-
1
-
-
23044462592
-
Phosphorylation of FADD at serine 194 by CKIalpha regulates its nonapoptotic activities
-
Alappat E.C., Feig C., Boyerinas B., Volkland J., Samuels M., Murmann A.E., Thorburn A., Kidd V.J., Slaughter C.A., Osborn S.L., et al. Phosphorylation of FADD at serine 194 by CKIalpha regulates its nonapoptotic activities. Mol. Cell 2005, 19:321-332.
-
(2005)
Mol. Cell
, vol.19
, pp. 321-332
-
-
Alappat, E.C.1
Feig, C.2
Boyerinas, B.3
Volkland, J.4
Samuels, M.5
Murmann, A.E.6
Thorburn, A.7
Kidd, V.J.8
Slaughter, C.A.9
Osborn, S.L.10
-
2
-
-
15844375853
-
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
-
Baines C.P., Kaiser R.A., Purcell N.H., Blair N.S., Osinska H., Hambleton M.A., Brunskill E.W., Sayen M.R., Gottlieb R.A., Dorn G.W., et al. Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death. Nature 2005, 434:658-662.
-
(2005)
Nature
, vol.434
, pp. 658-662
-
-
Baines, C.P.1
Kaiser, R.A.2
Purcell, N.H.3
Blair, N.S.4
Osinska, H.5
Hambleton, M.A.6
Brunskill, E.W.7
Sayen, M.R.8
Gottlieb, R.A.9
Dorn, G.W.10
-
3
-
-
45149096045
-
Identification of a critical tyrosine residue in caspase 8 that promotes cell migration
-
Barbero S., Barilà D., Mielgo A., Stagni V., Clair K., Stupack D. Identification of a critical tyrosine residue in caspase 8 that promotes cell migration. J. Biol. Chem. 2008, 283:13031-13034.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13031-13034
-
-
Barbero, S.1
Barilà, D.2
Mielgo, A.3
Stagni, V.4
Clair, K.5
Stupack, D.6
-
4
-
-
65949097277
-
Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis
-
Barbero S., Mielgo A., Torres V., Teitz T., Shields D.J., Mikolon D., Bogyo M., Barilà D., Lahti J.M., Schlaepfer D., Stupack D.G. Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis. Cancer Res. 2009, 69:3755-3763.
-
(2009)
Cancer Res.
, vol.69
, pp. 3755-3763
-
-
Barbero, S.1
Mielgo, A.2
Torres, V.3
Teitz, T.4
Shields, D.J.5
Mikolon, D.6
Bogyo, M.7
Barilà, D.8
Lahti, J.M.9
Schlaepfer, D.10
Stupack, D.G.11
-
5
-
-
44949240664
-
CIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination
-
Bertrand M.J., Milutinovic S., Dickson K.M., Ho W.C., Boudreault A., Durkin J., Gillard J.W., Jaquith J.B., Morris S.J., Barker P.A. cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination. Mol. Cell 2008, 30:689-700.
-
(2008)
Mol. Cell
, vol.30
, pp. 689-700
-
-
Bertrand, M.J.1
Milutinovic, S.2
Dickson, K.M.3
Ho, W.C.4
Boudreault, A.5
Durkin, J.6
Gillard, J.W.7
Jaquith, J.B.8
Morris, S.J.9
Barker, P.A.10
-
6
-
-
79953282304
-
NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling
-
Biton S., Ashkenazi A. NEMO and RIP1 control cell fate in response to extensive DNA damage via TNF-α feedforward signaling. Cell 2011, 145:92-103.
-
(2011)
Cell
, vol.145
, pp. 92-103
-
-
Biton, S.1
Ashkenazi, A.2
-
7
-
-
1642433091
-
Syncytial fusion of human trophoblast depends on caspase 8
-
Black S., Kadyrov M., Kaufmann P., Ugele B., Emans N., Huppertz B. Syncytial fusion of human trophoblast depends on caspase 8. Cell Death Differ. 2004, 11:90-98.
-
(2004)
Cell Death Differ.
, vol.11
, pp. 90-98
-
-
Black, S.1
Kadyrov, M.2
Kaufmann, P.3
Ugele, B.4
Emans, N.5
Huppertz, B.6
-
8
-
-
0037291871
-
A unified model for apical caspase activation
-
Boatright K.M., Renatus M., Scott F.L., Sperandio S., Shin H., Pedersen I.M., Ricci J.E., Edris W.A., Sutherlin D.P., Green D.R., Salvesen G.S. A unified model for apical caspase activation. Mol. Cell 2003, 11:529-541.
-
(2003)
Mol. Cell
, vol.11
, pp. 529-541
-
-
Boatright, K.M.1
Renatus, M.2
Scott, F.L.3
Sperandio, S.4
Shin, H.5
Pedersen, I.M.6
Ricci, J.E.7
Edris, W.A.8
Sutherlin, D.P.9
Green, D.R.10
Salvesen, G.S.11
-
9
-
-
4544288868
-
Activation of caspases-8 and -10 by FLIP(L)
-
Boatright K.M., Deis C., Denault J.B., Sutherlin D.P., Salvesen G.S. Activation of caspases-8 and -10 by FLIP(L). Biochem. J. 2004, 382:651-657.
-
(2004)
Biochem. J.
, vol.382
, pp. 651-657
-
-
Boatright, K.M.1
Deis, C.2
Denault, J.B.3
Sutherlin, D.P.4
Salvesen, G.S.5
-
10
-
-
77949911441
-
In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium
-
Boisset J.C., van Cappellen W., Andrieu-Soler C., Galjart N., Dzierzak E., Robin C. In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium. Nature 2010, 464:116-120.
-
(2010)
Nature
, vol.464
, pp. 116-120
-
-
Boisset, J.C.1
van Cappellen, W.2
Andrieu-Soler, C.3
Galjart, N.4
Dzierzak, E.5
Robin, C.6
-
11
-
-
79955484750
-
Mechanisms of necroptosis in T cells
-
Ch'en I.L., Tsau J.S., Molkentin J.D., Komatsu M., Hedrick S.M. Mechanisms of necroptosis in T cells. J. Exp. Med. 2011, 208:633-641.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 633-641
-
-
Ch'en, I.L.1
Tsau, J.S.2
Molkentin, J.D.3
Komatsu, M.4
Hedrick, S.M.5
-
12
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho Y.S., Challa S., Moquin D., Genga R., Ray T.D., Guildford M., Chan F.K. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 2009, 137:1112-1123.
