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Volumn 4 S, Issue 2, 2012, Pages 453-460

Suppression of autophagy by BCR/ABL

Author keywords

Cell death; Leukemia; Oncogene; Review; Therapy

Indexed keywords

BCR ABL PROTEIN; CHLOROQUINE; IMATINIB; PROTEIN TYROSINE KINASE; ANTINEOPLASTIC AGENT; BENZAMIDE DERIVATIVE; PIPERAZINE DERIVATIVE; PROTEIN KINASE INHIBITOR; PYRIMIDINE DERIVATIVE;

EID: 84861734333     PISSN: 19450516     EISSN: 19450524     Source Type: Journal    
DOI: 10.2741/s278     Document Type: Article
Times cited : (11)

References (56)
  • 2
    • 0031031003 scopus 로고    scopus 로고
    • Clinical features at diagnosis in 430 patients with chronic myeloid leukaemia seen at a referral centre over a 16-year period
    • D. Savage, R. Szydlo, JM Goldman. Clinical features at diagnosis in 430 patients with chronic myeloid leukaemia seen at a referral centre over a 16-year period: Br J Haematol 96, 111-116 (1997)
    • (1997) Br J Haematol , vol.96 , pp. 111-116
    • Savage, D.1    Szydlo, R.2    Goldman, J.M.3
  • 3
    • 0029084364 scopus 로고
    • Clinical manifestations of chronic granulocytic leukemia
    • AS Spiers. Clinical manifestations of chronic granulocytic leukemia: Semin Oncol 22, 380-395 (1995)
    • (1995) Semin Oncol , vol.22 , pp. 380-395
    • Spiers, A.S.1
  • 4
    • 0022544401 scopus 로고
    • The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene
    • Y Ben-Neriah. GQ Daley, A. Mes-Masson, O. Witte, D Baltimore. The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene: Science 233, 212-214 (1986) (Pubitemid 16008117)
    • (1986) Science , vol.233 , Issue.4760 , pp. 212-214
    • Ben-Neriah, Y.1    Daley, G.Q.2    Mes-Masson, A.-M.3
  • 5
    • 0028980342 scopus 로고
    • Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis
    • D Cortez. L Kadlec, AM Pendergast: Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis. Mol Cell Biol 15, 5531-5541 (1995)
    • (1995) Mol Cell Biol , vol.15 , pp. 5531-5541
    • Cortez, D.1    Kadlec, L.2    Pendergast, A.M.3
  • 6
    • 0029087475 scopus 로고
    • Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene
    • A Goga. J McLaughlin, D. Afar, D. Saffran, ON Witte: Alternative signals to RAS for hematopoietic transformation by the BCR-ABL oncogene. Cell 82, 981-988 (1995)
    • (1995) Cell , vol.82 , pp. 981-988
    • Goga, A.1    McLaughlin, J.2    Afar, D.3    Saffran, D.4    Witte, O.N.5
  • 7
    • 0032886857 scopus 로고    scopus 로고
    • Biological consequences of the BCR/ABL fusion gene in humans and mice
    • MY Gordon: Biological consequences of the BCR/ABL fusion gene in humans and mice. J Clin Pathol 52, 719-722 (1999) (Pubitemid 29481328)
    • (1999) Journal of Clinical Pathology , vol.52 , Issue.10 , pp. 719-722
    • Gordon, M.Y.1
  • 8
    • 33947376040 scopus 로고    scopus 로고
    • Oncogenic signaling: New insights and controversies from chronic myeloid leukemia
    • DOI 10.1084/jem.20062335
    • RA Van Etten: Oncogenic signaling: new insights and controversies from chronic myeloid leukemia. J. Exp. Med. 204, 461-465 (2007) (Pubitemid 46457069)
    • (2007) Journal of Experimental Medicine , vol.204 , Issue.3 , pp. 461-465
    • Van Etten, R.A.1
  • 11
    • 15944404601 scopus 로고    scopus 로고
    • The development of Imatinib as therapeutic agent for chronic myeloid leukemia
    • M Deininger. E Buchdunger, BJ Druker: The development of Imatinib as therapeutic agent for chronic myeloid leukemia. Blood 108, 2640-2649 (2005)
    • (2005) Blood , vol.108 , pp. 2640-2649
    • Deininger, M.1    Buchdunger, E.2    Druker, B.J.3
  • 14
    • 0036493544 scopus 로고    scopus 로고
    • + acute lymphoblastic leukemia resistant to the tyrosine kinase inhibitor STI571 has a unique BCR-ABL gene mutation
