Oxidative modification sensitizes mitochondrial apoptosis-inducing factor to calpain-mediated processing

Free Radical Biology and Medicine

Volumn 48, Issue 6, 2010, Pages 791-797

  Norberg, Erik ^a   Gogvadze, Vladimir ^a   Vakifahmetoglu, Helin ^a   Orrenius, Sten ^a   Zhivotovsky, Boris ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Apoptosis; Apoptosis inducing factor; Calcium; Calpain; Carbonylation; Free radicals; Mitochondria; Reactive oxygen species

Indexed keywords

ANTIOXIDANT; APOPTOSIS INDUCING FACTOR; CALCIUM ION; CALPAIN; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; PYRIMIDINE NUCLEOTIDE; REACTIVE OXYGEN METABOLITE; STAUROSPORINE;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CHELATION; CONTROLLED STUDY; CYTOSOL; HUMAN; HUMAN CELL; MITOCHONDRIAL RESPIRATION; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROTEIN CARBONYLATION; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN NUCLEIC ACID INTERACTION; PROTEIN PROCESSING; PROTEIN SECRETION;

ANIMALS; APOPTOSIS INDUCING FACTOR; CALPAIN; HELA CELLS; HUMANS; MITOCHONDRIA, LIVER; OXIDATION-REDUCTION; PYRIDINES; RATS; REACTIVE OXYGEN SPECIES; SENSITIVITY AND SPECIFICITY; TIME FACTORS; TUMOR CELLS, CULTURED;

EID: 76049095102     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2009.12.020     Document Type: Article

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