-
(2009)
Cell
, vol.137
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
Genga, R.4
Ray, T.D.5
Guildford, M.6
Chan, F.K.7
-
13
-
-
18544383460
-
Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency
-
Chun H.J., Zheng L., Ahmad M., Wang J., Speirs C.K., Siegel R.M., Dale J.K., Puck J., Davis J., Hall C.G., et al. Pleiotropic defects in lymphocyte activation caused by caspase-8 mutations lead to human immunodeficiency. Nature 2002, 419:395-399.
-
(2002)
Nature
, vol.419
, pp. 395-399
-
-
Chun, H.J.1
Zheng, L.2
Ahmad, M.3
Wang, J.4
Speirs, C.K.5
Siegel, R.M.6
Dale, J.K.7
Puck, J.8
Davis, J.9
Hall, C.G.10
-
14
-
-
39449131430
-
T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20
-
Coornaert B., Baens M., Heyninck K., Bekaert T., Haegman M., Staal J., Sun L., Chen Z.J., Marynen P., Beyaert R. T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20. Nat. Immunol. 2008, 9:263-271.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 263-271
-
-
Coornaert, B.1
Baens, M.2
Heyninck, K.3
Bekaert, T.4
Haegman, M.5
Staal, J.6
Sun, L.7
Chen, Z.J.8
Marynen, P.9
Beyaert, R.10
-
15
-
-
42249102086
-
Identification of RIP1 kinase as a specific cellular target of necrostatins
-
Degterev A., Hitomi J., Germscheid M., Ch'en I.L., Korkina O., Teng X., Abbott D., Cuny G.D., Yuan C., Wagner G., et al. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nat. Chem. Biol. 2008, 4:313-321.
-
(2008)
Nat. Chem. Biol.
, vol.4
, pp. 313-321
-
-
Degterev, A.1
Hitomi, J.2
Germscheid, M.3
Ch'en, I.L.4
Korkina, O.5
Teng, X.6
Abbott, D.7
Cuny, G.D.8
Yuan, C.9
Wagner, G.10
-
16
-
-
43749122598
-
NF-kappaB suppression by the deubiquitinating enzyme Cezanne: a novel negative feedback loop in pro-inflammatory signaling
-
Enesa K., Zakkar M., Chaudhury H., Luong A., Rawlinson L., Mason J.C., Haskard D.O., Dean J.L., Evans P.C. NF-kappaB suppression by the deubiquitinating enzyme Cezanne: a novel negative feedback loop in pro-inflammatory signaling. J. Biol. Chem. 2008, 283:7036-7045.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 7036-7045
-
-
Enesa, K.1
Zakkar, M.2
Chaudhury, H.3
Luong, A.4
Rawlinson, L.5
Mason, J.C.6
Haskard, D.O.7
Dean, J.L.8
Evans, P.C.9
-
17
-
-
34548437549
-
Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain
-
Feng S., Yang Y., Mei Y., Ma L., Zhu D.E., Hoti N., Castanares M., Wu M. Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain. Cell. Signal. 2007, 19:2056-2067.
-
(2007)
Cell. Signal.
, vol.19
, pp. 2056-2067
-
-
Feng, S.1
Yang, Y.2
Mei, Y.3
Ma, L.4
Zhu, D.E.5
Hoti, N.6
Castanares, M.7
Wu, M.8
-
18
-
-
79960922705
-
CIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms
-
Feoktistova M., Geserick P., Kellert B., Dimitrova D.P., Langlais C., Hupe M., Cain K., Macfarlane M., Häcker G., Leverkus M. cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms. Mol. Cell 2011, 43:449-463.
-
(2011)
Mol. Cell
, vol.43
, pp. 449-463
-
-
Feoktistova, M.1
Geserick, P.2
Kellert, B.3
Dimitrova, D.P.4
Langlais, C.5
Hupe, M.6
Cain, K.7
Macfarlane, M.8
Häcker, G.9
Leverkus, M.10
-
19
-
-
33646688191
-
The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation
-
Golks A., Brenner D., Krammer P.H., Lavrik I.N. The c-FLIP-NH2 terminus (p22-FLIP) induces NF-kappaB activation. J. Exp. Med. 2006, 203:1295-1305.
-
(2006)
J. Exp. Med.
, vol.203
, pp. 1295-1305
-
-
Golks, A.1
Brenner, D.2
Krammer, P.H.3
Lavrik, I.N.4
-
20
-
-
58149201240
-
Cardiolipin provides an essential activating platform for caspase-8 on mitochondria
-
Gonzalvez F., Schug Z.T., Houtkooper R.H., MacKenzie E.D., Brooks D.G., Wanders R.J., Petit P.X., Vaz F.M., Gottlieb E. Cardiolipin provides an essential activating platform for caspase-8 on mitochondria. J. Cell Biol. 2008, 183:681-696.
-
(2008)
J. Cell Biol.
, vol.183
, pp. 681-696
-
-
Gonzalvez, F.1
Schug, Z.T.2
Houtkooper, R.H.3
MacKenzie, E.D.4
Brooks, D.G.5
Wanders, R.J.6
Petit, P.X.7
Vaz, F.M.8
Gottlieb, E.9
-
21
-
-
71149105333
-
Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction
-
Haas T.L., Emmerich C.H., Gerlach B., Schmukle A.C., Cordier S.M., Rieser E., Feltham R., Vince J., Warnken U., Wenger T., et al. Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction. Mol. Cell 2009, 36:831-844.
-
(2009)
Mol. Cell
, vol.36
, pp. 831-844
-
-
Haas, T.L.1
Emmerich, C.H.2
Gerlach, B.3
Schmukle, A.C.4
Cordier, S.M.5
Rieser, E.6
Feltham, R.7
Vince, J.8
Warnken, U.9
Wenger, T.10
-
22
-
-
2542449195
-
T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis
-
Hao Z., Hampel B., Yagita H., Rajewsky K. T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis. J. Exp. Med. 2004, 199:1355-1365.
