-
1
-
-
49349100454
-
Caenorhabditis elegans drp-1 and fis-2 regulate distinct cell-death execution pathways downstream of ced-3 and independent of ced-9
-
D.G. Breckenridge, B.H. Kang, D. Kokel, S. Mitani, L.A. Staehelin, and D. Xue Caenorhabditis elegans drp-1 and fis-2 regulate distinct cell-death execution pathways downstream of ced-3 and independent of ced-9 Mol. Cell 31 2008 586 597
-
(2008)
Mol. Cell
, vol.31
, pp. 586-597
-
-
Breckenridge, D.G.1
Kang, B.H.2
Kokel, D.3
Mitani, S.4
Staehelin, L.A.5
Xue, D.6
-
2
-
-
38849099158
-
Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization
-
DOI 10.1016/j.devcel.2007.11.019, PII S1534580707004753
-
A. Cassidy-Stone, J.E. Chipuk, E. Ingerman, C. Song, C. Yoo, T. Kuwana, M.J. Kurth, J.T. Shaw, J.E. Hinshaw, D.R. Green, and J. Nunnari Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization Dev. Cell 14 2008 193 204 (Pubitemid 351189177)
-
(2008)
Developmental Cell
, vol.14
, Issue.2
, pp. 193-204
-
-
Cassidy-Stone, A.1
Chipuk, J.E.2
Ingerman, E.3
Song, C.4
Yoo, C.5
Kuwana, T.6
Kurth, M.J.7
Shaw, J.T.8
Hinshaw, J.E.9
Green, D.R.10
Nunnari, J.11
-
3
-
-
34547611925
-
Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology
-
DOI 10.1074/jbc.C700083200
-
C.R. Chang, and C. Blackstone Cyclic AMP-dependent protein kinase phosphorylation of Drp1 regulates its GTPase activity and mitochondrial morphology J. Biol. Chem. 282 2007 21583 21587 (Pubitemid 47195725)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.30
, pp. 21583-21587
-
-
Chang, C.-R.1
Blackstone, C.2
-
4
-
-
64249133725
-
S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury
-
D.H. Cho, T. Nakamura, J. Fang, P. Cieplak, A. Godzik, Z. Gu, and S.A. Lipton S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury Science 324 2009 102 105
-
(2009)
Science
, vol.324
, pp. 102-105
-
-
Cho, D.H.1
Nakamura, T.2
Fang, J.3
Cieplak, P.4
Godzik, A.5
Gu, Z.6
Lipton, S.A.7
-
5
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Y.S. Cho, S. Challa, D. Moquin, R. Genga, T.D. Ray, M. Guildford, and F.K. Chan Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation Cell 137 2009 1112 1123
-
(2009)
Cell
, vol.137
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
Genga, R.4
Ray, T.D.5
Guildford, M.6
Chan, F.K.7
-
6
-
-
34848840991
-
Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death
-
DOI 10.1038/sj.embor.7401062, PII 7401062
-
J.T. Cribbs, and S. Strack Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death EMBO Rep. 8 2007 939 944 (Pubitemid 47500477)
-
(2007)
EMBO Reports
, vol.8
, Issue.10
, pp. 939-944
-
-
Cribbs, J.T.1
Strack, S.2
-
7
-
-
67650638892
-
RIP kinases at the crossroads of cell death and survival
-
W. Declercq, T. Vanden Berghe, and P. Vandenabeele RIP kinases at the crossroads of cell death and survival Cell 138 2009 229 232
-
(2009)
Cell
, vol.138
, pp. 229-232
-
-
Declercq, W.1
Vanden Berghe, T.2
Vandenabeele, P.3
-
8
-
-
42249102086
-
Identification of RIP1 kinase as a specific cellular target of necrostatins
-
DOI 10.1038/nchembio.83, PII NCHEMBIO83
-
A. Degterev, J. Hitomi, M. Germscheid, I.L. Ch'en, O. Korkina, X. Teng, D. Abbott, G.D. Cuny, C. Yuan, and G. Wagner Identification of RIP1 kinase as a specific cellular target of necrostatins Nat. Chem. Biol. 4 2008 313 321 (Pubitemid 351550892)
-
(2008)
Nature Chemical Biology
, vol.4
, Issue.5
, pp. 313-321
-
-
Degterev, A.1
Hitomi, J.2
Germscheid, M.3
Ch'en, I.L.4
Korkina, O.5
Teng, X.6
Abbott, D.7
Cuny, G.D.8
Yuan, C.9
Wagner, G.10
Hedrick, S.M.11
