Genome-environment interactions that modulate aging: Powerful targets for drug discovery

Pharmacological Reviews

Volumn 64, Issue 1, 2012, Pages 88-101

  de Magalhães, João Pedro ^a   Wuttke, Daniel ^a   Wood, Shona H ^a   Plank, Michael ^a   Vora, Chintan ^a,b  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b Xcelris Labs Ltd   (India)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; METFORMIN; MITOGEN ACTIVATED PROTEIN KINASE; RAPAMYCIN; RESVERATROL; SIRTUIN; SIRTUIN 1; SOMATOMEDIN C RECEPTOR; TARGET OF RAPAMYCIN KINASE; TRANSCRIPTION FACTOR FKHRL1;

AGING; ALLELE; ALZHEIMER DISEASE; BIOLOGY; BIOMANIPULATION; CALORIC RESTRICTION; DIET THERAPY; DIETARY INTAKE; DRUG INDUSTRY; DRUG TARGETING; ENVIRONMENTAL FACTOR; EPIGENETICS; FOOD INTAKE; GENE; GENE EXPRESSION; GENE INTERACTION; GENETIC ASSOCIATION; GENETICS; GENOMICS; GENOTYPE ENVIRONMENT INTERACTION; HEALTH; HEALTH CARE; INSULIN SENSITIVITY; LIFE EXTENSION; LIFESTYLE MODIFICATION; LONGEVITY; MALNUTRITION; NONHUMAN; PHARMACOLOGICAL PARAMETERS; PHARMACY; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; TEMPERATURE;

AGING; ANIMALS; CALORIC RESTRICTION; DRUG DISCOVERY; GENE-ENVIRONMENT INTERACTION; HEALTH; HUMANS;

EID: 83455179308     PISSN: 00316997     EISSN: 15210081     Source Type: Journal    
DOI: 10.1124/pr.110.004499     Document Type: Review

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