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1355-1365
-
-
Hao, Z.1
Hampel, B.2
Yagita, H.3
Rajewsky, K.4
-
23
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
-
He S., Wang L., Miao L., Wang T., Du F., Zhao L., Wang X. Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. Cell 2009, 137:1100-1111.
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
Wang, T.4
Du, F.5
Zhao, L.6
Wang, X.7
-
24
-
-
33646264300
-
Caspase-8 promotes cell motility and calpain activity under nonapoptotic conditions
-
Helfer B., Boswell B.C., Finlay D., Cipres A., Vuori K., Bong Kang T., Wallach D., Dorfleutner A., Lahti J.M., Flynn D.C., Frisch S.M. Caspase-8 promotes cell motility and calpain activity under nonapoptotic conditions. Cancer Res. 2006, 66:4273-4278.
-
(2006)
Cancer Res.
, vol.66
, pp. 4273-4278
-
-
Helfer, B.1
Boswell, B.C.2
Finlay, D.3
Cipres, A.4
Vuori, K.5
Bong Kang, T.6
Wallach, D.7
Dorfleutner, A.8
Lahti, J.M.9
Flynn, D.C.10
Frisch, S.M.11
-
25
-
-
1542267804
-
Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification
-
Hosaka T., Biggs W.H., Tieu D., Boyer A.D., Varki N.M., Cavenee W.K., Arden K.C. Disruption of forkhead transcription factor (FOXO) family members in mice reveals their functional diversification. Proc. Natl. Acad. Sci. USA 2004, 101:2975-2980.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2975-2980
-
-
Hosaka, T.1
Biggs, W.H.2
Tieu, D.3
Boyer, A.D.4
Varki, N.M.5
Cavenee, W.K.6
Arden, K.C.7
-
26
-
-
0037397756
-
A function of Fas-associated death domain protein in cell cycle progression localized to a single amino acid at its C-terminal region
-
Hua Z.C., Sohn S.J., Kang C., Cado D., Winoto A. A function of Fas-associated death domain protein in cell cycle progression localized to a single amino acid at its C-terminal region. Immunity 2003, 18:513-521.
-
(2003)
Immunity
, vol.18
, pp. 513-521
-
-
Hua, Z.C.1
Sohn, S.J.2
Kang, C.3
Cado, D.4
Winoto, A.5
-
27
-
-
68349154339
-
Reconstitution of the death-inducing signaling complex reveals a substrate switch that determines CD95-mediated death or survival
-
Hughes M.A., Harper N., Butterworth M., Cain K., Cohen G.M., MacFarlane M. Reconstitution of the death-inducing signaling complex reveals a substrate switch that determines CD95-mediated death or survival. Mol. Cell 2009, 35:265-279.
-
(2009)
Mol. Cell
, vol.35
, pp. 265-279
-
-
Hughes, M.A.1
Harper, N.2
Butterworth, M.3
Cain, K.4
Cohen, G.M.5
MacFarlane, M.6
-
28
-
-
79953239980
-
SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis
-
Ikeda F., Deribe Y.L., Skånland S.S., Stieglitz B., Grabbe C., Franz-Wachtel M., van Wijk S.J., Goswami P., Nagy V., Terzic J., et al. SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis. Nature 2011, 471:637-641.
-
(2011)
Nature
, vol.471
, pp. 637-641
-
-
Ikeda, F.1
Deribe, Y.L.2
Skånland, S.S.3
Stieglitz, B.4
Grabbe, C.5
Franz-Wachtel, M.6
van Wijk, S.J.7
Goswami, P.8
Nagy, V.9
Terzic, J.10
-
29
-
-
0030800070
-
Inhibition of death receptor signals by cellular FLIP
-
Irmler M., Thome M., Hahne M., Schneider P., Hofmann K., Steiner V., Bodmer J.L., Schröter M., Burns K., Mattmann C., et al. Inhibition of death receptor signals by cellular FLIP. Nature 1997, 388:190-195.
-
(1997)
Nature
, vol.388
, pp. 190-195
-
-
Irmler, M.1
Thome, M.2
Hahne, M.3
Schneider, P.4
Hofmann, K.5
Steiner, V.6
Bodmer, J.L.7
Schröter, M.8
Burns, K.9
Mattmann, C.10
-
30
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
Kaiser W.J., Upton J.W., Long A.B., Livingston-Rosanoff D., Daley-Bauer L.P., Hakem R., Caspary T., Mocarski E.S. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 2011, 471:368-372.
-
(2011)
Nature
, vol.471
, pp. 368-372
-
-
Kaiser, W.J.1
Upton, J.W.2
Long, A.B.3
Livingston-Rosanoff, D.4
Daley-Bauer, L.P.5
Hakem, R.6
Caspary, T.7
Mocarski, E.S.8
-
31
-
-
4344560197
-
Caspase-8 serves both apoptotic and nonapoptotic roles
-
Kang T.B., Ben-Moshe T., Varfolomeev E.E., Pewzner-Jung Y., Yogev N., Jurewicz A., Waisman A., Brenner O., Haffner R., Gustafsson E., et al. Caspase-8 serves both apoptotic and nonapoptotic roles. J. Immunol. 2004, 173:2976-2984.
-
(2004)
J. Immunol.
, vol.173
, pp. 2976-2984
-
-
Kang, T.B.1
Ben-Moshe, T.2
Varfolomeev, E.E.3
Pewzner-Jung, Y.4
Yogev, N.5
Jurewicz, A.6
Waisman, A.7
Brenner, O.8
Haffner, R.9
Gustafsson, E.10
-
32
-
-
52149095957
-
Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice
-
Kang T.B., Oh G.S., Scandella E., Bolinger B., Ludewig B., Kovalenko A., Wallach D. Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice. J. Immunol. 2008, 181:2522-2532.