Gerber, S.A.12
Lugovskoy, A.13
Yuan, J.14
-
9
-
-
0035487808
-
The Role of Dynamin-Related Protein 1, a Mediator of Mitochondrial Fission, in Apoptosis
-
DOI 10.1016/S1534-5807(01)00055-7, PII S1534580701000557
-
S. Frank, B. Gaume, E.S. Bergmann-Leitner, W.W. Leitner, E.G. Robert, F. Catez, C.L. Smith, and R.J. Youle The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis Dev. Cell 1 2001 515 525 (Pubitemid 33586103)
-
(2001)
Developmental Cell
, vol.1
, Issue.4
, pp. 515-525
-
-
Frank, S.1
Gaume, B.2
Bergmann-Leitner, E.S.3
Leitner, W.W.4
Robert, E.G.5
Catez, F.6
Smith, C.L.7
Youle, R.J.8
-
10
-
-
66749183275
-
Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha
-
S. He, L. Wang, L. Miao, T. Wang, F. Du, L. Zhao, and X. Wang Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha Cell 137 2009 1100 1111
-
(2009)
Cell
, vol.137
, pp. 1100-1111
-
-
He, S.1
Wang, L.2
Miao, L.3
Wang, T.4
Du, F.5
Zhao, L.6
Wang, X.7
-
11
-
-
5944233768
-
Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule
-
N. Holler, R. Zaru, O. Micheau, M. Thome, A. Attinger, S. Valitutti, J.L. Bodmer, P. Schneider, B. Seed, and J. Tschopp Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule Nat. Immunol. 1 2000 489 495
-
(2000)
Nat. Immunol.
, vol.1
, pp. 489-495
-
-
Holler, N.1
Zaru, R.2
Micheau, O.3
Thome, M.4
Attinger, A.5
Valitutti, S.6
Bodmer, J.L.7
Schneider, P.8
Seed, B.9
Tschopp, J.10
-
12
-
-
78650716707
-
The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila
-
Y. Imai, T. Kanao, T. Sawada, Y. Kobayashi, Y. Moriwaki, Y. Ishida, K. Takeda, H. Ichijo, B. Lu, and R. Takahashi The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila PLoS Genet. 6 2010 e1001229
-
(2010)
PLoS Genet.
, vol.6
, pp. 1001229
-
-
Imai, Y.1
Kanao, T.2
Sawada, T.3
Kobayashi, Y.4
Moriwaki, Y.5
Ishida, Y.6
Takeda, K.7
Ichijo, H.8
Lu, B.9
Takahashi, R.10
-
13
-
-
13944278072
-
DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans
-
DOI 10.1038/nature03316
-
R. Jagasia, P. Grote, B. Westermann, and B. Conradt DRP-1-mediated mitochondrial fragmentation during EGL-1-induced cell death in C. elegans Nature 433 2005 754 760 (Pubitemid 40292985)
-
(2005)
Nature
, vol.433
, Issue.7027
, pp. 754-760
-
-
Jagasia, R.1
Grote, P.2
Westermann, B.3
Conradt, B.4
-
14
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
W.J. Kaiser, J.W. Upton, A.B. Long, D. Livingston-Rosanoff, L.P. Daley-Bauer, R. Hakem, T. Caspary, and E.S. Mocarski RIP3 mediates the embryonic lethality of caspase-8-deficient mice Nature 471 2011 368 372
-
(2011)
Nature
, vol.471
, pp. 368-372
-
-
Kaiser, W.J.1
Upton, J.W.2
Long, A.B.3
Livingston-Rosanoff, D.4
Daley-Bauer, L.P.5
Hakem, R.6
Caspary, T.7
Mocarski, E.S.8
-
15
-
-
6344274848
-
Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, Opa1 in apoptosis
-
DOI 10.1091/mbc.E04-04-0294
-
Y.J. Lee, S.Y. Jeong, M. Karbowski, C.L. Smith, and R.J. Youle Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis Mol. Biol. Cell 15 2004 5001 5011 (Pubitemid 39392214)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.11
, pp. 5001-5011
-
-
Lee, Y.-J.1
Jeong, S.-Y.2
Karbowski, M.3
Smith, C.L.4
Youle, R.J.5
-
16
-
-
33845981493
-
L-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex
-
DOI 10.1074/jbc.M606539200
-
S.C. Lo, and M. Hannink PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex J. Biol. Chem. 281 2006 37893 37903 (Pubitemid 46042093)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.49
, pp. 37893-37903
-
-
Lo, S.-C.1
Hannink, M.2
-
17
-
-
