Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis

Biochemical Journal

Volumn 383, Issue 1, 2004, Pages 101-109

  Li, Yanmin ^a   Johnson, Nicholas ^a   Capano, Michela ^a   Edwards, Mina ^a   Crompton, Martin ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Apoptosis; Cyclophilin D; Mitochondria; Necrosis; Permeability transition

Indexed keywords

BIOLOGICAL ORGANS; ENZYMES; MAGNETIC PERMEABILITY; PORE SIZE;

ANTIPORTER; MITOCHONDRIAL PERMEABILITY; NUCLEOTIDES;

BIOMEDICAL ENGINEERING;

ADENINE NUCLEOTIDE TRANSLOCASE; ANTIPORTER; CALCIUM ION; CIS TRANS ISOMERASE; CYCLOPHILIN; CYCLOPHILIN D; CYCLOSPORIN A; NITRIC OXIDE; STAUROSPORINE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CELL DAMAGE; CELL DEATH; CELL LINE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG EFFECT; DRUG INHIBITION; EXTRACELLULAR MATRIX; GENE; GENE OVEREXPRESSION; MEMBRANE PERMEABILITY; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NERVE CELL; NONHUMAN; OXIDATIVE STRESS; PERMEABILITY; PERMEABILITY TRANSITION; PRIORITY JOURNAL; RAT;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; CASPASES; CELL LINE; CYCLOPHILINS; CYCLOSPORINE; FLUORESCENT DYES; INTRACELLULAR MEMBRANES; ION CHANNELS; MITOCHONDRIA; MITOCHONDRIAL ADP, ATP TRANSLOCASES; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; MOLECULAR SEQUENCE DATA; NECROSIS; ONIUM COMPOUNDS; ORGANOMETALLIC COMPOUNDS; ORGANOPHOSPHORUS COMPOUNDS; PERMEABILITY; RATS; RECOMBINANT PROTEINS;

ANIMALIA;

EID: 6344287496     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20040669     Document Type: Article

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