-
(2008)
J. Immunol.
, vol.181
, pp. 2522-2532
-
-
Kang, T.B.1
Oh, G.S.2
Scandella, E.3
Bolinger, B.4
Ludewig, B.5
Kovalenko, A.6
Wallach, D.7
-
33
-
-
1642386039
-
N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathway
-
Kataoka T., Tschopp J. N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathway. Mol. Cell. Biol. 2004, 24:2627-2636.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 2627-2636
-
-
Kataoka, T.1
Tschopp, J.2
-
34
-
-
48349125069
-
The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation
-
Kawadler H., Gantz M.A., Riley J.L., Yang X. The paracaspase MALT1 controls caspase-8 activation during lymphocyte proliferation. Mol. Cell 2008, 31:415-421.
-
(2008)
Mol. Cell
, vol.31
, pp. 415-421
-
-
Kawadler, H.1
Gantz, M.A.2
Riley, J.L.3
Yang, X.4
-
35
-
-
0033386808
-
Caspase activation is required for T cell proliferation
-
Kennedy N.J., Kataoka T., Tschopp J., Budd R.C. Caspase activation is required for T cell proliferation. J. Exp. Med. 1999, 190:1891-1896.
-
(1999)
J. Exp. Med.
, vol.190
, pp. 1891-1896
-
-
Kennedy, N.J.1
Kataoka, T.2
Tschopp, J.3
Budd, R.C.4
-
36
-
-
34249820757
-
TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death
-
Kim Y.S., Morgan M.J., Choksi S., Liu Z.G. TNF-induced activation of the Nox1 NADPH oxidase and its role in the induction of necrotic cell death. Mol. Cell 2007, 26:675-687.
-
(2007)
Mol. Cell
, vol.26
, pp. 675-687
-
-
Kim, Y.S.1
Morgan, M.J.2
Choksi, S.3
Liu, Z.G.4
-
37
-
-
54049100321
-
Spatial differences in active caspase-8 defines its role in T-cell activation versus cell death
-
Koenig A., Russell J.Q., Rodgers W.A., Budd R.C. Spatial differences in active caspase-8 defines its role in T-cell activation versus cell death. Cell Death Differ. 2008, 15:1701-1711.
-
(2008)
Cell Death Differ.
, vol.15
, pp. 1701-1711
-
-
Koenig, A.1
Russell, J.Q.2
Rodgers, W.A.3
Budd, R.C.4
-
38
-
-
70350484946
-
Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease
-
Kovalenko A., Kim J.C., Kang T.B., Rajput A., Bogdanov K., Dittrich-Breiholz O., Kracht M., Brenner O., Wallach D. Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease. J. Exp. Med. 2009, 206:2161-2177.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 2161-2177
-
-
Kovalenko, A.1
Kim, J.C.2
Kang, T.B.3
Rajput, A.4
Bogdanov, K.5
Dittrich-Breiholz, O.6
Kracht, M.7
Brenner, O.8
Wallach, D.9
-
39
-
-
34147165459
-
Essential role for caspase-8 in Toll-like receptors and NFkappaB signaling
-
Lemmers B., Salmena L., Bidère N., Su H., Matysiak-Zablocki E., Murakami K., Ohashi P.S., Jurisicova A., Lenardo M., Hakem R., Hakem A. Essential role for caspase-8 in Toll-like receptors and NFkappaB signaling. J. Biol. Chem. 2007, 282:7416-7423.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 7416-7423
-
-
Lemmers, B.1
Salmena, L.2
Bidère, N.3
Su, H.4
Matysiak-Zablocki, E.5
Murakami, K.6
Ohashi, P.S.7
Jurisicova, A.8
Lenardo, M.9
Hakem, R.10
Hakem, A.11
-
40
-
-
0033532386
-
The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis
-
Li Z.W., Chu W., Hu Y., Delhase M., Deerinck T., Ellisman M., Johnson R., Karin M. The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis. J. Exp. Med. 1999, 189:1839-1845.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1839-1845
-
-
Li, Z.W.1
Chu, W.2
Hu, Y.3
Delhase, M.4
Deerinck, T.5
Ellisman, M.6
Johnson, R.7
Karin, M.8
-
41
-
-
1642299768
-
Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation
-
Lin Y., Choksi S., Shen H.M., Yang Q.F., Hur G.M., Kim Y.S., Tran J.H., Nedospasov S.A., Liu Z.G. Tumor necrosis factor-induced nonapoptotic cell death requires receptor-interacting protein-mediated cellular reactive oxygen species accumulation. J. Biol. Chem. 2004, 279:10822-10828.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 10822-10828
-
-
Lin, Y.1
Choksi, S.2
Shen, H.M.3
Yang, Q.F.4
Hur, G.M.5
Kim, Y.S.6
Tran, J.H.7
Nedospasov, S.A.8
Liu, Z.G.9
-
42
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau O., Tschopp J. Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 2003, 114:181-190.
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
43
-
-
0034743199
-
NF-kappaB signals induce the expression of c-FLIP
-
Micheau O., Lens S., Gaide O., Alevizopoulos K., Tschopp J. NF-kappaB signals induce the expression of c-FLIP. Mol. Cell. Biol. 2001, 21:5299-5305.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 5299-5305
-
-
Micheau, O.1
Lens, S.2
Gaide, O.3
Alevizopoulos, K.4
Tschopp, J.5
-
44
-
-
0037160117
-
The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex
-
Micheau O., Thome M., Schneider P., Holler N., Tschopp J., Nicholson D.W., Briand C., Grütter M.G. The long form of FLIP is an activator of caspase-8 at the Fas death-inducing signaling complex. J. Biol. Chem. 2002, 277:45162-45171.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 45162-45171
-
-
Micheau, O.1
Thome, M.2
Schneider, P.3
Holler, N.4
Tschopp, J.5
Nicholson, D.W.6
Briand, C.7
Grütter, M.G.8
-
45
-
-
0032472916
-
A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes
-
Newton K., Harris A.W., Bath M.L., Smith K.G., Strasser A. A dominant interfering mutant of FADD/MORT1 enhances deletion of autoreactive thymocytes and inhibits proliferation of mature T lymphocytes. EMBO J. 1998, 17:706-718.
-
(1998)
EMBO J.