42649130014
-
PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria
-
S.C. Lo, and M. Hannink PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria Exp. Cell Res. 314 2008 1789 1803
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 1789-1803
-
-
Lo, S.C.1
Hannink, M.2
-
18
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
DOI 10.1016/S0092-8674(03)00521-X
-
O. Micheau, and J. Tschopp Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes Cell 114 2003 181 190 (Pubitemid 36936912)
-
(2003)
Cell
, vol.114
, Issue.2
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
19
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
A. Oberst, C.P. Dillon, R. Weinlich, L.L. McCormick, P. Fitzgerald, C. Pop, R. Hakem, G.S. Salvesen, and D.R. Green Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis Nature 471 2011 363 367
-
(2011)
Nature
, vol.471
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
McCormick, L.L.4
Fitzgerald, P.5
Pop, C.6
Hakem, R.7
Salvesen, G.S.8
Green, D.R.9
-
20
-
-
0037424239
-
Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
-
DOI 10.1074/jbc.C200677200
-
A. Olichon, L. Baricault, N. Gas, E. Guillou, A. Valette, P. Belenguer, and G. Lenaers Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis J. Biol. Chem. 278 2003 7743 7746 (Pubitemid 36800505)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.10
, pp. 7743-7746
-
-
Olichon, A.1
Baricault, L.2
Gas, N.3
Guillou, E.4
Valette, A.5
Belenguer, P.6
Lenaers, G.7
-
21
-
-
79952291364
-
Molecular mechanisms and physiologic functions of mitochondrial dynamics
-
H. Otera, and K. Mihara Molecular mechanisms and physiologic functions of mitochondrial dynamics J. Biochem. 149 2011 241 251
-
(2011)
J. Biochem.
, vol.149
, pp. 241-251
-
-
Otera, H.1
Mihara, K.2
-
22
-
-
0035166814
-
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells
-
E. Smirnova, L. Griparic, D.L. Shurland, and A.M. van der Bliek Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells Mol. Biol. Cell 12 2001 2245 2256 (Pubitemid 33051954)
-
(2001)
Molecular Biology of the Cell
, vol.12
, Issue.8
, pp. 2245-2256
-
-
Smirnova, E.1
Griparic, L.2
Shurland, D.-L.3
Van Der Bliek, A.M.4
-
23
-
-
10644296253
-
Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis
-
DOI 10.1074/jbc.M408910200
-
R. Sugioka, S. Shimizu, and Y. Tsujimoto Fzo1, a protein involved in mitochondrial fusion, inhibits apoptosis J. Biol. Chem. 279 2004 52726 52734 (Pubitemid 39656648)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.50
, pp. 52726-52734
-
-
Sugioka, R.1
Shimizu, S.2
Tsujimoto, Y.3
-
24
-
-
84862907788
-
Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase
-
this issue
-
L. Sun, H. Wang, Z. Wang, S. He, S. Chen, D. Liao, L. Wang, J. Yan, W. Liu, X. Lei, and X. Wang Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase Cell 148 2011 213 227 this issue
-
(2011)
Cell
, vol.148
, pp. 213-227
-
-
Sun, L.1
Wang, H.2
Wang, Z.3
He, S.4
Chen, S.5
Liao, D.6
Wang, L.7
Yan, J.8
Liu, W.9
Lei, X.10
Wang, X.11
-
25
-
-
68149128514
-
Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1
-
K. Takeda, Y. Komuro, T. Hayakawa, H. Oguchi, Y. Ishida, S. Murakami, T. Noguchi, H. Kinoshita, Y. Sekine, and S. Iemura Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1 Proc. Natl. Acad. Sci. USA 106 2009 12301 12305
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 12301-12305
-
-
Takeda, K.1
Komuro, Y.2
Hayakawa, T.3
Oguchi, H.4
Ishida, Y.5
Murakami, S.6
Noguchi, T.7
Kinoshita, H.8
Sekine, Y.9
Iemura, S.10
-
26
-