    • DOI 10.1182/blood.V99.5.1860
    • W. Hofmann, L. Jones, N. Lemp, S d. Vos, H Gschaidmeier. D Hoelzer, O. Ottmann, HP Koeffler: Ph (+) acute lymphoblastic leukemia resistant to the tyrosine kinase inhibitor STI571 has a unique BCR-ABL gene mutation. Blood 99, 1860-1862 (2002) (Pubitemid 34533064)
    • (2002) Blood , vol.99 , Issue.5 , pp. 1860-1862
    • Hofmann, W.-K.1    Jones, L.C.2    Lemp, N.A.3    De Vos, S.4    Gschaidmeier, H.5    Hoelzer, D.6    Ottmann, O.G.7    Phillip Koeffler, H.8
  • 15
    • 10744232328 scopus 로고    scopus 로고
    • Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis
    • DOI 10.1182/blood-2002-09-2896
    • S Branford. Z Rudzki, S Walsh. I Parkinson, A Grigg. J Szer, K Taylor. R Hermann, J. Seymour, C Arthur. D Joske, K Lynch, T Hughes: Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis. Blood 102, 276-283 (2003) (Pubitemid 36759665)
    • (2003) Blood , vol.102 , Issue.1 , pp. 276-283
    • Branford, S.1    Rudzki, Z.2    Walsh, S.3    Parkinson, I.4    Grigg, A.5    Szer, J.6    Taylor, K.7    Herrmann, R.8    Seymour, J.F.9    Arthur, C.10    Joske, D.11    Lynch, K.12    Hughes, T.13
  • 16
    • 0348140591 scopus 로고    scopus 로고
    • Mechanisms and implications of imatinib resistance mutations in BCR-ABL
    • DOI 10.1097/00062752-200401000-00006
    • V Nardi. M Azam, GQ Daley: Mechanisms and implications of imatinib resistance mutations in BCR-ABL. Curr Opin Hematol 11, 35-43 (2004) (Pubitemid 38021719)
    • (2004) Current Opinion in Hematology , vol.11 , Issue.1 , pp. 35-43
    • Nardi, V.1    Azam, M.2    Daley, G.Q.3
  • 18
    • 0036090222 scopus 로고    scopus 로고
    • Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro
    • S. Graham, H. Jorgensen, E Allan. C Pearson, M. Alcorn, L Richmond, TL Holyoake: Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro. Blood 99, 319-325 (2002)
    • (2002) Blood , vol.99 , pp. 319-325
    • Graham, S.1    Jorgensen, H.2    Allan, E.3    Pearson, C.4    Alcorn, M.5    Richmond, L.6    Holyoake, T.L.7
  • 19
    • 3142676436 scopus 로고    scopus 로고
    • Overriding imatinib resistance with a novel ABL kinase inhibitor
    • DOI 10.1126/science.1099480
    • N. Shah, C Tran. FY Lee, P Chen. D Norris, CL Sawyers: Overriding imatinib resistance with a novel ABL kinase inhibitor. Science 305, 399-401 (2004) (Pubitemid 38938156)
    • (2004) Science , vol.305 , Issue.5682 , pp. 399-401
    • Shah, N.P.1    Tran, C.2    Lee, F.Y.3    Chen, P.4    Norris, D.5    Sawyers, C.L.6
  • 21
    • 34548825795 scopus 로고    scopus 로고
    • Bcr-Abl kinase domain mutations, drug resistance, and the road to a cure for chronic myeloid leukemia
    • DOI 10.1182/blood-2007-03-066936
    • T O'Hare. CA Eide, MW Deininger: Bcr-Abl kinase domain mutations, drug resistance, and the road to a cure for chronic myeloid leukemia. Blood 110, 2242-2249 (2007) (Pubitemid 47523141)
    • (2007) Blood , vol.110 , Issue.7 , pp. 2242-2249
    • O'Hare, T.1    Eide, C.A.2    Deininger, M.W.N.3
  • 23
    • 34247555482 scopus 로고    scopus 로고
    • Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies
    • DOI 10.1038/sj.leu.2404609, PII 2404609
    • X Jiang. Y Zhao, C Smith. M Gasparetto, A Turhan. A Eaves, C Eaves: Chronic myeloid leukemia stem cells possess multiple unique features of resistance to BCR-ABL targeted therapies. Leukemia 21, 926-935 (2007) (Pubitemid 46672068)
    • (2007) Leukemia , vol.21 , Issue.5 , pp. 926-935
    • Jiang, X.1    Zhao, Y.2    Smith, C.3    Gasparetto, M.4    Turhan, A.5    Eaves, A.6    Eaves, C.7
  • 24
    • 33744486584 scopus 로고    scopus 로고
    • Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction
    • M Copland. A Hamilton, L. Elrick, J. Baird, E. Allan, N Jordanides. M Barow, J. Mountford, TL Holyoake: Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction. Blood 107, 4532-453 (2006)