, vol.17
, pp. 706-718
-
-
Newton, K.1
Harris, A.W.2
Bath, M.L.3
Smith, K.G.4
Strasser, A.5
-
46
-
-
0842304221
-
Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4
-
Newton K., Sun X., Dixit V.M. Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4. Mol. Cell. Biol. 2004, 24:1464-1469.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 1464-1469
-
-
Newton, K.1
Sun, X.2
Dixit, V.M.3
-
47
-
-
84856160569
-
Caspase 8 inhibits programmed necrosis by processing CYLD
-
in press
-
O'Donnell M.A., Perez-Jimenez E., Oberst A., Ng A., Massoumi R., Xavier R., Green D.R., Ting A.T. Caspase 8 inhibits programmed necrosis by processing CYLD. Nat. Cell Biol. 2011, in press.
-
(2011)
Nat. Cell Biol.
-
-
O'Donnell, M.A.1
Perez-Jimenez, E.2
Oberst, A.3
Ng, A.4
Massoumi, R.5
Xavier, R.6
Green, D.R.7
Ting, A.T.8
-
48
-
-
77952784381
-
Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation
-
Oberst A., Pop C., Tremblay A.G., Blais V., Denault J.B., Salvesen G.S., Green D.R. Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation. J. Biol. Chem. 2010, 285:16632-16642.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 16632-16642
-
-
Oberst, A.1
Pop, C.2
Tremblay, A.G.3
Blais, V.4
Denault, J.B.5
Salvesen, G.S.6
Green, D.R.7
-
49
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
Oberst A., Dillon C.P., Weinlich R., McCormick L.L., Fitzgerald P., Pop C., Hakem R., Salvesen G.S., Green D.R. Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 2011, 471:363-367.
-
(2011)
Nature
, vol.471
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
McCormick, L.L.4
Fitzgerald, P.5
Pop, C.6
Hakem, R.7
Salvesen, G.S.8
Green, D.R.9
-
50
-
-
67649213892
-
Down-regulation of FoxO-dependent c-FLIP expression mediates TRAIL-induced apoptosis in activated hepatic stellate cells
-
Park S.J., Sohn H.Y., Yoon J., Park S.I. Down-regulation of FoxO-dependent c-FLIP expression mediates TRAIL-induced apoptosis in activated hepatic stellate cells. Cell. Signal. 2009, 21:1495-1503.
-
(2009)
Cell. Signal.
, vol.21
, pp. 1495-1503
-
-
Park, S.J.1
Sohn, H.Y.2
Yoon, J.3
Park, S.I.4
-
51
-
-
78751487532
-
FLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity
-
Pop C., Oberst A., Drag M., Van Raam B.J., Riedl S.J., Green D.R., Salvesen G.S. FLIP(L) induces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity. Biochem. J. 2011, 433:447-457.
-
(2011)
Biochem. J.
, vol.433
, pp. 447-457
-
-
Pop, C.1
Oberst, A.2
Drag, M.3
Van Raam, B.J.4
Riedl, S.J.5
Green, D.R.6
Salvesen, G.S.7
-
52
-
-
20144381544
-
Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death
-
Pyo J.O., Jang M.H., Kwon Y.K., Lee H.J., Jun J.I., Woo H.N., Cho D.H., Choi B., Lee H., Kim J.H., et al. Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death. J. Biol. Chem. 2005, 280:20722-20729.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20722-20729
-
-
Pyo, J.O.1
Jang, M.H.2
Kwon, Y.K.3
Lee, H.J.4
Jun, J.I.5
Woo, H.N.6
Cho, D.H.7
Choi, B.8
Lee, H.9
Kim, J.H.10
-
53
-
-
79952770123
-
RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein
-
Rajput A., Kovalenko A., Bogdanov K., Yang S.H., Kang T.B., Kim J.C., Du J., Wallach D. RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein. Immunity 2011, 34:340-351.
-
(2011)
Immunity
, vol.34
, pp. 340-351
-
-
Rajput, A.1
Kovalenko, A.2
Bogdanov, K.3
Yang, S.H.4
Kang, T.B.5
Kim, J.C.6
Du, J.7
Wallach, D.8
-
54
-
-
33846922252
-
Caspase-8 prevents sustained activation of NF-kappaB in monocytes undergoing macrophagic differentiation
-
Rébé C., Cathelin S., Launay S., Filomenko R., Prévotat L., L'Ollivier C., Gyan E., Micheau O., Grant S., Dubart-Kupperschmitt A., et al. Caspase-8 prevents sustained activation of NF-kappaB in monocytes undergoing macrophagic differentiation. Blood 2007, 109:1442-1450.
-
(2007)
Blood
, vol.109
, pp. 1442-1450
-
-
Rébé, C.1
Cathelin, S.2
Launay, S.3
Filomenko, R.4
Prévotat, L.5
L'Ollivier, C.6
Gyan, E.7
Micheau, O.8
Grant, S.9
Dubart-Kupperschmitt, A.10
-
55
-
-
68249113997
-
DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB
-
Rebsamen M., Heinz L.X., Meylan E., Michallet M.C., Schroder K., Hofmann K., Vazquez J., Benedict C.A., Tschopp J. DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB. EMBO Rep. 2009, 10:916-922.
-
(2009)
EMBO Rep.
, vol.10
, pp. 916-922
-
-
Rebsamen, M.1
Heinz, L.X.2
Meylan, E.3
Michallet, M.C.4
Schroder, K.5
Hofmann, K.6
Vazquez, J.7
Benedict, C.A.8
Tschopp, J.9
-
56
-
-
0029006893
-
Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity
-
Rieux-Laucat F., Le Deist F., Hivroz C., Roberts I.A., Debatin K.M., Fischer A., de Villartay J.P. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. Science 1995, 268:1347-1349.
-
(1995)
Science
, vol.268
, pp. 1347-1349
-
-
Rieux-Laucat, F.1
Le Deist, F.2
Hivroz, C.3
Roberts, I.A.4
Debatin, K.M.5
Fischer, A.6
de Villartay, J.P.7
-
57
-
-
0033598145
-
Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis
-
Rytömaa M., Martins L.M., Downward J. Involvement of FADD and caspase-8 signalling in detachment-induced apoptosis. Curr. Biol. 1999, 9:1043-1046.