-
33644763298
-
Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis
-
DOI 10.1128/MCB.26.6.2215-2225.2006
-
V. Temkin, Q. Huang, H. Liu, H. Osada, and R.M. Pope Inhibition of ADP/ATP exchange in receptor-interacting protein-mediated necrosis Mol. Cell. Biol. 26 2006 2215 2225 (Pubitemid 43346922)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.6
, pp. 2215-2225
-
-
Temkin, V.1
Huang, Q.2
Liu, H.3
Osada, H.4
Pope, R.M.5
-
27
-
-
78650718758
-
Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis
-
G. Trichonas, Y. Murakami, A. Thanos, Y. Morizane, M. Kayama, C.M. Debouck, T. Hisatomi, J.W. Miller, and D.G. Vavvas Receptor interacting protein kinases mediate retinal detachment-induced photoreceptor necrosis and compensate for inhibition of apoptosis Proc. Natl. Acad. Sci. USA 107 2010 21695 21700
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 21695-21700
-
-
Trichonas, G.1
Murakami, Y.2
Thanos, A.3
Morizane, Y.4
Kayama, M.5
Debouck, C.M.6
Hisatomi, T.7
Miller, J.W.8
Vavvas, D.G.9
-
29
-
-
45549098685
-
Molecular mechanisms and pathophysiology of necrotic cell death
-
DOI 10.2174/156652408784221306
-
N. Vanlangenakker, T. Vanden Berghe, D.V. Krysko, N. Festjens, and P. Vandenabeele Molecular mechanisms and pathophysiology of necrotic cell death Curr. Mol. Med. 8 2008 207 220 (Pubitemid 351982539)
-
(2008)
Current Molecular Medicine
, vol.8
, Issue.3
, pp. 207-220
-
-
Vanlangenakker, N.1
Vanden Berghe, T.2
Krysko, D.V.3
Festjens, N.4
Vandenabeele, P.5
-
30
-
-
43049152912
-
TNF-α Induces Two Distinct Caspase-8 Activation Pathways
-
DOI 10.1016/j.cell.2008.03.036, PII S0092867408005011
-
L. Wang, F. Du, and X. Wang TNF-alpha induces two distinct caspase-8 activation pathways Cell 133 2008 693 703 (Pubitemid 351636305)
-
(2008)
Cell
, vol.133
, Issue.4
, pp. 693-703
-
-
Wang, L.1
Du, F.2
Wang, X.3
-
31
-
-
73349091842
-
The role of mitochondria in apoptosis
-
C. Wang, and R.J. Youle The role of mitochondria in apoptosis Annu. Rev. Genet. 43 2009 95 118
-
(2009)
Annu. Rev. Genet.
, vol.43
, pp. 95-118
-
-
Wang, C.1
Youle, R.J.2
-
32
-
-
0035166812
-
Mammalian dynamin-like protein DLP1 tubulates membranes
-
Y. Yoon, K.R. Pitts, and M.A. McNiven Mammalian dynamin-like protein DLP1 tubulates membranes Mol. Biol. Cell 12 2001 2894 2905 (Pubitemid 33051952)
-
(2001)
Molecular Biology of the Cell
, vol.12
, Issue.9
, pp. 2894-2905
-
-
Yoon, Y.1
Pitts, K.R.2
McNiven, M.A.3
-
33
-
-
37549048249
-
The BCL-2 protein family: Opposing activities that mediate cell death
-
R.J. Youle, and A. Strasser The BCL-2 protein family: opposing activities that mediate cell death Nat. Rev. Mol. Cell Biol. 9 2008 47 59
-
(2008)
Nat. Rev. Mol. Cell Biol.
, vol.9
, pp. 47-59
-
-
Youle, R.J.1
Strasser, A.2
-
34
-
-
21244472965
-
Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis
-
DOI 10.1016/j.cell.2005.06.009, PII S0092867405005568
-
Q. Zhong, W. Gao, F. Du, and X. Wang Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis Cell 121 2005 1085 1095 (Pubitemid 40884398)
-
(2005)
Cell
, vol.121
, Issue.7
, pp. 1085-1095
-
-
Zhong, Q.1
Gao, W.2
Du, F.3
Wang, X.4
-
35
-
-
21244472965
-
Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis
-
DOI 10.1016/j.cell.2005.06.009, PII S0092867405005568
-
Zhong, Q.; Gao, W.; Du, F.; Wang, X. (2005). Mule/ARF-BP1, a BH3-Only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis. Cell 121, 1085-1095. (Pubitemid 40884398)
-
(2005)
Cell
, vol.121
, Issue.7
, pp. 1085-1095
-
-
Zhong, Q.1
Gao, W.2
Du, F.3
Wang, X.4
|