Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

Nature

Volumn 418, Issue 6894, 2002, Pages 191-195

  Scaffidi, Paola ^a   Misteli, Tom ^b   Bianchi, Marco E ^c  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b NATIONAL CANCER INSTITUTE   (United States)

^c VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; DNA;

INFLAMMATION;

PROTEINS;

CELL PROTEIN; CHROMATIN BINDING FACTOR; DNA; GENE PRODUCT; HIGH MOBILITY GROUP B1 PROTEIN; HIGH MOBILITY GROUP PROTEIN; NUCLEAR FACTOR; PROTEIN RAGE; UNCLASSIFIED DRUG;

BIOLOGY; DNA; PROTEIN;

APOPTOSIS; ARTICLE; AUTOLYSIS; BINDING AFFINITY; CELL DAMAGE; CELL DEATH; CELL KILLING; CELL NUCLEUS; CHROMATIN; CONTROLLED STUDY; CYTOARCHITECTURE; DEACETYLATION; GENE TARGETING; HUMAN; HUMAN CELL; INFLAMMATION; INJURY; MACROPHAGE; MONOCYTE; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN SECRETION; SIGNAL TRANSDUCTION;

ACETYLATION; ANIMALS; APOPTOSIS; CELL SURVIVAL; CHROMATIN; GENE DELETION; HELA CELLS; HMGB1 PROTEIN; HUMANS; INFLAMMATION; NECROSIS; PROTEIN BINDING; RATS;

EID: 0037062934     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/nature00858     Document Type: Article

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