Potential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseases

Journal of Molecular Medicine

Volumn 90, Issue 12, 2012, Pages 1361-1389

  Zhavoronkov, Alex ^a,b   Smit Mcbride, Zeljka ^c   Guinan, Kieran J ^b,d   Litovchenko, Maria ^a   Moskalev, Alexey ^b,e  

^a Center for Pediatric Hematology Oncology and Immunology   (Russian Federation)

^b Biogerontology Research Foundation   (United Kingdom)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d BIOATLANTIS LTD   (Ireland)

^e INSTITUTE OF BIOLOGY   (Russian Federation)

Author keywords

Age related diseases; Aging; Lamin A; Laminopathies; Progeria

Indexed keywords

5 AZA 2' DEOXYCYTIDINE; AZACITIDINE; CURCUMIN; LAMIN A; LAMIN B; MITHRAMYCIN; MONENSIN; N PHTHALOYLTRYPTOPHAN; NANAOMYCIN A; NIGERICIN; PARTHENOLIDE; PROCAINAMIDE; PROCAINE; PROMAZINE; PROMETHAZINE; PURPURIN; PYRIDINE DERIVATIVE; RESVERATROL; RILMENIDINE; ROTTLERIN; SAQUINAVIR; SORAFENIB; SPERMIDINE; STAUROSPORINE; TETRANDRINE; THALICARPINE; TRICHOSTATIN A; TRIFLUOPERAZINE; UNINDEXED DRUG; ZEBULARINE;

ABDOMINAL PAIN; AGING; AGITATION; ANEMIA; ANXIETY; APOPTOSIS; AUTOPHAGY; CELL CYCLE PROGRESSION; CELL INTERACTION; CELL PROLIFERATION; CHROMOSOME 1Q; CONSTIPATION; CONVULSION; COUGHING; DECREASED APPETITE; DIARRHEA; DIZZINESS; DNA DAMAGE; DNA REPAIR; DROWSINESS; ENDOPLASMIC RETICULUM STRESS; EPIGENETICS; FATIGUE; FEVER; GENE MUTATION; GENETIC CODE; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HAIR LOSS; HEADACHE; HORMONAL THERAPY; HUMAN; IMMUNE DEFICIENCY; LAMINOPATHY; LONGEVITY; MITOCHONDRIAL PERMEABILITY; MYALGIA; MYOGLOBINURIA; NAUSEA; NEUTROPENIA; NONHUMAN; NUCLEAR LAMINA; OXIDATIVE STRESS; PROGERIA; PROTEIN EXPRESSION; PROTEIN PROCESSING; RASH; REVIEW; SIDE EFFECT; SIGNAL TRANSDUCTION; THORAX PAIN; VOMITING; XEROSTOMIA;

AGING; ANIMALS; HUMANS; LAMIN TYPE A; PROGERIA;

EID: 84884212849     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-012-0962-4     Document Type: Review

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