-
(1999)
Curr. Biol.
, vol.9
, pp. 1043-1046
-
-
Rytömaa, M.1
Martins, L.M.2
Downward, J.3
-
58
-
-
69749117596
-
Structure of the Fas/FADD complex: a conditional death domain complex mediating signaling by receptor clustering
-
Salvesen G.S., Riedl S.J. Structure of the Fas/FADD complex: a conditional death domain complex mediating signaling by receptor clustering. Cell Cycle 2009, 8:2723-2727.
-
(2009)
Cell Cycle
, vol.8
, pp. 2723-2727
-
-
Salvesen, G.S.1
Riedl, S.J.2
-
59
-
-
0033103523
-
Caspase-8 is required for cell death induced by expanded polyglutamine repeats
-
Sánchez I., Xu C.J., Juo P., Kakizaka A., Blenis J., Yuan J. Caspase-8 is required for cell death induced by expanded polyglutamine repeats. Neuron 1999, 22:623-633.
-
(1999)
Neuron
, vol.22
, pp. 623-633
-
-
Sánchez, I.1
Xu, C.J.2
Juo, P.3
Kakizaka, A.4
Blenis, J.5
Yuan, J.6
-
60
-
-
0029001244
-
Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation
-
Sato T.N., Tozawa Y., Deutsch U., Wolburg-Buchholz K., Fujiwara Y., Gendron-Maguire M., Gridley T., Wolburg H., Risau W., Qin Y. Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation. Nature 1995, 376:70-74.
-
(1995)
Nature
, vol.376
, pp. 70-74
-
-
Sato, T.N.1
Tozawa, Y.2
Deutsch, U.3
Wolburg-Buchholz, K.4
Fujiwara, Y.5
Gendron-Maguire, M.6
Gridley, T.7
Wolburg, H.8
Risau, W.9
Qin, Y.10
-
61
-
-
0036739041
-
Caspase inhibitors induce a switch from apoptotic to proinflammatory signaling in CD95-stimulated T lymphocytes
-
Scheller C., Sopper S., Ehrhardt C., Flory E., Chen P., Koutsilieri E., Ludwig S., ter Meulen V., Jassoy C. Caspase inhibitors induce a switch from apoptotic to proinflammatory signaling in CD95-stimulated T lymphocytes. Eur. J. Immunol. 2002, 32:2471-2480.
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 2471-2480
-
-
Scheller, C.1
Sopper, S.2
Ehrhardt, C.3
Flory, E.4
Chen, P.5
Koutsilieri, E.6
Ludwig, S.7
ter Meulen, V.8
Jassoy, C.9
-
62
-
-
77951476070
-
Extreme lymphoproliferative disease and fatal autoimmune thrombocytopenia in FasL and TRAIL double-deficient mice
-
Sedger L.M., Katewa A., Pettersen A.K., Osvath S.R., Farrell G.C., Stewart G.J., Bendall L.J., Alexander S.I. Extreme lymphoproliferative disease and fatal autoimmune thrombocytopenia in FasL and TRAIL double-deficient mice. Blood 2010, 115:3258-3268.
-
(2010)
Blood
, vol.115
, pp. 3258-3268
-
-
Sedger, L.M.1
Katewa, A.2
Pettersen, A.K.3
Osvath, S.R.4
Farrell, G.C.5
Stewart, G.J.6
Bendall, L.J.7
Alexander, S.I.8
-
63
-
-
37549062115
-
Caspase-8 interacts with the p85 subunit of phosphatidylinositol 3-kinase to regulate cell adhesion and motility
-
Senft J., Helfer B., Frisch S.M. Caspase-8 interacts with the p85 subunit of phosphatidylinositol 3-kinase to regulate cell adhesion and motility. Cancer Res. 2007, 67:11505-11509.
-
(2007)
Cancer Res.
, vol.67
, pp. 11505-11509
-
-
Senft, J.1
Helfer, B.2
Frisch, S.M.3
-
64
-
-
0029834497
-
CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease
-
Smith K.G., Strasser A., Vaux D.L. CrmA expression in T lymphocytes of transgenic mice inhibits CD95 (Fas/APO-1)-transduced apoptosis, but does not cause lymphadenopathy or autoimmune disease. EMBO J. 1996, 15:5167-5176.
-
(1996)
EMBO J.
, vol.15
, pp. 5167-5176
-
-
Smith, K.G.1
Strasser, A.2
Vaux, D.L.3
-
65
-
-
0037009370
-
Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8
-
Sprick M.R., Rieser E., Stahl H., Grosse-Wilde A., Weigand M.A., Walczak H. Caspase-10 is recruited to and activated at the native TRAIL and CD95 death-inducing signalling complexes in a FADD-dependent manner but can not functionally substitute caspase-8. EMBO J. 2002, 21:4520-4530.
-
(2002)
EMBO J.
, vol.21
, pp. 4520-4530
-
-
Sprick, M.R.1
Rieser, E.2
Stahl, H.3
Grosse-Wilde, A.4
Weigand, M.A.5
Walczak, H.6
-
66
-
-
79955592698
-
T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1
-
Staal J., Driege Y., Bekaert T., Demeyer A., Muyllaert D., Van Damme P., Gevaert K., Beyaert R. T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1. EMBO J. 2011, 30:1742-1752.
-
(2011)
EMBO J.
, vol.30
, pp. 1742-1752
-
-
Staal, J.1
Driege, Y.2
Bekaert, T.3
Demeyer, A.4
Muyllaert, D.5
Van Damme, P.6
Gevaert, K.7
Beyaert, R.8
-
67
-
-
0035851912
-
Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins
-
Stupack D.G., Puente X.S., Boutsaboualoy S., Storgard C.M., Cheresh D.A. Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins. J. Cell Biol. 2001, 155:459-470.