    • (2006) Blood , vol.107 , pp. 4532-4453
    • Copland, M.1    Hamilton, A.2    Elrick, L.3    Baird, J.4    Allan, E.5    Jordanides, N.6    Barow, M.7    Mountford, J.8    Holyoake, T.L.9
  • 25
    • 34247329753 scopus 로고    scopus 로고
    • + CML cells
    • DOI 10.1182/blood-2006-11-057521
    • H. Jorgensen, E. Allan, N. Jordanides, J. Mountford, TL Holyoake: Nilotinib exerts equipotent antiproliferative effects to imatinib and does not induce apoptosis in CD34+ CML cells. Blood 109, 4016-4019 (2007) (Pubitemid 46641755)
    • (2007) Blood , vol.109 , Issue.9 , pp. 4016-4019
    • Jorgensen, H.G.1    Allan, E.K.2    Jordanides, N.E.3    Mountford, J.C.4    Holyoake, T.L.5
  • 26
    • 42349116071 scopus 로고    scopus 로고
    • Enhanced BCR-ABL kinase inhibition does not result in increased inhibition of downstream signaling pathways or increased growth suppression in CML progenitors
    • DOI 10.1038/sj.leu.2405086, PII 2405086
    • H Konig. M Holtz, H Modi. P Manley, T. Holyoake, S. Forman, R Bhatia: Enhanced BCR-ABL kinase inhibition does not result in increased inhibition of downstream signaling pathways or increased growth suppression in CML progenitors. Leukemia 22, 748-755 (2008) (Pubitemid 351552624)
    • (2008) Leukemia , vol.22 , Issue.4 , pp. 748-755
    • Konig, H.1    Holtz, M.2    Modi, H.3    Manley, P.4    Holyoake, T.L.5    Forman, S.J.6    Bhatia, R.7
  • 27
    • 41349083561 scopus 로고    scopus 로고
    • Effective and selective inhibition of chronic myeloid leukemia primitive hematopoietic progenitors by the dual Src/Abl kinase inhibitor SKI-606
    • DOI 10.1182/blood-2007-05-092056
    • H Konig. TL Holyoake, R Bhatia: Effective and selective inhibition of chronic myeloid leukemia primitive hematopoietic progenitors by the dual Src/Abl kinase inhibitor SKI-606. Blood 111, 2329-2338 (2008) (Pubitemid 351451441)
    • (2008) Blood , vol.111 , Issue.4 , pp. 2329-2338
    • Konig, H.1    Holyoake, T.L.2    Bhatia, R.3
  • 28
    • 61849163272 scopus 로고    scopus 로고
    • Molecular biology of bcr/abl1-positive chronic myeloid leukemia
    • A Quintas-Cardama, J Cortes: Molecular biology of bcr/abl1-positive chronic myeloid leukemia. Blood 113, 1619-1630 (2009)
    • (2009) Blood , vol.113 , pp. 1619-1630
    • Quintas-Cardama, A.1    Cortes, J.2
  • 29
    • 79951489747 scopus 로고    scopus 로고
    • Chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCRABL activity
    • December 13, Epub ahead of print
    • A. Corbin, A Agarwal. M Loriaux, J Cortes. MW Deininger, BJ Druker: Chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCRABL activity. J. Clin. Invest. December 13, 2010 (Epub ahead of print)
    • (2010) J. Clin. Invest
    • Corbin, A.1    Agarwal, A.2    Loriaux, M.3    Cortes, J.4    Deininger, M.W.5    Druker, B.J.6
  • 30
    • 28544435485 scopus 로고    scopus 로고
    • Lysosomes and autophagy in cell death control
    • DOI 10.1038/nrc1738
    • G Kroemer, M Jaattela: Lysosomes and autophagy in cell death control. Nat Rev Cancer 2005;5:886-897. (Pubitemid 41746033)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.11 , pp. 886-897
    • Kroemer, G.1    Jaattela, M.2
  • 31
    • 35448981935 scopus 로고    scopus 로고
    • Autophagy: From phenomenology to molecular understanding in less than a decade
    • DOI 10.1038/nrm2245, PII NRM2245
    • DJ Klionsky: Autophagy: from phenomenology to molecular understanding in less than a decade. Nat Rev Mol Cell Biol 8, 931-937 (2007) (Pubitemid 47622558)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.11 , pp. 931-937
    • Klionsky, D.J.1
  • 32
    • 20344387475 scopus 로고    scopus 로고
    • Autophagy: Dual roles in life and death?
