2-Deoxy-d-glucose activates autophagy via endoplasmic reticulum stress rather than ATP depletion

Cancer Chemotherapy and Pharmacology

Volumn 67, Issue 4, 2011, Pages 899-910

  Xi, Haibin ^a   Kurtoglu, Metin ^a   Liu, Huaping ^a   Wangpaichitr, Medhi ^b   You, Min ^a   Liu, Xiongfei ^c   Savaraj, Niramol ^b   Lampidis, Theodore J ^a  

^a UNIVERSITY OF MIAMI   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c DUKE UNIVERSITY   (United States)

Author keywords

2 Deoxy d glucose; ATP; Autophagy; Cell death; ER stress

Indexed keywords

3 METHYLADENINE; ADENOSINE TRIPHOSPHATE; CCAAT ENHANCER BINDING PROTEIN; CCAAT ENHANCER BINDING PROTEIN HOMOLOGOUS PROTEIN; DEOXYGLUCOSE; GLUCOSE REGULATED PROTEIN 78; MANNOSE; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 1 LIGHT CHAIN 3B; OXAMIC ACID; RAPAMYCIN; TUNICAMYCIN; UNCLASSIFIED DRUG;

ANAEROBIC GROWTH; ANTINEOPLASTIC ACTIVITY; ARTICLE; AUTOPHAGY; CANCER CELL; CELL DEATH; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; HYPOXIA; MELANOMA CELL; PRIORITY JOURNAL; UNFOLDED PROTEIN RESPONSE; UPREGULATION;

ADENOSINE TRIPHOSPHATE; ANTIMETABOLITES; APOPTOSIS; AUTOPHAGY; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL SURVIVAL; DEOXYGLUCOSE; ENDOPLASMIC RETICULUM; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MELANOMA; PANCREATIC NEOPLASMS; UNFOLDED PROTEIN RESPONSE;

EID: 79954450327     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-010-1391-0     Document Type: Article

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