Progeria syndromes and ageing: What is the connection?

Nature Reviews Molecular Cell Biology

Volumn 11, Issue 8, 2010, Pages 567-578

  Burtner, Christopher R ^a   Kennedy, Brian K ^a,b,c  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^c GUANGDONG MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LAMIN A; LAMIN C; PROTEIN FARNESYLTRANSFERASE INHIBITOR; SOMATOMEDIN C; TARGET OF RAPAMYCIN KINASE;

AGING; CELL AGING; CELL METABOLISM; CELL PROLIFERATION; CLINICAL TRIAL; CONCEPTUAL FRAMEWORK; DISEASE ASSOCIATION; DNA DAMAGE; DNA REPAIR; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXPERIMENTAL MODEL; GENE MUTATION; GENETIC MODEL; GENOMIC INSTABILITY; HOMEOSTASIS; HUMAN; LIFESPAN; LONGEVITY; MESENCHYMAL STEM CELL; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MECHANICS; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PREMATURE AGING; PRIORITY JOURNAL; PROGERIA; REVIEW; SIGNAL TRANSDUCTION; TELOMERE; WERNER SYNDROME;

AGING; ANIMALS; DNA DAMAGE; DNA REPAIR; EVOLUTION; HUMANS; LAMIN TYPE A; LONGEVITY; MESENCHYMAL STEM CELLS; MODELS, BIOLOGICAL; PROGERIA; SIGNAL TRANSDUCTION; SIROLIMUS; SYNDROME;

EID: 77954950116     PISSN: 14710072     EISSN: 14710080     Source Type: Journal    
DOI: 10.1038/nrm2944     Document Type: Review

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