-
(2001)
J. Cell Biol.
, vol.155
, pp. 459-470
-
-
Stupack, D.G.1
Puente, X.S.2
Boutsaboualoy, S.3
Storgard, C.M.4
Cheresh, D.A.5
-
68
-
-
20044368626
-
Requirement for caspase-8 in NF-kappaB activation by antigen receptor
-
Su H., Bidère N., Zheng L., Cubre A., Sakai K., Dale J., Salmena L., Hakem R., Straus S., Lenardo M. Requirement for caspase-8 in NF-kappaB activation by antigen receptor. Science 2005, 307:1465-1468.
-
(2005)
Science
, vol.307
, pp. 1465-1468
-
-
Su, H.1
Bidère, N.2
Zheng, L.3
Cubre, A.4
Sakai, K.5
Dale, J.6
Salmena, L.7
Hakem, R.8
Straus, S.9
Lenardo, M.10
-
69
-
-
0030480322
-
Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis
-
Suri C., Jones P.F., Patan S., Bartunkova S., Maisonpierre P.C., Davis S., Sato T.N., Yancopoulos G.D. Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis. Cell 1996, 87:1171-1180.
-
(1996)
Cell
, vol.87
, pp. 1171-1180
-
-
Suri, C.1
Jones, P.F.2
Patan, S.3
Bartunkova, S.4
Maisonpierre, P.C.5
Davis, S.6
Sato, T.N.7
Yancopoulos, G.D.8
-
70
-
-
0028223847
-
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
-
Takahashi T., Tanaka M., Brannan C.I., Jenkins N.A., Copeland N.G., Suda T., Nagata S. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 1994, 76:969-976.
-
(1994)
Cell
, vol.76
, pp. 969-976
-
-
Takahashi, T.1
Tanaka, M.2
Brannan, C.I.3
Jenkins, N.A.4
Copeland, N.G.5
Suda, T.6
Nagata, S.7
-
71
-
-
0033119952
-
Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice
-
Tanaka M., Fuentes M.E., Yamaguchi K., Durnin M.H., Dalrymple S.A., Hardy K.L., Goeddel D.V. Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice. Immunity 1999, 10:421-429.
-
(1999)
Immunity
, vol.10
, pp. 421-429
-
-
Tanaka, M.1
Fuentes, M.E.2
Yamaguchi, K.3
Durnin, M.H.4
Dalrymple, S.A.5
Hardy, K.L.6
Goeddel, D.V.7
-
72
-
-
79960921946
-
The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs
-
Tenev T., Bianchi K., Darding M., Broemer M., Langlais C., Wallberg F., Zachariou A., Lopez J., Macfarlane M., Cain K., Meier P. The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs. Mol. Cell 2011, 43:432-448.
-
(2011)
Mol. Cell
, vol.43
, pp. 432-448
-
-
Tenev, T.1
Bianchi, K.2
Darding, M.3
Broemer, M.4
Langlais, C.5
Wallberg, F.6
Zachariou, A.7
Lopez, J.8
Macfarlane, M.9
Cain, K.10
Meier, P.11
-
73
-
-
59649103156
-
Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation
-
Tokunaga F., Sakata S., Saeki Y., Satomi Y., Kirisako T., Kamei K., Nakagawa T., Kato M., Murata S., Yamaoka S., et al. Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation. Nat. Cell Biol. 2009, 11:123-132.
-
(2009)
Nat. Cell Biol.
, vol.11
, pp. 123-132
-
-
Tokunaga, F.1
Sakata, S.2
Saeki, Y.3
Satomi, Y.4
Kirisako, T.5
Kamei, K.6
Nakagawa, T.7
Kato, M.8
Murata, S.9
Yamaoka, S.10
-
74
-
-
79953237668
-
SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex
-
Tokunaga F., Nakagawa T., Nakahara M., Saeki Y., Taniguchi M., Sakata S., Tanaka K., Nakano H., Iwai K. SHARPIN is a component of the NF-κB-activating linear ubiquitin chain assembly complex. Nature 2011, 471:633-636.
-
(2011)
Nature
, vol.471
, pp. 633-636
-
-
Tokunaga, F.1
Nakagawa, T.2
Nakahara, M.3
Saeki, Y.4
Taniguchi, M.5
Sakata, S.6
Tanaka, K.7
Nakano, H.8
Iwai, K.9
-
76
-
-
1542289739
-
Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD
-
Vanden Berghe T., van Loo G., Saelens X., Van Gurp M., Brouckaert G., Kalai M., Declercq W., Vandenabeele P. Differential signaling to apoptotic and necrotic cell death by Fas-associated death domain protein FADD. J. Biol. Chem. 2004, 279:7925-7933.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 7925-7933
-
-
Vanden Berghe, T.1
van Loo, G.2
Saelens, X.3
Van Gurp, M.4
Brouckaert, G.5
Kalai, M.6
Declercq, W.7
Vandenabeele, P.8
-
77
-
-
0032143986
-
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally
-
Varfolomeev E.E., Schuchmann M., Luria V., Chiannilkulchai N., Beckmann J.S., Mett I.L., Rebrikov D., Brodianski V.M., Kemper O.C., Kollet O., et al. Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally. Immunity 1998, 9:267-276.
-
(1998)
Immunity
, vol.9
, pp. 267-276
-
-
Varfolomeev, E.E.1
Schuchmann, M.2
Luria, V.3
Chiannilkulchai, N.4
Beckmann, J.S.5
Mett, I.L.6
Rebrikov, D.7
Brodianski, V.M.8
Kemper, O.C.9
Kollet, O.10
-
78
-
-
36048999753
-
IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis
-
Varfolomeev E., Blankenship J.W., Wayson S.M., Fedorova A.V., Kayagaki N., Garg P., Zobel K., Dynek J.N., Elliott L.O., Wallweber H.J., et al. IAP antagonists induce autoubiquitination of c-IAPs, NF-kappaB activation, and TNFalpha-dependent apoptosis. Cell 2007, 131:669-681.
