Common genomic variation in LMNA modulates indexes of obesity in Inuit

Journal of Clinical Endocrinology and Metabolism

Volumn 86, Issue 6, 2001, Pages 2747-2751

  Hegele, Robert A ^a   Huff, Murray W ^a   Young, T Kue ^b  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; LAMIN A; LAMIN C; PROTEIN LMNA; UNCLASSIFIED DRUG;

ADULT; ALLELE; ARTICLE; AUTOSOMAL DOMINANT DISORDER; BODY MASS; CANADA; ESKIMO; FEMALE; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; LIPODYSTROPHY; MAJOR CLINICAL STUDY; MALE; OBESITY; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT; SINGLE NUCLEOTIDE POLYMORPHISM; SKINFOLD THICKNESS;

ADULT; ALLELES; BODY MASS INDEX; FEMALE; GENE FREQUENCY; GENOME; GENOTYPE; HUMANS; INUITS; LAMININ; LAMINS; LEPTIN; MALE; MIDDLE AGED; NUCLEAR PROTEINS; OBESITY; PHENOTYPE; SEX CHARACTERISTICS; SKINFOLD THICKNESS; VARIATION (GENETICS);

EID: 0034974846     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.86.6.2747     Document Type: Article

References (12)

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2. Sociocultural and behavioural determinants of obesity among Inuit in the central
3. Obesity in northern Canadian Indians: Patterns, determinants, and consequences
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6. Partial lipoatrophy with insulin resistant diabetes and hyperlipidemia (Dunnigan syndrome)
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8. Nuclear lamin A/C R482Q mutation in Canadian kindreds with Dunnigan-type familial partial lipodystrophy
9. Genetic variation in LMNA modulates plasma leptin and indices of obesity in aboriginal Canadians
10. Structural organization of the human gene encodIng nuclear lamin A and nuclear lamin C
11. An autosomal genomic scan for loci linked to type II diabetes mellitus and body-mass index in Pima Indians