Endoplasmic reticulum stress-induced cysteine protease activation in cortical neurons: Effect of an Alzheimer's disease-linked presenilin-1 knock-in mutation

Journal of Biological Chemistry

Volumn 276, Issue 48, 2001, Pages 44736-44743

  Siman, Robert ^a   Flood, Dorothy G ^b   Thinakaran, Gopal ^c   Neumar, Robert W ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b CEPHALON INC   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; MUTAGENESIS; NEUROLOGY; PROTEINS;

PROTEOLYSIS;

DISEASES;

CALPAIN; CASPASE 3; CASPASE 6; CHAPERONE; CYSTEINE PROTEINASE; PRESENILIN 1; PROCASPASE 12; PROTEINASE; UNCLASSIFIED DRUG; CARRIER PROTEIN; CASPASE; CASPASE 12; CPP32 PROTEIN; EIF 2 KINASE; GLUCOSE REGULATED PROTEIN; GLUCOSE REGULATED PROTEINS; GLUCOSE-REGULATED PROTEINS; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEINS 70; IMMUNOGLOBULIN HEAVY CHAIN-BINDING PROTEIN; MEMBRANE PROTEIN; PERK KINASE; PROTEIN SERINE THREONINE KINASE; S182 PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN CELL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME LOCALIZATION; IMMUNOCYTOCHEMISTRY; MOUSE; MUTATION; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN INDUCTION; STRESS; ANIMAL; CELL CULTURE; CELL FRACTIONATION; ENZYMOLOGY; GENETICS; GLYCOSYLATION; HUMAN; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; METABOLISM; NERVE CELL; PROTEIN TERTIARY STRUCTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSLATION;

ANIMALIA;

ALZHEIMER DISEASE; ANIMAL; APOPTOSIS; CALPAIN; CARRIER PROTEINS; CASPASES; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; EIF-2 KINASE; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; GLYCOSYLATION; HEAT-SHOCK PROTEINS 70; HUMAN; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; MICE; MOLECULAR CHAPERONES; MUTATION; NEURONS; PROTEIN STRUCTURE, TERTIARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STRESS; SUBCELLULAR FRACTIONS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSLATION, GENETIC;

EID: 0035976923     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104092200     Document Type: Article

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