-
(2007)
Cell
, vol.131
, pp. 669-681
-
-
Varfolomeev, E.1
Blankenship, J.W.2
Wayson, S.M.3
Fedorova, A.V.4
Kayagaki, N.5
Garg, P.6
Zobel, K.7
Dynek, J.N.8
Elliott, L.O.9
Wallweber, H.J.10
-
79
-
-
0032482169
-
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor
-
Vercammen D., Beyaert R., Denecker G., Goossens V., Van Loo G., Declercq W., Grooten J., Fiers W., Vandenabeele P. Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. J. Exp. Med. 1998, 187:1477-1485.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1477-1485
-
-
Vercammen, D.1
Beyaert, R.2
Denecker, G.3
Goossens, V.4
Van Loo, G.5
Declercq, W.6
Grooten, J.7
Fiers, W.8
Vandenabeele, P.9
-
80
-
-
0032482169
-
Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor
-
Vercammen D., Beyaert R., Denecker G., Goossens V., Van Loo G., Declercq W., Grooten J., Fiers W., Vandenabeele P. Inhibition of caspases increases the sensitivity of L929 cells to necrosis mediated by tumor necrosis factor. J. Exp. Med. 1998, 187:1477-1485.
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1477-1485
-
-
Vercammen, D.1
Beyaert, R.2
Denecker, G.3
Goossens, V.4
Van Loo, G.5
Declercq, W.6
Grooten, J.7
Fiers, W.8
Vandenabeele, P.9
-
81
-
-
36148954336
-
IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis
-
Vince J.E., Wong W.W., Khan N., Feltham R., Chau D., Ahmed A.U., Benetatos C.A., Chunduru S.K., Condon S.M., McKinlay M., et al. IAP antagonists target cIAP1 to induce TNFalpha-dependent apoptosis. Cell 2007, 131:682-693.
-
(2007)
Cell
, vol.131
, pp. 682-693
-
-
Vince, J.E.1
Wong, W.W.2
Khan, N.3
Feltham, R.4
Chau, D.5
Ahmed, A.U.6
Benetatos, C.A.7
Chunduru, S.K.8
Condon, S.M.9
McKinlay, M.10
-
82
-
-
43049152912
-
TNF-alpha induces two distinct caspase-8 activation pathways
-
Wang L., Du F., Wang X. TNF-alpha induces two distinct caspase-8 activation pathways. Cell 2008, 133:693-703.
-
(2008)
Cell
, vol.133
, pp. 693-703
-
-
Wang, L.1
Du, F.2
Wang, X.3
-
83
-
-
0026568919
-
Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
-
Watanabe-Fukunaga R., Brannan C.I., Copeland N.G., Jenkins N.A., Nagata S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 1992, 356:314-317.
-
(1992)
Nature
, vol.356
, pp. 314-317
-
-
Watanabe-Fukunaga, R.1
Brannan, C.I.2
Copeland, N.G.3
Jenkins, N.A.4
Nagata, S.5
-
84
-
-
62849093368
-
Death receptor signal transducers: nodes of coordination in immune signaling networks
-
Wilson N.S., Dixit V., Ashkenazi A. Death receptor signal transducers: nodes of coordination in immune signaling networks. Nat. Immunol. 2009, 10:348-355.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 348-355
-
-
Wilson, N.S.1
Dixit, V.2
Ashkenazi, A.3
-
85
-
-
76749132616
-
RIPK1 is not essential for TNFR1-induced activation of NF-kappaB
-
Wong W.W., Gentle I.E., Nachbur U., Anderton H., Vaux D.L., Silke J. RIPK1 is not essential for TNFR1-induced activation of NF-kappaB. Cell Death Differ. 2010, 17:482-487.
-
(2010)
Cell Death Differ.
, vol.17
, pp. 482-487
-
-
Wong, W.W.1
Gentle, I.E.2
Nachbur, U.3
Anderton, H.4
Vaux, D.L.5
Silke, J.6
-
86
-
-
7144263731
-
FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis
-
Yeh W.C., Pompa J.L., McCurrach M.E., Shu H.B., Elia A.J., Shahinian A., Ng M., Wakeham A., Khoo W., Mitchell K., et al. FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 1998, 279:1954-1958.
-
(1998)
Science
, vol.279
, pp. 1954-1958
-
-
Yeh, W.C.1
Pompa, J.L.2
McCurrach, M.E.3
Shu, H.B.4
Elia, A.J.5
Shahinian, A.6
Ng, M.7
Wakeham, A.8
Khoo, W.9
Mitchell, K.10
-
87
-
-
0033662341
-
Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development
-
Yeh W.C., Itie A., Elia A.J., Ng M., Shu H.B., Wakeham A., Mirtsos C., Suzuki N., Bonnard M., Goeddel D.V., Mak T.W. Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. Immunity 2000, 12:633-642.
-
(2000)
Immunity
, vol.12
, pp. 633-642
-
-
Yeh, W.C.1
Itie, A.2
Elia, A.J.3
Ng, M.4
Shu, H.B.5
Wakeham, A.6
Mirtsos, C.7
Suzuki, N.8
Bonnard, M.9
Goeddel, D.V.10
Mak, T.W.11
-
88
-
-
0035839640
-
FADD-deficient T cells exhibit a disaccord in regulation of the cell cycle machinery
-
Zhang J., Kabra N.H., Cado D., Kang C., Winoto A. FADD-deficient T cells exhibit a disaccord in regulation of the cell cycle machinery. J. Biol. Chem. 2001, 276:29815-29818.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 29815-29818
-
-
Zhang, J.1
Kabra, N.H.2
Cado, D.3
Kang, C.4
Winoto, A.5
-
89
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang D.W., Shao J., Lin J., Zhang N., Lu B.J., Lin S.C., Dong M.Q., Han J. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 2009, 325:332-336.
-
(2009)
Science
, vol.325
, pp. 332-336
-
-
Zhang, D.W.1
Shao, J.2
Lin, J.3
Zhang, N.4
Lu, B.J.5
Lin, S.C.6
Dong, M.Q.7
Han, J.8
-
90
-
-
79952780505
-
Functional complementation between FADD and RIP1 in embryos and lymphocytes
-
Zhang H., Zhou X., McQuade T., Li J., Chan F.K., Zhang J. Functional complementation between FADD and RIP1 in embryos and lymphocytes. Nature 2011, 471:373-376.
-
(2011)
Nature
, vol.471
, pp. 373-376
-
-
Zhang, H.1
Zhou, X.2
McQuade, T.3
Li, J.4
Chan, F.K.5
Zhang, J.6
|