    • DOI 10.1038/nrm1666
    • EH Baehrecke: Autophagy: dual roles in life and death? Nat Rev Mol Cell Biol 6, 505-510 (2005) (Pubitemid 40780562)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.6 , pp. 505-510
    • Baehrecke, E.H.1
  • 33
    • 56749170677 scopus 로고    scopus 로고
    • Autophagic cell death: The story of a misnomer
    • G Kroemer, B Levine: Autophagic cell death: the story of a misnomer. Nat Rev Mol Cell Biol 9, 1004-1010 (2008)
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 1004-1010
    • Kroemer, G.1    Levine, B.2
  • 34
    • 25444440875 scopus 로고    scopus 로고
    • The role of autophagy in cancer development and response to therapy
    • DOI 10.1038/nrc1692, PII N1692
    • Y Kondo. T Kanzawa, R Sawaya, S Kondo: The role of autophagy in cancer development and response to therapy. Nat Rev Cancer 5, 726-734 (2005) (Pubitemid 41486365)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.9 , pp. 726-734
    • Kondo, Y.1    Kanzawa, T.2    Sawaya, R.3    Kondo, S.4
  • 35
    • 34548188741 scopus 로고    scopus 로고
    • Self-eating and self-killing: Crosstalk between autophagy and apoptosis
    • DOI 10.1038/nrm2239, PII NRM2239
    • M. Maiuri, E Zalckvar. A Kimchi, G Kroemer: Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 8, 741-752 (2007) (Pubitemid 47312826)
    • (2007) Nature Reviews Molecular Cell Biology , vol.8 , Issue.9 , pp. 741-752
    • Maiuri, M.C.1    Zalckvar, E.2    Kimchi, A.3    Kroemer, G.4
  • 36
    • 12944303650 scopus 로고    scopus 로고
    • Growth factor regulation of autophagy and cell survival in the absence of apoptosis
    • DOI 10.1016/j.cell.2004.11.046, PII S009286740401150X
    • J. Lum, D. Bauer, M Kong. MH Harris, C Li. T Lindsten, CB Thompson: Growth factor regulation of autophagy and cell survival in the absence of apoptosis. Cell 120, 237-248 (2005) (Pubitemid 40174766)
    • (2005) Cell , vol.120 , Issue.2 , pp. 237-248
    • Lum, J.J.1    Bauer, D.E.2    Kong, M.3    Harris, M.H.4    Li, C.5    Lindsten, T.6    Thompson, C.B.7
  • 37
    • 38149141767 scopus 로고    scopus 로고
    • Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis
    • K. Maclean, F. Dorsey, J. Cleveland, MB Kastan: Targeting lysosomal degradation induces p53-dependent cell death and prevents cancer in mouse models of lymphomagenesis. J. Clin Invest. 118, 79-88 (2008)
    • (2008) J. Clin Invest. , vol.118 , pp. 79-88
    • Maclean, K.1    Dorsey, F.2    Cleveland, J.3    Kastan, M.B.4
  • 44
    • 21444442926 scopus 로고    scopus 로고
    • Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells
    • H Ito. S Daido, T Kanzawa. S Kondo, Y Kondo: Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells. Int J Oncol 26, 1401-1410 (2005)
    • (2005) Int J Oncol , vol.26 , pp. 1401-1410
    • Ito, H.1    Daido, S.2    Kanzawa, T.3    Kondo, S.4    Kondo, Y.5
  • 45
    • 33847026354 scopus 로고    scopus 로고
    • Autophagy delays apoptotic death in breast cancer cells following DNA damage
