordon R ^a   Kelliher, Michelle A ^b   Iwakura, Yoichiro ^c   Lamkanfi, Mohamed ^d,e   Kanneganti, Thirumala Devi ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF TOKYO   (Japan)

^d DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^e GHENT UNIVERSITY   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 1ALPHA; PROTEIN; PROTEIN TYROSINE PHOSPHATASE SHP 1; RECEPTOR INTERACTING PROTEIN 140; RECEPTOR INTERACTING PROTEIN 3; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID; DISEASE INCIDENCE; GENETIC ANALYSIS; MATURATION; MUTATION; PROTEIN; RODENT; SIGNALING;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE EXACERBATION; FOOT PAD; HEMATOPOIETIC CELL; INFLAMMATION; MOUSE; NECROPTOSIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SKIN ABRASION; TISSUE INJURY; WOUND HEALING;

ANIMALS; CELL DEATH; DERMATITIS; DISEASE MODELS, ANIMAL; EXTREMITIES; FEMALE; GENE DELETION; HUMANS; INFLAMMASOMES; INFLAMMATION; INTERLEUKIN-1ALPHA; INTERLEUKIN-1BETA; MALE; MICE; NF-KAPPA B; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; RECEPTOR-INTERACTING PROTEIN SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; WOUND HEALING; WOUNDS AND INJURIES;

MUS;

EID: 84878978627     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature12174     Document Type: Article

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