Role of progerin-induced telomere dysfunction in HGPS premature cellular senescence

Journal of Cell Science

Volumn 123, Issue 15, 2010, Pages 2605-2612

  Benson, Erica K ^a   Lee, Sam W ^b   Aaronson, Stuart A ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Cellular senescence; DNA damage; Nuclear lamins; Telomerase; Telomere dysfunction; Tumor suppressors

Indexed keywords

NUCLEAR PROTEIN; PROGERIN; PROTEIN P53; RETINOBLASTOMA PROTEIN; TELOMERASE; UNCLASSIFIED DRUG;

ARTICLE; CELL AGING; CELL MATURATION; CELL PROLIFERATION; CHROMOSOME ABERRATION; CONTROLLED STUDY; DNA BINDING; DNA DAMAGE; GENE ACTIVATION; HUMAN; HUMAN CELL; HUTCHINSON SYNDROME; PREMATURE AGING; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; TELOMERE;

AGING, PREMATURE; CELL AGING; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; DNA DAMAGE; FLOW CYTOMETRY; HUMANS; IMMUNOBLOTTING; MICROSCOPY, CONFOCAL; NUCLEAR PROTEINS; PROGERIA; PROTEIN PRECURSORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TELOMERASE; TELOMERE;

EID: 77955385716     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.067306     Document Type: Article

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