    • M. Abedin, D Wang. MA McDonnell, U Lehmann, A Kelekar: Autophagy delays apoptotic death in breast cancer cells following DNA damage. Cell Death Differ 14, 500-510 (2007)
    • (2007) Cell Death Differ , vol.14 , pp. 500-510
    • Abedin, M.1    Wang, D.2    McDonnell, M.A.3    Lehmann, U.4    Kelekar, A.5
  • 46
    • 1842865745 scopus 로고    scopus 로고
    • Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells
    • DOI 10.1038/sj.cdd.4401359
    • T Kanzawa. IM Germano, T Komata. H Ito, Y Kondo, S Kondo: Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells. Cell Death Differ 11, 448-457 (2004) (Pubitemid 38489422)
    • (2004) Cell Death and Differentiation , vol.11 , Issue.4 , pp. 448-457
    • Kanzawa, T.1    Germano, I.M.2    Komata, T.3    Ito, H.4    Kondo, Y.5    Kondo, S.6
  • 47
    • 0038743077 scopus 로고    scopus 로고
    • Induction of autophagic cell death in malignant glioma cells by arsenic trioxide
    • T Kanzawa. Y Kondo, H Ito. S Kondo, I Germano: Induction of autophagic cell death in malignant glioma cells by arsenic trioxide. Cancer Res 63, 2103-2108 (2003) (Pubitemid 36538613)
    • (2003) Cancer Research , vol.63 , Issue.9 , pp. 2103-2108
    • Kanzawa, T.1    Kondo, Y.2    Ito, H.3    Kondo, S.4    Germano, I.5
  • 49
    • 57449120942 scopus 로고    scopus 로고
    • Autophagy-induced tumor dormancy in ovarian cancer
    • RK Amaravadi.: Autophagy-induced tumor dormancy in ovarian cancer. J. Clin. Invest. 118, 3837-3840 (2008)
    • (2008) J. Clin. Invest. , vol.118 , pp. 3837-3840
    • Amaravadi, R.K.1
  • 51
    • 77951750296 scopus 로고    scopus 로고
    • Selective autophagy in cancer development and therapy
    • I Dikic. T Johansen, T, V Kirkin: Selective autophagy in cancer development and therapy. Cancer Res. 70, 3431-3434 (2010)
    • (2010) Cancer Res. , vol.70 , pp. 3431-3434
    • Dikic, I.1    Johansen, T.2    Kirkin, T.V.3
  • 52
    • 2542500611 scopus 로고    scopus 로고
    • The biology of CML blast crisis
    • DOI 10.1182/blood-2003-12-4111
    • B Calabretta, D Perrotti: The biology of CML blast crisis. Blood 103, 4010-4022 (2004) (Pubitemid 38685338)
    • (2004) Blood , vol.103 , Issue.11 , pp. 4010-4022
    • Calabretta, B.1    Perrotti, D.2
  • 55
    • 67549142261 scopus 로고    scopus 로고
    • Life and death partners: Apoptosis, autophagy and the cross-talk between them
    • A Eisenberg-Lerner. S Bialik, A Kimchi: Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell Death Differ 16, 966-975 (2009)
    • (2009) Cell Death Differ , vol.16 , pp. 966-975
    • Eisenberg-Lerner, A.1    Bialik, S.2    Kimchi, A.3
  • 56
    • 32044465506 scopus 로고    scopus 로고
    • TOR signaling in growth and metabolism
    • DOI 10.1016/j.cell.2006.01.016, PII S0092867406001085
    • Wullschleger S. Loewith R. Hall M.N. 2006 TOR signaling in growth and metabolism. Cell 124:3 471-484.
    • (2006) Cell , vol.124 , Issue.3 , pp. 471-484
    • Wullschleger, S.1    Loewith, R.2    Hall, M.N.3


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